Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Intracranial Eeg Patient Analysis: Seizure Reduction In Refractory Epilepsy Following Depth Electrode Insertion, Shreyashish Roy-Chowdhury

Undergraduate Student Research Internships Conference

Rationale: The implantation effect describes an immediate reduction in seizure frequency following the insertion of intracranial electrodes. There is limited information regarding which patients will experience a reduction of seizures and the reason for the implantation effect. This study focuses on describing predictor factors for the reduction in seizure frequency in patients with medically resistant epilepsy implanted with depth electrodes.

Methods: We conducted a retrospective chart review of 89 patients who underwent intracranial electroencephalography (iEEG) monitoring with depth electrodes. Sixty-five of these patients had no subsequent therapeutic interventions and had a 3-6 month follow-up. Patients were grouped as either responders …

Epilepsy Risk Among Survivors Of Intensive Care Unit Hospitalization For Sepsis, Tresah C. Antaya, Britney N. Allen, Lucie Richard, Salimah Z. Shariff, Gustavo Saposnik, Jorge Burneo

Neuroepidemiology Research Unit Project Summaries

Research Summary: Key Findings

• 407 (0.28%) patients developed epilepsy within 2 years of their ICU discharge, 103 (25.3%) of whom were exposed to sepsis.
• Sepsis survivors were significantly more likely to develop epilepsy, relative to non-septic ICU survivors.
• Among sepsis survivors, epilepsy risk increased with age and was higher among those with chronic kidney disease.

7t Magnetic Resonance Spectroscopy Of Non-Lesional Temporal Lobe Epilepsy, John Robert Adams

Electronic Thesis and Dissertation Repository

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy, and one that is generally amenable to surgical treatment when surgery is necessary. Unfortunately, roughly 25-30% of the patient population have no visible lesions on clinical MRI scans. Without anatomical abnormalities to help guide surgical resection, the success of surgical treatment decreases substantially. However, metabolic abnormalities may exist that could allow for accurate localization of epileptic tissue in this cohort. Magnetic resonance spectroscopy (MRS) is a technique that can detect and measure the concentration of metabolically important molecules within tissue, giving insight into the underlying cellular metabolism.

In …