Effect Of Different Packing Protocols On Fracture Resistance Of Maxillary Premolars Restored With Bioactive Composite, Hend Sayed Ahmed, Mohamed Haridy, Hoda Fouda, Alaa Elgembri

Dentistry

Abstract

Objectives: The aim of the present study was to verify effect of different packing protocols on fracture resistance of

maxillary premolar teeth with standardized mesioocclusodistal (MOD) preparations restored with bioactive composite.

Materials and Methods: Seventy sound maxillary premolar teeth with standardized MOD cavities were randomly

allocated to seven groups (n=10): G1 (control): sound teeth; G2: unrestored MOD preparation; G3: was filled by an

incremental technique with nanohybrid resin composite (Beautifil II LS, Shofu); G4: was filled in bulk with flowable

composite (Beautifil Bulk Flowable, Shofu); G5: bulk filled with nanohybrid composite (Beautifil Bulk, Shofu); G6: was

restored by increment …

Anticancer Effects Of A Captopril Montmorillonite Formulation In Oral Cancer Cells Through Apoptosis And Redox Modulation, Dalia Ghalwash, Nada Saleh, Hadeel Mousa, Shereen Raafat

Dentistry

Abstract Background Oral squamous cell carcinoma (OSCC) remains challenging due to the limited efficacy and toxicity of current therapies. This study investigates the anticancer potential of Captopril–Montmorillonite (CP–MMT) (nanoclay-based delivery system), a drug-repurposing approach in which Captopril is incorporated within MMT nanoclay layered silicate carrier. To our knowledge, this formulation has not been previously investigated in OSCC cell lines, demonstrating enhanced anticancer efficacy. The aim of the work was to compare the anticancer effects of CP–MMT formulation with free Captopril in OSCC cell lines, focusing on cytotoxicity, apoptosis, cell-cycle arrest, oxidative stress, and key molecular markers. Methods CP–MMT nanoclay-based formulation …

Clinical Feasibility Of An Artificial Intelligence- Assisted Digital Workflow For Full-Arch Implant Rehabilitation: A Multicenter Case Series, Dalia Ghalwash, Marco Tallarico, Mohamed El Ashry, Carlotta Cacciò, Mohamad Qaddomi

Dentistry

Fully digital workflows are increasingly used in implant prosthodontics; however, completely edentulous full-arch rehabilitations remain challenging because implant position transfer and passive framework fit are susceptible to cumulative scanning and registration errors. Clinical evidence on artificial intelligence (AI)-assisted completearch implant impression workflows remains limited. This multicenter case series aimed to describe the clinical feasibility of an AI-assisted digital workflow (SmartX) combined with extended scan bodies for all-on-X full-arch implant-supported rehabilitations. Ten completely edentulous patients rehabilitated with all-on-X implant-supported fullarch prostheses were included. Digital impressions were obtained using SmartFlag scan bodies and an AI-assisted SmartX workflow with an intraoral scanner. The …

Chia Seed Extract As A Potential Adjunct In The Management Of Oral Candidiasis: An In Vitro Study, Dalia Ghalwash, Rawda Sayed, Ahmed Ammar, Eman Khalil

Dentistry

ABSTRACT Background Oral candidiasis remains a common opportunistic fungal infection, with increasing interest in natural antifungal alternatives. This study aimed to evaluate the antifungal activity of Salvia hispanica (chia) seed extract against oral Candida albicans, compare its efficacy with nystatin, assess their combined effect, and investigate cytotoxicity on WI-38 human fibroblast cells. Methods Antifungal activity was evaluated using broth microdilution and agar well diffusion assays, with nystatin oral suspension used as a positive control. Cytotoxicity of chia seed extract was assessed on WI-38 human fibroblast cells using the MTT assay. Results Chia seed extract demonstrated notable antifungal activity, with a …

Prevalence And Oral Hygiene–Related Correlates Of Self-Reported Dentin Hypersensitivity Among Egyptian Adults: A Cross-Sectional Study, Dalia Ghalwash, Ahmed Hamdy, Ahmed Ammar, Shehad Wael, Alhassan Diab

Dentistry

Abstract

Background

Dentin hypersensitivity (DH) is a prevalent clinical condition characterized by pain arising from exposed dentin in response to external stimuli. Despite its clinical relevance, epidemiological data from Egypt and the Middle East remain limited. This study aimed to assess the prevalence, symptom characteristics, and oral hygiene-related correlates of self-reported dentin hypersensitivity among Egyptians adults.

Methods

A cross-sectional questionnaire-based study was conducted among 370 Egyptian adults recruited from multiple governorates between January and August 2025. Data was collected using a structured questionnaire that underwent expert review, pilot testing, and reliability assessment. Information regarding self-reported dentin hypersensitivity, triggering stimuli, oral …

Prevalence Of Oral Mucosal Lesions Among Smokers Based On Gender: A Bicentric Cross-Sectional Study In Egypt, Dalia Ghalwash, Fatheya Zahran

Dentistry

Abstract

Background

Smoking is a major risk factor for developing various types of oral mucosal lesions (OMLs), including benign and potentially malignant lesions. However, scarce data is available concerning gender differences regarding the prevalence of oral mucosal lesions in smokers worldwide. Accordingly, this study assesses the prevalence and types of OMLs among male smokers compared to female smokers in an Egyptian population.

Methods

This hospital-based cross-sectional study included 300 male and 300 female smokers. All participants underwent a thorough case history review and a comprehensive clinical examination.

Results

The overall prevalence of oral lesions was significantly higher in males (75%) …

Dentists’ Acceptance Of Artificial Intelligence-Assisted Decision Support For Oral Potentially Malignant Disorder Detection: A Structural Equation Modeling Study, Dalia Ghalwash

Dentistry

Abstract

Artificial intelligence (AI) may support early detection and clinical decision-making of oral potentially malignant disorders (OPMDs), but clinical implementation depends on dentists’ acceptance of AI-assisted clinical decision support. This study aimed to identify structural associations of AI acceptance among dentists using an extended Technology Acceptance Model (TAM). A cross-sectional survey was conducted among 500 dentists. Construct validity and reliability were assessed using confirmatory factor analysis. Hypothesized associations were evaluated using structural equation modeling with bootstrap mediation analysis. The extended TAM showed generally satisfactory measurement properties and good overall model fit. Attitude toward AI showed the strongest association with behavioral …

When Drug Repurposing Backfires: Antagonistic Effects Of Ivermectin On Cisplatin Therapy In Oral Cancer, Dalia Ghalwash, Rana Tantawy, Shereen Nader, Ayman Elgawish

Dentistry

Abstract

Background

Cisplatin (CIS) remains the gold standard chemotherapeutic agent for the management of oral cancer. However, its clinical efficacy is frequently limited by chemoresistance and dose-dependent toxicities. Ivermectin (IVM), a well-established antiparasitic agent with emerging anticancer properties, has been proposed as a potential adjuvant capable of enhancing the antitumor efficacy of CIS.

Methods

In vitro experiments were conducted on HN9 oral squamous cell carcinoma cells, while OEC normal epithelial cells served as control. The experimental evaluation comprised the MTT assay for cell viability, Annexin V/propidium iodide (PI) staining for apoptosis detection, cell cycle distribution analysis, quantitative real-time PCR (RT-qPCR) …

A Narrative Review Of The Central Neural Control Of Swallowing And Its Implications For Dysphagia Rehabilitation, Kuo-Chang Wei, Tyng-Guey Wang, Ming-Yen Hsiao

Rehabilitation Practice and Science

Swallowing is controlled by a distributed neural network spanning the brainstem central pattern generator, subcortical modulatory circuits, and cortical regions responsible for volitional planning and sensorimotor integration. Evidence from lesion studies, neuroimaging, and neurophysiology demonstrates that dysphagia arises from disruptions at different nodes of this network, producing lesion-specific impairment profiles rather than a uniform swallowing deficit. This network-based perspective has shifted rehabilitation from predominantly compensatory management toward mechanism-driven interventions aimed at restoring physiological function. Behavioral skill-training and resistance-based exercises harness motor learning and cortical plasticity, whereas neuromodulatory approaches—including repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), pharyngeal electrical …

Experience And Barriers In Pediatric Dysphagia Rehabilitation: A Quantitative Survey Study, François-Xavier Brajot, Ai-Ju Wu, Pao-Chuan Torng

Rehabilitation Practice and Science

Purpose: Despite an important need for health care services targeting pediatric dysphagia, there exist a number of barriers to doing so, including workforce competence. The current study surveyed practicing Speech-Language Pathologists to determine (1) the importance of pediatric dysphagia in their caseload, (2) the adequacy of existing educational resources, and (3) perceived barriers to providing quality care in Taiwan.

Methods: An anonymous survey was completed by Speech-Language Pathologists working in Taiwan. Responses were analyzed with respect to current work setting, experience, preparation, and perceived barriers.

Results: Survey results from 122 respondents indicated that the pediatric dysphagia caseload is unexpectedly low …

Bridging The Gap Between Function-Based And Iddsi Standards In Dysphagia Care, Chien-Hui Cheng

Rehabilitation Practice and Science

No abstract provided.

A Scoping Review Of Non-Instrumental Dysphagia Screening Tools: Building Flowcharts To Guide Tool Selection, Yu-Chun Chang, Ming-Jhuan Wang, Shu-Fen Siao, Yu-Juan Xu, Meng-Shan Wu, Tyng-Guey Wang, Cheryl Chia-Hui Chen

Rehabilitation Practice and Science

Selecting an appropriate non-instrumental dysphagia screening tool is a complex process. This scoping review aimed to identify dysphagia screening tools with established reliability and validity, and to develop administrator-based flowcharts to guide tool selection across different clinical populations. A scoping review was conducted using studies identified in CINAHL, Embase, PsycINFO, PubMed, and Web of Science. Our search was guided by five keywords: “dysphagia,” “deglutition,” “screening,” “test,” and “measure.” Original studies about the development and validation of non-instrumental dysphagia screening tools were selected. Six reviewers were involved in the review process, and at least two reviewers independently completed each step of …

Dysphagia And Rehabilitation In Patients With Parkinson’S Disease, Jong Mi Park, Seo Yeon Yoon

Rehabilitation Practice and Science

Dysphagia is one of the most clinically important complications of Parkinson's disease (PD). It impairs nutrition and quality of life and is closely linked to aspiration pneumonia, a leading cause of death in this population. It is often underrecognized, partly because subjective complaints underestimate the impairment found on objective testing, and partly because silent aspiration progresses without a protective cough. This review examines dysphagia in PD from a rehabilitation perspective, covering its pathophysiology, clinical features, assessment, and the evidence for rehabilitative interventions. Parkinsonian dysphagia arises from dopaminergic, non-dopaminergic, and peripheral mechanisms, and because it responds inconsistently to levodopa, rehabilitation has …

Social Support As An Effect Modifier Of The Assocation Between Drug-Use Related Stigma And History Of Substance Use During Pregnancy Among Women Who Use Unprescribed Opioids In New York City: A Cross-Sectional Study, Isabelle C. Lynch

Graduate Studies Theses and Dissertations 2026

Substance use and misuse among women who are pregnant is a growing public health concern in the United States. Overdose deaths are now a leading cause of death among pregnant and postpartum women, and neonatal abstinence syndrome rates have increased to 23 per 1000 births. A barrier addressing substance use among these women is social stigma, which in part is driven by punitive drug policies that criminalize substance use during pregnancy and societal gender roles and norms surrounding women’s substance use. Social support, including emotional, instrumental, and informational support, can serve to mitigate the negative impacts of stigma on health …