Medicine and Health Sciences Commons^™

Building Access To Care For Women And Girls+ With Bleeding Disorders: The Wgbd Clinic Of Excellence Model, Ming Y. Lim, Katherine C. Anguiano, Shannon L. Carpenter, Kerry B. Funkhouser

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Associations Among Human Milk Polyunsaturated Fatty Acids And Infant Sleep Patterns: A Cross-Sectional Study, Ana M Palacios, Dominick J Lemas, Bridget E Young, Erik Parker, Stephanie Dickinson, Nandi Marshall, Kelly L Sullivan, Haley Wilt, Michelle I Cardel, David B Allison

Children’s Nutrition Research Center Staff Publications

Background: Infant sleep is critical for cognitive, emotional, and long-term health outcomes. Although diet-sleep relationships are established, limited research has explored how polyunsaturated fatty acids (PUFAs) in human milk (HM) relate to infant sleep.

Objectives: This study aims to examine associations between PUFAs in HM and sleep patterns in 2-mo-old infants exclusively fed with HM.

Methods: This cross-sectional secondary analysis used data from a lactation cookie trial involving 131 parents of healthy, term infants. Participants provided a fasting HM sample and completed sociodemographic and Brief Infant Sleep Questionnaire surveys. Multivariate linear models were adjusted for infant sex assigned at birth, …

All-Cause And Cause-Specific Mortality Among Patients With Narcolepsy., Chih-Wei Hsu, Yen-Shan Yang, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai

Children’s Nutrition Research Center Staff Publications

Importance: Narcolepsy is a sleep disorder potentially affecting mortality, yet evidence on this association remains sparse.

Objective: To examine whether narcolepsy is associated with an increased risk of all-cause and cause-specific mortality.

Design, setting, and participants: This retrospective cohort study used data from the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2021, with patients followed up until death or December 31, 2022. Patients were aged 6 years or older with 2 or more narcolepsy diagnoses from psychiatrists or neurologists. Controls were selected from the NHIRD as a population-based sample. Controls without narcolepsy were matched in a 1:4 …

Menopause Factors And Alterations In Gut Microbiota And Insulin Homeostasis: A Cross-Sectional Analysis Of The Microbiome And Insulin Longitudinal Evaluation Study (Miles), Vincent J Maffei, Alain G Bertoni, Alexis C Wood, Jerome I Rotter, Osa Crago, Yii-Der I Chen, Joseph F Petrosino, Kristi L Hoffman, Mark O Goodarzi, Elizabeth T Jensen

Children’s Nutrition Research Center Staff Publications

Aim: To assess the risk for impaired insulin homeostasis as a function of menopause-related factors and gut microbiota dysbiosis in non-diabetic, post-menopausal women.

Materials and methods: Baseline data (n = 175 women) from the Microbiome and Insulin Longitudinal Evaluation Study (MILES) were used, including insulin and dysglycaemia indices calculated from a 2-h oral glucose tolerance test, untargeted peripheral metabolomics, targeted peripheral short chain fatty-acid levels and faecal bacterial microbiota surveyed by whole-metagenomic sequencing.

Results: After adjustment for covariates, menopause age < 50 years and use of hormone replacement therapy (HRT) were associated with lower Matsuda et al. insulin sensitivity index levels (β = -0.232, confidence interval (CI) = [-0.450, -0.014] and β = -0.275, CI = [-0.444, -0.107], respectively) but not pre-menopausal gynaecologic surgery. Pre-menopausal gynaecologic surgery was significantly associated with faecal microbiota beta diversity driven by a relative increase in diabetogenic Ruminococcus gnavus and Clostridium species and a decrease in protective Alistipes species and Akkermansia muciniphila relative abundances. A reduction in two glycerophospholipids in the plasmalogen class significantly statistically mediated an inverse association between gynaecologic surgery before menopause and insulin sensitivity.

Conclusions: Menopause age and history of HRT are more strongly associated with insulin resistance than gynaecologic surgery before menopause. However, …

Nrf2 Immunobiology In Cancer: Implications For Immunotherapy And Therapeutic Targeting, Harit Panda, Natalie G Rowland, Caroline M Krall, Brittany M Bowman, Michael B Major, Paul Zolkind

2020-Current year OA Pubs

Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that acts as a key regulator in cellular defense mechanisms against oxidative stress and xenobiotics. NRF2 modulates the expression of over 200 genes involved in antioxidant response, drug metabolism, and cellular resilience. Constitutive activation of NRF2 is a common event in cancer and recent advances provide remarkable insights into the role of NRF2 in oncogenesis, immune evasion, and treatment resistance. This review aims to provide a comprehensive overview of the role of NRF2 in shaping the tumor immune microenvironment and the impact this has on clinical outcomes and treatment …

Targeting Rna With Small Molecules Using State-Of-The-Art Methods Provides Highly Predictive Affinities Of Riboswitch Inhibitors, Narjes Ansari, Chengwen Liu, Florent Hédin, Jérôme Hénin, Jay W Ponder, Pengyu Ren, Jean-Philip Piquemal, Louis Lagardère, Krystel El Hage

2020-Current year OA Pubs

Targeting RNA with small molecules represents a promising yet relatively unexplored avenue for the design of new drugs. Nevertheless, challenges arise from the lack of computational models and techniques able to accurately model RNA systems, and predict their binding affinities to small molecules. Here, we tackle these difficulties by developing a tailored state-of-the-art approach for absolute binding free energy calculations of RNA-binding small molecules. For this, we combine the advanced AMOEBA polarizable force field to the newly developed lambda-Adaptive Biasing Force scheme associated to refined restraints allowing for efficient sampling. To capture the free energy barrier associated to challenging RNA …

Distinct Roles For B Cell-Derived Ltα3 And Ltα1Β2 In Tnf-Mediated Ileitis, Emma C Erlich, Quazim A Alayo, Ayoung Kim, Jichang Han, Rachel L Mintz, Christopher G Huckstep, Heather S Ruiz, Rachael L Field, Taylor J Dunning, Leila S Saleh, Mark H Hoofnagle, Farshid Guilak, Jonathan R Brestoff, Rafael S Czepielewski, Gwendalyn J Randolph, Et Al.

2020-Current year OA Pubs

Crohn's disease pathology is modeled in TNF

Brugia Malayi And Other Filarial Parasite Species In Animals In Areas Endemic For Lymphatic Filariasis In Belitung District, Indonesia, Irina Diekmann, Taniawati Supali, Kerstin Fischer, Elisa Iskandar, Noviani Sugianto, Yossi Destani, Rahmat Alfian, Gary J. Weil, Peter U. Fischer

2020-Current year OA Pubs

BACKGROUND: Brugia malayi is the most common cause of lymphatic filariasis (LF) in Indonesia. A zoophilic ecotype that infects both humans and animals occur in Belitung District in Indonesia. The district received five annual rounds of mass drug administration (MDA) between 2006 and 2010 and passed three transmission assessment surveys (TAS) in subsequent years. However, a survey in five villages in 2021 showed a microfilaria (Mf) prevalence of 2.1% in humans. The reappearance of B. malayi infection in humans may be due to reintroduction from animal reservoirs. The goal of this study was to determine B. malayi prevalence in potential …

Gut Complement System: A New Frontier In Microbiota-Host Communication And Intestinal Homeostasis, Xianbin Tian, Lan Zhang, Xinyang Qian, Yangqing Peng, Fengyixin Chen, Sarah Bengtson, Zhiqing Wang, Meng Wu

2020-Current year OA Pubs

The gut microbiota plays a crucial role in maintaining intestinal homeostasis and influencing various aspects of host physiology, including immune function. Recent advances have highlighted the emerging importance of the complement system, particularly the C3 protein, as a key player in microbiota-host interactions. Traditionally known for its role in innate immunity, the complement system is now recognized for its interactions with microbial communities within the gut, where it promotes immune tolerance and protects against enteric infections. This Review explores the gut complement system as a possibly novel frontier in microbiota-host communication and examines its role in shaping microbial diversity, modulating …

Aging And The Spectral Properties Of Brain Hemodynamics, Ki Yun Park, Abraham Z Snyder, Manu S Goyal, Timothy O Laumann, John J Lee, Babatunde Adeyemo, Nicholas Metcalf, Andrei G Vlassenko, Joshua S Shimony, Eric C Leuthardt

2020-Current year OA Pubs

Cerebral glucose metabolism (CMRGlc) systematically decreases with advancing age. We sought to identify correlates of decreased CMRGlc in the spectral properties of fMRI signals imaged in the task-free state. Lifespan resting-state fMRI data acquired in 455 healthy adults (ages 18-87 years) and cerebral metabolic data acquired in a separate cohort of 94 healthy adults (ages 25-45 years, 65-85 years) were analyzed. The spectral properties of the fMRI data were characterized in terms of the relative predominance of slow versus fast activity using the spectral slope (SS) measure. We found that the relative proportion of fast activity increases with advancing age …

Multi-Period Risk-Aware Procurement Optimization Under Covid-19 Disruption, Jonathan Chase, Hoong Chuin Lau, Jinfeng Yang, Lu Liu

Research Collection School Of Computing and Information Systems

Supply chain resilience has been a topic of active research in the operations research and AI communities for several years, but the COVID-19 pandemic threw the frailties of global supply chains into sharp relief. Disruptions and delays caused by fresh outbreaks leading to lockdowns, put severe strain on supply chains in many industries. In this work we develop lockdown-resilient procurement capabilities for a global technology company. First, through analysis of lockdown data from China we develop a logarithmic regression-based lockdown prediction method to complement a supplier risk metric for conventional risks. Second, we develop a multi-period stochastic optimization model that …

Real-Time Task Scheduling Strategy For 3d Printing Cloud Platforms In Health Scenes, Jianjia He, Jian Wu, Jingran Ni, Yuning Zhang, Keng Siau

Research Collection School Of Computing and Information Systems

In health scenes, 3D Printing Cloud Platform (3DPCP) needs to cope with unpredictable fluctuations in tasks and resources, but traditional scheduling methods have problems such as incomplete consideration of factors, poor optimization, and weak dynamic adaptability, which make it difficult to meet real-time scheduling requirements. To this end, the real-time task scheduling problem of 3DPCP for health scenes is defined, a real-time task scheduling model is established, the design time of user personalized services is considered, a rescheduling scheme is designed in combination with task variations and device variations, and a scheduling strategy that incorporates dynamic mechanisms and improved multi-objective …

Artificial Intelligence And Academic Integrity In Nursing Education: A Mixed Methods Study On Usage, Perceptions, And Institutional Implications, Maggie Zgambo, Martina Costello, Melanie Buhlmann, Justine Maldon, Edah Anyango, Esther Adama

Research outputs 2022 to 2026

Background: The rise of artificial intelligence (AI) use in higher education has generated substantial debate among academics and students, given the potential for students to engage in academic misconduct through the misuse of AI. Academics argue that AI poses a serious threat to the foundational development of nurses through the questionable integrity of AI-generated academic work and by undermining the development of critical thinking skills essential for professional practice. However, there is limited research on nursing students' integration of AI technologies in their studies.

Method: This study utilised a convergent parallel mixed methods approach to develop a multiphase approach with …

Implementation Fidelity Of A Smartphone Application For Population-Based General Movement Assessment: The Early Moves Study, Caroline F. Alexander, Sarah E. Hall, Alison Salt, Alicia J. Spittle, Catherine Morgan, Tiffany Grisbrook, Alishum Ali, Natasha Amery, Sue Anne Davidson, Ashleigh Thornton, Mary Sharp, Emily Young, Robert S. Ware, Desiree Silva, Roslyn Ward, Nadia Badawi, Samudragupta Bora, Roslyn N. Boyd, Susan Woolfenden, Catherine Elliott, Jane Valentine

Research outputs 2022 to 2026

Objective: To describe the infant and maternal characteristics of the Early Moves cohort and to assess representativeness to the general population, and to evaluate the implementation fidelity of an application-based collection of General Movement Assessment (GMA) videos at writhing and fidgety age. Study design: Prospective observational study. Mothers who had recently delivered or were enrolled to deliver at maternity hospitals in Perth, Western Australia, were recruited from November 2019 to December 2023. Sociodemographic and infant clinical characteristics were extracted from hospital records. Parents were invited to record GMA videos using the Baby Moves smartphone application, which were assessed for scorability …

Evaluating The Impact Of The ‘Blow, Breathe, Cough’ Health Promotion Intervention In Resolving Otitis Media With Effusion In Children: An Adaptive Randomized-Controlled Trial Protocol, Jaimee R. Rich, Michael Dymock, Elke J. Seppanen, Elena Montgomery, Tanisha Cayley, Tamara Veselinović, Greta Bernabei, Anri Lester, Amy Hannigan, Nicole Irvine, Kerryn Gidgup, Edna Ninyette, Steph Bray, Tu Trang Tran, Valerie M. Swift, Melinda Edmunds, Natalie Strobel, Daniel Mcaullay, Julie Marsh, Evelyn Tay, Lea Ann S. Kirkham, Ruth B. Thornton, Robyn S.M. Choi

Research outputs 2022 to 2026

Introduction: Otitis media with effusion (OME) affects hearing, speech development, and quality of life (QoL) in children. The ‘Blow, Breathe, Cough’ (BBC) intervention promotes nasal, respiratory, and middle ear clearance through nose blowing, deep breathing, coughing, and hand hygiene. It shows promise in resolving OME but lacks randomized-controlled trial (RCT) evaluation. This paper presents a RCT protocol evaluating BBC's effect on OME resolution, hearing, speech, and QoL in children aged two to seven years. Methods: This parallel-group, 1:1, outcome assessor-blinded, individual adaptive RCT investigates whether completing the BBC intervention plus hand hygiene twice-daily at home increases OME resolution after 4-to-6 …

Global Perspectives Of Midwifery Ethics: Crucial Features For Practice Via An International Delphi Study, Kate Buchanan, Sara Bayes, Elizabeth Newnham, Mavis Kirkham, Marianne Nieuwenhuijze

Research outputs 2022 to 2026

Background: Practising ethically as a midwife is essential for providing high quality care during pregnancy, childbirth, and the postpartum period. Whilst midwives may have theoretical knowledge of ethics, applying ethical care in practice may be challenging. There is a gap in the literature that describes how midwives themselves conceptualise, interpret, and apply ethics in their practice. Aim: To describe midwives’ perceptions, and experiences of ethics in midwifery practice, and to determine the crucial features of midwifery ethics. Methods: Fifty participants from 21 countries participated in the study. A two-round Delphi approach was employed. Round Two required participants to enter the …

Co-Design Of A Weekly Meal Box For Neurological Conditions: Findings From Consumer And Healthcare Provider Collaborative Workshops, Joanna Rees, Kelly Moes, Amanda Devine, Melanie Clark, Ros Sambell, Simon Laws, Travis Cruickshank

Research outputs 2022 to 2026

Introduction: This study explores the collaborative co-design process for developing a weekly meal box tailored for individuals with neurological conditions. Recognising the critical role of nutrition for this community, the research addresses the challenges posed by cognitive and physical impairments in meal preparation. Methods: Through two co-design workshops involving consumers, healthcare providers and industry experts, insights were gathered on dietary preferences, nutritional needs and practical challenges. Results: The workshops emphasised the importance of convenient, easy-to-prepare meals with simple instructions, flexibility and customisability. Consumers expressed preferences for convenient, easy-to-prepare meals with simple, easy-to-follow recipe instructions that align with optimal dietary patterns …

Sleep Environment Is Associated With Sleep Control In Fly-In, Fly-Out Mining Shift Workers, Philipp Beranek, Mitchell Turner, Johnny Lo, Michael Grandner, Ian C. Dunican, Travis Cruickshank

Research outputs 2022 to 2026

Control over sleep timing, duration, and quality is essential for obtaining healthy sleep. Fly-in, Fly-out (FIFO) mining shift workers face unique challenges in maintaining control over their sleep due to their roster. However, the impact of their sleep environment on perceived sleep control in this population remains underexplored. This study evaluates the sleep environment of FIFO mining shift workers and its association with sleep control. A cross-sectional study was conducted (2023–2024) on Australian FIFO mining shift workers residing in remote camp accommodations. Data were collected via an online survey using the Assessment of Sleep Environment (ASE) and the Brief Index …

Effects Of Exercise On Inflammation In Female Survivors Of Nonmetastatic Breast Cancer: A Systematic Review And Meta-Analysis, Francesco Bettariga, Dennis R. Taaffe, Anita Borsati, Alice Avancini, Sara Pilotto, Stefano G. Lazzarini, Pedro Lopez, Luca Maestroni, Umberto Crainich, John P. Campbell, Timothy D. Clay, Daniel A. Galvão, Robert U. Newton

Research outputs 2022 to 2026

Background: Despite advances in breast cancer treatment, recurrence remains common and contributes to higher mortality risk. Among the potential mechanisms, inflammation plays a key role in recurrence by promoting tumor progression. Exercise provides a wide array of health benefits and may reduce inflammation, potentially reducing mortality risk. However, the effects of exercise, including mode (ie, resistance training [RT], aerobic training [AT], and combined RT and AT) and program duration, on inflammatory biomarkers in breast cancer survivors remain to be elucidated. Methods: A systematic search was undertaken in PubMed, CINAHL, Embase, SPORTDiscus, and CENTRAL in August 2024. Randomized controlled trials examining …

Healing Right Way: A Stepped Wedge Cluster Randomised Controlled Trial Aiming To Enhance Quality Of Life For Aboriginal Australian Survivors Of Stroke And Traumatic Brain Injury, Elizabeth Armstrong, Tapan Rai, Judith M. Katzenellenbogen, Sandra J. Thompson, Meaghan Mcallister, Natalie Ciccone, Deborah Hersh, Leon Flicker, Dominique A. Cadilhac, Erin Godecke, Graeme J. Hankey, Neil Drew, Colleen Hayward, Deborah Woods, Mel Robinson, Ivan Lin, Sanita Kratina, Jane White, Juli Coffin

Research outputs 2022 to 2026

Objective: To determine the effect of cultural security training (CST) for health professionals and access to an Aboriginal Brain Injury Coordinator (ABIC) for Aboriginal Australians with stroke or traumatic brain injury (TBI). Design: A stepped wedge cluster randomised controlled trial; the intervention package consisted of CST for hospital professionals and 6-month access to ABICs providing education, support, liaison and advocacy; the commencement order of the intervention phase was randomised. Setting: Four urban and four rural hospitals in Western Australia, 2018–2022. Participants: Aboriginal adults ≥ 18 years hospitalised with stroke or TBI. Main Outcome Measures: Primary outcome was quality of life …

I Know What To Say Now: Students' Evaluation And Utilisation Of Accidental Counsellor Training, Joanna E. Harnett, Claire E. Ashton-James, James Kite, Tonia Crawford, Sanetta H.J. Du Toit, Leigh A. Wilson, Rosa Howard

Research outputs 2022 to 2026

Introduction In 2020 and 2021, 280 health profession students who were engaged in student leadership roles and peer mentoring were invited to undertake extracurricular training in accidental counselling to build skills in recognising and responding to a person in distress. The aim of this study was to evaluate the acceptability of the online training course, and to explore students’ confidence to use Accidental Counsellor tools to support peers in distress after completion of the training course. Methods A retrospective cohort study including a post- intervention only design was used. A survey was administered approximately 12 months after 225 students completed …

Systematic Review And Meta-Analysis Of Microrna-7-5p Expression And Biological Significance In Head And Neck Squamous Cell Carcinoma, Rikki A.M. Brown, Michael Phillips, Andrew J. Woo, Omar Kujan, Stephanie Flukes, Louise N. Winteringham, Larissa C. Dymond, Fiona Wheeler, Brianna Pollock, Dianne J. Beveridge, Elena Denisenko, Peter J. Leedman

Research outputs 2022 to 2026

Background: Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignancy with poor clinical outcomes. microRNA-7-5p (miR-7-5p) has been described as both a tumour suppressor and an oncomiR depending on the tissue context, but its role in HNSCC remains unclear. This study aimed to clarify the clinical significance and biological function of miR-7-5p in HNSCC by integrating data from multiple sources. Methods: A systematic review of the literature was conducted to identify studies analysing miRNA expression in human head and neck tissues. A meta-analysis of individual patient data from Gene Expression Omnibus (GEO), ArrayExpress, and The Cancer Genome Atlas …

Minimizing Travel Burden Of Gynecologic Cancer Surveillance Through A Unique Multidisciplinary Telehealth Program, Avni Shridhar, Suzanne Viator, Tara Castellano, Holly Provost, Navya Nair, Elizabeth Neupert, Amma Agyemang, Amelia Jernigan

School of Medicine Faculty Publications

OBJECTIVE: STEEL MAGNOLIAS (shared telehealth for multidisciplinary gynecologic cancer survivorship) is a novel gynecologic cancer surveillance care-delivery program in which rural patients see a close-by gynecologist in person with simultaneous virtual gynecologic oncology consultation. This study assesses feasibility of STEEL MAGNOLIAS by examining travel burden reduction, cancer outcomes, visit activities, guideline adherence, and patient satisfaction. METHODS: We retrospectively reviewed charts of patients with gynecologic cancer in remission under the STEEL MAGNOLIAS program in rural south Louisiana (March 2020-September 2023). Travel metrics, patient satisfaction, cancer outcomes, survival status, reasons for visit, and adherence to follow-up as per National Comprehensive Cancer Network …

An Online Treatment Decision Aid For Men With Low-Risk Prostate Cancer Eligible For Active Surveillance And Their Partners Increases The Uptake Of Active Surveillance: The Navigate Randomised Controlled Trial, Penelope Schofield, Stephen Quinn, Natalie Richards, Alan White, Fiona White, Mark Frydenberg, Suzanne Chambers, Louisa G. Gordon, Robert Alexander Frank Gardiner, Declan G. Murphy, Matthew J. Roberts, John Yaxley, Nathan Lawrentschuk, Kevin Chu, Jeremy Millar, Jeremy Grummet, Ilona Juraskova

Research outputs 2022 to 2026

Background and objective: Evidence suggests that curative treatment for low-risk prostate cancer (LRPC) has no survival benefits over active surveillance (AS); thus, treatment choice becomes a value-sensitive decision. Decision aids (DAs) have the potential to facilitate this process, yet no DA has been tailored to the Australian health care system or population. This study aims to evaluate the impact of an online DA (Navigate) on the uptake of AS, quality of life, and decision-making in Australia. Methods: This parallel-group, prospective, randomised controlled trial recruited men (from May 2017 to May 2021) from participating cancer centres, via self-referral, or via clinician …

Advancing University Student Health And Wellbeing Through Peer-Led Health Promotion: A Quality Improvement Project​ ​, Rojeda Merani, Elizabeth Page, Elizabeth Roth

DNP Projects

Background: Peer-led health promotion is widely recognized as an effective strategy for increasing engagement, trust, and health literacy among university students. However, few frameworks guide development and implementation of these programs.

Objective: To evaluate the feasibility, implementation process, and perceived effectiveness of a peer-led health promotion model supported by Doctor of Nursing Practice (DNP) mentorship at a mid-sized private university.

Participants: Thirteen undergraduate students from a diverse set of academic programs were recruited as Peer Health Ambassadors (PHAs) and paired with DNP student mentors.

Methods: Guided by the Implementation Research Logic Model, the project used a four-phase QI process: targeted …

The Efficacy Of Emdr Therapy Compared To Tf-Cbt In Adopted Children To Manage Post-Traumatic Stress: An Integrative Review, Grace Ann Steiner

Senior Honors Theses

This integrative review examines the efficacy of eye movement desensitization and reprocessing (EMDR) therapy compared to trauma-focused cognitive behavioral therapy (TF-CBT) in managing post-traumatic stress disorder (PTSD) in adopted children. Children adopted from foster care tend to experience more adverse childhood experiences (ACEs) and maladjustment issues when compared to the general population, which necessitates effective therapeutic interventions to reduce PTSD symptoms and emotional dysregulation. Through analysis and comparison of the data, it was determined that both EMDR and TF-CBT effectively alleviated trauma-related symptoms, although one technique is not necessarily always more effective or efficient than the other. Along with reviewing …

The Science Of Sound: Studying The Cognitive, Emotional, And Physiological Effects Of Frequency, Genre, And Music, Jett Yarborough

Senior Honors Theses

Music influences emotion, physiology, and cognition, yet little is known about how the frequency it is tuned to affects these influences. Prior research has shown that music tuned to 432 Hz can reduce stress, lower blood pressure, and improve sleep. My colleagues and I conducted two studies to investigate this. Our research found that music tuned to 432 Hz promotes a significant increase in memory retention and induces a state of focus and relaxation. These results suggest that shifting from the standard tuning frequency of 440 Hz to 432 Hz could have a profoundly positive impact on our daily lives. …

Artificial Intelligence And Medical Education (2013-2024): A Scopus-Based Bibliometric Analysis, Festus Mulakoli, Edward Misava

School of Nursing & Midwifery, East Africa

Background: Artificial Intelligence (AI) is transforming medical education by enabling personalised learning, adaptive feedback, simulation-based training, and automated assessments. While AI offers significant benefits, including curriculum optimisation and virtual tutoring, concerns around data privacy, access, and ethical implementation persist. Although bibliometric studies have explored AI in healthcare, comprehensive analyses of global collaboration and publication trends in AI-focused medical education remain limited. Aim: This study aims to analyse global research trends, key contributors, and thematic developments in the application of AI within medical education. Methods: A bibliometric analysis was conducted using the Scopus database. The search strategy included terms …

Program Evaluation Of Tms Treatment For Patients With Comorbid Major Depressive Disorder And Ptsd, Alec Wilson

Doctor of Nursing Practice

Nearly six million in the U.S. experience symptoms associated with the diagnoses of comorbid Major Depressive Disorder (MDD) and Post Traumatic Stress Disorder (PTSD). Many with these diagnoses fail to respond to first line treatments that include medication and psychotherapy. Transcranial magnetic stimulation (TMS) therapy is a non-invasive treatment option for individuals who fail to respond to first line treatments.

Methods: This program evaluation completed a retrospective chart review of adult patients with comorbid MDD and PTSD, who received TMS treatments at a private practice clinic between the time frame of September 2024 and October of 2025.

Results: All …

An Evidence-Based Practice Review: Outpatient Opioid, Narcan, And Non-Opioid Treatments For Pain Management, Kayla Culp

Doctor of Nursing Practice

Background: There were nearly 645,000 deaths from 1991-2021 related to opioid overdose. Despite the U.S. representing only four percent of the global population, Americans consume 80% of the world’s opioids. Ten million Americans misuse opioid prescriptions, and this contributes to the thousands of annual deaths. Preventable mortality related to the opioid epidemic persists despite advancements in primary, secondary, and tertiary prevention efforts.

Purpose: The purpose of this evidence-based practice (EBP) project was to compare components of CDC’s (Center for Disease Control and Prevention) Clinical Practice Guideline for Prescribing Opioids for Pain to current prescribing practices amid an ongoing …