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2025

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Full-Text Articles in Medicine and Health Sciences

Evaluation And Reduction Of Pediatric Precaution Alert Volume Across A Large Community Health System, Sarah Ferrell Pharmd Jan 2025

Evaluation And Reduction Of Pediatric Precaution Alert Volume Across A Large Community Health System, Sarah Ferrell Pharmd

Parkview Pharmacy Department

Presented at the Midyear Clinical Meeting.

This evaluation found the potential to remove 15,174 alerts per year. Based off a physician spending a median of 8 seconds processing an alert, a reduction of 15,174 alerts per year saves about 34 hours of physician work-time per year.


Stool Rules: Evaluation Of Fidaxomicin Use Before And After Formulary Addition And Implementation Of Use Criteria, Anna Koeva Pharmd Jan 2025

Stool Rules: Evaluation Of Fidaxomicin Use Before And After Formulary Addition And Implementation Of Use Criteria, Anna Koeva Pharmd

Pharmacy Residency

Presented at the Midyear Clinical Meeting.

This evaluation found that appropriate use of fidaxomicin improved after addition to formulary with use restrictions, along with a decrease in 30-day CDI recurrence.


Naloxone Addition To The Nursing Admission Order Set: A Retrospective Review, Sydney Pelnick Pharmd Jan 2025

Naloxone Addition To The Nursing Admission Order Set: A Retrospective Review, Sydney Pelnick Pharmd

Pharmacy Residency

Presented at the Midyear Clinical Meeting

Nurse access to naloxone improved after implementation of standing order. Post-implementation outcomes demonstrated more appropriate use of naloxone. An increase in opioid utilization within 12 hours of naloxone supports a greater use for intended purpose.


Catch Flights, Not Rsv: Real-World Evaluation Of Respiratory Syncytial Virus (Rsv) Vaccine Use In Maternal And Older Adult Populations, Afamefuna Nzekwe Jan 2025

Catch Flights, Not Rsv: Real-World Evaluation Of Respiratory Syncytial Virus (Rsv) Vaccine Use In Maternal And Older Adult Populations, Afamefuna Nzekwe

Pharmacy Residency

Present at the Midyear Clinical Meeting.

This evaluation found that most vaccinated patients met criteria. About 1/3 of newborns received RSV protection, but post-birth nirsevimab use could not be confirmed for non-Parkview patients.


Evaluating A Clinical Pharmacist's Role In An Internal Medicine Graduate Medical Education Primary Care Residency Clinic, Le Thien Truc Pham Pharmd Jan 2025

Evaluating A Clinical Pharmacist's Role In An Internal Medicine Graduate Medical Education Primary Care Residency Clinic, Le Thien Truc Pham Pharmd

Pharmacy Residency

Presented at the Midyear Clinical Meeting

Approximately 98% of all survey participants were satisfied with the clinical pharmacy services. Diabetes management was found to be the most valuable pharmacy service.


Parent Social Media Use And Gaming On Mobile Phones, Technoference In Family Time, And Parenting Stress., Brandon Mcdaniel, Alison K. Ventura, Michelle Drouin Jan 2025

Parent Social Media Use And Gaming On Mobile Phones, Technoference In Family Time, And Parenting Stress., Brandon Mcdaniel, Alison K. Ventura, Michelle Drouin

Health Services and Informatics Research

Possible effects of parent phone use on parent–child interactions and child behavior are of concern, warranting research to understand parent phone use. In this survey study of 183 families with a young child (M = 2.89 years), we examined parents’ phone use for texting/calling, social media (SM) use, mobile gaming (MG), and perceptions of cutting into family time; we also examined differences between mothers and fathers and associations with parenting stress. Mothers engaged in greater SM use but less MG compared to fathers; 61% of mothers and 38% of fathers used SM 31+ min per day, while 23% of …


The Anatomy Of A Reconstruction: From Fourier Space To Image Recovery In Computed Tomography, Charlotte P. Maurer Jan 2025

The Anatomy Of A Reconstruction: From Fourier Space To Image Recovery In Computed Tomography, Charlotte P. Maurer

Honors Theses

This thesis develops the mathematical foundations of computed tomography (CT) reconstruction through the lens of harmonic analysis. Beginning with the Schwartz class, we introduce the Fourier transform and its role in expressing the Radon transform and its inversion via a fractional Laplacian. After constructing the Radon transform in general dimension R^d, we specialize to the cases d = 2 and d = 3, demonstrating explicit inversion formulas and the associated instability in lower dimensions. For its computational advantages, we study filtered back-projection using classical low-pass filters (Ram-Lak, Shepp–Logan, Cosine, Gaussian) and formulate a discrete reconstruction algorithm grounded in …


How Does Cocaine Exposure Affect Early Gene Expression Changes In The Prefrontal Cortex (Pfc) And Striatum?, Saathvika Diviti Jan 2025

How Does Cocaine Exposure Affect Early Gene Expression Changes In The Prefrontal Cortex (Pfc) And Striatum?, Saathvika Diviti

Honors Theses

Cocaine use disorder (CUD) remains a significant public health concern, yet the molecular mechanisms underlying individual susceptibility are poorly understood. This study investigates early transcriptional responses to acute cocaine exposure in two key brain regions implicated in addiction, the prefrontal cortex (PFC) and striatum, using genetically diverse Diversity Outbred (DO) mice. Paired tissue samples were collected following a standardized sensitization protocol and analyzed via bulk RNA sequencing. Differential expression analysis revealed 37 significantly differentially expressed genes in the striatum. These genes overlapped with gene sets associated with substance use, neurodevelopmental disorders, and immune signaling, implicating shared pathways in central nervous …


Ai-Infused Discussion Boards: Enhancing Engagement, Reflection, And Academic Integrity In Anatomy And Physiology Education, Wade Dauberman Jan 2025

Ai-Infused Discussion Boards: Enhancing Engagement, Reflection, And Academic Integrity In Anatomy And Physiology Education, Wade Dauberman

Teaching Repository of AI-Infused Learning

This paper presents the design, implementation, and evaluation of an AI-infused discussion board assignment that promotes ethical AI engagement, enhances student learning in anatomy and physiology, and addresses academic integrity concerns in higher education.


Mind The Gap, Klaire Perry Jan 2025

Mind The Gap, Klaire Perry

OTD 721: Cultural Responsiveness & Occupation

I went in to OT to make the world more accessible. I love how OT views people as their hopes, dreams, values, strengths, and facilitators...NOT as an injury or disease. At this point, every room I enter becomes a personal case study of accessibility. I can't help but wonder how many spaces have hung huge signs that say "YOU ARE NOT WELCOME" that are only visible to some. I'm thankful for my love ones who agreed to help me with this project. While I can never fully understand their experience, I can listen.

Klaire Perry, Class of 2027


Summer School: The Experience Of An Occupational Therapy Student Exploring Culture In Spokane!, Lulu Brady Jan 2025

Summer School: The Experience Of An Occupational Therapy Student Exploring Culture In Spokane!, Lulu Brady

OTD 721: Cultural Responsiveness & Occupation

This zine illustrates my experience in this OTD 721 Cultural Responsiveness class, led by Dr. Kirkpatrick. The class took place in the summer of 2025. It was absolutely inspiring, and I wanted to be able to share my takeaways and learnings from my experiences in this class. Culture is so relevant to the field of occupational therapy (OT) because occupations are often shaped by culture, OT cannot be truly client-centered without respective culture. Not only did this class help me grow as a future occupational therapist practitioner, but it also helped me grow as a person. It showed me the …


Welcomed In: A Love Letter To Okinawa, Taylor Fernandez Jan 2025

Welcomed In: A Love Letter To Okinawa, Taylor Fernandez

OTD 721: Cultural Responsiveness & Occupation

This zine is a personal, reflective project exploring Okinawan culture through my lens as a long-term guest -- first as a military child, then as an adult returning "home" to visit the island where my parents still live. While I am not Okinawan, the culture has deeply influenced my values, worldview, and understanding of community, aging, and wellness.

Through this project, I have sought to honor the richness of Okinawan traditions -- not as an authority, but a someone shaped by the grace of being welcomed in. The pages blend scholarly knowledge, lived experience, and cultural observation to explore how …


Occupational Apartheid, Kimberly Dewey Jan 2025

Occupational Apartheid, Kimberly Dewey

OTD 721: Cultural Responsiveness & Occupation

Occupational apartheid is a term that is often misunderstood. I wanted to bring more awareness and understanding to a very real concept that happens every day. I hope to have provided education and examples that make it easy to follow along and see how apartheid shows up on a daily basis. Let's work together as future OT professionals to expand our knowledge and practice to decrease experiences of occupational apartheid.

Kimberly Dewey, Class of 2027


Autism And The Delay Of Diagnosis In African American Communities, Kiara Loud Jan 2025

Autism And The Delay Of Diagnosis In African American Communities, Kiara Loud

Theses and Dissertations

Autism Spectrum Disorder (ASD) is a developmental disability accompanied by a wide range of neurodevelopmental disorders. ASD can affect anyone regardless of race, socioeconomic status, or ethnicity (CDC, 2025). Individuals with ASD tend to have issues with various challenges and strengths regarding how they learn, think, and solve problems. Some children with ASD have repetitive patterns of behavior, restricted interest in activities, and difficulty in communication and social interaction.

According to the World Health Organization, the global prevalence of ASD 1 in 100 children diagnosed with Autism. Additional data supplied by the CDC states that the number of children with …


Mental Health Trends Among African American High School Students, Alexis Heard Jan 2025

Mental Health Trends Among African American High School Students, Alexis Heard

Theses and Dissertations

Adolescent mental health is a major public health issue in the U.S., with African American high school students facing a rapidly worsening crisis. While all youth show increasing rates of depression, anxiety, and suicidality, African American adolescents are at greater risk due to systemic racism, socioeconomic inequality, community violence, and limited access to culturally responsive care. Few national studies have examined mental health trends among this group. This study (1) examines 2011–2021 trends in persistent sadness/hopelessness, suicidal ideation, suicide planning, and suicide attempts among African American high school students; (2) explores gender differences; and (3) compares these patterns to national …


Perinatal Policy Disparities And Their Impact On Maternal, Paternal, And Child Health, D'Ashanae Y. Pippens Jan 2025

Perinatal Policy Disparities And Their Impact On Maternal, Paternal, And Child Health, D'Ashanae Y. Pippens

Theses and Dissertations

This systematic review synthesized evidence on perinatal policy framework to evaluate their public health significance and impact on family outcomes. Following Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) methodology, peer-reviewed literature, policy documents, and corporate data from 2015-2025 were reviewed across national, state, and global levels. The analysis revealed seven thematic domains, (1) policy design and duration, (2) wage replacement, (3) insurance continuity, (4) workplace breastfeeding accommodations, (5) parental leave, (6) equity in access, and (7) policy enforcement. Evidence shows that integrated and inclusive policies particularly those in Sweden, Germany, and progressive U.S. states (NY and CA), yield substantial …


Closing The Gap: Standardizing Sepsis Management To Address Racial Disparities Across Oregon Providence Hospitals, Jennifer Wong, Do, Shelley Schoepflin Sanders Jan 2025

Closing The Gap: Standardizing Sepsis Management To Address Racial Disparities Across Oregon Providence Hospitals, Jennifer Wong, Do, Shelley Schoepflin Sanders

Abstracts, Posters, Presentations

No abstract provided.


Addressing The Prescribing Patterns And Environmental Impact Of Dry Powder Inhalers (Dpi) Versus Metered Dose Inhalers (Mdi), Abby Lindseth, Md, Claudia Leonard, Shelley Schoepflin Sanders Jan 2025

Addressing The Prescribing Patterns And Environmental Impact Of Dry Powder Inhalers (Dpi) Versus Metered Dose Inhalers (Mdi), Abby Lindseth, Md, Claudia Leonard, Shelley Schoepflin Sanders

Abstracts, Posters, Presentations

No abstract provided.


Puzzling Papules: Uncovering The Etiology Of A Rash In A Returning Traveler, Lisa Stampke, Md, Shahana Baig-Lewis Md, Mph Jan 2025

Puzzling Papules: Uncovering The Etiology Of A Rash In A Returning Traveler, Lisa Stampke, Md, Shahana Baig-Lewis Md, Mph

Abstracts, Posters, Presentations

No abstract provided.


Characterization Of Sarcoidosis At A Combined Rheumatology-Pulmonary Clinic, Megan Schermerhorn, Md, Julianna Desmarais, Md Jan 2025

Characterization Of Sarcoidosis At A Combined Rheumatology-Pulmonary Clinic, Megan Schermerhorn, Md, Julianna Desmarais, Md

Books, Presentations, Posters, Etc.

Introduction: Sarcoidosis is a disease of unknown etiology characterized by formation of small clusters of inflammatory cells that form granulomas. Heterogenous and typically involves multiple organ systems with varying degrees of morbidity and mortality. Poorly defined treatment landscape. The purpose of this study was to characterize a cohort of sarcoidosis patients in a combined rheumatology-pulmonary clinic according to organ involvement and treatment over 5 years. Discussion: •Single center academic study of a that is the first of its kind. •Data highlights complexity and heterogeneity of patients with sarcoidosis and utility of combined rheumatology – pulmonary clinic. •65.3% of patients exhibited …


Unveiling The Mystery: Paraneoplastic Syndrome Masquerading As Skin Thickening, Megan Schermerhorn, Md, Quian Leng, Atish Dey Jan 2025

Unveiling The Mystery: Paraneoplastic Syndrome Masquerading As Skin Thickening, Megan Schermerhorn, Md, Quian Leng, Atish Dey

Books, Presentations, Posters, Etc.

Introduction: Systemic sclerosis is a rare autoimmune disorder defined by skin thickening in the distal digits and is frequently accompanied by inflammatory arthritis. There are known mimics of systemic sclerosis, which present with similar sclerosis of the skin. Palmar fasciitis and polyarthritis syndrome (PFPAS) is a rare paraneoplastic syndrome that presents with progressive flexion contractures of the hands, inflammatory fasciitis, fibrosis, and generalized inflammatory arthritis. PFPAS is most associated with ovarian adenocarcinoma, and rarely associated with pancreatic adenocarcinoma. Early recognition of this rare syndrome was critical in identifying an asymptomatic pancreatic adenocarcinoma. Case Description: 58-year-old woman with osteoarthritis of multiple …


Implementing Holograms To Perform Cognitive Health History Screenings, Franchesca I. Gonzalez Jan 2025

Implementing Holograms To Perform Cognitive Health History Screenings, Franchesca I. Gonzalez

Honors Undergraduate Theses

Marginalized populations, defined as a group of individuals who experience systematic disadvantages due to various social identity factors (Oxford Review, n.d.), experience uneven barriers to cognitive and mental health assessments, including socioeconomic, linguistic, and educational inequities, that contribute to misdiagnosis (Petersen et al., 2018, Saeed & Masters, 2021). This study investigates the feasibility of hologram-based patient simulations as an educational intervention for undergraduate nursing and graduate Nurse Practitioner students. Culturally representative, three-dimensional holographic patients were created to replicate complex geriatric encounters and facilitate cognitive health screenings. Established assessment tools, including the Mini-Mental Status Examination, Patient Health Questionnaire 2 and Patient …


A Systematic Literature Review On The Benefits Of Biofeedback Therapy As A Treatment For Diabetes Mellitus Induced Chronic Peripheral Neuropathy, Amy Krueger Jan 2025

A Systematic Literature Review On The Benefits Of Biofeedback Therapy As A Treatment For Diabetes Mellitus Induced Chronic Peripheral Neuropathy, Amy Krueger

Honors Undergraduate Theses

The objective of this systematic literature review is to examine the research on biofeedback therapy and evaluate its effectiveness in treating chronic diabetic peripheral neuropathy. This comprehensive review was conducted using the PRISMA 2020 method of analysis. All studies included at least 10 patients with T1D or T2D and current or past foot ulcers and/or DPN. Each study was also available in their entirety. Studies with fewer than 10 participants, those which examined neuropathy unrelated to diabetes, or those with healthy test populations were excluded. Studies that were only partially available were also not used. The databases used were PubMed, …


Ultra-Plex Immunofluorescence Stainings To Classify Precancerous Lesions For The Stratification Of Their Risk For Progression Toward Esophageal Squamous Cell Carcinoma, Arthi Jaishankar Jan 2025

Ultra-Plex Immunofluorescence Stainings To Classify Precancerous Lesions For The Stratification Of Their Risk For Progression Toward Esophageal Squamous Cell Carcinoma, Arthi Jaishankar

Honors Undergraduate Theses

Esophageal squamous cell carcinoma (ESCC) is the most common and fatal type of esophageal cancer since it is usually only diagnosed at a later stage. Similar to other cancers, ESCC arises through precursor lesions which are known as dysplasias and occurs when cells have uncontrolled growth and changes to both the tissue structure and gene expression. Clinical intervention at the precancerous stage would greatly improve survival rates, however predicting which lesions will actually become malignant continues to be a challenge. The current traditional method for ESCC diagnosis is hematoxylin and eosin (H&E) histopathology, but it is not sufficient for predicting …


Effect Of Sapropterin Dihydrochloride On Neuropsychiatric Functions For Individuals With Phenylketonuria: A Systematic Review, Ricky Lin Jan 2025

Effect Of Sapropterin Dihydrochloride On Neuropsychiatric Functions For Individuals With Phenylketonuria: A Systematic Review, Ricky Lin

Honors Undergraduate Theses

Phenylketonuria (PKU) is a rare metabolic disorder that occurs in approximately 1 in 10,000 births worldwide. Individuals with PKU cannot properly metabolize phenylalanine (Phe) due to a deficiency in phenylalanine hydroxylase (PAH), leading to elevated Phe levels and associated cognitive and neuropsychiatric impairments. Although early dietary management has reduced the risk of severe intellectual disability, many individuals with PKU continue to experience deficits in attention, executive functions, and mood regulation. Sapropterin dihydrochloride, a synthetic form of the PAH cofactor tetrahydrobiopterin (BH4), offers a pharmacological alternative that enhances residual enzyme activity in responsive individuals. While its efficacy in lowering blood Phe …


Lifetime History Of Concussions In Relation To Blind Perceptual Distance Estimation Ability, Mackenzie K. Miller Jan 2025

Lifetime History Of Concussions In Relation To Blind Perceptual Distance Estimation Ability, Mackenzie K. Miller

Honors Undergraduate Theses

This study examined the relationship between visuospatial estimation and a lifetime history of concussions. Current literature on concussions investigates visuospatial working memory and estimation ability separately, but not conjointly. In order to examine this relationship, a novel neuropsychological task was designed to measure visuospatial estimation ability in working memory, named the Perceptual Estimation Test (PET). This novel task was designed with three variations that would increase in complexity as they progressed, and each variation would include three trials. Participants were scored on their accuracy performance during the PET. Participants aged 18-25 were recruited from students attending the University of Central …


The Effect Of Temperature And Salinity On Margalefidinium Polykrikoides Group Iii Va, Usa Strain Growth, Eduardo Pérez-Vega, Margaret R. Mulholland, Katherine E. Crider, Kimberly E. Powell, P. Dreux Chappell, Alexander Bochdansky Jan 2025

The Effect Of Temperature And Salinity On Margalefidinium Polykrikoides Group Iii Va, Usa Strain Growth, Eduardo Pérez-Vega, Margaret R. Mulholland, Katherine E. Crider, Kimberly E. Powell, P. Dreux Chappell, Alexander Bochdansky

OES Faculty Publications

Margalefidinium polykrikoides is a cosmopolitan dinoflagellate that blooms in coastal waters. Despite genomic evidence that it belongs to Group III and so closely related to isolates from Puerto Rico, Malaysia, North America, and Central America, M. polykrikoides blooms in the Chesapeake Bay at warmer temperatures and lower salinities than in coastal ecosystems occupied by its closest relatives. In this study, the effect of temperature and salinity on the growth rate and total cell yield of an M. polykrikoides VA culture isolate were examined and compared with environmental observations made during M. polykrikoides blooms in the Chesapeake Bay. M. polykrikoides group …


Revealing Spatiotemporal Neural Activation Patterns In Electrocorticography Recordings Of Human Speech Production By Mutual Information, Julio Kovacs, Dean Krusienski, Minu Maninder, Willy Wriggers Jan 2025

Revealing Spatiotemporal Neural Activation Patterns In Electrocorticography Recordings Of Human Speech Production By Mutual Information, Julio Kovacs, Dean Krusienski, Minu Maninder, Willy Wriggers

Mechanical & Aerospace Engineering Faculty Publications

Background

Spatiotemporal mapping of neural activity during continuous speech production has been traditionally approached using correlation coefficient (CC) analysis between cortical signals and speech recordings. A prior study employed this approach using electrocorticography (ECoG) data from participants who underwent invasive intracranial monitoring for epilepsy. However, CC cannot detect nonlinear relationships and is dominated by the correspondence between periods of silence and of non-silence.

New Method

We introduce the mutual information (MI) measure, which can capture both linear and nonlinear dependencies. We validated CC and MI on the sub-second spatiotemporal brain activity recorded during continuous speech tasks. To refine the results, …


Traction Force Microscopy Using An Epifluorescence Microscope: Experimental Considerations And Caveats, Zaria Booth, Mazen Mezher, Rudra Patel, Venkat Maruthamuthu Jan 2025

Traction Force Microscopy Using An Epifluorescence Microscope: Experimental Considerations And Caveats, Zaria Booth, Mazen Mezher, Rudra Patel, Venkat Maruthamuthu

Mechanical & Aerospace Engineering Faculty Publications

Forces exerted by cells due to their internal contractility play fundamental roles in a host of processes, including adhesion, migration, survival and differentiation. Traction force microscopy (TFM) enables the determination of forces exerted by cells or cell collectives on their environment, which is typically taken to be an extra-cellular matrix (ECM)-coated substrate. Sample preparation for TFM involves the plating of cells onto an environment embedded with fiducial markers. The imaging of these fiducial markers in the presence and absence of the cells then enables calculation of the displacement of localized regions of the environment, and, consequently, the spatial distribution of …


An Analytical Model Of Motion Artifacts In A Measured Arterial Pulse Signal—Part Ii: Tactile Sensors, Md Mahfuzur Rahman, Subodh Toraskar, Mamun Hasan, Zhili Hao Jan 2025

An Analytical Model Of Motion Artifacts In A Measured Arterial Pulse Signal—Part Ii: Tactile Sensors, Md Mahfuzur Rahman, Subodh Toraskar, Mamun Hasan, Zhili Hao

Mechanical & Aerospace Engineering Faculty Publications

This paper, the second of two parts, presents an analytical model of motion artifacts (MA) in measured pulse signals by a tactile sensor, which contains a deformable microstructure sitting on a substrate. While the tissue-contact-sensor (TCS) stack and the sensor are both treated as a 1DOF (degree-of-freedom) system, tissue–sensor contact joins their mass together to form a 1DOF system with springs and dampers on both sides. MA on the sensor substrate causes baseline drift and time-varying system parameters (TVSP) of the TCS stack simultaneously. An analytical model is developed to mathematically relate baseline drift and TVSP to a measured pulse …