Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Relief Of Cervicogenic Headaches After Single-Level And Multilevel Anterior Cervical Diskectomy: A 5-Year Post Hoc Analysis, Jonathan J. Liu, Gilbert Cadena, Ripul R. Panchal, Rudolph J. Schrot, Kee D. Kim

Faculty Publications & Research of the TUC College of Osteopathic Medicine

Study Design Prospective study.

Objective Because single-level disk arthroplasty or arthrodesis in the lower subaxial spine improves headaches after surgery, we studied whether this effect may be better appreciated after two-level arthroplasty.

Methods We performed an independent post hoc analysis of two concurrent prospective randomized investigational device exemption trials for cervical spondylosis, one for single-level treatment and the other for two adjacent-level treatments.

Results For the one-level study, baseline mean headache scores significantly improved at 60 months for both the cervical disk arthroplasty (CDA) and anterior cervical diskectomy and fusion (ACDF) groups (p < 0.0001). However, mean improvement in headache scores was not statistically different between the investigational and control groups from 6 months through 60 months. For the two-level study, baseline mean headache scores significantly improved at 60 months for both the CDA and ACDF groups (p < 0.0001). The CDA group demonstrated greater improvement from baseline at all points; this difference was statistically significant at 6, 12, 24, 36, and 48 months but not at 18 and 60 months.

Conclusion Both CDA and ACDF at either …