Medicine and Health Sciences Commons^™

2300 Ferry, Kylie Miskovic

Purdue Journal of Service-Learning and International Engagement

Gateway to Hope is the syringe service program located at 2300 Ferry Street that provides not only syringes and other sterile medical equipment for injections but also wound cleaning, medications, and even toiletries. People can also receive basic health services there, and for many people who access these services, this is the only time they interact with the health care system. Located in the same building is the Recovery Café, a welcoming space for anyone in recovery from substance use disorders and anything else. Available to members of either organization is the clothing closet, where people can come and get …

A Reflection On What Pharmacists In Different Countries Can Learn From One Another, Aaryaman Khurana, Patricia Darbishire

Purdue Journal of Service-Learning and International Engagement

What would be the first words that come to mind if you were asked about the US health care system? I asked that question to several of my friends and pharmacy peers and received mixed responses such as “expensive,” “confusing,” “hard to navigate,” and “best in the world.” This was not surprising considering the many options and the varying quality of medical procedures, medical devices, and pharmaceuticals available. I wondered how responses might differ if I posed the same question about their health care to those in a third-world country. So, I asked the same question of friends and family …

Changing Minds And Lives: A Substance Use Awareness Campaign, Alyssa Collins, Claire Wolfer-Jenkins, Rachel Isaac

Purdue Journal of Service-Learning and International Engagement

Introduction: In 2024, 48.4million Americans experienced a substance use disorder (SUD),with opioid use disorder representing a significant concern. In 2024, an estimated 8 million individuals misused opioids, contributing to 54,743 fatal overdoses. College students are particularly vulnerable, with 20% reporting illicit substance use within the past month, highlighting the urgent need for focused interventions in this population.

Project Overview: Boiler Substance Awareness Network (BSAN) is a campus initiative funded by the Lead Forward Fellowship grant. BSAN educates the Purdue community about SUD to reduce stigma and foster a recovery-friendly environment. The focus is on two objectives: preparing students to respond …

Bridging Gaps In Preventative Care: Pharmacy Students' Impact Through Point-Of-Care Testing And Education At Recovery Café Lafayette, Katherine Davis, Jailyn Jones

Purdue Journal of Service-Learning and International Engagement

Final-year student pharmacists Katherine and Jailyn served on the executive committee of Purdue’s chapter of the American Pharmacists Association–Academy of Student Pharmacists (APhA-ASP) as president and patient care vice president, respectively, during the 2023–2024 academic year. After striving for more community-based involvement with the APhA-ASP chapter, Katherine and Jailyn combined efforts and passions to serve the community by providing health services to a local community center. Preventative health services are vital for patients and also provide substantial benefit to students who are able to practice real-world counseling skills through these opportunities. Throughout the Doctor of Pharmacy curriculum at Purdue, Katherine …

Roseman University Research Symposium, Dustin Ruiz Edmonds, Nicholas Hill, Riley Grant Fisher, David Sant, Andrew Fisher

Annual Research Symposium

No abstract provided.

Cancer Treatment Induced Skeletal Muscle Loss As A Predictor Of Late Cardiotoxicity In Aya: A Pilot Study, Savannah V. Rauschendorfer, Efstratios Koutroumpakis, Behrang Amini, Juhee Song, Michelle Hildebrandt, Anita Deswal Md Mph, J. Andrew Livingston, Michael Roth, Eugenie S. Kleinerman Md

Cancer Survivorship Research Retreat

No abstract provided.

A Scarring Experience: Pelvic Floor Rehabilitation As A Novel Palliative Approach In Colorectal Cancer Survivorship, Aryan Dowlatshahi, Leanne Jackson, Mary Garcia

Cancer Survivorship Research Retreat

This is a discussion of the novel approach of pelvic floor rehabilitation in its utility specifically for colorectal cancer survivorship which will be additionally presented at the MD Anderson Survivorship Research Retreat conference.

Osteopathic Manipulative Medicine As An Adjunctive Approach To Improve Pelvic Perfusion And Fertility-Related Physiologic Markers, Ashton Dodd, Yanielisse Bellinger, Marsha Chevalier, Annaliese Taylor, Jacob Warner-Palacio, Aurora Jeanes, Nathan Barnhurst

Annual Research Symposium

No abstract provided.

Electronic Cigarette Use And Clinically Assessed Oral Mucosal Lesions In Adults: A Systematic Review, Kevin K. Zhang, Kamran Awan

Annual Research Symposium

Abstract

Background: Electronic cigarette (e-cigarette) use among adults has risen rapidly over the past decade, prompting concern about potential adverse effects on oral health. Although the systemic consequences of e-cigarette exposure have been increasingly studied, effects on the oral mucosa remain less clearly defined. Existing investigations describe a range of oral mucosal findings, but reported outcomes and assessment methods are inconsistent, making it difficult to draw clear conclusions.

Objectives: To systematically review the available evidence examining the association between electronic cigarette use and oral mucosal lesions/alterations in adults, compared with non-users or other tobacco exposure groups.

Methods: A systematic literature …

Propofol In Chronic Cannabis Users: A Mechanistic Link To Cannabinoid Hyperemesis?, Jonmark I. Dolendo, Sonia Frick, Jia Q. Yang, Brad A. Haubrich

Annual Research Symposium

Purpose: Cannabinoid hyperemesis syndrome (CHS) is characterized by cyclic nausea, vomiting, and abdominal pain in chronic cannabis users, often relieved by exposure to hot water. Propofol, a widely used GABAergic anesthetic with antiemetic properties, has paradoxically been implicated in exacerbating hyperemetic episodes in some cannabis users. With the growing legalization of marijuana and social acceptance to its recreational use it is believed that this phenomenon will be more ubiquitous to clinicians. This review aims to investigate the mechanistic and clinical evidence linking propofol administration to CHS and to summarize strategies for prevention, diagnosis, and management.

Methods: PubMed and EBSCO were …

Racing Against Time: Simultaneous Anterior And Inferior St-Elevation Myocardial Infarction Managed With The Nano-Crush Bifurcation Stenting Technique, Selim Süleyman Sert, Fatih Aksoy

Journal of the Saudi Heart Association

We present a rare case of simultaneous anterior and inferior ST-elevation myocardial infarction caused by the acute occlusion of both the right coronary artery and the left anterior descending artery. The culprit LAD lesion involved a true bifurcation, which was successfully treated using the nano-crush stenting technique, achieving complete reperfusion. This case highlights the feasibility of complex bifurcation intervention in a hemodynamically unstable patient with double-vessel STEMI. It underscores the importance of rapid diagnosis, aggressive revascularization, and appropriate stenting strategy in managing multivessel acute myocardial infarction.

Executive Leadership System Improvement Program Proposal For Capturing At-Risk Patients In A Primary Care Setting, Winter Wilson

Walden Dissertations and Doctoral Studies

Unmet social determinants of health (SDOH) contribute significantly to poor health outcomes, increased healthcare utilization, and persistent inequities in access to care. In a primary care organization, the inconsistent identification and management of patients’ social needs resulted in variable documentation, limited referrals to social work services, and avoidable emergency department (ED) utilization. The purpose of this Doctor of Nursing Practice (DNP) project was to develop an executive leadership systems implementation proposal to standardize the identification and referral of at-risk patients through the integration of a validated social needs screening tool into the electronic health record (EHR). The guiding practice-focused question …

Staff Education To Improve Provider Knowledge In Addressing Sdoh-Related Barriers Affecting Medication Adherence, Andrea Latimore

Walden Dissertations and Doctoral Studies

This Doctoral of Nursing Practice (DNP) project focused on improving provider knowledge in addressing social determinants of health (SDOH) that contribute to medication nonadherence. There is a gap in provider knowledge in addressing SDOH-related barriers that contributes to poor health outcomes. Increasing provider awareness of SDOH improves patient outcomes. The practice-focused question guiding this doctoral project asked whether an educational module on SDOH improved provider knowledge in addressing SDOH-related barriers to medication adherence among adult patients with chronic illnesses. The program consisted of a pretest, an educational module delivered via a PowerPoint presentation, and a posttest. A total of 20 …

Staff Education To Improve Knowledge Of Nurse-Led Telemonitoring For Suicide Prevention, Finny Ngozi Rogers

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice project was a staff education initiative addressing a critical practice gap: clinical staff at a mental health facility lacked the practical knowledge to implement evidence-based telemonitoring protocols for suicide prevention, despite strong supporting research. High rates of suicide attempts and readmissions underscored the urgency for this intervention. The practice-focused question was: “Will a staff education program designed to educate healthcare providers on nurse-led telemonitoring protocols increase staff knowledge?” The purpose of this project was to develop, implement, and evaluate an educational program for providers to increase their knowledge on how a telemonitoring protocol can reduce …

The Ninth Chondroid Syringoma With Bone Formation: A Case Report, Mojan Deriss, Kelsey Ouyang, Parnian Alizadeh, Amir Qorbani, Voicu S. Ciobanu

Annual Research Symposium

This poster presents a rare case of chondroid syringoma with ossification, representing only the ninth reported instance of bone formation within this adnexal tumor. The report describes a slowly enlarging facial nodule in a 34-year-old male, detailing clinical presentation, surgical excision, and histopathologic findings. Microscopy revealed characteristic epithelial cords and tubules within a myxoid stroma, along with mature lamellar bone formation, confirming the diagnosis. The case expands the known morphologic spectrum of chondroid syringomas and highlights the importance of considering this entity in the differential diagnosis of benign facial masses, particularly when unusual features such as ossification are present.

Optimization Of A Kcc2 Small Molecule Agonist And The Development Of An In-Silico Model Of Intermolecular Dynamics For The Rational Design Of Therapeutics Against Opioid Use Disorder, William H.D. Ho, Alfred Amendolara, Kenyon Mitchell, Jaden Miner, Braxton Bingham, Andrew Payne

Annual Research Symposium

Roseman University Research Symposium

Wednesday, February 18, 2026 | 3:00 – 6:00 pm (local time)

Determinasi Minimum Dietary Diversity Pada Anak Usia 6-23 Bulan: Analisis Survei Kesehatan Indonesia 2023, Elfys Ferdynan, Besral Besral

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Keragaman pangan minimum atau minimum dietary diversity (MDD) merupakan indikator penting kualitas konsumsi pangan anak usia 6-23 bulan. Pemenuhan MDD berperan dalam mendukung pertumbuhan optimal dan pencegahan malnutrisi, termasuk stunting. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan pemenuhan MDD pada anak usia 6-23 bulan di Indonesia. Data yang digunakan adalah data Survei Kesehatan Indonesia 2023 dengan desain potong lintang. Subjek penelitian adalah 17.991 anak usia 6-23 bulan. Analisis yang dilakukan menggunakan regresi logistik biner dengan penyesuaian desain complex samples. Hasil penelitian menunjukkan bahwa faktor yang meningkatkan peluang pemenuhan MDD secara signifikan meliputi usia anak 12-23 bulan, …

Staff Education Project Staff Education On Medication Adherence, Blessing Nwoke

Walden Dissertations and Doctoral Studies

Medication adherence is a critical component of effective psychiatric treatment, yet staff understanding and consistent reinforcement of adherence strategies are often limited in outpatient behavioral health settings. This Doctor of Nursing Practice (DNP) project implemented a staff education initiative to improve knowledge and awareness of medication adherence using the ESPACOMP Medication Adherence Reporting Guideline (EMERGE) as the foundational framework. The program was conducted in an outpatient psychiatric facility and aimed to align staff knowledge with evidence-based standards for monitoring and supporting adherence. Educational sessions were delivered to clinical staff, incorporating key components of EMERGE to clarify terminology, enhance consistency in …

Hold Harmless For Whom? The Impact Of Covid Era Policies On School Funding, Teachers, And Students, Michah W. Rothbart, Samantha Cervantes, Amy Ellen Schwartz

Center for Policy Research

This study evaluates the fiscal and academic consequences of New York City’s hold harmless policy during COVID-19, which aimed to stabilize school expenditures amid unexpected enrollment declines by restoring schools’ funding up to initial levels. We examine how school racial composition predicts whether or when schools receive hold harmless “treatment” and assess the impact of hold harmless on financial resources, staffing, and student outcomes, exploring heterogeneity by timing of policy announcement. Although schools with higher White student shares were no more likely than those with higher Hispanic or Black shares to receive hold harmless funds, schools with higher Black shares …

Combination Lingual Compression And Maxillomandibular Fixation For Persistent Acquired Macroglossia: A Case Report, Emma De Ravin, Annie Moroco, Adam J. Luginbuhl

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

No abstract provided.

Evaluation Of The Consistency Of A Speech Verification System With Human Raters In Early Literacy Screening Assessments, Yaacov Petscher, Jennifer O'Sullivan, Hugh W. Catts, Ashley Edwards, Lisa Fitton Ph.D., Ccc-Slp

Faculty Publications

This study investigates the use of a speech verification system (SVS) technology, a form of automatic speech recognition (ASR), in the assessment of children's reading skills. Despite the growing integration of ASR systems in educational assessment, significant challenges persist, particularly due to the acoustic, pronunciation and dialectal variability inherent in children's speech. Our research evaluated the consistency between human rater (HR) and speech verification system (SVS) scores produced from SoapBox Labs across three linguistic tasks—phoneme blending, expressive vocabulary and word reading. Results reveal variability in agreement rates, with SVS showing lower consistency with human raters in phonologically complex tasks like …

Evaluation Of The Consistency Of A Speech Verification System With Human Raters In Early Literacy Screening Assessments, Yaacov Petscher, Jennifer O'Sullivan, Hugh W. Catts, Ashley Edwards, Lisa Fitton Ph.D., Ccc-Slp

Faculty Publications

This study investigates the use of a speech verification system (SVS) technology, a form of automatic speech recognition (ASR), in the assessment of children's reading skills. Despite the growing integration of ASR systems in educational assessment, significant challenges persist, particularly due to the acoustic, pronunciation and dialectal variability inherent in children's speech. Our research evaluated the consistency between human rater (HR) and speech verification system (SVS) scores produced from SoapBox Labs across three linguistic tasks—phoneme blending, expressive vocabulary and word reading. Results reveal variability in agreement rates, with SVS showing lower consistency with human raters in phonologically complex tasks like …

The Effect Of Increased Weight Loading On Body Weight Is Partly Dependent On Piezo1 In Osteoblast-Lineage Cells And Trka Signaling, Daniel Hägg, Lei Li, Alec T Beeve, Erica L Scheller, Jakob Bellman, Fredrik Anesten, Jovana Zlatkovic, Adrià Dalmau Gasull, Ferran Font-Gironès, Sofia Movérare-Skrtic, John-Olov Jansson, Claes Ohlsson

2020-Current year OA Pubs

UNLABELLED: Obesity is a complex disease driven by multiple factors, and a deeper understanding of its underlying mechanisms could enable the development of novel treatments. Based on our previous experimental studies, we have proposed a homeostatic mechanism regulating adiposity involving mechano-sensing of body weight by osteoblast-lineage cells in the lower extremities. However, the molecular mechanism underlying this proposed weight-sensing pathway remains to be elucidated. Recent studies have demonstrated that Piezo1-mediated mechano-sensing in osteoblast-lineage cells, as well as TrkA-dependent signaling, are essential for the normal bone anabolic response to high-intensity mechanical loading. We hypothesized that these pathways within bone may also …

Cell-Cell Communication As Underlying Principle Governing Color Pattern Formation In Teleost Fishes, Marleen Klann, Lila Solnica-Krezel, Et Al.

2020-Current year OA Pubs

The diverse pigmentation patterns of animals are crucial for predation avoidance and behavioral display. This diversity arises from interactions among distinct pigment cell types, yet mechanisms generating pattern variation across teleost fishes remain incompletely understood. In zebrafish, Turing models have been proposed to explain stripe patterns, but it is unclear if they apply to other fishes. Here, we investigate the Snowflake mutant of the anemonefish Amphiprion ocellaris, which displays enlarged white bars with irregular boundaries. Using genome-wide association mapping and targeted sequencing, we identify a missense mutation (E42K) in gja5b, encoding the gap junction protein Connexin 41.8. CRISPR/Cas9-mediated genome editing …

Management Of Acute Myeloid Leukemia: A Review, Chetan Jeurkar, Lana King, David Baek, Lindsay Wilde, Gina Keiffer, Margaret Kasner

Kimmel Cancer Center Faculty Papers

Background/Objectives: Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with historically poor outcomes, particularly among older adults and patients harboring high-risk molecular features. Advances in genomic profiling have enabled the development of targeted therapies, reshaping treatment algorithms beyond conventional cytarabine-anthracycline induction and hypomethylating agent-based regimens. This review summarizes current evidence and emerging therapeutic strategies across four evolving areas: menin inhibition, FLT3 inhibition, IDH inhibition and treatment approaches for TP53-mutated AML. Methods: We reviewed published clinical trials, preclinical studies, and ongoing clinical trials evaluating targeted therapies in AML. Emphasis was placed on agents with regulatory approval or substantial clinical development, …

Post-Operative Hernia Site Infections, Agatha Francesca Inga Gittens-Stay

Walden Dissertations and Doctoral Studies

This doctoral project was a clinical practice guideline (CPG) focused on the development of a perioperative guideline for patients undergoing various types of hernia repairs. Hernia repair is a common surgical procedure to address various types of hernias.. To assure continued compliance with nationally set benchmarks and minimize the rate of postoperative hernia infections, a systematic review of evidence-based practices (EBP) to foster infection prevention was initiated at a hospital in England. The practice-focused question used was: For patients who underwent hernia repair surgery, what evidence informs CPG recommendations on the type of material, surgical interventions, and nursing interventions to …

Exploring The Theoretical Foundation With Rupture And Delayed Rupture Experiments, Shi-Qing Wang, Junpeng Wang, Asal Y. Siavoshani, Cheng Liang

University Research

We carry out uniaxial continuous and step stretching of various cross-linked polymer networks to demonstrate how characteristics of rupture during continuous stretching and delayed rupture after step stretching can be used to probe the structure of the emergent kinetic activation theory of bond dissociation (KATBD) for elastomeric failure. Based on delayed rupture experiments, we show that the network lifetime tntw, taken as the incubation time tdel-rupt for delayed rupture, depends on temperature in an Arrhenius like manner and is exponentially sensitive to the degree of network stretching (depicted by the step-stretch ratio λss). Rupture at λb during continuous stretching for …

Comparative Safety, Efficacy, And Predictors Of Complete Occlusion Of Flow Diverter Devices In The Treatment Of Unruptured Distal Anterior Cerebral Artery Aneurysms, Hamza Adel Salim, Luca Scarcia, Frédéric Clarençon, Orabi Hajjeh, Motaz Daraghma, Davide Simonato, Yan-Lin Li, Eimad Shotar, Kevin Premat, Pascal Jabbour, Stavropoula Tjoumakaris, Michael R. Gooch, Marios Psychogios, Nikos Ntoulias, Peter Sporns, Ajit S. Puri, Jasmeet Singh, Anna Luisa Kuhn, Ameer E. Hassan, Oktay Algin, Markus A. Möhlenbruch, Sophia Hohenstatt, Riccardo Russo, Mauro Bergui, Oded Goren, Matthew J. Kole, Nourou Dine Adeniran Bankole, Richard Bibi, Gregoire Boulouis, Takeshi Morimoto, Fumihiro Sakakibara, Raoul Pop, Ciprian Juravle, Joanna W. K. Ho, Ãngel Ferrario, Virginia Pujol Lereis, Jared Cooper, Chirag D. Gandhi, Giancarlo Salsano, Lucio Castellan, Arturo Consoli, Alessandro Sgreccia, Eytan Raz, Charlotte Chung, Julien Burel, Chrysanthi Papagiannaki, Umair Rasheed, Khawaja Muhammad Baqir Hassan, Hong Tao, Zhe Ji, Riitta Rautio, Matias Sinisalo, Maria Ruggiero, Elvis Lafe, Valerio Da Ros, Luigi Bellini, Joseph Domenico Gabrieli, Francesco Causin, Michael R. Levitt, Kate Carroll, Zachary Abecassis, Antonio Armando Caragliano, Sergio Lucio Vinci, Guillaume Bellanger, Christophe Cognard, Gaultier Marnat, Lisa Saleille, Nicola Limbucci, Francesco Capasso, Mariangela Piano, Claudia Rollo, Alexis Guedon, Francesco Arpaia, Andrea Romi, Fortunato Di Caterino, Alessandra Biondi, Erwah Kalsoum, Mykola Vyval, Adrien Guenego, Than Nguyen, Mohamad Abdalkader, Thibault Agripnidis, Aman B. Patel, Vitor Mendes Pereira, Maurizio Fuschi, Alessandro Pedicelli, Vivek Yedavalli, Max Wintermark, Andrea M. Alexandre, Adam A. Dmytriw, Creta Investigators

Department of Neurosurgery Faculty Papers

BACKGROUND: Flow diverters (FDs) are increasingly used for cerebral aneurysms, including distal anterior cerebral artery (DACA) aneurysms, but comparative data between devices in this challenging location are limited.

OBJECTIVE: To compare the safety and efficacy of Pipeline, Silk Vista Baby (SVB), and FRED Jr. FDs for unruptured DACA aneurysms and identify predictors of complete occlusion.

METHODS: We retrospectively analyzed 166 patients treated with FDs at 39 centers in 14 countries (2018–2022) from the CRETA registry. Outcomes included aneurysm occlusion (O’Kelly–Marotta [OKM] scale), complications, retreatment, modified Rankin Scale (mRS) scores, and independent predictors of complete occlusion using multivariable Cox regression.

RESULTS: …

Staff Education To Prevent Falls Among Older Adults In Primary Care, Chioma Nwosu

Walden Dissertations and Doctoral Studies

Falls are a significant health concern for the elderly population and a major cause of injury and functional decline among older adults, yet fall prevention practices are inconsistently applied in primary care. The purpose of this project is to evaluate the impact of staff education on fall risk screening and prevention for adults aged 65 years and older using the CDC’s Stopping Elderly Accidents, Deaths, and Injuries (STEADI) framework. This project employs a pre–post quality improvement design in a primary care clinic. Clinical staff received education on STEADI-based fall risk assessment, documentation, and evidence-based interventions. Data were collected through chart …

Social, Political, And Economic Determinants For Hiv Prep Care Delivery Innovations, Joanne Senoga Brown

Walden Dissertations and Doctoral Studies

Pre-exposure prophylactic care delivery innovations (PCDI) are critical to the Ending the HIV Epidemic (EHE) initiative. While individual studies have examined isolated factors such as patient awareness, provider willingness to prescribe, and cost-effectiveness, few have synthesized these findings into a unified framework explaining how structural social, political, and economic determinants jointly influence PCDI. Prior literature remains fragmented, emphasizing behavioral or programmatic variables rather than systemic structures. This meta-analysis was done to examine how structural determinants independently and collectively influence PCDI across the 47 U.S. EHE jurisdictions. Guided by the consolidated framework for implementation research and Rogers’s diffusion of innovations theory, …