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Articles 13501 - 13530 of 14783
Full-Text Articles in Medicine and Health Sciences
An Intuitionistic Fuzzy Hypergraph Model Enhanced By Forest-Of-Walks Dynamics For Medical Image Segmentation, Brinthaguru Thangaraj, Karthick Palanisamy
An Intuitionistic Fuzzy Hypergraph Model Enhanced By Forest-Of-Walks Dynamics For Medical Image Segmentation, Brinthaguru Thangaraj, Karthick Palanisamy
Mansoura Engineering Journal
The process of accurately segmenting Urolithiasis and pulmonary nodules from medical images presents significant difficulties because of three main factors which include nonuniform intensity distribution and the presence of weak object borders and the uncertainty caused by anatomical structure overlaps. The study introduces F-Zinhger as a solution to these problems through its application of the Forest of Walks technology. The method uses superpixels as fundamental elements which form a multi-scale hypergraph that establishes hyperedges through three criteria: intensity similarity, spatial proximity, and Z-intuitionistic fuzzy hesitation to capture complex contextual connections. The system incorporates a random walk-based label propagation system. The …
Effet Sur La Qualité De L'Air Et La Santé Des Travailleurs Et Travailleuses Dans Les Logements Alternatifs Des Poules Pondeuses, Magali-Wen St-Germain, Valérie Létourneau, Marc Veillette, Perrine Cruaud, Candice Lemaille, Kim Robitaille, Éloïse Denis, Araceli Dalila Larios Martínez, Sébastien Fournel, Stéphane Godbout, Geneviève Dion, Andréanne Côté, Laurianne Gratton, Martine Boulianne, Caroline Duchaine
Effet Sur La Qualité De L'Air Et La Santé Des Travailleurs Et Travailleuses Dans Les Logements Alternatifs Des Poules Pondeuses, Magali-Wen St-Germain, Valérie Létourneau, Marc Veillette, Perrine Cruaud, Candice Lemaille, Kim Robitaille, Éloïse Denis, Araceli Dalila Larios Martínez, Sébastien Fournel, Stéphane Godbout, Geneviève Dion, Andréanne Côté, Laurianne Gratton, Martine Boulianne, Caroline Duchaine
Rapports de recherche scientifique
Les oeufs de poules en liberté et les oeufs provenant « d’élevage confort » sont maintenant des produits communs dans les marchés alimentaires du Québec. Cette nouvelle variété de produits est le résultat de l’évolution des pratiques afin de concilier le bien-être des poules pondeuses et les besoins de l’industrie. En effet, d’ici l’année 2036, les logements conventionnels pour poules pondeuses (logements grillagés pour des petits groupes de poules) seront graduellement remplacés par des logements alternatifs. Les logements alternatifs pour poules pondeuses regroupent les colonies enrichies et les logements sans cages (sur plancher ou en volière). Ils ont en commun …
Évaluation De L’Exposition Aux Microorganismes Et Appréciation Du Risque Sanitaire Des Chauffeurs De Camion Et Des Éboueurs Attitrés Au Transport Des Matières Résiduelles Et Des Déchets, Geneviève Marchand, Loïc Wingert, Maximilien Debia, Carla Viegas, Susana Viegas, Liliana Caetano, Magdalena Twarużek, Nancy Lacombe, François Gouin, Delphine Lanoie, Isabelle Valois, Robert Kosicki, Marta Dias, Ewelina Soszczyńska, Julien Trépanier, Tam Nguyen, Fabiola Salambanga, Noémie Gervais
Évaluation De L’Exposition Aux Microorganismes Et Appréciation Du Risque Sanitaire Des Chauffeurs De Camion Et Des Éboueurs Attitrés Au Transport Des Matières Résiduelles Et Des Déchets, Geneviève Marchand, Loïc Wingert, Maximilien Debia, Carla Viegas, Susana Viegas, Liliana Caetano, Magdalena Twarużek, Nancy Lacombe, François Gouin, Delphine Lanoie, Isabelle Valois, Robert Kosicki, Marta Dias, Ewelina Soszczyńska, Julien Trépanier, Tam Nguyen, Fabiola Salambanga, Noémie Gervais
Rapports de recherche scientifique
La gestion des déchets au Québec repose sur la collecte sélective pour revaloriser les matières résiduelles et réduire l’enfouissement. Les travailleurs du secteur sont exposés aux bioaérosols contenant microorganismes et allergènes. Les risques sanitaires sont influencés par la nature des matières manipulées et les méthodes de travail employées. La manutention des déchets a déjà été mise en lien avec des inflammations respiratoires, des troubles digestifs, et des syndromes liés aux poussières organiques toxiques. L’objectif du projet visait à évaluer l’exposition des travailleurs aux microorganismes et d’en apprécier les risques pour la santé.
Dans le cadre de ce projet, 28 camions …
Allier Les Technologies Numériques À La Prévention Des Lésions Professionnelles Pour Intervenir Auprès D'Une Population Faiblement Scolarisée Se Préparant À L'Emploi, Marie Laberge, Aurélie Tondoux, Myriam Bérubé, Céline Chatigny, Denys Denis
Allier Les Technologies Numériques À La Prévention Des Lésions Professionnelles Pour Intervenir Auprès D'Une Population Faiblement Scolarisée Se Préparant À L'Emploi, Marie Laberge, Aurélie Tondoux, Myriam Bérubé, Céline Chatigny, Denys Denis
Rapports de recherche scientifique
Ce rapport présente les résultats d’un projet de recherche visant à améliorer la santé et la sécurité au travail (SST) des élèves du Parcours de formation axée sur l’emploi (PFAE) au Québec. Ce programme accueille chaque année entre 11 000 et 13 000 élèves de 15 ans à 21 ans qui éprouvent des difficultés scolaires et risquent de quitter l’école sans diplôme. Le PFAE offre des stages d’apprentissage en milieu de travail pour des métiers semi-spécialisés, couvrant un large éventail de secteurs d’activités. Les élèves du PFAE sont particulièrement vulnérables en matière de SST puisqu’ils sont très jeunes et ont …
Intentional Reflection Of Student Experiences During Graduate Nursing Education, Laura Gray Phd, Steven Busby, Aine O'Connor, Julie Honey
Intentional Reflection Of Student Experiences During Graduate Nursing Education, Laura Gray Phd, Steven Busby, Aine O'Connor, Julie Honey
Funded Scholarship
Background: Nurse practitioners can help fill needs for primary care providers but first must successfully transition from registered nurse through graduate education, which presents challenges and opportunities for growth.
Purpose: The purpose of this study was to describe experiences of nurses during the first semester of graduate school. Methods: Reflections of 23 students were analyzed by nursing faculty using qualitative descriptive methods.
Results: Five main concepts were identified by students: Academic performance, Challenges, Emotions, Linking coursework to future role, and Support.
Conclusion: Reflective journaling may help students process and adapt to challenges of graduate school.
Molar-Incisor Hypomineralization: Diagnosis, Management, And Treatment, Giovana Anovazzi Medeiros Dds, Msc, Phd, Bahareh Enghiad Dmd, James R. Boynton Dds, Ms
Molar-Incisor Hypomineralization: Diagnosis, Management, And Treatment, Giovana Anovazzi Medeiros Dds, Msc, Phd, Bahareh Enghiad Dmd, James R. Boynton Dds, Ms
The Journal of the Michigan Dental Association
Molar Incisor Hypomineralization (MIH) is a qualitative developmental enamel defect affecting at least one permanent first molar. Characterized by high porosity and reduced mineral content, MIH leads to hypersensitivity, post-eruptive breakdown, and increased caries susceptibility. The etiology is multifactorial, typically occurring between birth and four years of age. Management depends on severity, ranging from topical fluorides and sealants for mild cases to stainless-steel crowns or extractions for severe instances. Because porous enamel facilitates bacterial penetration and pulpal inflammation, achieving effective local anesthesia is often difficult, necessitating individualized behavioral management and early intervention to preserve tooth structure.
(Not So) Common Courtesy, Michael Saba
(Not So) Common Courtesy, Michael Saba
Journal of the Macomb Dental Society
This article features a monthly column from the Macomb Dental Society's editor, Dr. Michael Saba. This month Dr. Saba shares a story that reminds readers to both be courteous and to enforce it early with patients.
Amyloidoma Of The Palate, Philip Bacigalupo D.D.S., Nora Odingo B.D.S., D.M.D., M.P.H.
Amyloidoma Of The Palate, Philip Bacigalupo D.D.S., Nora Odingo B.D.S., D.M.D., M.P.H.
The New York State Dental Journal
There have been 17 reported cases of isolated amyloid deposition (amyloidoma) of the hard palate (Table 1). We present an 18th case, with a review of the literature on amyloidosis. Systemic conditions, such as multiple myeloma, must be ruled out when amyloid deposition is present. However, localized amyloidoma of the palate is rare, and there are few cases reported in the literature.
Going Green: Can We Save Teeth And The Planet?, Stuart Segelnick Dds, Ms
Going Green: Can We Save Teeth And The Planet?, Stuart Segelnick Dds, Ms
The New York State Dental Journal
You might not think you have a role to play in combatting climate change, but dentists can make a difference by reducing plastics in their offices.
No Need To Travel The Road To Licensure Renewal Alone, Brenda Turner
No Need To Travel The Road To Licensure Renewal Alone, Brenda Turner
The New York State Dental Journal
NYSDA has the Tool to Support Dentists Every Step of the Way
Ips Subperiosteal Implant For The Maxilla And Mandible, Tal Sastow, Ian Mark, Edward Woodbine, Jared Miller, Erik D. Gilroy, Harry Dym
Ips Subperiosteal Implant For The Maxilla And Mandible, Tal Sastow, Ian Mark, Edward Woodbine, Jared Miller, Erik D. Gilroy, Harry Dym
The New York State Dental Journal
This two-case report presents the use of the Individual Patient Solutions (IPS) Implants® Preprosthetic system in two patients with distinct clinical needs.
Case #1 involves a 69-year-old male with significant unilateral maxillary bone loss and a residual oroantral communication (OAC) following the failure of both conventional implants and sinus lift procedures. Case #2 involves a patient with a severely atrophic, edentulous mandible. These cases present two distinct and challenging clinical scenarios where both traditional endosseous and zygomatic implants were not feasible. Both cases were successfully managed with a custom-designed IPS subperiosteal implant.
This innovative approach involves a rigidly fixated, stable …
Network Leasing Or Dental Insurance Fleecing?, Stuart Segelnick Dds, Ms
Network Leasing Or Dental Insurance Fleecing?, Stuart Segelnick Dds, Ms
The New York State Dental Journal
Let’s put an end to dental insurance billing surprises.
Oral Myeloid Sarcoma: Rare Presentation Of Refractory Acute Myeloid Leukemia With Adverse Molecular Profile, Lauren A. Musial, Naomi Ramer Dds
Oral Myeloid Sarcoma: Rare Presentation Of Refractory Acute Myeloid Leukemia With Adverse Molecular Profile, Lauren A. Musial, Naomi Ramer Dds
The New York State Dental Journal
Myeloid sarcoma is a rare extramedullary presentation of acute myeloid leukemia and is especially uncommon in the oral cavity. The presence of myeloid sarcoma may be the initial manifestation of an underlying hematolymphoid disorder or may indicate relapsing disease. We report a case of a 48-year-old male with refractory acute myeloid leukemia who presented with a painful, yellow, plaque-like ulceration on the buccal mucosa. Incisional biopsy demonstrated ulcerated squamous mucosa with a dense infiltrate of large, atypical immunoblastic cells admixed with a prominent population of morphologically atypical eosinophils. These findings were consistent with myeloid sarcoma in the context of the …
N Y State Dent J June 2026
The New York State Dental Journal
In the June/July 2026 issue, the reader will find the following feature articles:
- HIV Screenings in Dental Settings: Feasibility, Challenges and Opportunities
- Oral Myeloid Sarcoma
- Generational Differences in Dentistry and Dental Practice
This issue includes regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.
Life Membership Status Awarded To 61 Members, Mda Membership Department Staff
Life Membership Status Awarded To 61 Members, Mda Membership Department Staff
The Journal of the Michigan Dental Association
The Michigan Dental Association (MDA) recently awarded life membership to 61 members for their long-term commitment, requiring either 30 consecutive or 40 total years of membership. This status includes active life members, who still practice, and retired life members, who are exempt from dues. These individuals contribute to the profession through mentoring, teaching, and legislative outreach, as well as volunteering in local clinics. The article lists new life members across various Michigan districts, including Central, Detroit, and West Michigan. This recognition honors their decades of dedication to organized dentistry and their ongoing impact on both the association and their local …
What About Our Teen-Age Patients?, Michelle C. Dziurgot
What About Our Teen-Age Patients?, Michelle C. Dziurgot
The Journal of the Michigan Dental Association
This editorial advocates for "mentally treating" teenage patients, specifically those around 14 years of age, as adults. By respecting their concerns and allowing age-appropriate decisions, clinicians can enhance a teen's dental IQ and self-esteem. This approach fosters confidence, communication, and independence, encouraging patients to take accountability for their treatment outcomes. Respectful dialogue leads to better compliance with home care, such as using rotary brushes or wearing retainers. Ultimately, treating teenagers with empathy and valuing their opinions helps them blossom into responsible adults while building lasting professional bonds.
Pediatric Dentists’ Best Practices When Treating Children With Autism Spectrum Disorders: A National Survey, Samita Gumber Bds, Mds, James R. Boynton Dds, Ms, Larry B. Salzmann Dds, Rodney J. Vergotine Bchd, Msc(Dent), Faapd, Fiadt, Fabpd, Ficd, Marita R. Inglehart Dipl. Psych., Dr. Phil., Dr. Phil. Habil
Pediatric Dentists’ Best Practices When Treating Children With Autism Spectrum Disorders: A National Survey, Samita Gumber Bds, Mds, James R. Boynton Dds, Ms, Larry B. Salzmann Dds, Rodney J. Vergotine Bchd, Msc(Dent), Faapd, Fiadt, Fabpd, Ficd, Marita R. Inglehart Dipl. Psych., Dr. Phil., Dr. Phil. Habil
The Journal of the Michigan Dental Association
This national survey evaluates how pediatric dentists manage patients with Autism Spectrum Disorder (ASD). While most practitioners collect data on oral hygiene and verbal communication, fewer assess social interaction or sensitivity-related characteristics. The study suggests using supplemental intake forms to plan appointments based on individual needs and functioning levels. Key accommodations reported include behavior guidance, modified appointment times, and operatory adjustments. Results indicate that increased professional experience with ASD correlates with more comprehensive data collection and a higher perceived value of that information. Ultimately, partnering with parents is vital for creating successful dental encounters for children with ASD.
Association Of N-Terminal Pro-Brain Natriuretic Peptide With Ckd Progression In The Ckd In Children Study., Alexander Kula, David K. Prince, Joseph T. Flynn, Susan L. Furth, Bradley A. Warady, Tamara Isakova, Derek Ng, Jeese Seegmiller, Rob Christenson, Nisha Bansal
Association Of N-Terminal Pro-Brain Natriuretic Peptide With Ckd Progression In The Ckd In Children Study., Alexander Kula, David K. Prince, Joseph T. Flynn, Susan L. Furth, Bradley A. Warady, Tamara Isakova, Derek Ng, Jeese Seegmiller, Rob Christenson, Nisha Bansal
Manuscripts, Articles, Book Chapters and Other Papers
No abstract provided.
Food Insecurity In Older Adults With Cancer, Page Laborde
Food Insecurity In Older Adults With Cancer, Page Laborde
Senior Honors Theses and Projects
Food insecurity is a growing concern among older adults and is associated with poor health outcomes, particularly among those with cancer. Community-based programs such as Meals on Wheels may help address these challenges, but their role in supporting older adults with cancer is not well understood. This study examined the association between recent non-skin cancer diagnosis and food insecurity, as well as relationships with Meals on Wheels participation. A cross-sectional analysis was conducted using secondary data from Rounds 9 through 14 of the National Health and Aging Trends Study (NHATS), a nationally representative sample of U.S. adults aged 65 and …
The Performance Of Machine Learning Algorithms In Predicting Under-Five Anaemia In Tanzania, Henry Ofori Duah, Derrick Nyantakyi Owusu, Godwin G. Duah, Paul Shidende
The Performance Of Machine Learning Algorithms In Predicting Under-Five Anaemia In Tanzania, Henry Ofori Duah, Derrick Nyantakyi Owusu, Godwin G. Duah, Paul Shidende
College of Nursing Faculty Research and Publications
Aim
Anaemia in children under five remains a major public health concern, contributing significantly to global child morbidity and mortality. With the rise of machine learning (ML), novel opportunities exist to model and predict anaemia more effectively. This study aimed to evaluate and compare the performance of five ML algorithms in predicting anaemia among under-five children in Tanzania.
Methods
We conducted a secondary data analysis using the 2017 Tanzania Malaria Indicator Survey (TMICS). The dataset (n = 5906) was randomly split into training (70%) and test (30%) sets. Five ML algorithms, Linear Discriminant Analysis (LDA), Logistic Regression, Random Forest (RF), …
Comparing Us Medicare Coverage Options As A Contributing Mechanism To Sticking Or Switching To An Insurance Plan, Lisa M. Grabert, Brian J. Miller, Kathryn L. Wagner
Comparing Us Medicare Coverage Options As A Contributing Mechanism To Sticking Or Switching To An Insurance Plan, Lisa M. Grabert, Brian J. Miller, Kathryn L. Wagner
College of Nursing Faculty Research and Publications
Background
In 2025, the US Medicare program is expected to spend over $1.1 trillion taxpayer dollars. A growing trend in the US Medicare program is more beneficiaries electing a private insurer, referred to as Medicare Advantage (MA), to manage their care. Since 2023, a slight majority of Medicare beneficiaries have elected to enroll in MA, yet little is understood about the mechanisms that drive beneficiaries toward their choices.
Methods
Our objective was to examine the association between comparing coverage options and ‘switching’ or ‘sticking’ with Fee-for-Service (FFS) Medicare or Medicare Advantage (MA). We conducted a panel study, using data from …
From The Goodness Of Our Hearts: A Scoping Review Of Qualitative Literature On Altruism As A Reward Mechanism For Nursing, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Emily Horner, Norah L. Johnson
From The Goodness Of Our Hearts: A Scoping Review Of Qualitative Literature On Altruism As A Reward Mechanism For Nursing, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Emily Horner, Norah L. Johnson
College of Nursing Faculty Research and Publications
Introduction
Altruism, the desire to help others, is a common motivation for choosing a career in nursing. Improved understanding of the role of altruism as a reward or motivation for currently-practicing nurses may inform future interventions to improve effort-reward balance among practicing nurses. Therefore, the purpose of this study was to collect, examine, and present literature on how altruism has been described as a reward mechanism or motivation for engaging in professional nursing.
Methods
This scoping review of literature used the Arksey & O’Malley method, PRISMA-ScR reporting checklist, and Rayyan review management platform. PubMed, Web of Science, and CINAHL were …
An Educational Intervention On Mutual Goal Setting For Hospital Nurses: A Mixed-Methods Study, Teresa Jerofke-Owen, Kristi Opper, Joseph Beiler, Maharaj Singh
An Educational Intervention On Mutual Goal Setting For Hospital Nurses: A Mixed-Methods Study, Teresa Jerofke-Owen, Kristi Opper, Joseph Beiler, Maharaj Singh
College of Nursing Faculty Research and Publications
Background:
Including patients in mutual goal setting is one mechanism to personalize care delivery and improve patient outcomes.
Objective:
The purpose of this study was to examine the impact of a nurse educational intervention about mutual goal setting on nurse engagement and self-efficacy for goal setting and the nurse/patient experience of goal setting.
Methods:
During this explanatory, sequential mixed-methods study, nurse engagement in goal setting and goal quality was assessed through chart audits 1-month pre-intervention (n = 173) and 1 and 3-months (n = 144, n = 137) post-intervention. Nurse self-efficacy was measured with the Appraisal Inventory Tool. Patient experience …
Politics Of A Silent Pandemic: Antimicrobial Resistance And State Capacity In India And Nigeria, Mia Kelly
Politics Of A Silent Pandemic: Antimicrobial Resistance And State Capacity In India And Nigeria, Mia Kelly
CMC Senior Theses
Antimicrobial Resistance (AMR) has emerged as one of the most pressing yet widely underestimated health threats of the 21st century; this thesis explores the potentially devastating global impact of this “silent pandemic”, exposing how deeply health outcomes depend on political choices, regulatory capacity, and economic constraints. Although the danger of spreading drug-resistant pathogens is now widely acknowledged in both the scientific and political communities, states differ in their abilities to contain the issue, with low- and middle-income countries facing the greatest obstacles to national action plan implementation. This thesis investigates these disparities through a comparison of India and Nigeria, two …
Racial Bias In Collateral Report Of Adhd Symptom Endorsement, Teresa Mejia
Racial Bias In Collateral Report Of Adhd Symptom Endorsement, Teresa Mejia
Electronic Theses & Dissertations (2024 - present)
Attention-Deficit/Hyperactivity Disorder (ADHD) is the most frequently diagnosed mental health condition among children in the United States. However, prevalence rates in the diagnosis and treatment of ADHD are unequal across populations. Specifically, the literature has demonstrated consistent variability in symptom endorsements and diagnosis dependent on a child’s demographic factors (i.e., race, gender, age). A diagnosis of ADHD requires that the diagnostic criteria be met in at least two aspects of a child's life, usually the school and home environments. As such, teacher reports are commonly used in the assessment of ADHD for children and adolescents. Given the challenges in obtaining …
Pillpetz: A Smarter Way To Encourage Medication Adherence In Children, John H. Begley
Pillpetz: A Smarter Way To Encourage Medication Adherence In Children, John H. Begley
CMC Senior Theses
Medication adherence is usually framed as a problem of patient behavior, but this thesis argues that it is equally a problem of design. Children who take daily medication face barriers that adults often do not: developing executive function, dependence on caregivers, shifting school and home routines, privacy concerns, and stigma around being perceived as different. The standard prescription bottle, by contrast, was designed primarily for dispensing efficiency, safety, and accidental ingestion prevention—not for sustained daily use by a developing child.
This thesis proposes PillPetz, a smart pill case and digital companion that uses routine, play, dose confirmation, and caregiver-connected support …
Modulating Oran Nitrate-Reducing Bacteria To Enhance Nitric Oxide Bioavailability As A Therapeutic Target For Atherosclerosis, Donovan C. Davidson
Modulating Oran Nitrate-Reducing Bacteria To Enhance Nitric Oxide Bioavailability As A Therapeutic Target For Atherosclerosis, Donovan C. Davidson
CMC Senior Theses
Atherosclerosis remains the primary driver of global cardiovascular disease, yet clinical interventions are largely restricted to high-cost, invasive procedures only after it has reached a critical stage. Recent research has identified a connection between the oral microbiome and vascular health via the enterosalivary nitrate-nitrite-nitic oxide (NO) pathway. Oral nitrate-reducing bacteria (ONRB) drive the synthesization of NO by reducing dietary nitrate into nitrite, which is then converted into bioavailable NO. NO is a potent vasodilator that maintains endothelial health by suppressing inflammation through inhibiting the expression of adhesion molecules VCAM-1 and ICAM-1. However, this pathway is easily compromised by dysbiotic oral …
Not Biological, But Built: Structural And Metabolic Pathways Driving Black Maternal Health Disparities In The United States, Alexandra I. Umegboh
Not Biological, But Built: Structural And Metabolic Pathways Driving Black Maternal Health Disparities In The United States, Alexandra I. Umegboh
CMC Senior Theses
Black infants in the United States are more than twice as likely to die before their first birthday than white infants, a disparity often attributed to genetics, behavior, or individual health choices. However, this idea is challenged by a key contradiction: African immigrant women consistently experience better birth outcomes than U.S.-born Black women despite being similarly racialized. This thesis investigates the origins of this reproductive advantage and the factors contributing to its decline over time. By drawing on epidemiological data, metabolic health research, and literature on African diasporic healing traditions, it argues that the “healthy immigrant effect” is not biological, …
Intermittent High-Fat, High-Sugar Access During Adolescence Drives Binge-Restriction Feeding And Reduced Weight Gain In A Food Unpredictability Model, Calvin G. Miller
Intermittent High-Fat, High-Sugar Access During Adolescence Drives Binge-Restriction Feeding And Reduced Weight Gain In A Food Unpredictability Model, Calvin G. Miller
CMC Senior Theses
Food insecurity affects nearly 48 million Americans and 318 million people worldwide, with very low food security disrupting normal eating habits through “feast-or-famine” episodes characterized by cycles of food overconsumption followed by restriction. This dietary pattern alters dopamine signaling within the mesocorticolimbic system — brain circuitry intimately linked to reward processing. This system includes the ventral tegmental area (VTA) and prefrontal cortex (PFC). Overstimulation can be promoted through sporadic high-fat, high-sugar diet (HFHSD) exposure, promoting dopamine neuron architecture alterations and binge-eating behavior. Adolescence represents a vulnerable window, as mesocorticolimbic dopamine projections undergo maturation during this period. Though evidence links food …
The Effects Of Vitamin K On Neuronal Ferroptosis, Chelsey P. Eighmey
The Effects Of Vitamin K On Neuronal Ferroptosis, Chelsey P. Eighmey
Electronic Theses & Dissertations (2024 - present)
Dementia is a crippling illness affecting millions worldwide causing significant public health burdens with long-term care. The lack of treatment options results in many years of suffering for affected individuals and their loved ones who often become primary caretakers. Decades of study have focused on treating dementia with little-to-no success, so an emphasis is needed on attempting to prevent disease progression altogether. This research explored vitamin K as a potential strategy for prevention of dementia onset or progression through the mechanism of suppressing ferroptosis. Ferroptosis is a type of cell death suggested to contribute to the hallmark traits of Alzheimer’s …