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Full-Text Articles in Medicine and Health Sciences
Plasmapheresis For The Treatment Of Repeated Early Pregnancy Wastage Associated With Anti-P, J. Rock, R. Shirey, H. Braine, P. Ness, T. Kickler, Jennifer Niebyl
Plasmapheresis For The Treatment Of Repeated Early Pregnancy Wastage Associated With Anti-P, J. Rock, R. Shirey, H. Braine, P. Ness, T. Kickler, Jennifer Niebyl
Jennifer R Niebyl
It has been proposed that the blood group antibody, anti-P, produced by p or Pk individuals may cause abortion early in pregnancy. The authors have studied and successfully treated a Pk woman with anti-P who had 13 consecutive first-trimester miscarriages. Anti-P was implicated as the cause of repeated pregnancy loss after extensive clinical, endocrinologic, immunologic, and chromosomal evaluations. To remove P blood group antibodies, plasmapheresis was begun at five weeks' gestation during the 14th pregnancy with one plasma volume exchange two to three times per week. This therapy resulted in a reduction in the titer of anti-P, and the patient …
Premature Rupture Of The Membranes And Prolonged Latency, J. Johnson, N. Daikoku, Jennifer Niebyl, T. Johnson, V. Khouzami, F. Witter
Premature Rupture Of The Membranes And Prolonged Latency, J. Johnson, N. Daikoku, Jennifer Niebyl, T. Johnson, V. Khouzami, F. Witter
Jennifer R Niebyl
The aim of this retrospective study in 8320 patients with premature rupture of the membranes (PROM) was to determine the consequences of prolongation of the latent period. Among patients with pregnancies of more than 37 weeks' duration, those with PROM and latent periods of more than 1 day demonstrated an increased incidence of intrapartum fever (IPF), whereas those with latent periods of more than 3 days demonstrated a marked increase in fetal (but not neonatal) deaths. Although IPF and perinatal mortality were more common in preterm pregnancies, neither was found to increase or decrease with prolonged latency, provided differences in …
A False Negative Oxytocin Challenge Test, W. Mccranie, Jennifer Niebyl
A False Negative Oxytocin Challenge Test, W. Mccranie, Jennifer Niebyl
Jennifer R Niebyl
A negative oxytocin challenge test has been considered a very reassuring finding in managing pregnancies in which the fetus is at risk from uteroplacental insufficency. In the case described here a fetal death in utero occurred 4 days after a negative oxytocin challenge test in a Class D diabetic patient, but in that period of time the patient's metabolic status deteriorated. A negative oxytocin challenge test does not protect the fetus from a subsequent acute event such as abruptio placentae, a cord accident, or diabetic ketoacidosis.
Pregnancy In Sickle Cell Disease, S. Charache, Jennifer Niebyl
Pregnancy In Sickle Cell Disease, S. Charache, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Adolescent Pregnancy And Abortion, D. Youngs, Jennifer Niebyl
Adolescent Pregnancy And Abortion, D. Youngs, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Doppler Ultrasound And Maternal Erythrocyte Fragility, G. Bause, Jennifer Niebyl, R. Sanders
Doppler Ultrasound And Maternal Erythrocyte Fragility, G. Bause, Jennifer Niebyl, R. Sanders
Jennifer R Niebyl
Maternal erythrocyte fragility was studied in eight controls and in 16 women exposed to Doppler ultrasound monitoring during labor. Blood samples were taken before and after Doppler monitoring and no significant change in erythrocyte fragility was seen, although there was a trend toward increased fragility in patients exposed continuously for more than seven hours.
The Accuracy Of Visual And Meter Determinations Of Blood Glucose With The Use Of Chemstrip Bg, G. Marquette, T. Dillard, S. Bietla, Jennifer Niebyl
The Accuracy Of Visual And Meter Determinations Of Blood Glucose With The Use Of Chemstrip Bg, G. Marquette, T. Dillard, S. Bietla, Jennifer Niebyl
Jennifer R Niebyl
The 95% confidence intervals for the blood glucose determinations with use of the Chemstrip bG were +/- 28 mg/dl by visual reading and +/- 18 mg/dl by means of the Accu-Chek photometer. These rapid methods continue to be an important aid in the home care of pregnant diabetic women.
Prostaglandin F Metabolite Concentration As A Prognostic Factor In Preterm Labor, C. Weitz, R. Ghodgaonkar, N. Dubin, Jennifer Niebyl
Prostaglandin F Metabolite Concentration As A Prognostic Factor In Preterm Labor, C. Weitz, R. Ghodgaonkar, N. Dubin, Jennifer Niebyl
Jennifer R Niebyl
Concentration of the 13,14-dihydro,15 keto-metabolite of prostaglandin F2 alpha (PGFM) was measured in women being observed for preterm labor. The mean initial PGFM level was significantly higher in patients who delivered preterm (65.9 +/- 9.7 pg/mL; N = 14) than in patients not in preterm labor (32.1 +/- 4.3 pg/mL; N = 11; P less than .01). Plasma PGFM concentrations decreased significantly during ritodrine therapy only in successfully treated patients (P less than .05). All patients with initial PGFM concentrations greater than or equal to 55 pg/mL delivered preterm. Two of four patients not considered to be in preterm labor …
Treatment Of Premature Labor With Indomethacin, D. Blake, Jennifer Niebyl, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner
Treatment Of Premature Labor With Indomethacin, D. Blake, Jennifer Niebyl, R. White, K. Kumor, N. Dubin, J. Robinson, P. Egner
Jennifer R Niebyl
No abstract provided.
Marijuana Use In Pregnancy And Pregnancy Outcome, F. Witter, Jennifer Niebyl
Marijuana Use In Pregnancy And Pregnancy Outcome, F. Witter, Jennifer Niebyl
Jennifer R Niebyl
A retrospective analysis utilizing historical data collected as part of our computerized data base was performed to assess the impact of marijuana use in pregnancy on pregnancy outcome. Records of 8350 patients were reviewed and 417 patients gave a history of only marijuana use for a prevalence of 5%. There was no association between marijuana use and prematurity or congenital anomalies. Marijuana use was strongly associated with the use of alcoholic beverages and smoking. Previously reported associations may represent the concomitant use of these other drugs.
Multiple Pregnancy With Late Death Of One Fetus, P. Cherouny, I. Hoskins, T. Johnson, Jennifer Niebyl
Multiple Pregnancy With Late Death Of One Fetus, P. Cherouny, I. Hoskins, T. Johnson, Jennifer Niebyl
Jennifer R Niebyl
Twenty cases of fetal death complicating a multiple pregnancy after 20 weeks' gestation are reviewed. We evaluated gestational age at diagnosis and delivery (29.3 +/- 0.7 and 31.8 +/- 0.9 weeks, respectively), interval from diagnosis to delivery (2.6 +/- 0.6 weeks), and cause of fetal death as a group and by type of placentation (76.5% monochorionic). Eighty-five percent of the surviving fetuses were delivered preterm, and the four neonatal deaths were all due to extreme prematurity, with a mean (+/- SEM) birth weight of 794 +/- 237 g. Perinatal mortality was 585 per 1000, 450 for twin A and 750 …
Randomized Comparative Trial Of Indomethacin And Ritodrine For The Long-Term Treatment Of Preterm Labor, R. Besinger, Jennifer Niebyl, W. Keyes, T. Johnson
Randomized Comparative Trial Of Indomethacin And Ritodrine For The Long-Term Treatment Of Preterm Labor, R. Besinger, Jennifer Niebyl, W. Keyes, T. Johnson
Jennifer R Niebyl
A randomized prospective trial was performed to compare the efficacy and safety of ritodrine and indomethacin in the long-term treatment of preterm labor. Forty patients with intact membranes in preterm labor at 23 to 34 weeks' gestation were randomized to receive either intravenous ritodrine or oral indomethacin as the first-line tocolytic agent. Successful intravenous ritodrine therapy was followed by oral terbutaline therapy, and indomethacin-treated patients continued to receive oral indomethacin. Treatment failures were defined as progressive preterm labor or patient intolerance, and these patients were treated with intravenous magnesium sulfate. Ritodrine and indomethacin were equally successful in delaying preterm birth …
Severe Lead Poisoning Caused By Use Of Health Supplements Presenting As Acute Abdominal Pain During Pregnancy, A. Shamshirsaz, J. Yankowitz, Asha Rijhsinghani, A. Greiner, S. Holstein, Jennifer Niebyl
Severe Lead Poisoning Caused By Use Of Health Supplements Presenting As Acute Abdominal Pain During Pregnancy, A. Shamshirsaz, J. Yankowitz, Asha Rijhsinghani, A. Greiner, S. Holstein, Jennifer Niebyl
Jennifer R Niebyl
BACKGROUND: The public and some health care providers regard complementary and alternative medications as safe. There is no scientific basis for that belief, but there is evidence of poor quality control and toxicity of some remedies. CASE: A white pregnant woman presented with diffuse, acute abdominal pain ultimately diagnosed as lead poisoning due to the use of traditional Asian Indian health supplements. CONCLUSION: Use of traditional medicines may extend beyond the ethnic group in which the traditional medicine originated. When symptoms warrant, poisoning with lead or other heavy metals should be considered in the differential diagnosis.
Drug Therapy During Pregnancy, Jennifer Niebyl
Drug Therapy During Pregnancy, Jennifer Niebyl
Jennifer R Niebyl
A randomized prospective trial has shown that folic acid started before conception and continued for the first trimester reduces the risk of recurrence of neural tube defects by 72% in women with a previously affected child. Carbamazepine exposure in utero is associated with a 1% risk of spina bifida. Long-term follow-up of antenatal exposure to phenobarbital and carbamazepine in two groups of infants shows no neurologic differences between the two groups. Magnesium sulfate is more effective in prevention of recurrent eclamptic seizures than phenytoin. During pregnancy, the need for thyroxine increases in many women. Vitamin B6 and ginger are both …
Carbamazepine Levels In Pregnancy And Lactation, Jennifer Niebyl, D. Blake, J. Freeman, R. Luff
Carbamazepine Levels In Pregnancy And Lactation, Jennifer Niebyl, D. Blake, J. Freeman, R. Luff
Jennifer R Niebyl
An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation. Blood levels of primidone decreased during pregnancy and rose postpartum requiring dosage adjustments. Pharmacologically insignificant amounts of the drug were detected in breast milk. A review of the literature revealed 94 infants exposed to carbamazepine in utero and no evidence to date that this drug carries a teratogenic risk.
Preterm Parturition. Prostaglandin Synthetase Inhibitors, Jennifer Niebyl
Preterm Parturition. Prostaglandin Synthetase Inhibitors, Jennifer Niebyl
Jennifer R Niebyl
No abstract provided.
Vitamin B6 Is Effective Therapy For Nausea And Vomiting Of Pregnancy: A Randomized, Double-Blind Placebo-Controlled Study, V. Sahakian, D. Rouse, S. Sipes, N. Rose, Jennifer Niebyl
Vitamin B6 Is Effective Therapy For Nausea And Vomiting Of Pregnancy: A Randomized, Double-Blind Placebo-Controlled Study, V. Sahakian, D. Rouse, S. Sipes, N. Rose, Jennifer Niebyl
Jennifer R Niebyl
Fifty-nine women completed a randomized, double-blind placebo-controlled study of pyridoxine hydrochloride (vitamin B6) for the treatment of nausea and vomiting of pregnancy. Thirty-one patients received vitamin B6, 25-mg tablets orally every 8 hours for 72 hours, and 28 patients received placebo in the same regimen. Patients were categorized according to the presence of vomiting: severe nausea (score greater than 7) or mild to moderate nausea (score of 7 or less). The severity of nausea (as graded on a visual analogue scale of 1-10 cm) and the number of patients with vomiting over a 72-hour period were used to evaluate response …
Teenage Pregnancy, D. Youngs, Jennifer Niebyl
Vulvar Carcinoma With Hypercalcemia, Jennifer Niebyl, Rene Genadry, E. Friedrich, E. Wilkinson, J. Woodruff
Vulvar Carcinoma With Hypercalcemia, Jennifer Niebyl, Rene Genadry, E. Friedrich, E. Wilkinson, J. Woodruff
Jennifer R Niebyl
Hypercalcemia associated with nonmetastatic malignancy has been reported most frequently with lung or kidney tumors, while among gynecologic malignancies, the ovary has been the most common primary site. The pertinent clinicopathologic features of 2 cases of nonmetastatic vulvar carcinoma producing hypercalcemia are described in the present report. Including 3 previously reported cases, the vulva is seen to be the second most common site in the female genital tract for production of this paraendocrine syndrome. The clinician should be aware of the association of hypercalcemia and mental confusion with bulky vulvar tumors, so that surgery will not needlessly be delayed in …