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Full-Text Articles in Medicine and Health Sciences
Paraoxonase 1, Hdl Subclasses And Post Surgery Acute Inflammation: A Pilot Study., Yasmin Bains, Russell Caccavello, Kazuhiko Kotani, Alejandro Gugliucci
Paraoxonase 1, Hdl Subclasses And Post Surgery Acute Inflammation: A Pilot Study., Yasmin Bains, Russell Caccavello, Kazuhiko Kotani, Alejandro Gugliucci
Faculty Publications & Research of the TUC College of Osteopathic Medicine
High density lipoproteins (HDL) structure and function studies are needed to better understand the heterogeneous nature of the HDL particle, and its interaction with associated proteins such as apolipoprotein A-1 (ApoA-1), paraoxonase 1 (PON1) and the environment. Our study assesses the effects of acute inflammation on PON1 and HDL subclasses in post-surgical colorectal cancer patients. PON1 was measured kinetically through its arylesterase and lactonase activity and HDL sub-classes were measured using Quantimetrix Lipoprint® System. White blood cells (WBC) counts, c-reactive protein (CRP) and serum amyloid A (SAA) levels were also analyzed using standard techniques. Our findings show that baseline …
Colorectal Cancer On The Decline, Albert B. Lowenfels, Patrick Maisonneuve, Ravinder Mamtani
Colorectal Cancer On The Decline, Albert B. Lowenfels, Patrick Maisonneuve, Ravinder Mamtani
NYMC Faculty Publications
No abstract provided.
Correlation Of Ischemia-Modified Albumin With Sofa And Apache Ii Scores In Preoperative Patients With Colorectal Cancer, Masaaki Katoh, Kazuhiko Kotani, Alejandro Gugliucci, Hisanaga Horie, Russell Caccavello, Mamoru Takeuchi
Correlation Of Ischemia-Modified Albumin With Sofa And Apache Ii Scores In Preoperative Patients With Colorectal Cancer, Masaaki Katoh, Kazuhiko Kotani, Alejandro Gugliucci, Hisanaga Horie, Russell Caccavello, Mamoru Takeuchi
Faculty Publications & Research of the TUC College of Osteopathic Medicine
Purpose. Critical illnesses are assessed according to the sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II. Circulating ischemia-modified albumin (IMA) is a biomarker generated under ischemic and oxidative conditions and may reflect disease severity in preoperative patients. This study investigated the correlations of IMA with SOFA and APACHE II scores in inpatients admitted for colorectal surgery. Methods.We examined 27 patients with advanced colorectal cancers (mean age 69 years, men/women = 15/12). Correlations between SOFA and APACHE II scores in addition to preoperative serum IMA and C-reactive protein (CRP) levels were analyzed. Results …