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Diffusion Modeling And Device Development For Peritoneal Membrane Oxygenation, Liana Hatoum
Diffusion Modeling And Device Development For Peritoneal Membrane Oxygenation, Liana Hatoum
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Acute respiratory distress syndrome (ARDS) is a pulmonary disease that causes hypoxemia and respiratory failure. The mortality rate for ARDS ranges between 27% and 45%. Current treatments including mechanical ventilation and extracorporeal membrane oxygenation (ECMO) are often associated with high risk complications including barotrauma, infection, thrombosis, and hemorrhage. Alternative pulmonary support techniques are needed to improve the survival rate of patients suffering from ARDS. Previous studies introducing pure O2 gas, perfluorocarbons and red blood cells into the intraperitoneal (IP) cavity have reported no effect or only a mild increase in oxygenation. Here we report peritoneal membrane oxygenation (PMO) using …