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Marshall University

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Full-Text Articles in Alternative and Complementary Medicine

We Are… Bridging Medicine And Science, Vol. 1, Issue 4, Fall 2015, Marshall University Biomedical Sciences Oct 2015

We Are… Bridging Medicine And Science, Vol. 1, Issue 4, Fall 2015, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.

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We Are… Bridging Medicine And Science, Vol. 1, Issue 3, Fall 2013, Marshall University Biomedical Sciences Oct 2013

We Are… Bridging Medicine And Science, Vol. 1, Issue 3, Fall 2013, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.

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We Are… Bridging Medicine And Science Vol. 1, Issue 2, Fall 2012, Marshall University Biomedical Sciences Oct 2012

We Are… Bridging Medicine And Science Vol. 1, Issue 2, Fall 2012, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

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We Are… Bridging Medicine And Science Vol. 1, Issue 1, Fall 2011, Marshall University Biomedical Sciences Oct 2011

We Are… Bridging Medicine And Science Vol. 1, Issue 1, Fall 2011, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.

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Ca2+ Signaling Modulates Cytolytic T Lymphocyte Effector Functions, Mark T. Esser, Doris M. Haverstick, Claudette L. Fuller, Charles A. Gullo Phd, Vivian Lam Braciale Apr 1998

Ca2+ Signaling Modulates Cytolytic T Lymphocyte Effector Functions, Mark T. Esser, Doris M. Haverstick, Claudette L. Fuller, Charles A. Gullo Phd, Vivian Lam Braciale

Biochemistry and Microbiology

Cytolytic T cells use two mechanisms to kill virally infected cells, tumor cells, or other potentially autoreactive T cells in short-term in vitro assays. The perforin/granule exocytosis mechanism uses preformed cytolytic granules that are delivered to the target cell to induce apoptosis and eventual lysis. FasL/Fas (CD95 ligand/CD95)–mediated cytolysis requires de novo protein synthesis of FasL by the CTL and the presence of the death receptor Fas on the target cell to induce apoptosis. Using a CD8+ CTL clone that kills via both the perforin/granule exocytosis and FasL/Fas mechanisms, and a clone that kills via the FasL/Fas mechanism only, …

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