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Full-Text Articles in Analytical, Diagnostic and Therapeutic Techniques and Equipment

Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian Dec 2023

Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian

Biomedical Engineering: Graduate Reports and Projects

As the prevalence of cardiovascular diseases continues to exponentially grow in populations across the globe, the necessity of determining underlying factors, effective methods of diagnoses, and universally available preventive measures also grows. Early detection of endothelial dysfunction, a proven precursor of cardiovascular diseases, can be extremely impactful in encouraging preventative measures and early intervention before medical conditions become chronic. In recent years, ice plunging, a form of cryotherapy involving full body immersion in cold water, has gained popularity within circles of fitness and health practitioners, gaining the interest of people of all backgrounds. Certain parallels observed between the human physiological …


Research Model Applications In The Investigation Of Vascular Disease Treatments, Alex Anthony Dangler Jan 2023

Research Model Applications In The Investigation Of Vascular Disease Treatments, Alex Anthony Dangler

Dissertations and Theses

Cardiovascular disease (CVD) is a pressing global health issue with significant socioeconomic consequences. Within the spectrum of CVDs, peripheral artery disease (PAD) and aortic disease necessitate the development of effective and safe treatments. To achieve this, various research models are employed to investigate molecular mechanisms of cells, understand cellular interactions in vascular diseases, assess biocompatibility, and test and evaluate medical devices. This dissertation examines research models and their applications in the advancement of treatments for vascular diseases. For the evaluation of liposome delivery systems in PAD, an ApoE-/- cellular mouse model was employed to investigate the cellular uptake of liposomes …