Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Modulatory Effects Of Pg102 (Actinidia Arguta) On Inflammatory Cytokine Mrna Expression In Canine Atopic Dermatitis, Yong-Uk Lee, Seol-Hee Park, Eui-Hwa Nam, Tae-Ho Chung, Cheol-Yong Hwang
Modulatory Effects Of Pg102 (Actinidia Arguta) On Inflammatory Cytokine Mrna Expression In Canine Atopic Dermatitis, Yong-Uk Lee, Seol-Hee Park, Eui-Hwa Nam, Tae-Ho Chung, Cheol-Yong Hwang
The Thai Journal of Veterinary Medicine
Canine atopic dermatitis (AD) is a common, chronic relapsing inflammatory skin disease. An aqueous extract, PG102, derived from Actinidia arguta fruit, has been investigated as an anti-inflammatory agent in humans and atopy-like animal models, but its underlying mechanism for canine AD treatment has not been fully understood. This study evaluated the in vitro anti-inflammatory effect of PG102 with respect to the representative allergy-related cytokine panel from dust mite allergen extract (DME)-stimulated peripheral blood mononuclear cells (PBMCs) of canine AD patients using quantitative real-time PCR. PBMCs were isolated from eight dogs with definite diagnoses of AD and stimulated with DME for …