Medicine and Health Sciences Commons^™

Evaluation Of The Impact Of Coriander Sativum Extract On The Modulation Of Inflammatory And Oxidative Enzymes In Ptz Induced Epilepsy In A Rat Model, Rusul Ali Kadhim, Zahraa Saleem Manji

Maaen Journal for Medical Sciences

Background

Recurrent and spontaneous seizures are a symptom of the epilepsy. It affects up to 65 million individuals globally, with lower-income nations accounting for 80% of cases. Since medicinal plants have special therapeutic qualities, they are frequently used to manage and cure epilepsy and convulsions. Because they have fewer side effects and stronger therapeutic results, medicinal plants are becoming more and more popular worldwide as a result of increased research and clinical use. The pharmaceutical industry is now concentrating heavily on the creation of novel plant-based antiepileptic/anticonvulsant drugs

Aims of the study:

Study the role of coriander sativum extraction in …

Latine Doctoral Student Experiences In U.S. Counselor Education And Supervision Programs, Nayara Aparecida Da Costa Silva Beall, Lizbeth Duran Oden, Isabel C. Farrell, Mariaimeé Gonzalez, Stephanie Thorson-Olesen

Journal of Counselor Preparation and Supervision

This study explored the experiences of Latine doctoral students in Counselor Education and Supervision programs in the United States. The consensual qualitative research yielded five domains: cultural values, representation, racialized experiences, support, and social justice. The findings are discussed with direct applications for programs and recommendations for future research.

Counselor Education: Digital Delivery With Confidence, Nicole Marie Arcuri-Sanders, Alisha Davis

Journal of Counselor Preparation and Supervision

Counselor education programs are required to demonstrate a clear framework, effective implementation, and overall program effectiveness. The pandemic’s surge in online instruction influenced CACREP’s (2024) digital delivery (DD) standards, addressing ethical and legal implications alongside student outcomes. Guidance from digital health initiatives, telemental health ethics and legal practices can be invaluable in clarifying DD protocols for counselor education programs. Understanding the parallels between DD and digital health regulations (e.g., HIPAA, ACA [2014], and NBCC [2023] ethical codes) provides a solid foundation for protecting both students and programs. Integrating technology and modeling digital health practices can enhance counselor education, benefiting both …

In Vivo Pharmacokinetic Evaluation Of A Gastro-Retentive Triple Drug Delivery System Utilizing Natural Polymers For Enhanced Helicobacter Pylori Eradication, Edukulla Satheesh Kumar, Hindustan Abdul Ahad, Thirumalesh Naik Sugali Banoth

Bulletin of Faculty of Pharmacy Cairo University

This study evaluates the in vivo pharmacokinetics of triple-drug gastro-retentive formulation (metronidazole- Plantago ovata seed mucilage/ clarithromycin- Abelmoschus esculentus fruit mucilage/enteric-coated pantoprazole) for Helicobacter pylori eradication, with a focus on pharmacokinetic parameters (e.g., relative bioavailability vs. conventional doses) as the true contribution. In a cross over study using six rabbits, plasma concentrations of metronidazole, clarithromycin, and pantoprazole sodium were measured via High Performance Liquid Chromatography technique, and pharmacokinetic parameters were determined. A single dose of the optimized formulation (C-8) produced optimal drug levels, with a mean Cmax of 24.36 ± 0.84 μg/mL and tmax at 6 hours. The other pharmacokinetic …

Governors Slightly More Bound? A Critique Of The Uniform Law Commission's Model Public-Health Emergency Authority Act, Paul A. Diller

Kentucky Law Journal

No abstract provided.

Evaluation The Awareness Of Using Brushing And Interdental Cleaning Aids Among Dental Students In Najaf City, Iraq, Ali Faisal Madhloom, Firas Bashir Al-Taweel, Mustafa Faris Shubbar, Ali Falah Rfysh

Maaen Journal for Medical Sciences

Background: The consensus is that overall health is significantly impacted by oral health. It is anticipated that dental students will have a strong understanding of oral health. The aim of this preliminary pilot study was to evaluate of the awareness of using tooth brushing and interdental cleaning aids between dental students from 1^st grade to 5^th grade in Najaf city, Iraq.

Methods: A cross-sectional study and questionnaire with 12 questions was based on the use of brushing tongue and interdental cleaning aids were conducted among 1^st grade to 5^th grade dental students in Alkafeel …

Aging And The Screen: Toxic Commodification Of The Female Body In The Substance (2024), Damlasu Uyug Sengun, Tuncer Mert Aydın, Zeynep Ozdamar Ertekin

Markets, Globalization & Development Review

Representations of the aging female body have increased in media, but their presence is still shaped by social norms and market-driven ideals. On the contrary, The Substance (2024), an absurd, postmodern body horror, provides us a provocative critique of contemporary society’s obsession with youth and beauty and the way our culture defines and commodifies aging, especially in relation to women’s bodies and identities. Our review of The Substance incorporates consumer culture theory with Julia Kristeva’s concept of the abject (1982), Laura Mulvey’s theory of the male gaze (1975), and Barbara Creed’s notion of the monstrous-feminine, (1993) to explore the toxic …

Comparative Analysis Of Tuberculosis Treatment Costs: Drug-Resistant Vs. Drug-Sensitive Cases In Vietnam, Thi-Kim-Thang Dao, Dao Dinh, Mai-Hien Chuc, Hai-Anh Ha

Bulletin of Faculty of Pharmacy Cairo University

This study analyses the economic and clinical implications of treating pulmonary tuberculosis (TB), focusing on direct treatment costs and patient outcomes at Da Nang Hospital for Lung Diseases in Vietnam. Data were collected from 448 inpatient TB cases throughout 2022, encompassing both drug-sensitive and drug-resistant forms of TB. Analysis revealed that drug-resistant TB patients incur significantly higher treatment costs compared to those with drug-sensitive TB, with costs escalating further among older adults and patients with multiple comorbid conditions. Specifically, treatment for drug-resistant TB averaged $463.84 per patient, significantly surpassing the $217.09 average for drug-sensitive cases, indicating the economic burden posed …

Two Cases Of Intramyocardial Dissecting Hematoma Diagnosed By Echocardiography, Jianbo Wu, Fei Bian, Xijun Zhu, Xin Du, Tao Hao, Qian Liu

Journal of Community Hospital Internal Medicine Perspectives

Intramyocardial dissecting hematoma (IDH), a rare complication of myocardial infarction, was investigated through two unique clinical cases in this study. We demonstrate echocardiography's pivotal role in emergency diagnostics by detailing its critical contribution to rapid identification. Furthermore, we propose a hypothesis regarding the anatomical subtypes of IDH, potentially offering new perspectives and insights into this rare cardiac condition.

Mmp-7 Expression And Rs11225307 Polymorphism In Breast Cancer And Fibroadenoma: A Molecular Study In Basrah, Iraq, Heba Jassam, Wijdan Nazar Ibraheim, Mazin Hawwaz Abdulridha, Rafid Adil Abood, Karam B. Nanjem

AUIQ Complementary Biological System

Breast cancer (BC) progression relies heavily on extracellular matrix degradation, mediated in part by matrix metalloproteinase-7 (MMP-7). While overexpression of MMP-7 has been implicated in multiple cancers, data from Middle Eastern populations remain limited.

This study examined MMP-7 gene expression and polymorphism patterns, with emphasis on rs11225307, in breast cancer versus benign fibroadenoma (FA) tissues among women in Basrah, Iraq. Thirty-seven BC and twenty-three FA patients were enrolled. MMP-7 mRNA expression was quantified using qRT-PCR and normalized to β-actin, while polymorphisms were analyzed through Sanger sequencing of eight SNPs and allele-specific PCR for rs11225307. Statistical significance was set at …

Cv: Donna Martin (Nursing), Donna Martin

Nursing Department Faculty Curricula Vitae

No abstract provided.

Collaborative Cost Reduction: Leveraging Interdepartmental Partnerships, Jennifer Demarco, Kiersten Walzer

Nursing Research and EBP Day 2025

No abstract provided.

Implementing Evidence-Based Strategies For Falls Prevention, Gregory Njong

Walden Dissertations and Doctoral Studies

Older adults are particularly susceptible to post-fall injuries and loss of independence. This project was implemented to decrease the number of resident falls within a long-term care setting by enhancing the knowledge and daily routine of direct-care personnel. Falls remain one of the most frequent and severe safety concerns. Although policies on fall prevention are in place, workers often inconsistently incorporate risk evaluation and fail to identify all the causes of a fall. The purpose of this project was to determine whether a structured educational program could raise the level of knowledge about fall-prevention and provide safer care practices. The …

Staff Education To Acute Care Nursing Staff On Physical Medicine And Rehabilitation, Melissa Marie Emeott

Walden Dissertations and Doctoral Studies

For this Doctor of Nursing Practice project in physical medicine and rehabilitation (PM&R), the focus was on enhancing education for acute care nurses about the benefits of inpatient rehabilitation for appropriate patients. The practice problem was the underutilization of inpatient rehabilitation despite its proven benefits in improving patient outcomes and reducing readmissions. With this project, I aimed to educate nurses on identifying suitable candidates for inpatient rehabilitation, thereby improving patient care transitions and outcomes. The practice-focused question revolved around assessing the effectiveness of educational interventions in increasing nurse knowledge and referral rates to inpatient rehab. Analytical strategies included pre- and …

A Boost Of Confidence: Improving Perinatal Bereavement Care, Kimberly Winn

Student Scholarly Projects

Practice Problem: Perinatal loss can have a profoundly distressing impact on families. Nurses play a crucial role in supporting care during this challenging period and must be confident in perinatal bereavement care.

PICOT: The PICOT question that guided this Doctor of Nursing Practice (DNP) Scholarly Project was, in inpatient hospital Maternal Child Health (MCH) nursing staff (P), does implementing a standardized perinatal bereavement care checklist (I), compared to current practice (C), improve nurse confidence in perinatal bereavement care as evidenced by the Perinatal Bereavement Care Confidence Scale (PBCCS) (O) in eight weeks (T)?

Evidence: Ten evidence-based articles were included in …

Executive Summary: Multi-Departmental Resilience And Stress Reduction Program, Joy Adeyemi

Walden Dissertations and Doctoral Studies

Background: Primary care nursing faces an escalating burnout crisis threatening patient safety and organizational sustainability. Internal data reveals 68% of primary care nurses report high emotional exhaustion scores on the Maslach Burnout Inventory (MBI), significantly exceeding the national average of 45%. Annual voluntary turnover of 28% results in direct replacement costs exceeding $750,000, with associated increases in absenteeism (15% higher) and overtime costs (22% higher) compared to regional benchmarks. Purpose: This quality improvement project implemented a comprehensive multi-departmental resilience and stress reduction program to reduce nurse burnout, improve retention, and enhance patient safety outcomes in a primary care setting serving …

Development Of A Clinical Practice Guideline For Diabetic Ketoacidosis (Dka) Management In The Intensive Care Unit, Kushom Gurung Leftwich

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project addressed a critical gap in care at a 24-bed, combined, intensive care unit (ICU): The absence of a standardized, evidence-based clinical practice guideline (CPG) for managing diabetic ketoacidosis (DKA). DKA is a life-threatening emergency requiring timely, coordinated, and evidence-driven management. Despite its prevalence, the project site ICU lacked formal guidelines, resulting in fragmented care delivery and inconsistent treatment practices. Project site leadership expressed concerns that the absence of a unified protocol contributed to increased workload for nurses and physicians with frequent interruptions for order verification and delays that compromised patient safety and care …

Editorial: Migration And Health: A Human Rights Perspective - Conference Insights And Beyond, Noemi Rodriguez, Mira Goral, Justine Mcgovern, Allison Squires, María Isabel Roldos

Publications and Research

No abstract provided.

Repetitive Head Impacts: Definitional Challenges, Clinical Implications, And Research Directions, Amanda Rabinowitz, Allie Tracey, Yevgeniya Sergeyenko

Department of Rehabilitation Medicine Faculty Papers

Purpose of Review: Repetitive head impacts (RHI)—repeated head trauma that may or may not result in clinically identified injury—are a growing public health concern due to links with neurodegenerative disease and long-term dysfunction. This review aimed to synthesize current knowledge of RHI and evaluate methodological challenges that limit conclusions about its clinical consequences. Recent Findings: Emerging studies highlight associations between RHI and cognitive, emotional, and functional outcomes across vulnerable populations including athletes, military personnel, and survivors of intimate partner violence. However, definitional ambiguity, difficulties in measuring exposure, and population-specific confounds continue to hinder progress. Clinical approaches emphasize individualized assessment and …

Cv: Laura Olson (Radiography), Laura Olson

Rehabilitation and Health Sciences Department Faculty Curricula Vitae

No abstract provided.

Investigating The Impact Of Health Information Exchange On Hospital Performance: Evidence From The United States, C. Christopher Lee, Ruoqing Zhang

International Journal of Applied Management and Technology

This study examines the impact of health information exchange (HIE) participation on hospital performance in the United States, focusing on profitability, efficiency, and quality. Analyzing data from 3,294 hospitals over 3 years (2014–2016) and using multiple regression models, the results showed a positive association between HIE participation and improved performance. HIE membership is linked to increased profitability, enhanced efficiency, and certain quality enhancements, particularly in larger, metropolitan, for-profit hospitals. However, the relationship with quality outcomes is less conclusive. The comprehensive analysis considers various control variables, and the findings of this study offer valuable insights for hospital managers and policymakers and …

Cv: Laura Olson (Radiography), Laura Olson

Health Sciences Department Curricula Vitae

No abstract provided.

Investigating The Effectiveness Of Technology On The Enhancement Of Independent Living Skills For Individuals With Intellectual Developmental Disabilities (Idd) In The Moka Smart Home., Kelsey Alexander, Jadyn Boogaard, Grace Mccartney, Madison Maziasz, Nicolette Werner

Masters Projects

This study explored the effectiveness of technology on the enhancement of independent living skills for individuals with intellectual developmental disabilities (IDD) in two MOKA smart homes. Using a quantitative research approach, the study examined how assistive technology can aid individuals with IDD to increase independence in their living skills. This research was conducted in two pilot residential homes, a men's home and a women's home. Three women and two men participated in the study. Data was collected through observation and client report utilizing the Routine Task Inventory Expanded version (RTI-E). RTI-E sections assessed for this study were the Physical (ADL), …

Mta-Cooperative Prmt5 Inhibitors Are Efficacious In Mtap-Deleted Malignant Peripheral Nerve Sheath Tumor Models, Xiaochun Zhang, Dana C Borcherding, Yang Lyu, Guangfeng Wang, Kevin He, Gorkem Oztosun, Ishita Sachdeva, Liuzhan Yang, Kuangying Yang, Angela C Hirbe, Et Al.

2020-Current year OA Pubs

PURPOSE: Malignant peripheral nerve sheath tumors (MPNST) are highly aggressive sarcomas with poor prognosis. The enzyme methylthioadenosine phosphorylase (MTAP) is lost in ∼25% to 50% of MPNSTs, which is associated with loss of the tumor suppressor gene CDKN2A. Inhibition of PRMT5 was found to be synthetically lethal in cells with MTAP loss due to accumulation of the substrate methylthioadenosine (MTA), an endogenous PRMT5 inhibitor. TNG908 and TNG462 are clinical-stage MTA-cooperative PRMT5 inhibitors that demonstrate selectivity for MTAP-deleted (null) cells over MTAP-proficient [wild-type (WT)] cells. Both compounds drive durable tumor regressions in various cancer xenograft models with MTAP loss.

EXPERIMENTAL DESIGN: …

Sulindac Sulfide Suppresses Oncogenic Transformation Through Let-7b-Mediated Repression Of K-Ras Signaling, Zhipin Liang, Ruixia Ma, Bin Yi, Adam I. Riker, Yaguang Xi

School of Graduate Studies Faculty Publications

No abstract provided.

Validation Of A Two-Item Short Form Of The Perceived Health Competence Scale, Devika Nair, Jacquelyn S Pennings, Hayden B Bosworth, Kenneth E Freedland, Sunil Kripalani, Elisa J Gordon, Gurjeet S Birdee, Justin M Bachmann

2020-Current year OA Pubs

BACKGROUND: Perceived health competence is a construct encompassing individuals’ confidence in managing their health and health-related behaviors. The 8-item Perceived Health Competence Scale (PHCS-8), developed to measure this construct, has established psychometric properties including test-retest reliability and predictive validity for health behaviors and clinical outcomes. We aimed to validate the 2-item Perceived Health Competence Scale (PHCS-2), an abbreviated version of the PHCS-8, for use in clinical and research settings where respondent burden is a primary concern. METHODOLOGY: We conducted a psychometric validation study using pooled data from 482 participants across two cohort studies conducted in an integrative medicine clinic. Participants …

Ethical And Legal Concepts For Pt, Clarence Chan

Open Educational Resources

This course introduces the topics of medical ethics and legal issues as applied to physical therapy practice. Students will have the opportunity to apply legal and ethical theories and concepts to analyze and discuss issues faced by healthcare practitioners. Ethical and legal standards set forth by the legal system in the United States, the Standard of Practice of New York State, and the American Physical Therapy Association core ethics documents will be explored. Students will also become familiarized with the various aspects of administrative, financial, quality improvement, and personnel management information as related to health care practice in the United …

Management Of Stenotrophomonas Mediastinitis After Heart Transplantation For Persistent Driveline Infection: A Case Report, James Lee West, Charles W. Hoopes, Jeremey Walker, Anoma Nellore, Erik J. Orozco-Hernandez

Department of Surgery Faculty Papers

We report a 62-year-old male who had a Heartware left ventricular assist device (LVAD) implantation and subsequently developed a persistent driveline infection, culminating in an abscess along the driveline site despite 18 months of antibiotic treatment. His situation was further complicated post-transplant by the onset of mediastinitis, linked to a previously undervalued Stenotrophomonas maltophilia infection. This report highlights the potential risks of heart transplantation in patients with unresolved LVAD driveline infections, particularly mediastinitis. The presence of existing driveline infections, combined with the immunosuppressed status of patients, necessitates aggressive surgical measures. Our treatment approach, involving multiple mediastinal washouts, omental flap use, …

Mapping Respiratory Health Digital Interventions In South And Southeast Asia: A Scoping Review, Laura Evans, Jay Evans, Paul Barach, Adina Abdullah, Zakiuddin Ahmed, Respire Collaboration

College of Population Health Faculty Papers

BACKGROUND: The growing burden of respiratory disease, particularly in Asia, where mortality is higher and awareness and policy engagement lag, could be mitigated through rapidly advancing digital health tools that offer opportunities for improved management, prevention, and personal health empowerment. We aimed to map the existing evidence, technologies, opportunities, and gaps related to respiratory digital health interventions in South and Southeast Asia and propose relevant recommendations.

METHODS: We used a scoping review methodology, where we searched MEDLINE, Embase, CINAHL, PsycINFO, Cochrane Library, Web of Science, PakMediNet, and MyMedR along with grey literature databases (ProQuest Thesis and Dissertations, Digital Health Atlas, …

The Efficacy Of Topical Paromomycin-Gentamicin Versus Topical Paromomycin Alone In The Treatment Of Cutaneous Leishmaniasis: A Meta-Analysis Of Randomized Controlled Trials, Tareq Alshaikh, Mohammed Jihad, Awwad Jomaa

Sultan Qaboos University Medical Journal

Cutaneous leishmaniasis (CL) is the most common protozoal skin infection worldwide. Multiple treatments for CL have been developed to address issues related to resistance, availability, and safety. Topical treatments have shown promise by reducing unnecessary systemic exposure and providing a viable local therapeutic option. A systematic review and meta-analysis were conducted of all literature published before 28 February 2025 through PubMed/MEDLINE, the Cochrane Library, and EBSCO, comparing topical paromomycin–gentamicin (PG) with topical paromomycin alone (PR). Two studies involving a total of 774 patients were included. Relative risks (RRs) from both studies were pooled using a fixed-effect meta-analysis. The meta-analysis showed …