Medicine and Health Sciences Commons^™

Inflammatory And Immunological Basis Of Periodontal Diseases, Thomas Van Dyke Dds, Phd

Metro Denver Dental Society Articulator Magazine

This review examines periodontitis as a chronic immune-mediated inflammatory disease shaped by interactions between the host response and oral microbiome. It explores how immune cells, inflammatory mediators and impaired resolution pathways contribute to connective tissue destruction and alveolar bone loss, while also considering links between periodontal and systemic inflammation. The authors highlight emerging research that may support more precise diagnostic and immune-based treatment strategies.

Volume 32, Issue 3

Metro Denver Dental Society Articulator Magazine

The 3rd Quarter 2026 issue of the Articulator explores the evolving clinical, professional and personal challenges shaping dentistry today, from emerging aligner technology and periodontal science to leadership and professional well-being. Articles include:

• MDDS President Dr. J.R. Franco reflects on family history, justice, patient advocacy and the responsibility of dentists to create meaningful change through organized dentistry.
• Dr. Amisha Singh examines how service and achievement can become tied to professional identity, and encourages dental professionals to find purpose and worth beyond accomplishment.
• Ms. Laura Ramsey explores advances in clear aligner therapy, including digital workflows, artificial intelligence and 3D printing, while …

Aligner Technology Today:, Laura Ramsey

Metro Denver Dental Society Articulator Magazine

Clear aligner therapy continues to advance through digital scanning, AI, treatment-planning software and emerging 3D-printing technologies. This article explores how these innovations are improving efficiency and expanding treatment options while emphasizing that successful outcomes still depend on sound diagnosis, biomechanics and clinical judgment.

Preparing For The Next Big Thing: We’Ve Seen What Ai Can Do. Now, Get Ready For Cloning., Stuart L. Segelnick Dds, Ms

The New York State Dental Journal

Until recently, artificial intelligence was seen as science fiction. Now, it is interwoven into all aspects of our lives, including our dental practice. Cloning may be the next futuristic fantasy to permeate our consciousness. According to Leslie G. Biesecker, M.D., director and NIH Distinguished Investigator, Center for Precision Health Research, “Cloning, as it relates to genetics and genomics, involves using scientific methods to make identical, or virtually identical, copies of an organism, cell or DNA sequence.” As the cloning process and other bioengineering techniques advance, one can only wonder how and when they will impact the dental landscape.

A Systematic Review Of Recommendations For Asynchronous Teledentistry, Helen Chen D.D.S., Seeun Mo D.D.S., Rami Habib D.D.S., Hannah Kim D.D.S., Madusha Perera D.D.S., Courtney H. Chinn D.D.S., M.P.H.

The New York State Dental Journal

Background: COVID-19 renewed interest in teledentistry to improve access to oral healthcare. This review assessed recommendations for asynchronous teledentistry regarding image capturer, device, target population, capture protocol and diagnostic ability.

Methods: Five reviewers conducted a PRISMA guided search for eligible studies published from 2000–2023. Articles were independently evaluated using a four-point rubric.

Results: Sixteen articles were included, with a mean score of 5.38/15. The lowest score was for image capturer, and the highest for diagnosis of oral disease.

Conclusion: Limited evidence supports standardized protocols, underscoring the need for further research on best teledentistry practices.

Odontogenic Myxoma In Maxilla: A Case Report, Deepak Gupta, Ravinder Singh, Nazrana Maqbool B.D.S., Rakashree Chakraborty B.D.S., M.D.S.

The New York State Dental Journal

Odontogenic myxoma (OM) is a rare, benign but locally invasive intraosseous neoplasm. It is known to arise from the mesenchymal portion of the tooth germ. Although it is a slow-growing tumor, maxillary odontogenic myxomas can lead to increased morbidity caused by invasion into the maxillary sinus and middle cranial fossa. Further, it is also important to delineate the margins of OM to achieve a better treatment outcome. Here we present a case of a maxillary odontogenic myxoma in a 26-year-old female patient. The patient presented with swelling on the upper right side of the face. Computed tomography scan revealed a …

Udm Dean's Report - A Look At The Student Of Today As We Prepare Them For Tomorrow, Mert N. Aksu Dds, Jd, Mhsa, Cert. Dph

The Journal of the Michigan Dental Association

UDM Dental School Dean Mert N. Aksu discusses the profiles, expectations, and challenges of modern dental students, highlighting their collaborative nature, tech-savviness, and focus on wellness and work-life balance. The report outlines UDM's clinical curriculum enhancements, including systems-based biomedical integration, and extensive clinical practice labs. Aksu addresses the substantial 58% inflation-adjusted rise in educational debt since 2008 and updates on community service rotations (Corktown Clinic, Titans for Teeth), the implementation of the new Vermont Track for rural care, the adoption of AI radiographic analysis, and comprehensive student mental health support programs.

From The President - The Transformative Value Of Our Profession, Melanie E. Mayberry, Dds, Ms-Hcm

The Journal of the Michigan Dental Association

Melanie E. Mayberry, MDA President, reflects on the transformative value of dentistry on both patients and the personal lives of practitioners. The article emphasizes how the dental profession builds stronger communities through service, empathy, mentorship, and continuous learning. Highlighting student and patient resilience in the face of adversity, Mayberry draws inspiration from events like the Kalamazoo Mission of Mercy, where volunteers provided over one million dollars in free dental care. She encourages dentists of all generations to foster a community of belonging, embrace professional evolution, and appreciate the spiritual and personal rewards of their service.

Um Dean's Report - Meeting The Challenge Of Educating Dentists In A Constantly Evolving Profession, Jacques E. Nör

The Journal of the Michigan Dental Association

University of Michigan School of Dentistry Dean Jacques Nör highlights the school's historical legacy during its 150th anniversary and details recent academic, clinical, and research progress. Key developments include the establishment of the state-of-the-art Digital Dentistry Center for in-house digital workflows, a pediatric certificate program in Social Epidemiology funded by a $2.1 million federal grant, the transition to Epic electronic health records (integrated with MyChart), and the community-based collaborative care rotation program in Marquette. The report also highlights national faculty leadership roles and $24.1 million in research funding.

J Mich Dent Assoc Sept. 2026

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association delivers news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200-plus members. It remains the main publication reaching Michigan dentists and is available worldwide through ADA Commons.

The September 2026 (Volume 108, No. 9) issue of the Journal is published in print format to provide updates and insights for Michigan's oral health community and MDA members. Print editions occur every other month beginning with January.

This full compilation of the September 2026 Journal of the Michigan Dental Association features the deans' reports from the …

Closing Gaps In Urban Trauma Systems: Outcomes Of An Inner-City Community Emergency Department Multidisciplinary Trauma Protocol, Kory S. London, Alan Cherney, Sulabh Neupane, H. Alex Tomlinson, Joseph Cervone, Elaine Qian, Casey Fishman, Jennifer Davis, Sean Mcgann, Varsha Goswami, George Koenig, Frederick Randolph

Department of Emergency Medicine Faculty Papers

BACKGROUND: Non-trauma center (NTC) emergency departments (EDs) play regular but underappreciated roles in the management of severely injured patients, yet many lack formal protocols to guide care. We describe the implementation and outcomes of a structured trauma evaluation and transfer protocol at an urban NTC emergency department.

METHODS: A multidisciplinary trauma protocol was implemented on April 1, 2023, at an urban NTC, supported by a Level I trauma center, 2.5 miles apart. The study period ran from January 1, 2019, to June 30, 2025. Using pre-post study design, 62 patients treated prior to implementation were compared with 49 post-intervention patients. …

A National Study Of Tetanus Vaccine Knowledge, Receipt And Acceptance Among Emergency Department Patients, Francesco Sergi, Elisa Vaezazizi, Shaokui Ge, Christopher Alvarez, Jesus Torres, Brian Chinnock, Michael Gottlieb, Vijaya Arun Kumar, Kristin L. Rising, Efrat Kean, Stephanie Eucker, Robert M. Rodriguez

Department of Emergency Medicine Faculty Papers

OBJECTIVE: The Tetanus, Diphtheria, Pertussis (Tdap, "tetanus") vaccine is recommended for adults every 10 years. In a national sample of adult emergency department (ED) patients, we sought to determine (1) knowledge and up-to-date status of the tetanus vaccine; (2) reasons for nonreceipt of the vaccine; (3) vaccine acceptability if offered in the ED; and (4) reasons for nonacceptance in the ED if offered.

METHODS: This was a cross-sectional survey study among non-critically ill adults at 10 US EDs, asking questions about knowledge, receipt, and acceptability of the tetanus vaccine. Vaccine receipt was determined by self-report. Aggregate responses are reported as …

An Observational Study Of The Effect Of Concomitant Levetiracetam On Apixaban Concentrations In A Hospital Cohort, Chazmyn Riley, Kevin Lam, Cristina Micale, Lynda Thomson, Douglas F. Stickle, Walter K. Kraft

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Despite the lack of evidence of a mechanism-based drug interaction, some professional organizations have advised caution coadministering apixaban and levetiracetam. Eligible patients taking apixaban with or without levetiracetam for any indication for at least 72 h were screened from the electronic medical records. Plasma samples from 77 patients were retrieved from salvaged clinical blood collections. Apixaban minimum and maximum concentrations (Cmin and Cmax) were compared using descriptive statistics in R. While the median Cmin and Cmax appear to be marginally elevated, there were no apparent differences relative to apixaban alone. These findings suggest no apparent interaction of levetiracetam and support …

Prediction Model For Children With Anaphylaxis Who May Not Require Emergency Department Care: A Multicenter Retrospective Cohort Study., Timothy E. Dribin, David Schnadower, Hugh A. Sampson, Yin Zhang, Nanhua Zhang, Stephen B. Freedman, Mark I. Neuman, David C. Brousseau, Rakesh D. Mistry, Stephanie Boyd, Yonatan Wolnerman, Patrick S. Walsh, Craig Vander Wyst, Vandana Thapar, Jonathan Strutt, Geetanjali Srivastava, Nidhi V. Singh, Christopher J. Russo, Christian D. Pulcini, Thuy L. Ngo, Jo-Ann O. Nesiama, Matthew M. Moake, Ashley M. Metcalf, Tamar R. Lubell, Juhee Lee, Chari D. Larsen, Karen Y. Kwan, Curtis L. Knoles, Kajal Khanna, Julia F. Freeman, Justin R. Davis, Alicia Daggett, Joanna S. Cohen, Ari R. Cohen, Wee-Jhong Chua, Sri S. Chinta, Brittany Boswell, Kelly R. Bergmann, Paul L. Aronson, Kenneth A. Michelson

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: The 2023 US Anaphylaxis Practice Parameter indicated that some patients receiving epinephrine in the community might avoid emergency department (ED) visits; however, the criteria and safety of this approach remain unproven.

OBJECTIVE: To derive and validate a clinical prediction model for identifying children at risk of receiving epinephrine after arriving at the ED.

METHODS: We conducted a 31-center retrospective cohort study of children aged 6 months to less than 18 years who received 1 prehospital dose of epinephrine for allergic reactions between 2016 and 2019. The outcome was receipt of epinephrine after ED arrival. We used least absolute shrinkage …

Characteristics Of Individuals With Cerebral Palsy Across The Us., Bhooma R. Aravamuthan, Amy F. Bailes, Micah Baird, Kristie Bjornson, Ira Bowen, Angeline Bowman, Elizabeth R. Boyer, Rose N. Gelineau-Morel, Laurie Glader, Paul H. Gross, Stacey Hall, Edward A. Hurvitz, Michael Kruer, Thomas Larrew, Neena I. Marupudi, Patrick G. Mcphee, Stephen A. Nichols, Garey Noritz, Joyce Oleszek, Justin Ramsey, Jeffrey S. Raskin, Heather Riordan, Brandon G. Rocque, Manish N. Shah, Benjamin J. Shore, M Wade Shrader, David Spence, Charles B. Stevenson, Richard Stevenson, Sruthi P. Thomas, Joyce P. Trost, Stephen R. Wisniewski, Cerebral Palsy Research Network

Manuscripts, Articles, Book Chapters and Other Papers

This cross-sectional study examines how demographics and characteristics of individuals with cerebral palsy across the US associate with Gross Motor Function Classification System level and genetic etiology.

Bulletin Ninth District Ny September 2026

Bulletin of the Ninth District Dental Association

In the September 2026 issue, the reader will find the following feature articles:

• "2026 D. Austin Sniffen Medal of Honor Recipient" with "Past Medal of Honor Recipients"
• "ADA Commons: Connecting Dentists to Research, Publications and History"
• "The History of Communal Water Fluoridation and its Continued Safe and Efficacious Use Today"

Also included are your monthly President's Message, event updates, continuing education opportunities, membership news and classifieds.

Skin Carotenoid Scores Are A Valid Approximation Of Fruit And Vegetable Intake Among Adults With Obesity, Stephanie B Jilcott Pitts, Qiang Wu, Elizabeth Gates, Melissa N Laska, Andrew R Dinardo, Nancy E Moran

Children’s Nutrition Research Center Staff Publications

Skin carotenoid score (SCS) as measured using pressure-mediated reflection spectroscopy has been validated among adults with normal and overweight body mass index, with little validation research among adults with obesity. Therefore, the purpose of this exploratory study was to examine the validity of SCS as an approximation of fruit and vegetable intake among adults with obesity. We used samples from adults with obesity from three prior studies: The first study examined the validity of SCS among 213 adults, 34 with obesity; the second, examined sensitivity of SCS to a β-carotene-rich juice intervention among 162 adults, 14 with obesity; the third …

Prevalence Of Acute Periapical Abscesses In Cannabis Users, Ilan Rotstein D.D.S., Joseph Katz D.M.D.

The New York State Dental Journal

Background: Cannabis use and cannabis-related disorders have increased significantly worldwide. The aim of this study was to assess the prevalence of acute periapical abscesses (PAs) in cannabis users.

Methods: Data from 1,799,122 patients were analyzed and the odd ratio (OR) of acute PAs and their association with cannabis use were statistically compared.

Results: Patients using cannabis showed significantly more PAs than nonusers. The difference was statistically significant. Following adjustment for diabetes and smoking comorbidities, the statistical difference remained significant.

Conclusion: The risk for acute PAs is significantly higher in cannabis users as compared to nonusers.

Department Of Health Exerts Strong Control Over Cbct In Dental Offices: Regulations, Adopted Over Objection From Nysda, Take Effect Immediately., Lance Plunkett Jd, Llm

The New York State Dental Journal

On July 22, the New York State Department of Health finally adopted an entire set of new regulations covering all aspects of ionizing radiation. Contained in Article 16 of Title 10 of the Official Compilation of Codes, Rules and Regulations of the State of New York (10 NYCRR), the new regulations repealed and replaced the old Article 16. It is important to note that the new regulations are in effect only in counties outside of New York City. Dentists in New York City should still rely on guidance from the city Department of Mental Health and Hygiene. The regulations contain …

Becoming Instead Of Achieving, Amisha Singh Dds, Edd

Metro Denver Dental Society Articulator Magazine

MDDS, CO-Editor, Dr. Amisha Singh reflects on how service and achievement can become tied to identity in dentistry. She explores the pressure to be productive, useful and needed as well as the importance of finding worth beyond accomplishments.

Art, Advocacy & A Path Forward, J. R. Franco Dds

Metro Denver Dental Society Articulator Magazine

MDDS President J.R. Franco reflects on the personal experiences, family history and art that shaped his views on justice, patient advocacy and the role of dentists as healers. He connects evidence-based, prevention-focused care with the responsibility of dental professionals to advocate for patients and meaningful change through organized dentistry.

Lidocaine Combined With Low-Dose Esketamine For Movement-Evoked Pain After Hepatectomy: A Double-Blind Randomised Controlled Trial, Yan Xu, Li Zhou, Qianqian Tang, Feng Yu, Jingwen Wu, Siyu Yan, Min Cai, Jialu Wan, Yi Kang, Lajing Luowu, Mengmeng Zhou, Lulong Bo, Daniel I Sessler, Chunling Jiang

Faculty, Staff and Student Publications

Introduction: Pain following hepatectomy may delay recovery and increase opioid use. We tested the primary hypothesis that combining lidocaine and low-dose esketamine would reduce movement-evoked pain 24 h after hepatic resection. We also evaluated whether this approach reduced opioid consumption and improved quality of recovery.

Methods: Patients having elective hepatic resections were allocated randomly to receive lidocaine-esketamine or placebo from induction of anaesthesia until the end of surgery. After surgery, patients allocated to lidocaine-esketamine were given a continuous infusion of lidocaine with esketamine for 72 h. All patients received transversus abdominis plane blocks with ropivacaine 2 mg.kg-1 after induction of …

Trends In Antimicrobial Resistance Associated With Gastrointestinal Tract Infections In The Uae: A Comprehensive Retrospective Surveillance 13-Year (2010-2022) Study, Madikay Senghore, Jens Thomsen, Najiba M. Abdulrazzaq, Wei Chen, Eveline Kaambo, Stefan Weber, Fouzia Jabeen, Godfred Antony Menezes, Abiola Senok, Dean B. Everett, Carole Ayoub Moubareck

All Works

Background This study analyzes longitudinal trends in AMR among key bacterial pathogens causing GI infections across the United Arab Emirates (UAE), to inform future treatment policies and public health interventions. Methods We conducted a 13-year, nationwide, longitudinal surveillance study (2010-2022) using data from 341 public and private healthcare facilities and 45 diagnostic laboratories across the UAE. Pathogen identification and antimicrobial susceptibility testing followed WHO GLASS standards, supplemented by WHONET-integrated electronic medical records. Statistical analyses assessed trends in pathogen incidence, resistance patterns, geographic distribution, and associations with clinical outcomes. Findings Out of 15,593 laboratory-confirmed GI cases, the highest burden was observed …

The Influence Of Childhood Experiential History On U.S. Vice President Jd Vance’S Personality, Amelia Brower, Aubrey Immelman

Psychology Faculty Publications

This paper presents the results of a developmental causal analysis of the adult personality of U.S. vice president JD Vance, from the conceptual perspective of personologist Theodore Millon.

Psychodiagnostically relevant data relating to Vance’s personality were collected from biographical sources and media reports and synthesized into a personality profile using the Millon Inventory of Diagnostic Criteria (MIDC), which yields 34 normal and maladaptive personality classifications congruent with DSM-III-R, DSM-IV, and DSM-5-TR.

The findings of the personality assessment were previously reported in a separate paper. Vance’s primary personality patterns were found to be Dominant/controlling and Ambitious/confident, supplemented by …

A Word From The Writing Team (September 2026), Pam Walter, Mfa, Laura Deloretta, Phd

A Word From the Writing Team (Newsletter)

No abstract provided.

Hydroxyethyl Starch And Perioperative Complications: A Systematic Review And Meta-Analysis, Daniel I Sessler, Lorenzo Pradelli, Massimiliano Povero, Daniel Chappell, E Wang

Faculty, Staff and Student Publications

Background: Based on renal injury reported in critically ill and septic patients, the U.S. Food and Drug Administration issued a black box warning regarding hydroxyethyl starch (HES 130/0.4) use in 2013 and expanded the warning to surgical and trauma patients in 2021. Similarly, the European Medicines Agency initiated withdrawal of hydroxyethyl starch in 2022. This study was a new meta-analysis focused on renal injury designed to complement a 2021 meta-analysis of perioperative hydroxyethyl starch use, adding 45 trials and 6,895 patients. The focus was acute kidney injury and preoperative-to-postoperative change in creatinine concentration in surgical patients.

Methods: This study searched …

Patient-Centered Imaging In Dentistry, Erika Benavides Dds, Phd, Fabiana Naomi Soki, James R. Geist Dds, Ms, Angela M. Hoikka, Dds, Ms

The Journal of the Michigan Dental Association

This clinical feature discusses joint guidelines by the ADA and AAOMR for patient-centered dental radiography and cone-beam computed tomography (CBCT), emphasizing individual risk-based needs rather than routine schedules. It covers the principles of radiation safety: justification, optimization (ALARA/ALADA), and dose limitation. The article maps out specific imaging modalities recommended for caries, periodontal disease, endodontics, orthodontics, implants, and TMJ disorders. Additionally, it summarizes Michigan's administrative rules for X-ray installation shielding, equipment alignment, stable mechanical support, operator positioning, and the mandatory radiography training program requirements for dental assistants.

Mda Public Relations Grant Program Opens Applications For 2026 Cycle, Timothy Rath

The Journal of the Michigan Dental Association

The Michigan Dental Association is opening applications for its 2026 Public Relations Grant Program, offering individual grants of up to $5,000, with $30,000 in total funding, to support component dental societies. The program funds creative community-focused initiatives scheduled for 2027 that educate the public and promote oral health, excluding purely charitable clinical care. Eligible projects emphasize relationship-building and community engagement. Highlighted success stories from previous cycles include oral health kit distributions, youth-focused educational events, and the expansion of the 'Give Kids A Smile' exams and preventive care clinics across Michigan.

A Worldwide Cross-Sectional Survey Seeks The Current Global Practice Patterns On Perioperative Management In Elective Shoulder Replacement Surgery, Maciej Simon, Farhad Moola, Jennifer Coghlan, Osvandre Lech, Carlos Ramos, Njalalle Baraza, Hadrian Platzer, Simone Gantz, Andreas Seekamp, Babak Moradi

General Surgery, East Africa

Background Perioperative management in elective shoulder arthroplasty varies widely, with no universal consensus on best practices. This study aimed to characterize current global standards of perioperative care, including pre-operative, intraoperative, and post-operative management, among orthopedic surgeons performing elective shoulder replacement surgery, with the aim of contributing to a global standard of care.

Methods A comprehensive online questionnaire was designed and anonymously distributed to orthopedic societies on each continent. Participants were cross-sectionally surveyed with the goal of identifying current global pre-operative, intraoperative, and post-operative practices in patient care and discharge management.

Results Eighteen societies from 5 continents participated in the survey. …

Diffusion-Informed Joint Segmentation Enhances Detection Of Thalamic Atrophy In Parkinson’S Disease, Gozde Kizilates-Evin, Ani Kicik, Emel Erdogdu, Dilek Betul Saridede, Sevim Cengiz, Basar Bilgic, Hasmet A. Hanagasi, Esin Ozturk-Isik, Tamer Demiralp, Ali Bayram

All Works

The thalamus is a critical subcortical hub that relays sensorimotor information and regulates higher-order cognitive processes. Accurate delineation of thalamic nuclei is essential for elucidating disease mechanisms and tracking clinical progression. In this study, we compared two segmentation approaches implemented in FreeSurfer: the conventional structural method and a joint framework that integrates diffusion tensor imaging. Magnetic resonance imaging (MRI) data from 24 healthy controls (HC), 27 patients with cognitively normal Parkinson’s disease (PD-CN), and 33 Parkinson's disease patients with mild cognitive impairment (PD-MCI) were analyzed. Segmentation methods were compared in HC to assess their effect on volume estimates. Group comparisons …