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Full-Text Articles in Medicine and Health Sciences

Leading The Way In Pediatric Oral Health Promotion, Denise C. Mckinney Jan 2026

Leading The Way In Pediatric Oral Health Promotion, Denise C. Mckinney

Dental Hygiene Faculty Publications

[Introduction] Dental hygienists promote oral health and provide preventive services to patients throughout their lifespan. The Commission on Dental Accreditation, Dental Hygiene Standards emphasize that graduates must be competent in providing dental hygiene care for all patient populations, including children.¹ In fact, promoting pediatric oral health begins prior to birth with the expectant mother and/or caregiver. Oral health care to include education is essential during pregnancy; specifically, around the prevention and treatment of dental caries for the mother and the unborn child.² In the U.S., from 2013-2016, roughly 30% of women aged 20-44 years had untreated dental caries.³ Expectant mothers …


Biological Dental Hygiene: Principles, Educational Pathways, And Clinical Practice Considerations, Tara Newcomb Jan 2026

Biological Dental Hygiene: Principles, Educational Pathways, And Clinical Practice Considerations, Tara Newcomb

Dental Hygiene Faculty Publications

Dental hygiene practice is rapidly evolving in response to emerging evidence on the oral–systemic health connection, advances in preventive technologies, and increased emphasis on individualized, minimally invasive care. A commitment to lifelong learning and continuing professional development is essential for maintaining clinical competence and integrating new scientific knowledge into practice. Biological dental hygiene has emerged as a complementary framework that emphasizes whole-body health, biocompatibility, reduction of toxic exposures, and prevention-centered care. This approach expands traditional dental hygiene practice by incorporating enhanced risk assessment, salivary diagnostics, targeted preventive strategies, as well as patient education focused on nutrition, inflammation reduction, and systemic …


Dental Professionalism In A Changing World: Challenges & Opportunities, Robert P. Iovino, Dds, Ma Dds, Ma Jan 2026

Dental Professionalism In A Changing World: Challenges & Opportunities, Robert P. Iovino, Dds, Ma Dds, Ma

Journal of the American College of Dentists

This manuscript examines the erosion of traditional dental professionalism amid rising educational costs, declining membership in professional associations, and the growing influence of corporate ownership and private equity in dentistry. Drawing perspectives from economics, sociology, philosophy, law, and ethics, it traces the historical development of professional licensure and its role in safeguarding clinical autonomy, ethical integrity, and public trust. The analysis highlights how deregulation and profit-driven practice models challenge the profession’s social contract. The manuscript argues that preserving strong civic institutions, restrictive licensure standards, and humanities-informed education is essential to sustaining dentistry as a learned profession rather than a commodified …


Lessons On Generative Artificial Intelligence From The American Association Of Dental Editors And Journalists (Aadej), Christopher J. Smiley Jan 2026

Lessons On Generative Artificial Intelligence From The American Association Of Dental Editors And Journalists (Aadej), Christopher J. Smiley

Journal of the American College of Dentists

The American Association of Dental Editors and Journalists (AADEJ) recently released "Guidance for Authors, Editors and Publishers on the Use of Generative AI". Developed by an 11-member stakeholder panel, this guidance paper serves a dual purpose: It provides practical strategies for mitigating the risks that generative artificial intelligence (GAI) poses to professional writing and explains how GAI creates these risks. Understanding both the underlying vulnerabilities of GAI and how to address them is critical for users at all levels, from authors and reviewers to editors, publishers, and general users, to maintain the validity and reliability of their written work. This …


How Dentists Can Remain Advisors Of Merit To Their Patients, Daniel L. Orr Ii, Dds, Ms (Anesth), Phd, Jd, Md, Facd (Nevada Section Chair) Jan 2026

How Dentists Can Remain Advisors Of Merit To Their Patients, Daniel L. Orr Ii, Dds, Ms (Anesth), Phd, Jd, Md, Facd (Nevada Section Chair)

Journal of the American College of Dentists

This article examines how members of the dental profession can sustain their longstanding reputation as trusted advisors amid declining public confidence in major institutions. Grounded in ethical principles, informed consent, and professional self-regulation, dentistry has historically ranked among the most trusted professions. The discussion explores challenges to credibility, including media scrutiny, concerns about anesthesia safety, controversial treatment hesitancy, and debates over community water fluoridation. Emphasizing the concept of the “advisor of merit,” the author argues that continued trust depends on truthful communication, transparency about risks, respect for patient autonomy, and freedom from conflicts of interest in clinical and public health …


From The Archives: Continued Competency Assessment: Its History And Role In The Health Professions Jan 2026

From The Archives: Continued Competency Assessment: Its History And Role In The Health Professions

Journal of the American College of Dentists

Each issue of the Journal of the American College of Dentists (JACD) features an archival article selected for its continued relevance to contemporary issues in dentistry. This article provides historical context and enduring insights that inform current discussions in the profession.


J Am Coll Dent 2026 92 4 Jan 2026

J Am Coll Dent 2026 92 4

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.


The Birth Of Standards For Leadership In Oral Healthcare, Sir Nairn H.F. Wilson Cbe Dsc(H.C.) Ddent(H.C.) Phd Msc Bds Fcgdent Fds Rcs Edin, Eng(Hon) & Rcps Glasg(Hon) Ffd Rcsi(Hon) Fcdshk(Hon) Fracds(Hon) Drd Fhea Facd Ficd Fadm Fpfa Frsm Fkc Jan 2026

The Birth Of Standards For Leadership In Oral Healthcare, Sir Nairn H.F. Wilson Cbe Dsc(H.C.) Ddent(H.C.) Phd Msc Bds Fcgdent Fds Rcs Edin, Eng(Hon) & Rcps Glasg(Hon) Ffd Rcsi(Hon) Fcdshk(Hon) Fracds(Hon) Drd Fhea Facd Ficd Fadm Fpfa Frsm Fkc

Journal of the American College of Dentists

The Editorial is a feature in each issue of the JACD. It includes commentary on issue content, relevant topics, or other items of interest to the fellowship.


Letters To The Editor, David Chambers Ed.M.,M.B.A., Ph.D., Facd, Christopher J. Smiley Dds Jan 2026

Letters To The Editor, David Chambers Ed.M.,M.B.A., Ph.D., Facd, Christopher J. Smiley Dds

Journal of the American College of Dentists

This section of the Journal of the American College of Dentists presents professional correspondence regarding previously published articles and issues relevant to dentistry, ethics, education, policy, and patient care. Letters to the editor provide readers an opportunity to offer scholarly critique, clarification, perspective, or additional insight, while author responses promote constructive academic dialogue and continued professional reflection.


Core Standards For Leadership In Oral Healthcare, Sir Nairn H.F. Wilson Cbe Dsc(H.C.) Ddent(H.C.) Phd Msc Bds Fcgdent Fds Rcs Edin, Eng(Hon) & Rcps Glasg(Hon) Ffd Rcsi(Hon) Fcdshk(Hon) Fracds(Hon) Drd Fhea Facd Ficd Fadm Fpfa Frsm Fkc Jan 2026

Core Standards For Leadership In Oral Healthcare, Sir Nairn H.F. Wilson Cbe Dsc(H.C.) Ddent(H.C.) Phd Msc Bds Fcgdent Fds Rcs Edin, Eng(Hon) & Rcps Glasg(Hon) Ffd Rcsi(Hon) Fcdshk(Hon) Fracds(Hon) Drd Fhea Facd Ficd Fadm Fpfa Frsm Fkc

Journal of the American College of Dentists

This article introduces the American College of Dentists’ core standards for leadership in oral healthcare, grounded in well-established ethical principles and in response to ever-increasing expectations for patient-first care. It is suggested that the new standards must be consistently upheld to maintain patient trust and professional credibility. Effective leadership, in contrast to management, improves patient engagement and outcomes, team performance, and resilience. The article calls for more leadership training in dentistry, beginning in dental schools, and highlights the need for effective leadership in oral healthcare to strengthen the profession’s standing and status.


Standards For Leadership In Oral Health Care. A Project Of The Board Of Regents Of The American College Of Dentists, Robert A. Faiella Dmd, Mmsc., Mba, Teresa A. Dolan Dds, Mph, Facd, N. Karl Haden Phd, Facd, Sreenivas Koka Dds, Ms, Phd, Mba, Mas, Facd, Sir Nairn H.F. Wilson Cbe Dsc(H.C.) Ddent(H.C.) Phd Msc Bds Fcgdent Fds Rcs Edin, Eng(Hon) & Rcps Glasg(Hon) Ffd Rcsi(Hon) Fcdshk(Hon) Fracds(Hon) Drd Fhea Facd Ficd Fadm Fpfa Frsm Fkc Jan 2026

Standards For Leadership In Oral Health Care. A Project Of The Board Of Regents Of The American College Of Dentists, Robert A. Faiella Dmd, Mmsc., Mba, Teresa A. Dolan Dds, Mph, Facd, N. Karl Haden Phd, Facd, Sreenivas Koka Dds, Ms, Phd, Mba, Mas, Facd, Sir Nairn H.F. Wilson Cbe Dsc(H.C.) Ddent(H.C.) Phd Msc Bds Fcgdent Fds Rcs Edin, Eng(Hon) & Rcps Glasg(Hon) Ffd Rcsi(Hon) Fcdshk(Hon) Fracds(Hon) Drd Fhea Facd Ficd Fadm Fpfa Frsm Fkc

Journal of the American College of Dentists

This section of the Journal of the American College of Dentists presents professional conference proceedings and/or published guidelines relevant to dentistry, ethics, education, leadership, policy, or clinical care. Conference proceedings may also include documents from affiliate organizations in dentistry.


Letters Of Support From Affiliate Organizations Jan 2026

Letters Of Support From Affiliate Organizations

Journal of the American College of Dentists

This section of the Journal of the American College of Dentists presents professional conference proceedings and/or published guidelines relevant to dentistry, ethics, education, leadership, policy, or clinical care. Conference proceedings may also include documents from affiliate organizations in dentistry.


Practicing Dentistry And The Piano: Reflections On Coaching, Feedback, And The Humanities In Dental Education, Sarah E. Grafton Dmd Jan 2026

Practicing Dentistry And The Piano: Reflections On Coaching, Feedback, And The Humanities In Dental Education, Sarah E. Grafton Dmd

Journal of the American College of Dentists

Dentistry is often described as both art and science, yet its pedagogy still leans heavily on technical instruction. Drawing on the author’s personal experience as a lifelong piano student, this paper explores the parallels between learning a musical instrument and developing clinical skills in dental education. Both domains require the integration of mind and hand, repeated practice, and feedback that transform mistakes into growth. Piano training illustrates that mastery emerges not from innate talent but from deliberate practice and the willingness to accept critique. This orientation provides a framework for understanding dental education as coaching rather than didactic instruction. Dental …


Humanities And The Moral Vision Of Dentistry, Toni M. Roucka Rn, Dds, Ma, Facd Jan 2026

Humanities And The Moral Vision Of Dentistry, Toni M. Roucka Rn, Dds, Ma, Facd

Journal of the American College of Dentists

The Editorial is a feature in each issue of the JACD. It includes commentary on issue content, relevant topics, or other items of interest to the fellowship.


Empathy And Human-Centered Leadership In Community Health Center Dental Clinics, Pamela S. Alston Dds, Mpp, Facd Jan 2026

Empathy And Human-Centered Leadership In Community Health Center Dental Clinics, Pamela S. Alston Dds, Mpp, Facd

Journal of the American College of Dentists

A person-centered approach, with empathy toward patients, can improve satisfaction among both patients and dental health professionals. A dental director with a human-centered leadership style can improve the well-being of oral health team members. This article describes the role that empathy, a core value of humanism and professionalism, plays in accomplishing these improvements in community health center dental clinics. This article also describes the risks of empathy, as experienced by the author in her role as a dental director and practitioner, as well as documented in the literature. It further focuses on dental directors’ human-centered approaches to supporting oral health …


The History Of Dr. Suess And European Dentists From The Past: Relevant Lessons In Bioethics For Today, Howard A. Israel Dds, Facd Jan 2026

The History Of Dr. Suess And European Dentists From The Past: Relevant Lessons In Bioethics For Today, Howard A. Israel Dds, Facd

Journal of the American College of Dentists

The works of the author-illustrator Dr. Seuss evoke images of children’s books with moral themes, such as Yertle the Turtle and Horton Hears a Who. The life story of another Dr. Suess has remained relatively unknown. Walter Suess was an extremely talented dentist and musician in Austria. Brilliant and courageous, he became a victim of a morally depraved authoritarian regime and the absence of biomedical ethics during the reign of the Third Reich. The serendipitous discovery of the true story of Dr. Seuss and European dentists from this era offers lessons in bioethics relevant to today.


The Personal, Professional, And Practice: Integrating Health Humanities Into Dental Education, Margie Hodges Shaw Jd, Ma, Phd, Michael Yunker Dds, Nicholas Mercado Drph, Ms Jan 2026

The Personal, Professional, And Practice: Integrating Health Humanities Into Dental Education, Margie Hodges Shaw Jd, Ma, Phd, Michael Yunker Dds, Nicholas Mercado Drph, Ms

Journal of the American College of Dentists

Dentistry’s evolution as a profession reflects both scientific progress and enduring tensions between commercial and service-oriented models of care. Despite long-standing commitments to ethical education, dental training continues to privilege technical mastery over professional identity formation, leaving some future practitioners underprepared for the ethical and relational complexities of clinical practice. This paper situates these challenges within the historical separation of dentistry and medicine and argues that integrating the health humanities into dental education can strengthen professional identity formation and clinical ethics competency. Using a case study, we demonstrate how biases, professional obligations, and patient trust intersect in practice. We introduce …


Healthcare Provider Perspectives On A Clinical Decision Tool To Support Individualized Exercise Prescriptions And Discussions For Breast Cancer Survivors, Jinani Jayasekera, Oliver W. A. Wilson, Kaitlyn M. Wojcik, Eleanor M. Kerr, Rachelle Brick, David Berrigan, Jennifer Yeong-Shin Sheng, Takeo Fujii, Kathleen Thomas, Henri K. Parson, Padma Sheila Rajagopal, Richard L. Street Jr. Jan 2026

Healthcare Provider Perspectives On A Clinical Decision Tool To Support Individualized Exercise Prescriptions And Discussions For Breast Cancer Survivors, Jinani Jayasekera, Oliver W. A. Wilson, Kaitlyn M. Wojcik, Eleanor M. Kerr, Rachelle Brick, David Berrigan, Jennifer Yeong-Shin Sheng, Takeo Fujii, Kathleen Thomas, Henri K. Parson, Padma Sheila Rajagopal, Richard L. Street Jr.

Department of Medicine Faculty Publications

Purpose: We evaluated healthcare providers' current knowledge, practices, and perspectives on a novel clinical decision tool (beta-version) to facilitate individualized exercise prescriptions and discussions in clinical settings.

Methods: We recruited healthcare providers who had treated or provided care to breast cancer survivors aged >= 35-years in the past 12 months. The participants were presented with a tool to provide individualized exercise recommendations considering women's individual, clinical, and contextual characteristics. Validated and reliable pre-existing instruments were used to survey providers' current knowledge, practices regarding exercise discussions, and perspectives on the beta-version (paper-draft) of the novel tool.

Results: The sample consisted of …


Proceeding Of The 31st Annual Orthopaedic Symposium June 19, 2026, David Komatsu Jan 2026

Proceeding Of The 31st Annual Orthopaedic Symposium June 19, 2026, David Komatsu

Stony Brook Orthopaedic and Musculoskeletal Journal

Proceeding of the 31st Annual

Orthopaedic Symposium

June 19, 2026


Barriers To Mental Healthcare In Rural Agricultural Communities, Monica Salonga Jan 2026

Barriers To Mental Healthcare In Rural Agricultural Communities, Monica Salonga

Research Honors

Mental health diagnoses have become increasingly concerning in the United States (US). In 2024, 60 million adults in the United States experienced a mental illness, and over 14 million adults stated they had suicidal thoughts (Reinert et al., 2025). The Center for Disease Control (CDC) reports around 4,000 suicide-related deaths in the United States every year (CDC, 2025). One population that suffers from disproportionate rates of suicide is farmers and farm families. Farmers are ranked #4 in the United States regarding suicide rates (Miller & Rudolphi, 2022). Between 2003 and 2018, there were 1,935 suicide-related deaths committed by farmers (Miller …


Reply To: Malik Mmud On Early And Sustained Improvements In Sense Of Smell With Tezepelumab Treatment In Patients With Chronic Rhinosinusitis With Nasal Polyps (Waypoint), Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon Jan 2026

Reply To: Malik Mmud On Early And Sustained Improvements In Sense Of Smell With Tezepelumab Treatment In Patients With Chronic Rhinosinusitis With Nasal Polyps (Waypoint), Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon

Department of Otolaryngology (ENT) Faculty Publications

[Introduction] To the Editor:

We thank Professor MMUD Malik [1] for his interest in our recent publication describing the improvements in loss of smell symptoms with tezepelumab versus placebo in patients with uncontrolled chronic rhinosinusitis with nasal polyps in the WAYPOINT trial (NCT04851964) [2]. We appreciate Professor Malik's comments on the language used to describe the findings and the specific analyses presented as well as his note regarding the consistent improvements in sense of smell observed with tezepelumab treatment versus placebo, demonstrated by large effect sizes across three instruments.


The Epidemiology Of Catastrophic Head And Neck Injuries In High School And College Non-Football Sports: A 4-Decade Review, Courtney M. Meyer, Kristen L. Kucera, Samantha E. Scarneo-Miller, Zachary K. Winkelmann, Susan W. Yeargin Jan 2026

The Epidemiology Of Catastrophic Head And Neck Injuries In High School And College Non-Football Sports: A 4-Decade Review, Courtney M. Meyer, Kristen L. Kucera, Samantha E. Scarneo-Miller, Zachary K. Winkelmann, Susan W. Yeargin

Rehabilitation Sciences Faculty Publications

Background:

Catastrophic head and neck injuries (CHNIs) in sport are rare but can have disabling or fatal outcomes. Prior studies have focused on football, equipment-laden sports, or different injury severities, not CHNI in nonfootball sports.

Purpose:

To describe the epidemiology of CHNI across levels (high school vs collegiate) in nonfootball sports and evaluate differences in injury rates (IRs) by sport, sex, and decade.

Study Design

Descriptive epidemiological study.

Methods:

This study utilized 40 academic years (1982-1983 to 2021-2022) of surveillance data from the National Center for Catastrophic Sports Injury Research. Descriptive statistics summarized athlete, event, and injury characteristics. IRs were …


Stability Of Salivary Microrna Measures Across An Ncaa Division I Football Season: Implications For Microrna As A Biomarker Of Concussion, Thomas R. Campbell, Martina Zamponi, Delaney Leathers, Julie Cavallario, Jessica C. Martinez, Peter A. Mollica Jan 2026

Stability Of Salivary Microrna Measures Across An Ncaa Division I Football Season: Implications For Microrna As A Biomarker Of Concussion, Thomas R. Campbell, Martina Zamponi, Delaney Leathers, Julie Cavallario, Jessica C. Martinez, Peter A. Mollica

Rehabilitation Sciences Faculty Publications

Background

Clinicians often face challenges in concussion care due to a heavy reliance on subjective patient input. Recently, research has sought objective biomarkers, like salivary microRNAs, to improve concussion management. However, significant limitations hinder the use of microRNAs as a diagnostic tool, including the cumulative effects of a contact sport season. A better understanding of the response to a contact sport season would help researchers and clinicians interpret expression changes at the time of injury in the context of seasonal variation. in Therefore, this study investigated the reliability of previously identified salivary microRNA targets across one contact sport season.

Methods …


Rare Manifestation Of Scapular Cutaneous Larva Migrans Infection Among Sand Porters In Warm Climate: A Case Report, Prio Hangudi Sampurno, Tri Wisesa Soetisna Jan 2026

Rare Manifestation Of Scapular Cutaneous Larva Migrans Infection Among Sand Porters In Warm Climate: A Case Report, Prio Hangudi Sampurno, Tri Wisesa Soetisna

Occupational and Environmental Medicine Journal of Indonesia

Background Cutaneous larva migrans is a serpiginous helminthic infection common among certain occupations dealing with contaminated soil especially in warm climate. Most common predilections include the feet, legs, and buttocks with only a fraction of cases found on the trunk and upper extremities.

Case Presentation A rare scapular cutaneous larva migrans manifestation on a thirty-six years old sand porter with high occupational exposure was described. Physical examination revealed progressive pruritic and warm rash in a serpiginous pattern on the left shoulder.

Results Diagnosis was established based on characteristic serpiginous rash physical findings supported by history of contact. This case needed …


Incident Of Sensorineural Hearing Disorder In Toll Road Workers Exposed To Noise And Lead, Fitria Rimadhanty Setyaningtyas, Muhammad Ilyas, Dewi Yunia Fitriani, Suryo Wibowo Jan 2026

Incident Of Sensorineural Hearing Disorder In Toll Road Workers Exposed To Noise And Lead, Fitria Rimadhanty Setyaningtyas, Muhammad Ilyas, Dewi Yunia Fitriani, Suryo Wibowo

Occupational and Environmental Medicine Journal of Indonesia

Background Toll road workers are exposed to traffic noise and lead, both of which may increase the risk of sensorineural hearing loss (SNHL). This study aimed to examine the association between noise and lead exposure and the occurrence of SNHL among toll road workers.

Methods A cross-sectional study was conducted using secondary data derived from medical check-up records of 1,445 toll road workers in 2022. Study variables included age, sex, length of employment, past medical history, smoking status, job position, blood lead levels and SNHL incidence. Descriptive analyses were performed, followed by bivariate analysis using the chi square test and …


Fatigue Assessment And Workplace Decision-Making: A Scoping Review, Tamio Papilika, Rony Catur Wibowo, Famelia Famelia Jan 2026

Fatigue Assessment And Workplace Decision-Making: A Scoping Review, Tamio Papilika, Rony Catur Wibowo, Famelia Famelia

Occupational and Environmental Medicine Journal of Indonesia

Background Fatigue is a recognized contributor to impaired performance and increased occupational risk in safety-critical industries. Although various assessment tools are available, their real-world implementation and role in operational decision-making remain unclear.

Methods This scoping review mapped fatigue assessment methods in workplace settings and evaluated their application in operational contexts. A systematic search of PubMed and Google Scholar identified 693 records, of which 21 studies met the inclusion criteria for real-world occupational settings.

Results All included studies utilized combined subjective and objective fatigue assessment approaches; however, this finding should be interpreted in light of the search strategy. Administrative applications were …


Acute Correction Of Acquired Genu Valgum Secondary To Post-Traumatic Growth Arrest At The Time Of Distal Femur Fracture., Josiah Wolf, Nicholas Pelz, Adam Mansour, Christopher Iobst, Allen Kadado Jan 2026

Acute Correction Of Acquired Genu Valgum Secondary To Post-Traumatic Growth Arrest At The Time Of Distal Femur Fracture., Josiah Wolf, Nicholas Pelz, Adam Mansour, Christopher Iobst, Allen Kadado

Surgery Articles

A 14-year-old male patient sustained a distal femur fracture after a ground-level fall. His history was notable for severe acquired genu valgum secondary to a childhood lawnmower accident, which had required multiple limb salvage procedures including a Syme amputation and soft-tissue skin grafting. Acute correction of the limb deformity was performed concurrently with fracture fixation using a retrograde intramedullary nail and poller blocking screws. Retrograde intramedullary nailing represents a viable treatment option for simultaneous acute correction of acquired genu valgum and stabilization of distal femur fractures.


Transvascular Endobronchial Ultrasound-Guided Transbronchial Needle Aspirations (Ebus-Tbna) To Confirm Urothelial Carcinoma Metastasis To The Pulmonary Artery, Kyle Admire, Stephen Gegick Jan 2026

Transvascular Endobronchial Ultrasound-Guided Transbronchial Needle Aspirations (Ebus-Tbna) To Confirm Urothelial Carcinoma Metastasis To The Pulmonary Artery, Kyle Admire, Stephen Gegick

Department of Medicine Faculty Publications

Tumours within the pulmonary arteries provide a diagnostic challenge due to their similar appearance to pulmonary emboli. Often, the decision to sample is multidisciplinary and the best approach to take is often unknown. Here we describe a case of urothelial carcinoma which metastasised to the mediastinum with evidence of tumour burden within the pulmonary artery. Sampling of this by endovascular and thoracoscopic means was unsuccessful; however, we were able to provide a diagnosis using direct visualization with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). This report is the first of a central pulmonary artery tumour caused by urothelial carcinoma biopsied by …


Donor-Derived Cell-Free Dna In Antibody-Mediated Rejection: An Analysis Of The Surveillance Heartcare Outcomes Registry, Paul J. Kim, Amit H. Alam, Jeffrey J. Teuteberg, Kiran K. Khush, Sean P. Pinney, Richard K. Cheng, Amin Yehya, Jeremy Kobulnik, Kevin M. Pinney, Kris A. Oreschak, Christopher R. Ensor Pharmd, Steven Fan, Marcus A. Urey, Palak Shah, Shelley A. Hall Jan 2026

Donor-Derived Cell-Free Dna In Antibody-Mediated Rejection: An Analysis Of The Surveillance Heartcare Outcomes Registry, Paul J. Kim, Amit H. Alam, Jeffrey J. Teuteberg, Kiran K. Khush, Sean P. Pinney, Richard K. Cheng, Amin Yehya, Jeremy Kobulnik, Kevin M. Pinney, Kris A. Oreschak, Christopher R. Ensor Pharmd, Steven Fan, Marcus A. Urey, Palak Shah, Shelley A. Hall

Department of Medicine Faculty Publications

Background

Donor-derived cell-free DNA (dd-cfDNA) has emerged as a biomarker for antibody-mediated rejection (AMR), but its performance characteristics have not been evaluated in a large contemporary heart transplant population.

Objectives

The study aimed to characterize the incidence and timing of biopsy-proven AMR and evaluate the performance characteristics of dd-cfDNA for AMR.

Methods

The authors included 2,240 subjects from the SHORE (Surveillance HeartCare Outcomes Registry) registry transplanted between 2017 and 2022 with verified biopsy, dd-cfDNA, echocardiographic, and donor-specific antibody (DSA) data. They evaluated the performance characteristics of dd-cfDNA for AMR and the incidence of AMR in different clinical contexts.

Results

AMR …


Assessment Of Skin In Patients With Systematic Sclerosis Using High-Frequency Ultrasound And Shear Wave Elastography: A Comparative Study With Histology, Molecular, And Clinical Parameters, Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi Jan 2026

Assessment Of Skin In Patients With Systematic Sclerosis Using High-Frequency Ultrasound And Shear Wave Elastography: A Comparative Study With Histology, Molecular, And Clinical Parameters, Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi

Department of Medicine Faculty Publications

Objective: Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large-scale comparison of US-based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US-based skin assessments for their face validity (differentiation between involved SSc and healthy control [HC] skin), construct validity (comparison to modified Rodnan skin score [mRSS]), and criterion validity (comparison to histologic and gene expression fibrosis markers).

Methods: Twenty HCs and 52 patients with SSc underwent clinical and US assessment followed by a forearm skin biopsy. Predefined areas were assessed on the finger, hand, …