Medicine and Health Sciences Commons^™

The Relationship Between Prenatal Stressful Life Events And Breastfeeding Initiation Among Mississippi Mothers, Candon Garbo, Katie C. Hall, Disha Jhaveri, Jung Hye S. Lee, Deanna Howington, Mina Qobadi, Mary Wesley

Journal of Public Health in the Deep South

Background: Early initiation of breastfeeding increases the likelihood of exclusive breastfeeding, which can be linked to improving both the mother’s and infant’s health. However, breastfeeding rates in Mississippi continue to be one of the lowest in the United States, with infant mortality and morbidity rates at the highest. Purpose: This study aims to explore the impact SLEs may have on initiating breastfeeding, as research is limited. Methods: Analyzed data from 2016 to 2021 Pregnancy Risk Assessment and Monitoring System (PRAMS) was used to determine a correlation between life stressor experiences during pregnancy and initiation of exclusive breastfeeding with a sample …

Healthy Moms/Healthy Babies Of Mississippi Initial Provider Engagement And Student Feedback Loop Project, Corban Jackson Mph, Jillian Harper-Peavy Lmsw, Imh-E, Starica Harper, Vernesia Wilson Phd, Mph

Journal of Public Health in the Deep South

Background Between 2017 and 2022, 83% of maternal deaths in Mississippi were preventable. Unfortunately, there is a persistent shortage of OB-GYNs in Mississippi, feeding the rise of maternal care deserts and the lapse in collaboration between providers and state maternal health organizations. Purpose Healthy Moms/Healthy Babies of Mississippi, a care management program for high-risk mothers and infants, has partnered with the Mississippi Alliance for Innovation on Maternal Health initiative (AIM) to improve maternal health outcomes through building healthcare networks with existing providers. Methods 33 medical students from the University of Mississippi Medical Center School of Medicine and William Carey University …

A Retrospective Descriptive Study Of Maternal Morbidity Based On Mississippi Poison Control Center Data, Laura Lee S. Beneke, Zariad Saran, Mallory Pullman, Jenna Davis, David Vearrier

Journal of Public Health in the Deep South

Maternal morbidity and mortality remain significant public health concerns in the United States, but particularly in Mississippi, which has one of the highest maternal mortality rates in the country. This study analyzes data from the Mississippi Poison Control Center (MPCC) from January 2020 through December 2024 to assess trends in exposures among pregnant women. A total of 168 cases were identified. Exposures were categorized as unintentional, intentional, adverse reactions, or unknown, with unintentional exposures (47.6%) being the most common, often due to medication misuse. Intentional exposures, often linked to suspected self harm (31.5% of cases), represented 39.9% of the total. …

More Than Words: How Communication Shapes Maternal Healthcare Experiences In Mississippi, Brittney Clayborn, Traci Hayes

Journal of Public Health in the Deep South

Effective communication between healthcare providers and pregnant individuals is a critical factor in shaping maternal healthcare experiences. This study explores the role of provider-patient communication in prenatal and postnatal care among a group of Mississippi mothers, highlighting how communication influences trust, decision-making, and overall satisfaction with care. Using qualitative data collected through in-depth interviews, this case study examines both positive and negative communication experiences, identifying key barriers such as dismissiveness, lack of transparency, and rushed interactions. Findings suggest that when providers engage in clear, compassionate, and culturally competent communication, patients feel more empowered and supported in their care. Conversely, poor …

Maternal Mortality In Mississippi: Enough Is Enough, Daniel P. Edney Md, Facp, Fsam

Journal of Public Health in the Deep South

No abstract provided.

State Of Maternal Health, Jaleen Sims Md, Mph, Facog

Journal of Public Health in the Deep South

No abstract provided.

Measuring Nursing Student’S Performance, Attitude And Psychological Impact Of Different Evaluation Approaches In Simulation Education At Arab American University- Palestine, Mohammad Asia, Maysa Kassabry

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

This study aimed to compare the competency and psychological impact of using the objective structured clinical examination (OSCE) to the traditional evaluation methods (TEM) in evaluating cardiology skills among nursing simulation students. Thirty-two students were initially assessed using TEM, and one week later using the OSCE. Scores of the student competency were compared using paired sample t-tests, while semi-structured interviews were used to expand on qualitative measures. Students' mean scores were significantly higher in using OSCE than in TEM (p< 0.001). Students' attitudes and perceptions of both approaches showed favorable attitudes towards OSCE on most of the items. The qualitative data showed that students with lower GPAs and utilizing the OSCE approach experienced higher anxiety. The psychological impact of evaluation approaches requires additional investigation.

The Effect Of The Proposed Training Program Using Body Resistance Exercises (Trx) On The Level Of Some Physical And Skill Abilities Of Female Gymnasts In Jerusalem, Hala Jaber, Ahmad Sharaf

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

The aim of this study is to identify the effect of the proposed training program using body resistance exercises (TRX) on the level of some physical and skill abilities of female gymnasts in the governorates of Jerusalem. The study was conducted on a sample of (30) gymnasts at the Rosary Sisters School, they were divided into two groups, the experimental group and its members (15) and the control group and its members (15), after ensuring the homogeneity and equivalence of the sample. The control group was subjected to the traditional program, and the experimental group was subjected to the proposed …

Improved Perceived Health Status Among Persons Practicing Yoga For Pain Management, Mary Kovoor

NYMC Student Theses and Dissertations

Purpose of the Study: The purpose of this research was to examine the relationship between yoga practice and perceived health status, and to evaluate the benefits of yoga as a pain management strategy for low-income individuals.

Methods: An observational cross-sectional study was conducted and analyzed using 2022 National Health Interview Survey (NHIS) data. Logistic regression analyses examined whether the practice of yoga affected perceived health status, and whether low-income individuals were more likely to practice yoga for pain management.

Results: Analyses revealed that individuals who practiced yoga were 1.7 times more likely to report their health status positively than those …

Quality Improvement Project Enhancing Communication Perceptions Among Nursing Staff In The Operating Room, Denis Awu

Doctor of Nursing Practice Projects

Effective communication in the operating room (OR) is crucial for ensuring patient safety and optimal surgical outcomes. Communication breakdowns among surgical teams are a leading cause of sentinel events and procedural errors. This quality improvement (QI) project aimed to enhance communication perception among OR nursing staff through a structured training program focused on verbal, non-verbal, active listening, and communication under pressure. Grounded in Social Cognitive Theory and implemented using both Kotter’s 8-Step Change Model and the Plan-Do-Study-Act (PDSA) cycle, the intervention included interactive workshops and simulation exercises delivered over a six-week period. A total of 50 registered nurses participated in …

Next-Generation Biomaterials For Load-Bearing Tissue Interfaces: Sensor-Integrated Scaffolds And Mechanoadaptive Constructs For Skeletal Regeneration, Rahul Kumar, Kyle Sporn, Pranay Prabhakar, Phani Paladugu, Akshay Khanna, Alex Ngo, Chirag Gowda, Ethan Waisberg, Ram Jagadeesan, Nasif Zaman, Alireza Tavakkoli

SKMC Student Presentations and Publications

Advancements in load-bearing tissue repair increasingly demand biomaterials that not only support structural integrity but also interact dynamically with the physiological environment. This review examines the latest progress in smart biomaterials designed for skeletal reconstruction, with emphasis on mechanoresponsive scaffolds, bioactive composites, and integrated microsensors for real-time monitoring. We explore material formulations that enhance osseointegration, resist micromotion-induced loosening, and modulate inflammatory responses at the bone-implant interface. Additionally, we assess novel fabrication methods-such as additive manufacturing and gradient-based material deposition-for tailoring stiffness, porosity, and degradation profiles to match host biomechanics. Special attention is given to sensor-augmented platforms capable of detecting mechanical …

The Only Constant Is Change: The Role Of Genetic Diversification In Cancer And Beyond, Malgorzata Tyczynska Weh

USF Tampa Graduate Theses and Dissertations

Genetic diversification, the process by which genetic variation arises in a population, is fundamental to evolution by natural selection. Mutation, a central diversification process, fuels adaptation across species, including in cancer. Yet most new mutations are neutral or deleterious on cell fitness, raising the question of how mutation-driven adaptation persists. To explore this paradox, I developed a spatial agent-based model (ABM) in which population fitness emerges from individual cells acquiring mutations at varied rates and with diverse fitness effects. I evaluated model behavior across adaptive states, mutation rates, and distributions of fitness effects. The results show that high mutation rates …

Quality Improvement Project Enhance Self-Efficacy And Knowledge In Pediatric Emergency Care For Nurses In An Adult Acute Care Facility, Tiffany Daniel

Doctor of Nursing Practice Projects

This Doctor of Nursing Practice (DNP) project addresses the significant gap in emergency nursing preparedness for managing pediatric emergencies in adult-focused emergency departments. A quasi-experimental pre/ post intervention design was used to implement a pediatric-specific training intervention consisting of didactic education and simulation-based learning. A total of 87 night shift ED nurses participated. Knowledge and self-efficacy were measured using pre- and post-intervention surveys and assessments. The training equipped nurses with critical skills to manage pediatric emergencies more confidently and competently, addressing both clinical and emotional barriers. Knowledge scores significantly improved, t = -20.45, p < 0.001, with post-test means rising from 5.56 (SD = 1.58) to 9.03 (SD = 0.32). Post-intervention self-efficacy scores also increased significantly, t(86) = -21.57, p < .001, indicating greater confidence in pediatric emergency care. These findings validate the effectiveness of structured pediatric emergency training in enhancing nurse competency and self-efficacy. Lewin's change theory and Newman’s systems model guided this quality improvement project. The results support the continuation of the program in population-specific education and simulation as part of annual competency development. This project demonstrated that targeted pediatric training improves nurse preparedness and has the potential to enhance patient outcomes in a setting traditionally focused on adult care.

Quality Improvement Project Supporting Novice Nurse Faculty Through Mentorship, Lorna Deardeuff

Doctor of Nursing Practice Projects

Current literature suggests that a lack of support to assist novice faculty in their socialization to academia can lead to increased attrition among faculty members. However, novice nursing faculty, when transitioning from the role of clinical expert, require much support to successfully meet the demands of preparing nursing students. This quality improvement project aimed to develop and implement a structured novice nurse faculty mentorship program, with the use of a mentorship toolkit, to improve job satisfaction levels and the intent of the novice faculty members to remain in their current positions. This quasi-experimental project utilized a pre-and-post intervention survey designed …

Hypertensive Disorders Of Pregnancy And Perinatal Outcomes: Two Prospective Cohort Studies Of Nulliparous Women In India And Tanzania, Andrea B. Pembe, Pratibha Dwarkanath, Amani Kikula, John Michael Raj, Nandita Perumal Phd, Heavenlight A. Paulo, Rajalakshmi M, Christopher P. Duggan, Honorati M. Masanja, Nandini Chopra, Mary M. Sando, Tinku Thomas, Cara A. Yelverton, Alfa Muhihi, Anura V. Kurpad, Wafaie E. Fawzi, Blair J. Wylie, Christopher R. Sudfeld

Faculty Publications

Introduction Hypertensive disorders of pregnancy (HDP) have been linked with increased risk for maternal and offspring complications in high-income settings. However, in resource-limited settings, studies with robust measurement of HDP, including severity and timing, and perinatal outcomes are limited.

Methods We analysed data from two prospective cohorts of nulliparous women in India (n=10 570 pregnancies) and Tanzania (n=10 299 pregnancies) who were enrolled in calcium supplementation trials and had blood pressure and proteinuria assessments throughout pregnancy and at the time of labour and delivery. Generalised estimating equations were used to assess the relationship between HDP severity categories (gestational hypertension, preeclampsia …

Microscopic Nucleic Acid-To-Protein Ratio: A Label-Free Approach For Pancreatic Cancer Detection, Sky Gao, Keerthi Priya Jangili, Alfred Akinlalu, Emmanuel Ogberefor, Tommy Gao, Kalpana Devaraj, Dali Sun

Electrical and Computer Engineering: Faculty Scholarship

Accurate and timely diagnosis remains a major clinical challenge, hindered by the limitations of conventional histopathological methods, which often rely on labor-intensive staining protocols and subjective interpretation by specialized pathologists. These methods can fail to capture the full molecular and phenotypic heterogeneity of tumors, leading to increased diagnostic time, cost, and variability. To overcome these challenges, we developed a novel label-free ultraviolet (UV) microscopic imaging technique that exploits the intrinsic optical absorption properties of cellular nucleic acids and proteins. By modifying standard brightfield microscopes, our approach quantitatively measures the nucleic acid-to-protein ratio (NPr), enabling high-resolution visualization and discrimination between malignant …

Enhancing Learning Through Role-Play In A Low-Fidelity Disaster Simulation, Susan S. Braithwaite, Susan J. Barcinas, Colleen A. Hayes

Innovations in Health Sciences Education Journal

ABSTRACT

Background: This report shares a best practice approach to low-fidelity simulation as a pedagogical method in disaster triage training for undergraduate nursing students.

Methods: This study utilized multi-year quantitative data such as student age, gender, GPA, prior simulation experience, and self-reported confidence in the START Triage application. It also utilized a secondary qualitative analysis of the debriefing process.

Results: Students who participated in a simulation event playing the role of a disaster victim scored significantly higher on subsequent performance as TRIAGE practitioners than students without roleplay experience. Perhaps even more compelling, these learning outcomes were demonstrated 18 months after …

Human Alveolar Macrophage Response To Mycobacterium Tuberculosis: Immune Characteristics Underlying Large Inter-Individual Variability, Wolfgang Sadee, Ian H. Cheeseman, Audrey Papp, Maciej Pietrzak, Michal Seweryn, Xiaofei Zhou, Shili Lin, Hao Zhang, Blanca I. Restrepo, Yufeng Wang

School of Medicine Publications

Mycobacterium tuberculosis (M.tb) infection infects human alveolar macrophages (HAMs). In freshly isolated HAMs from 28 healthy adults, we observe large inter-individual differences in bacterial uptake and growth, with tenfold variation in M.tb load by 72 h. While M.tb infection triggers expression changes of numerous host mRNAs, we examined which genes are most variably expressed (VE genes) between donors, as potential biomarkers of individual tuberculosis (TB) risk. The HAM RNA transcriptome following infection revealed thousands of differentially expressed (DE) genes and differential secretion of 25/27 proteins. Yet only 324 DE genes represent VE genes detected exclusively among DE genes in …

Effect Of The Cervical Lesion Severity On Procedural And Clinical Outcomes After Endovascular Treatment Of Acute Tandem Lesions: A Multicenter Study, Milagros Galecio-Castillo, Mudassir Farooqui, Ameer E. Hassan, Mouhammad A. Jumaa, Afshin A. Divani, Marc Ribo

School of Medicine Publications

Background

Tandem lesions pose unique challenges in the endovascular treatment of acute ischemic stroke. We aimed to compare the clinical and procedural outcomes of patients with tandem lesions and extracranial internal carotid artery (ICA) complete occlusion versus those with moderate to severe stenosis.

Methods

This is a subanalysis of a multicenter cohort of patients with acute anterior circulation tandem lesions treated with intracranial mechanical thrombectomy and carotid artery stenting, between January 2015 and December 2020. The patients were categorized into 2 groups: extracranial ICA stenosis >70% to 99% and complete occlusion. Outcomes included successful and excellent recanalization, functional independence, symptomatic …

Exploring Predictors Of Treatment Response To Glp-1 Receptor Agonists For Smoking Cessation, Luba Yammine, Constanza De Dios, Robert Suchting, Charles E Green, David A Nielsen, Consuelo Walss-Bass, Joy M Schmitz

Faculty, Staff and Student Publications

Introduction: Understanding predictors of smoking cessation medication efficacy facilitates the ability to enhance treatment effectiveness. In our pilot trial, exenatide, a glucagon-like peptide-1 receptor agonist, adjunct to nicotine patch improved smoking abstinence compared to nicotine patch alone. This secondary analysis explores potential baseline characteristics associated with differential treatment response to exenatide.

Aims and methods: The parent trial randomized (1:1) 84 smokers with prediabetes and/or overweight to once-weekly placebo or exenatide, 2 mg, subcutaneously. All participants received nicotine patch (21 mg) and brief smoking cessation counseling, with biologically confirmed 7-day point prevalence abstinence at week 6 (end-of-treatment) deemed the primary outcome. …

Multiscale Modeling Of Drug-Induced Liver Injury From Organ To Lobule, Alon Malka-Markovitz, Stelian Camara Dit Pinto, Mohammed Cherkaoui, Steven M Levine, Sharmila Anandasabapathy, Gagan K Sood, Sadhna Dhingra, Gao Yujia, John M Vierling, Nicolas R Gallo

Center for Medical Ethics and Health Policy Staff Publications

Drug-induced liver injury poses significant challenges in drug development and in clinical care. This study builds on prior work developing a Human Liver Virtual Twin by creating a Multiscale Computational Fluid Dynamics framework that integrates patient-specific anatomical data to predict acetaminophen-induced liver injury as a demonstration of its capability. The model bridges vascular, lobular, and cellular scales to simulate dynamic blood flow, drug transport, and injury mechanisms that accurately reflect clinically observed spatial heterogeneity. Results demonstrate accurate blood flow dynamics, predictions of hepatocellular damage, and a scalable framework for studying spatial heterogeneity applicable to other hepatic pathologies. This work establishes …

Patterns Of Sialyl-Lewis X Expression Predict Gastric Histopathology, Nancy Vargas, Andrés Quiroga, Juan Pablo Chaves, Harold Bolaños, Ilke Nalbantoglu, Claudia Patricia Acosta Astaiza, Yuefeng Wu, José B Sáenz

2020-Current year OA Pubs

INTRODUCTION: Gastric cancer develops through a series of pre-cancerous changes over decades of chronic inflammation. Chronic atrophic gastritis (CAG) represents a critical transition in the progression to gastric cancer, though validated histologic markers are needed to more accurately detect and assess the extent of CAG. We previously identified sialyl-Lewis X (sLe

METHODS: We obtained gastric corpus and/or antrum biopsies from 149 adult patients with dyspepsia. Biopsies were stained with hematoxylin/eosin and a commercially available antibody to sLe

RESULTS: The majority of patients (70%) had gastric pathology (CNG or CAG ± IM). The presence of sLe

CONCLUSION: Patterns of sLe

Supplemental Data: Analyzing Point Of Care Tools Through Faculty, Resident, And Stakeholder Buy-In: Promises And Pitfalls, J. Michael Lindsay

Faculty Publications

Costs for UpToDate, the library’s primary point of care clinical tool, had increased to half of the acquisitions budget but without user affiliation data to facilitate cost sharing. A working group led by librarians was formed to review alternatives. Surveys indicated users preferred UpToDate and renewal was recommended by the working group, with costs being shared between the academic unit and the hospital. These results showed that the library can effectively lead analysis projects with this level of visibility, but persuading users to consider alternatives to a trusted tool can be challenging.

Appendix 1 is a general survey meant to …

Enhancing Education In Nursing Skills: The Impact Of Simulation Use On Faculty Self -Efficacy, Annie Kyle

Doctor of Nursing Practice Projects

This quality improvement (QI) project aimed to improve nursing faculty self-efficacy in teaching nursing skills using medium- and high-fidelity simulation. The problem addressed was the increasing number of students requiring multiple attempts to pass skills checkoffs, with some ultimately being withdrawn from the program. Faculty at the project site reported a lack of training and confidence in utilizing simulation technology effectively. A quasi-experimental design was used with a single group of full-time faculty (n=6), who received simulation training and completed the Self-Efficacy Towards Teaching Inventory for Nurse Educators (SETTI-NE) before and after the intervention. The data analysis was conducted using …

Improving Patient Outcomes Post-Discharge: Implementing Evidence-Based Discharge Planning For High-Risk Mental Health And Substance Use Disorder Populations, Margaret Phillips

Doctor of Nursing Practice Projects

A significant gap in standardized discharge procedures was identified at a nonprofit, community-based clinic serving male residential patients with substance use disorder (SUD) and co-occurring mental health conditions. The lack of a standardized discharge process led to poor follow-up appointment adherence, poor medication adherence and increased risk of relapse. This quality improvement (QI) project aimed to address these issues through the implementation of a cross-departmental discharge process that produced tailored Individualized Discharge Plans (IDP) or each patient, using the Donabedian and Kotter’s 8-Step Change models as guiding frameworks. Data were collected using custom-built tracking tools over two four-week periods, pre- …

Quality Improvement Project The Introduction Of Gratitude Journaling To Decrease Test Anxiety In Prelicensure Bachelor Of Science In Nursing Students, Jourdan Scoggins

Doctor of Nursing Practice Projects

Test anxiety is a substantial barrier to success among prelicensure nursing students, given the heavy course load and high academic pressure of the educational environment. The purpose of this quality improvement project was to measure the impact of gratitude journaling on levels of test anxiety in first-semester Bachelor of Science in Nursing (BSN) enrolled in a nursing math course at a regional university in Arkansas. Following a quasi-experimental design, students participating in the project completed the Westside Test Anxiety Scale (WTAS) before and after five weeks of gratitude journaling. Thirty-two students participated in the intervention and 24 of those completed …

Detecting Early Changes In Cartilage Collagen And Proteoglycans Distribution Gradients In Mice Harboring The R992c Collagen Ii Mutant Using 2d Correlation Infrared Spectroscopy, Jolanta Fertala, Andrzej Steplewski, Andrzej Fertala

Department of Orthopaedic Surgery Faculty Papers

Collagen II is a vital structural component in developing bones and mature cartilage. Muta- tions in this protein cause spondyloepiphyseal dysplasia, a disease characterized primarily by altered skeletal growth and manifesting with a range of phenotypes, from lethal to mild. This study examined transgenic mice harboring the R992C (p.R1124C) substitution in colla- gen II. Previous research demonstrated significant growth abnormalities and disorganized growth plate structure in these mice, and histological signs of osteoarthritic changes in the knee joints of 9-month-old mice with the R992C mutation. Our study focuses on detecting early structural changes in the articular cartilage that occur before …

Head To Head Comparison Of Two Pet/Ct Imaging Agents, [18f]D3fsp ([18f]P16-129) And [18f]Av45, In Patients With Alzheimer’S Disease, David Alexoff, Dean F Wong, Hiroto Kuwabara, Robert F Dannals, Karl Ploessl, Hank F Kung

2020-Current year OA Pubs

BACKGROUND: A new β-amyloid (Aβ) targeting radiotracer, [

RESULTS: Eight patients, clinically diagnosed with Alzheimer's disease, had an average age of 61.1 ± 10.0 years, and an average MMSE score of 21 ± 4. Each patient underwent paired 90-minute dynamic PET/CT scans separately within a few weeks (323 ± 31 MBq of [

CONCLUSIONS: Results showed no difference between [

TRIAL REGISTRATION: Clinicaltrials.org, NCT03902548. Registered 01/07/2018.

Cancer Immunotherapy Clinical Trials To Support Urgently Needed Access In Low- And Middle-Income Countries: A Report From The Sitc Global Access And Impact Committee, Jennifer Dent, Thomas A Odeny, Et Al.

2020-Current year OA Pubs

Cancer is rapidly on the rise as a cause of morbidity and mortality in low- and middle-income countries (LMICs). However, despite the increasing importance of immune checkpoint inhibitors (ICIs) as a pillar of cancer therapy, access in these settings lags well behind that in high-income countries (HICs). Increasing the evaluation of ICIs through local clinical trials and demonstration projects, and inclusion in multinational clinical trials is the first step to improving access. In particular, the epidemiology and clinical presentation of cancer in LMICs is often distinct from that in HICs, and the impact of immune checkpoint blockade in these settings …

Dysferlinopathy As Cause Of Long-Term Hyperckemia With Preserved Strength, Ikreet Cheema, Jacob Goodwin, Teerin Liewluck, Robert Charles Bucelli, Alan Pestronk, Margherita Milone

2020-Current year OA Pubs

BACKGROUND: Dysferlin (DYSF) has a crucial role in sarcolemmal repair. While DYSF mutations commonly manifest as limb-girdle muscular dystrophy (LGMDR2) or distal Miyoshi myopathy, atypical manifestations, such as asymptomatic hyperCKemia and pseudometabolic myopathy, are rarely reported. We describe clinical, serologic, radiologic, genetic, and muscle pathology findings of three patients with rare dysferlinopathy phenotypes and long-term follow up in one of them. We also review the literature pertinent to uncommon forms of dysferlinopathy presenting with hyperCKemia and pseudometabolic phenotype.

RESULTS: Patient 1 is a 51-year-old female with exercise-induced myalgia predominantly affecting calf muscles for 7 years. She had a 22-year history …