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Use Of Swine Small Intestine Submucosa As A Dermal Suture, Paige E. Black
Use Of Swine Small Intestine Submucosa As A Dermal Suture, Paige E. Black
PCOM Biomedical Studies Student Scholarship
The purpose of this preliminary study is to determine if swine small intestine submucosa (SIS) can be used to create a suture that will perform comparably to commercially available chromic gut sutures when placed into a wound in rat dermis. This study is part of an ongoing collaboration that has explored SIS as a biologic scaffold in various tissues and surgical procedures. In this study, eight Sprague-dawley rats were divided into two groups, each receiving a full thickness skin wound between the scapula, made by a 5mm biopsy punch. The wound was then closed with commercially available chromic gut suture, …