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Articles 11911 - 11911 of 11911
Full-Text Articles in Medicine and Health Sciences
The Parenchymal Cells Of The Rat Pineal Gland, E Tapp, M Blumfield
The Parenchymal Cells Of The Rat Pineal Gland, E Tapp, M Blumfield
Faculty, Staff and Students Publications
Background: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare hematologic disorder with improved survival due to advancements in treatment. However, long-term cardiovascular morbidity and mortality remain significant. Established cardiovascular risk calculators, such as the 2008 Framingham Heart Study (FHS) global cardiovascular disease (CVD) and the American College of Cardiology/American Heart Association (ACC/AHA) atherosclerotic CVD (ASCVD) risk estimators, may not adequately account for the elevated and unique cardiovascular risks in iTTP survivors.
Objectives: To evaluate the discrimination and calibration of the ACC/AHA ASCVD and FHS global CVD models in predicting major adverse cardiovascular events (MACEs) among iTTP survivors.
Methods: This retrospective …