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Full-Text Articles in Alternative and Complementary Medicine

The Role Of Spirituality And 12 Step Groups In Addressing Treatment Fear And Worry Among Head And Neck Cancer Patients, Heather M. Wallace Oct 2019

The Role Of Spirituality And 12 Step Groups In Addressing Treatment Fear And Worry Among Head And Neck Cancer Patients, Heather M. Wallace

Funded Articles

Diagnosis of head and neck squamous cell carcinoma (HNSCC) presents a multifarious problem. Because of uncertainty regarding appropriate clinical treatment, as well as the high potential for disfigurement and functional loss resulting in diminished quality of life (QOL), satisfactory patient participation in quality decision-making is critical. Previous research has consistently revealed that older adults frequently defer decisionmaking to their physician and make decisions more quickly than younger adults. Research also suggests that lay health beliefs, past experiences and various strategies of emotional regulation, based on perceptions of the quantity and quality of remaining time till death, may influence the decisionmaking …


Effectiveness And Mechanism Of Action Of Modified Porphyrins For Photodynamic Therapy Of Triple Negative Breast Cancer Cells, Hannah Brandon Jan 2019

Effectiveness And Mechanism Of Action Of Modified Porphyrins For Photodynamic Therapy Of Triple Negative Breast Cancer Cells, Hannah Brandon

Honors Theses

Triple negative breast cancer (TNBC) is a particularly aggressive form of breast cancer that lacks the three molecules typically targeted for treatment. Standard treatment methods leave much to be desired--the rates of metastasis and recurrence are high and the prognosis for most patients with TNBC is poor. One potential treatment for TNBC is photodynamic therapy (PDT), which uses compounds called photosensitizers that are taken up by all tissues in the body. The tumor is exposed to light, activating the photosensitizer and creating reactive oxygen species that cause cell death. This method is relatively pain-free, effective, and does not harm cells …


Killing Breast Cancer One Porphyrin At A Time, Taylor C. Lymburner Jan 2019

Killing Breast Cancer One Porphyrin At A Time, Taylor C. Lymburner

Honors Theses

New treatments for cancer are continuously being developed and improved. One such treatment is Photodynamic Therapy, more commonly referred to as PDT. PDT is quickly becoming more popular due to its relative lack of side effects that are present in other treatments. In PDT, light-sensitive agents are required and are activated by light in the targeted cells. There are many types of PDT agents but the one focused on in this research is a four-pyrrole ring structure known as a porphyrin. The combination of H2 TPPC with 3- amino-oxetane-3-yl-methanol created the final product ofH2TPP-Oxo-MeOH. Once the porphyrin was formed, it …