Medicine and Health Sciences Commons^™

Evaluation Of Lc-Uv Data For Method Validation, Maeve Scott

Case studies: Digital Education

The module was co-delivered in face-to-face mode to three Science programmes (typically 70 students) in year three, many of whom apply to industries where the learning outcome of the video is a key competency. Analytical methods used in a regulated or accredited testing environment must be validated in line with international guidelines. A science graduate who intends to work in a pharmaceutical or related industry should understand how to interpret test results to demonstrate an analytical method is reliable and fit for purpose. A screen pal video was generated to support an introduction to the theory of method validation delivered …

An Interoperability Framework Across Legacy Emr Systems, Sheena Rogers

Translational Projects (Open Access)

The 21st Century Cures Act (H.R.34 – 114th Congress, 2016) specifies that patients and authorized providers must be able to receive copies of their medical records with standard medical history details upon request. While the data archival system, DRIS (Data Retention Interoperability Solution), has comprehensive patient summary reports centralizing over 100 legacy electronic health records (EHR) with broad data elements, it is not 100% compliant with the upcoming 21st Century Cures Act’s interoperability standards. As a result, patients and providers are not receiving copies of their medical records with all of the required medical history and fields in this new …

Strategies To Improve Nurse Documentation Compliance And Confidence In The Delivery Of Preprocedural Education, Danielle A. Burris

Doctor of Nursing Practice Final Project Abstract

Strategies to Improve Nurse Documentation Compliance and Confidence in the Delivery of Preprocedural Education:

Abstract

Introduction:This project aimed to implement tools to improve preprocedural education compliance between nurses and patients in an interventional radiology department. The secondary aim was increasing staff confidence in providing education, reducing the potential for avoidable harm and adverse procedural-related outcomes. The project was implemented within an interventional radiology department of a healthcare system in the Texas Medical Center, Houston, Texas.

Methodology: The project utilized the Model for Improvement and followed the steps of the Plan-Do-Study-Act cycle to implement change. Strategies included checklists, reminder tools, …

Sox18 Unleashed: Exploring The Transcriptomic Landscape – Differential Gene Expression Analysis Via Rna Seq In Overexpressed Sox18, Van Nguyen, Terry Shackleford, Lori Boies

Posters - 2025

Cancer remains a leading cause of death worldwide, and childhood sarcomas such as Rhabdomyosarcoma (RMS) and Ewing Sarcoma (ES) are particularly aggressive with limited targeted treatment options. Despite advancements in cancer therapies, metastatic sarcomas still have a survival rate below 30%, emphasizing the need for new therapeutic targets. SOX18, a transcription factor has played a role in vascular development and endothelial differentiation, functioning as a key driver of angiogenesis. In cancer, increased SOX18 expression has been linked to dysregulated cell migration, invasion, and therapy resistance mechanisms. However, the extent to which SOX18 influences RMS and ES at the transcriptional level …

Maternal Obesity Alters Antigen-Bound Igg Levels In Breast Milk, G. Sophia Noriega, Andrea Paredes, Emma C. Colins, Elizabeth A. Leadbetter

Posters - 2025

• Maternal obesity is an increasingly prevalent condition worldwide that has been associated with adverse outcomes in offspring, including higher propensity to infection and elevated risk of immune-related disorders like asthma and allergies 1 .

• Breast milk contains a wide variety of immunological components that are essential for neonatal immune development. Among these, it contains immunoglobin G (IgG) immune complexes, which are formed by IgG bound to specific antigens2 .

• These immune complexes have been suggested to play a crucial role in antigen-specific immune response in breastfed infants3 , increasing oral tolerance and asthma prevention 4 .

• …

The Impact Of Employer-Provided Drug/Alcohol Education On Marijuana And Alcohol Use In Young Adults., Sonia Cerrillo, Naomi Ramirez

Posters - 2025

According to the American Society of Addiction Medicine, addiction is a treatable, chronic medical disease involving complex interactions among brain circuits, genetics, the environment, and an individual’s life experiences (1). People with addiction use substances or engage in behaviors that become compulsive and often continue despite harmful consequences. The most common addictions in the United States are alcohol and marijuana (2). In the U.S., 59.277 million people twelve and older have used illegal drugs or misused prescription drugs. Out of the 138.522 million Americans who overdrink alcohol, 28.32 million have an alcohol use disorder (3).

Since alcohol and drug abuse …

Spectroscopic And Electrochemical Properties Of Ugi Adducts Of Isatin, Callah Preti, Erick Y. Morales Orrante

Posters - 2025

• β-lactams are essential structural components of many antibiotics and widely studied due to their biological importance and synthetic versatility.

• The Ugi reaction is a multicomponent reaction involving: • Aldehyde, primary amine, carboxylic acid, and isocyanide.

• Rapidly generates α-acetamido carboxamide derivatives (Ugi adducts). • The study focuses on the synthesis and characterization of two oxindole-based β-lactam derivatives:

• 1-Benzyl-N-(tert-butyl)-2-oxo-3-(2-oxoazetidin-1-yl)indoline-3- carboxamide (4a).

• N-(tert-Butyl)-2-oxo-3-(2-oxoazetidin-1-yl)indoline-3- carboxamide (4d).

• Characterization methods included IR Spectroscopy, UV-Visible Spectroscopy, and X-Ray Crystallography.

• Future work will investigate metal complexation to enhance β-lactam stability, alter electronic properties, and improve biological activity

Examining The Features Of Former Research Regarding Substance Abuse Treatment, Autumn Gonzales

Posters - 2025

“Drug misuse is one of the major social, legal, and publichealth challenges in the modern world” (Nutt et al., 2007). This study explored the characteristics of former research on substance abuse treatment approaches and treatment settings. Past literature showed short-term treatment can be beneficial depending on what works best for the individual and studies have shown short-term treatment has helped individuals with Substance Use Disorder (SUD). However, long-term treatment is the preferred method for individuals as it has a lower chance of relapse. A small systematic review was conducted from which data were coded of former published articles. A frequency …

Evaluation Of Angiogenesis In An Ex-Ovo Chick Chorioallantoic Membrane (Cam) Assay To Study The Mmp9 Gene In Pediatric Cancer Cell Lines, Franchesca Tinacba, Kahlie Hernandez, Terry Jo Shackleford

Posters - 2025

Model organisms are widely utilized in cancer research due to their ability to allow researchers to study biological processes that occur within cancer progression. One model organism that is used is the Chorioallantoic Membrane (CAM) assays. Chicken embryos are a sufficient model that are used to study processes such as angiogenesis, tumor growth, and drug effects. What makes these models useful is due to the cost efficiency, accessibility, and the increased speed the blood vessels can grow. Despite the results, it can be difficult to image the results or monitor the CAM assay. That is why Ex-ovo CAM assays have …

Cd36 Deletion Hampers T-Bet B Cell-Differentiation In R848 Immunized Mice And Hfd Models, Andrea Paredes, G. Sophia Noriega, Carlo Vanz, Emma Collins, Elizabeth A. Leadbetter, Benjamin T. Enslow

Posters - 2025

In states of chronic inflammation, a subset of B cells exquisitely responsive to nucleic acid antigen and expressing the proinflammatory transcription factor T-bet have been found to accumulate1. Depending on the context, these T-bet+ B cells can play both protective and pathogenic roles, from enhancing antiviral defenses to contributing to autoreactive antibody production and exacerbating metabolic disease1,2.

• Recently, our laboratory and others have found that T-bet+ B cells extracted from human or murine tissues exhibit unusually high expression of the class B scavenger receptor and fatty acid translocase CD36.

• As CD36 expression in B cells is generally limited …

The Acute Effects Of High-Intensity Functional Training On Inhibitory Control, Julia Daniel, Amaryllis Rubalcaba, Brianna Valadez

Posters - 2025

High-Intensity Functional Training (HIFT), such as CrossFit®, integrates high-intensity, multi-joint movements and has gained attention for its potential to enhance both physical and cognitive performance. While acute resistance exercise (RE) is known to influence physiological responses like heart rate variability (HRV) and cognitive functions such as inhibitory control, the specific effects of CrossFit®—a structured HIFT program—on cognitive outcomes remain underexplored, particularly when comparing trained CrossFit participants to untrained or non-CrossFit populations. HIFT’s unique combination of cardiorespiratory and muscular stress may uniquely enhance cognitive processing speed and response stability, especially in individuals with chronic CrossFit® experience. However, it is unclear how …

V.O.T.S. Virus Outbreak Tracking System, Izak O. De La Cruz, Elias Ciudad Leon, Van Nguyen, Amy Torres, Enzo Jaques

Posters - 2025

In a post-pandemic world, the need for real-time, accessible disease tracking has never been more critical. While global COVID-19 heat maps were widely utilized during the pandemic, local virus tracking tools have since diminished, leaving a gap in public health awareness.

V.O.T.S. is an interactive application that visualizes real time disease outbreaks through an interactive heatmap, enabling users to track virus trends by county, severity, and timeframe. The system integrates public health data from trusted sources such as the CDC, empowering individuals and healthcare professionals to make informed decisions. In addition, V.O.T.S. enhances accessibility with multilingual support, symptoms assessment, and …

Investigating The Drug Response Of Pdac Cells To Pan-Kras Inhibitor, Jalyn De La Fuente, Yi Xu, Jun Liu, Angel Dominquez, Ava Sanchez, Pei Wang

Posters - 2025

Pancreatic ductal adenocarcinoma (PDAC) is an exocrine pancreatic cancer. It is one of the most lethal types of cancer and is projected to become the second leading cause of cancer-related deaths by 20401 . One major challenge in treating PDAC is drug resistance and the lack of effective treatments. Oncogenic KRAS mutation and loss of function mutation in tumor suppressor genes including P16, TP53, and SMAD4 are found in most PDAC patients. It is unclear whether the different driver mutations can affect the tumor responses to chemo- and targeted therapy. Gemcitabine, a chemotherapy drug, is a cytotoxic agent that has …

Acute Physiological Responses To An Infrared Sauna Blanket Towards Home Based Passive Heat Therapy, Arlene Chaidez, Mia Gonzales, Amaryllis Rubalcaba, Meghan Walls, Rene Barbier

Posters - 2025

Repeated passive heat exposure can improve cardiovascular health outcomes. A novel infrared sauna blanket may enable home-based heat therapy, but these devices are yet understudied. By closely monitoring blood pressure, heart rate, core body temperature, and perceptual responses, it could be determined how a participant's body reacts to the infrared treatment. We found elevated cardiovascular activity in response to the sauna blanket, similar to that observed during moderate-intensity exercise. Therefore, the infrared sauna blanket may have potential for inducing long-term cardiovascular adaptations and become an accessible and costeffective way of treating/preventing chronic illness.

Quality-Of-Care Measures For Cardio-Oncology: An Ic-Os And Acc Cardio-Oncology Leadership Council Perspective, Vijay U Rao, Anita Deswal, Daniel Lenihan, Susan Dent, Teresa Lopez-Fernandez, Alexander R Lyon, Ana Barac, Nicolas Palaskas, Ming Hui Chen, Hector R Villarraga, Diego Sadler, Courtney M Campbell, Kerry Skurka, Matt J Wagner, Matthias Totzeck, Kathryn J Ruddy, Paul Heidenreich, Randal Thomas, Daniel Addison, Sarju Ganatra, Richard Cheng, David Reeves, Arjun K Ghosh, Joerg Herrmann

Children’s Nutrition Research Center Staff Publications

This document serves as a perspective on quality assessments in the discipline of cardio-oncology. We aim to define the current landscape, identify needs for quality and outcome improvements, and propose a roadmap for establishing viable metrics to improve patient care. Specifically, this document: 1) addresses the current lack of measurable high-quality metrics in cardio-oncology and their implications; 2) highlights needs and topic-specific barriers; 3) illustrates the process and application of a measurable quality metric; and 4) provides a framework to demonstrate measurable value for the growing population of patients with cancer and cardiovascular diseases.

Demographic Clinical Trial Diversity Assessment Methods: Use Of Real-World Data, Hua Chen, Nnadozie Emechebe, Sudeep Karve, Leon Raskin, Jailene Leal, Ning Cheng, Wendy Sebby, Kim Ribeiro, Samuel Crawford

Children’s Nutrition Research Center Staff Publications

Diversity in clinical trials is defined by the inclusion of clinical trial participants from various demographic groups that are representative of the broader population impacted by a disease state. Diversity in clinical trials is critical in identifying potential differences in safety and efficacy of treatments across races, ethnicities, ages, sexes, or other variables. In the United States, clinical trial diversity is often benchmarked against US Census data, which may limit the representativeness of patient demographics in clinical trials. Disease-specific, demographic estimates from real-world data (RWD) can facilitate benchmarking of clinical trials, support trial enrollment and the development of trial diversity …

Academic Productivity At Orthopaedic Surgery Sports Medicine Fellowship Programs In The United States Has A Weak Positive Correlation With Nonresearch Lifetime Industry Earnings, Benjamin Miltenberg, William Johns, Anthony Baumann, Faheem Pottayil, Bradley Richey, Albert Anastasio, Kempland Walley, Christopher Dodson, Sommer Hammoud

Rothman Institute Papers

PURPOSE: To characterize the relationship between academic productivity, as defined by the h-index, and industry payments for fellowship-trained sports medicine surgeons in faculty positions at sports medicine fellowships.

METHODS: The American Orthopaedic Society for Sports Medicine fellowship directory was used to create a comprehensive list of all fellowship programs nationwide. Fellowship websites were then reviewed to generate a list of the teaching faculty associated with each program. Total nonresearch lifetime earnings were obtained from the Centers for Medicare & Medicaid Services website. Academic productivity of each fellowship faculty was assessed via the h-index. Frequency counts and other descriptive statistic measures …

Medical Faculty Perceptions Of Faculty Development And Its Impact On Teaching Quality, Melinda Turner

Other Scholarly Works

American Association of Colleges of Osteopathic Medicine Educating Leaders 2025 Conference Session Presentation. School/ College: Session: D22.7 - Medical Ed Training Program: Concurrent Oral Session Abstract Theme: Empowering Educators: Professional Development, Leadership, and Scholarship Presentation Type: Research Audience Track: UME - Pre-Clinical Education Brief Description Medical faculty often transition from clinical practice to teaching roles with limited pedagogical training, impacting the quality of medical education. This study addresses the need for effective faculty development programs by examining faculty perceptions of their impact on teaching quality, a critical aspect of medical education. This research investigates the effectiveness of a faculty development …

Understanding The Challenges And Opportunities For Orthopedic Manual Physical Therapy In Filipino Physical Therapy Practice: An Exploratory Survey, Oliver Ang, Lily Ann Bautista, Maria Carmela Gerella, Roly Dimol, Arvie Vitente, Ulysses Juntilla, Michael Brian Gasidan

Philippine Journal of Physical Therapy

Introduction: Orthopedic manual physical therapy (OMPT) is renowned for its positive biophysical and psychosocial effects, making it an important tool in clinical practice. Although OMPT has long been a stable intervention used in developed countries, its adoption has spiked in developing countries, including the Philippines. Despite this progress, no comprehensive study has explored the factors that may hinder or enable Filipino physical therapists (PTs) from utilizing OMPT into their daily clinical practice. The aim of this study was to conduct a thorough behavioral analysis to determine Filipino PTs' capabilities, opportunities, and motivations for using orthopedic manual therapy in their clinical …

Lessons From The Picu, Lia M. Smerina

be Still

No abstract provided.

Sacred Oath Of Healing - Volume 9

be Still

No abstract provided.

The Hidden Scars Of Healing, Amanda Almeida

be Still

A photograph collection of Mark's unique road to healing, and a medical narrative.

The Essence Of Resilience, Evelyn Echevarria Cruz

be Still

No abstract provided.

Cultivating Compassionate And Inclusive Care For People With Disabilities, Evelyn Echevarria Cruz, Aila Cordero, Maria Fioletova, Amanda Escudero

be Still

The disparity between physicians' preparedness to treat people with disabilities (PWD) and the prevalence of disabilities is a critical healthcare issue. The 2022 Behavioral Risk Factor Surveillance System reported that over 25% of U.S. adults have a disability, yet many healthcare providers feel unprepared. A poll found that only 40.7% of 714 physicians were confident in providing quality care to PWD, while 61% of 600 surveyed PWD indicated that their providers needed more training. Additionally, only 36% of medical schools included disability education in their curricula, often focusing on brief simulations rather than immersive experiences. To effectively address the diverse …

Know Your Limits: The Story Of How I Learned To Listen To My Body, Elena Silverstein

be Still

No abstract provided.

The Healing Power Of A Welcomed Hug, Tara Mckenna

be Still

No abstract provided.

Putting Myself First, Nicholas E. Doberstein

be Still

No abstract provided.

The Circle Of Life And Care, Isabel M. Vera Machado

be Still

As a first-year medical student on the osteopathic path, my art is a reflection of my journey to balance creativity and the principles of holistic care. Osteopathic medicine’s focus on treating the whole person—mind, body, and spirit—aligns closely with my approach to art, which aims to capture the connections between humanity, healing, and empathy.

Through my work, I explore themes of care, connection, and the values I hope to uphold as a future physician. Whether it’s through symbolic imagery or simple, heartfelt compositions, my art reflects the importance of compassion and the human connection in both medicine and life.

For …

An Oath Fulfilled, Fatima Bawaney

be Still

This poem explores the sacred oath of healing as it relates to a physician-patient relationship.

Cultural And Religious Perspectives On Suicide And Healing, Arielle Friedman

be Still

This essay is built off of a paper I wrote in a college global health course on culture and mental illness. I have always been fascinated by cultural interpretations of illness & believe that as a future physician, it is my responsibility to educate myself and others on the complex interplay between religious ideologies & recognition/management of biological disease in order to provide appropriate patient-centered care.