Alternative and Complementary Medicine Commons^™

Lc-Ms/Ms Identification Of A Bromelain Peptide Biomarker From Ananas Comosus Merr, Eric R. Secor, Steven M. Szczepanek, Linda Guernsey, Prabitha Natarajan, Karim Rezaul, David K. Han, Roger S. Thrall, Lawrence K. Silbart

UCHC Articles - Research

Bromelain (Br) is a cysteine peptidase (GenBank AEH26024.1) from pineapple, with over 40 years of clinical use. The constituents mediating its anti-inflammatory activity are not thoroughly characterized and no peptide biomarker exists. Our objective is to characterize Br raw material and identify peptides in the plasma of Br treated mice. After SDS-PAGE in-gel digestion, Br (VN#3507; Middletown, CT, USA) peptides were analyzed via LC/MS/MS using 95% protein probability, 95% peptide probability, and a minimum peptide number = 5. Br spiked mouse plasma (1 ug/ul) and plasma from i.p. treated mice (12 mg/kg) were assessed using SRM. In Br raw material, …

Music Therapy And Quality Of Life: The Effects Of Musical Interventions On Self-Reported And Caregiver-Reported Quality Of Life In Older Adults With Symptoms Of Dementia, Alisha Snyder

Masters Theses

The purpose of this study was to determine the effects of music therapy on the quality of life of people with symptoms of dementia. Both self-reported and caregiver-reported quality of life scores were recorded before and after an eight-week treatment period. A control group of discussion and an experimental group of music therapy were included in the study, with a sample size of N = 13. Analysis of the data was done with t tests. No statistical significance was found when comparing the average quality of life scores in the discussion group or the music therapy group from pretest to …

Music Therapy In The Nicu: Interventions And Techniques In Current Practice And A Survey Of Experience And Designation Implications, Suzanna A. Peczeniuk-Hoffman

Masters Theses

While researchers have documented the clinical use of music in medical settings, little is known about music therapists working in the Neonatal Intensive Care Unit (NICU). The purpose of the study was to examine the demographics, educational training (NICU-MT designation), employment conditions, and music therapy interventions/techniques used by professional music therapists in the NICU. A 15- item survey was designed and electronically mailed to music therapists (N = 318) identified by the American Music Therapy Association (AMTA), the Certification Board for Music Therapists (CBMT), and Infant and Child Medical Music Therapy Institute at Florida State University as potentially working with …

A Comprehensive Study Of Ayurveda, Traditional Chinese Medicine, And Comparison, Per Maximilian Gasseholm

Social Sciences

Today complimentary medicine is being increasingly sought out. Ayurveda and TCM, are among the oldest systems of medicine and have been developed for over thousands of years in India and China respectively. This paper details the philosophies, medical theories, anatomy, diagnosis, and treatments of both of these systems, including a comparison. Both of these modalities of healing operate with a microcosm – macrocosm paradigm. This makes them fundamentally similar, and compatible with each other. Ayurveda uses Tridoshic theory to apply treatments ranging from diet, massage, meditation, yoga among other therapies to bring Vata, Pitta, and Kapha into balance. TCM is …

Building A Strategic Framework For Comparative Effectiveness Research In Complementary And Integrative Medicine, Claudia M. Witt, Margaret Chesney, Richard Gliklich, Lawrence Green, George Lewith, Bryan Luce, Anne Mccaffrey, Shelly Rafferty Withers, Harold C. Sox, Sean Tunis, Brian M. Berman

Dartmouth Scholarship

The increasing burden of chronic diseases presents not only challenges to the knowledge and expertise of the professional medical community, but also highlights the need to improve the quality and relevance of clinical research in this domain. Many patients now turn to complementary and integrative medicine (CIM) to treat their chronic illnesses; however, there is very little evidence to guide their decision-making in usual care. The following research recommendations were derived from a CIM Stakeholder Symposium on Comparative Effectiveness Research (CER): (1) CER studies should be made a priority in this field; (2) stakeholders should be engaged at every stage …

Editorial, R Manchanda

Indian Journal of Research in Homoeopathy

No abstract provided.

Morpho-Anatomy Of Leaf, Stem And Root Of Alternanthera Sessilis (L.) R. Br. Ex Dc And Alternanthera Pungens Kunth (Amaranthaceae) And Its Significance In Drug Identification, H Gupta, J Raj, A Rathi, E Sundaram, S Kumar, R Manchanda

Indian Journal of Research in Homoeopathy

The present communication deals with morpho-anatomical characters of leaf, stem and root of Alternanthera sesilis and Alternanthera pungens and its signifinace in identification and differentiation of raw drug originated from these species. The plant characters of diagnostic importance are for example colour of stem is green in Alternanthera sesilis and brown in Alternanthera pungens; flower of Alternanthera sesilis possess three stamens while Alternanthera pungens possess five stamens. The study will be useful in confirming the authenticity of raw drug and also serve as a reference for advanced studies of these two such closely related species.

Homoeopathic Individualized Lm-Potencies Versus Centesimal Potencies For Pain Management Of Cervical Spondylosis: A Multicenter Prospective Randomized Exploratory Clinical Study, C Nayak, Vikram Singh, Jaya Gupta, Mohd Ali, Ramendar Pal, Md Arya, P Bindu, Debdatta Nayak, Paromita Goswami

Indian Journal of Research in Homoeopathy

Objective:Primary objective was to assess the feasibility for a further definite study to compare the effectiveness of LM-vs-CM homoeopathic potencies in reducing pain due to cervical spondylosis. Method:A multi center prospective randomized clinical pilot study was conducted by Central Council for Research in Homoeopathy at its three centers during June 2009 - June 2010. Out of 148 patients screened, 56 patients were enrolled and randomized as per the pre-set inclusion criteria. However 54 patients, LM group (n=28) and CM group (n=26) were analyzed. Pain was assessed using visual analog scale. The primary end point for pain from 1 to 60 …

Clinical Verification Of Ichthyolum - A Multicentric Observational Study, P Chakraborty, Subhash Kaushik, S Nain, Pramodji Singh, Ojit Singh, K Das, Darshan Singh, V Singh, M Rai

Indian Journal of Research in Homoeopathy

Introduction: Ichthyolum is reported to have pronounced action on various systemic affections in various literatures. On the basis of this literature, Council conducted a thorough proving on this drug earlier and subsequently clinical verification, to ascertain its clinical importance in Homoeopathy. Objectives:The primary objective was to clinically verify the symptomatology of Ichthyolum as observed during its proving conducted by Council on this drug and the secondary objective was to ascertain the clinical symptoms. Method:In the multicentre study, a total of 131 patients from all age groups & both sexes were enrolled from the O.P.D.s of the respective institutes & units …

Ccrh Quarterly Bulletin (1982), S Sharma

Indian Journal of Research in Homoeopathy

No abstract provided.

Pharmacological Actions Of Homoeopathic Drugs, Eswara Das

Indian Journal of Research in Homoeopathy

No abstract provided.

A Multicentric, Double-Blind Randomized, Homoeopathic Pathogenetic Trial Of Caesalpinia Bonducella, Rajpal Rajpal, Vinay Singh, V Siddiqui, C Nayak, A Majumdar, P Chandra, J Singh, S Pathak, G Rakshit

Indian Journal of Research in Homoeopathy

Objective:To elicit the pathogenetic response of Caesalpinia bonducella in homoeopathic potencies on healthy human volunteers. Methodology:The drug Caesalpinia bonducella was proved by the Central Council for Research in Homoeopathy (CCRH) through randomized, double-blind, placebo-controlled design. The proving was conducted at three centres. The drug was proved in 6 & 30 centesimal potencies on 50 apparently healthy volunteers, declared eligible after their pre-trial medical examinations by the medical specialists and routine laboratory investigations. In first phase of proving, provers were given 56 doses of placebo divided in 04 doses per day for 14 days. In next two phases, 56 doses of …

Anabolic And Androgenic Effects Of Certain Atriplex Species Grown In Egypt, Dina M. El-Kersh, Fatma S. El-Sakhawy, Dina R. Abou-Hussein, Amany A. Sleem

Pharmacy

20-Hydroxyecdysone (20-HE) was detected by TLC in the ethyl acetate fraction of two Atriplex species grown in Egypt: A. lindleyi subsp. inflata and A. leucoclada. EIA quantification of 20-HE proved its presence in a concentration of 9.15 and 7.3 μg/g dried aerial parts in each of the two species, respectively. Significant anabolic and androgenic activities were demonstrated for 20-HE comparing to testosterone; the study also revealed that the total alcohol extract and the ethyl acetate fraction of A. lindleyi subsp. inflata exhibited greater activities than their analogues in A. leucoclada. Column chromatographic fractionation of the ethyl acetate fraction of the …

Titcomb, John M., B. 1814? (Sc 756), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid and scan (Click on "Additional Files" below) for Manuscripts Small Collection 756. Medical remedies and recipes collected in a small notebook of John M. Titcomb of Baltimore, Maryland.

We Are… Bridging Medicine And Science Vol. 1, Issue 2, Fall 2012, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.

Edible Marijuana: A New Frontier In The Culinary World, Ariella H. Wolkowicz

Honors Theses - Providence Campus

Cannabis, commonly known as marijuana, has a rich history as a source of fiber, food and medicine (Li 437). Since 1785, physicians and scientists alike have worked to discover the active chemical components and medical effectiveness of this plant (Touw 2; Aldrich). Despite its complicated legal history, marijuana has retained a place culturally and, in some countries, scientifically as an effective medical agent. As a medically edible ingredient, cannabis has also been more recently heralded as a new, even cutting edge flavor, opening a new frontier to the culinary community.

After the isolation of the main active ingredient in cannabis, …

The Effect Of Vessel Depth, Diameter, And Location On Ultrasound-Guided Peripheral Intravenous Catheter Longevity., J Matthew Fields, Anthony J Dean, Raleigh W Todman, Arthur K Au, Kenton L Anderson, Bon S Ku, Jesse M Pines, Nova L Panebianco

Department of Emergency Medicine Faculty Papers

INTRODUCTION: Ultrasound-guided peripheral intravenous catheters (USGPIVs) have been observed to have poor durability. The current study sets out to determine whether vessel characteristics (depth, diameter, and location) predict USGPIV longevity.

METHODS: A secondary analysis was performed on a prospectively gathered database of patients who underwent USGPIV placement in an urban, tertiary care emergency department. All patients in the database had a 20-gauge, 48-mm-long catheter placed under ultrasound guidance. The time and reason for USGPIV removal were extracted by retrospective chart review. A Kaplan-Meier survival analysis was performed.

RESULTS: After 48 hours from USGPIV placement, 32% (48/151) had failed prematurely, 24% …

A Multi-Centric, Double-Blind Randomized, Homoeopathic Pathogenetic Trial Of Buxus Sempervirens, Rajpal Rajpal, Vinay Singh, V Siddiqui, C Nayak, A Majumdar, P Chandra, S Dey, P Sivadas

Indian Journal of Research in Homoeopathy

Objective:To elicit the pathogenetic response of Buxus sempervirens Linn. in homoeopathic potencies on healthy human volunteers. Methodology: Buxus sempervirens drug was proved by the Central Council for Research in Homoeopathy (CCRH) through randomized, double-blind, placebo-controlled method. The proving was conducted at three centres during 2007-08. The drug was proved in 6 & 30 centesimal potencies on 57 apparently healthy volunteers, declared eligible after their pre-trial medical examination by the medical specialists and routine laboratory investigations. In its first phase of proving, volunteers were given 56 doses of placebo divided in 4 doses per day for 14 days. In the next …

Standardisation And Quality Control Of Homoeopathic Drug Pimenta Officinalis Lindl, P Rao, P Subramanian, P Sudhakar, T Reddy, P Reddy, H Gupta

Indian Journal of Research in Homoeopathy

Pimenta officinalis Lindl., a bushy tree commonly known as ′all spice′ belongs to the family Myrtaceae. It is a potential drug in homoeopathy used in neuralgias and disturbed sensations of heat and cold. The dried unripe fruits are used as medicine. The fruit is a small pea-sized berry, blackish to reddish brown. The epicarp is conspicuous with numerous large glandular secretory cavities. The pericarp is about 2 mm thick. The mesocarpic cells contain resin, tannins and sphaerocrystals. Stone cells are also present in mesocarp. The outermost layer of seed consists of closely packed testa with attached stone cells. The endosperm …

Homoeopathic Medicines In The Management Of Benign Prostatic Hyperplasia: A Multicentric Prospective Observational Study, Praveen Oberai, Varanasi Roja, D Ramesh, D Arya, G Reddy, S Sharma, Chaturbhuja Nayak, Vikram Singh, Hari Singh

Indian Journal of Research in Homoeopathy

Objectives:The primary objective of this study was to determine the therapeutic usefulness of a group of predefined trial medicines in benign prostatic hyperplasia. The secondary objective was to check the progression of disease by evaluating changes in prostate volume (PV), post-void residual urine (PVRU) and peak urine flow rates (Qmax and Qavg in ml/sec). Methods:In a multi-centric observational study, 231 patients suffering from benign prostatic hyperplasia (BPH) having prostate volume > 20 mL and prostate specific antigen (PSA) ≤ 4 ng/mL were enrolled at 5 Institutes/Units under Central Council for Research in Homeopathy (CCRH). Symptoms were analyzed using the American Urological …

An Evidence Based Case Study Of Benign Prostatic Hyperplasia, Girish Gupta, Santosh Singh

Indian Journal of Research in Homoeopathy

Benign prostatic hyperplasia (BPH) has been the most frequent reason for elderly men undergoing surgery. BPH symptoms range from least voiding difficulties to urinary retention and renal failure. In this case of BPH, subjective measures such as changes in International Prostatic Symptom Score / American Urological Association Assessment (IPSS/AUA), and objective measures such as changes in prostate size and urinary flow rate were assessed, as the successful management and treatment of BPH should seek both to improve symptoms and prevent disease progression. The case was treated with Lycopodium, a homoeopathic medicine reported here. This case shows the efficacy of medicine …

Ccrh Quarterly Bulletin (1979-81), V Singh

Indian Journal of Research in Homoeopathy

No abstract provided.

Editorial, R Manchanda

Indian Journal of Research in Homoeopathy

No abstract provided.

Homeopathy Emerging As Nanomedicine, Rajendra Upadhyay, Chaturbhuja Nayak

Indian Journal of Research in Homoeopathy

Background:Homeopathy is a time-tested two-century old empirical system of healing. Homeopathic medicines are prepared through a characteristic process known as potentization, where serial dilutions are performed with strong strokes at each step of dilution. Homeopathy is controversial because most medicines do not contain one single molecule of the corresponding starting-substance. Aim:To investigate a possible nanoscience mechanism of action of homeopathic medicines. Methodology: Ultra-pure samples were prepared and were examined under scanning (SEM) and transmission electron microscope (TEM) along with selected area nanodiffraction (SAD) and energy-dispersive X-ray analysis (EDX). Also trace element analysis (TEA) for silicon was performed. Results:Homeopathic medicines showed …

Disease Monograph — Urolithiasis, Seema Rai

Indian Journal of Research in Homoeopathy

No abstract provided.

Increased Susceptibility To Metabolic Syndrome In Adult Offspring Of Angiotensin Type 1 Receptor Autoantibody-Positive Rats., Suli Zhang, Xi Zhang, Lihong Yang, Zi Yan, Li Yan, Jue Tian, Xiaoyu Li, Li Song, Li Wang, Xiaoli Yang, Ronghua Zheng, Wayne Bond Lau, Xinliang Ma, Huirong Liu

Department of Emergency Medicine Faculty Papers

Abstract Aims: Abnormal fetal and early postnatal growth is closely associated with adult-onset metabolic syndrome (MetS). However, the underlying etiological factors remain complex. The presence of the autoantibody against the angiotensin II type 1 receptor (AT1-Ab), a known risk factor for pre-eclampsia, may create a suboptimal intrauterine fetal environment. The current study investigated whether middle-aged offspring of AT1-Ab-positive mothers were prone to metabolic disorder development. Results: The AT1-Abs was detected in placental trophoblastic cells, capillary endothelium, and milk of pregnant rats actively immunized with the second extracellular loop of the AT1 receptor. AT1-Abs in newborn rats induced vasoconstriction, increased intracellular-free …

Green Tea Extract Protects Against Fibrogenesis Associated With Nonalcoholic Fatty Liver Disease In Diet-Induced Obese Rats, Allyson M. Bower

Master's Theses

No abstract provided.

Effects Of Reiki, Yoga, Or Meditation On The Physical And Psychological Symptoms Of Chemotherapy-Induced Peripheral Neuropathy: A Randomized Pilot Study, Paul G. Clark, Geronima Cortese-Jimenez, Eric Cohen

Sociology, Anthropology and Social Work Faculty Research and Scholarship

Three complementary approaches for managing physical and psychological symptoms related to chemotherapy-induced peripheral neuropathy were evaluated against an education-only control arm. This study included 26 participants who were randomly assigned to weekly, hour-long sessions of yoga, Reiki, meditation, or an educational control experience for 6 weeks. Each participant completed pre–post measures of neurotoxicity, quality of life, psychological distress, and mindfulness. Descriptive analysis of the data indicated that all experimental group participants demonstrated improved within-group scores on quality of life and neurotoxicity outcomes following intervention; however, the improvements were not statistically significant. Neurotoxicity worsened significantly in the control group, but there …

Editorial, Alok Kumar

Indian Journal of Research in Homoeopathy

No abstract provided.

Role Of Homoeopathic Medicines In Treating Uterine Fibroid: A Prospective Observational Study, Iqbal Quadri, M Shahid Ali, B Vatsalya, Hima Ponnam, Nikhat S

Indian Journal of Research in Homoeopathy

Background & objective: Uterine fibroids (UF) or leiomyomas are found in 25% to 35% women of reproductive age. It is one of the most common indications for hysterectomy further leading to complications. The present observational study on UF was undertaken to arrive at a group of useful homoeopathic medicines for the treatment of the same. Methods: A prospective observational study was conducted at Princess Durru Shehvar Children′s and General Hospital, Hyderabad in coordination with its Extension Unit of Drug Standardization Unit (Hyderabad) of Central Council for Research in Homoeopathy during September 2006 - August 2009. One hundred and thirty eight …