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Role Of Hospital Leadership In Pandemic Preparedness: Experience At A Tertiary Hospital In Kenya During The Covid-19 Pandemic, Lucy Wangari, William Macharia, Benjamin Wachira, Jemimah Kimeu, Boniface Mativa, Lukoye Atwoli

Emergency Medicine, East Africa

Introduction Pandemic preparedness refers to being ready for, responding to and recovering from public health crises, and is integral for health security. Hospital leadership is a critical building block of an effective healthcare system, providing policy, accountability and stewardship in a health crisis.

Objectives and methods We aimed to describe the leadership and governance structures put in place at the Aga Khan University Hospital, Nairobi, a private not-for-profit tertiary healthcare facility, following the COVID-19 pandemic. We reviewed over 200 hospital documents archived in the COVID-19 repository including those received from the Kenya Ministry of Health, emails, memos, bulletins, meeting minutes, …

Future Directions For Emergency Medical Services Development In Low- And Middle-Income Countries, Peter Delaney, Jon Moussally, Benjamin Wachira

Emergency Medicine, East Africa

The lack of prehospital care access in low- and middle-income countries is one of the greatest unmet needs and, therefore, one of the most urgent priorities in global health. Establishing emergency medical services in low- and middle-income countries poses significant challenges and complexities, requiring solutions tailored to prevailing conditions, informed by needs assessments, and adapted to meet local demands in a culturally appropriate and sustainable manner. In areas without existing emergency medical services, patients must rely on informal networks of untrained bystanders and community members to provide first aid and transport to definitive care. Since 2005, training lay first responders …

Exploring The Functional Significance Of A Yap1 Missense Variant Of Uncertain Significance In Caenorhabditis Elegans, Nathan Jones

Theses

Polycystic ovary syndrome (PCOS) is a complex disorder with various implications, such as polycystic ovaries, visceral obesity, and increased risk of cancer. YAP1 was recently identified as a gene of interest in the development of PCOS. Researchers have established that single nucleotide variants in YAP1 are likely to play a role in PCOS development. This project aims to provide insight into the potential impact of a YAP1 variant of uncertain significance (VUS). Studies in C. elegans have established yap-1 as a nematode ortholog for human YAP1. A YAP1 VUS was identified through ClinVar, YAP1 c.1015A>G (p.Asn339Asp). Evolutionary conservation …

The Key Elements And Driving Paths Of Digital Empowerment For The Efficient Construction Of The Rural Medical And Health Service System: Based On 28 Cases Through Fsqca, Liqing Li, Ming Yu

Journal of Scientific Information Research

[Purpose/significance]This paper explores the linkage effect and improvement path of technology-organization-environment antecedents on the efficient construction of digital empowerment rural medical and health service system, in order to accelerate the research progress of digital construction of rural medical and health service. [Method/process]Based on the technology-organization-environment (TOE) framework and China's real-life scenarios, this paper constructs a theoretical analysis framework for the efficient construction of digital empowerment rural medical and health service system, Using the method of fuzzy set qualitative comparative analysis, this paper takes the rural areas of 28 provinces (autonomous regions and municipalities directly under the central government) in China …

Call Me Dr Ishmael: Trends In Electronic Health Record Notes Available At Emergency Department Visits And Admissions, Brian W Patterson, Daniel J Hekman, Frank J Liao, Azita G Hamedani, Manish N Shah, Majid Afshar

Faculty, Staff and Student Publications

OBJECTIVES: Numerous studies have identified information overload as a key issue for electronic health records (EHRs). This study describes the amount of text data across all notes available to emergency physicians in the EHR, trended over the time since EHR establishment.

MATERIALS AND METHODS: We conducted a retrospective analysis of EHR data from a large healthcare system, examining the number of notes and a corresponding number of total words and total tokens across all notes available to physicians during patient encounters in the emergency department (ED). We assessed the change in these metrics over a 17-year period between 2006 and …

Multicountry Spread Of Influenza A(H1n1)Pdm09 Viruses With Reduced Oseltamivir Inhibition, May 2023-February 2024, Mira C Patel, Ha T Nguyen, Philippe Noriel Q Pascua, Rongyuan Gao, John Steel, Rebecca J Kondor, Larisa V Gubareva

Faculty, Staff and Student Publications

Since May 2023, a novel combination of neuraminidase mutations, I223V + S247N, has been detected in influenza A(H1N1)pdm09 viruses collected in countries spanning 5 continents, mostly in Europe (67/101). The viruses belong to 2 phylogenetically distinct groups and display ≈13-fold reduced inhibition by oseltamivir while retaining normal susceptibility to other antiviral drugs.

Nsu Kpcom Link - Summer 2024 - Volume 3.2, Nova Southeastern University

NSU Florida Link Newsletter

No abstract provided.

The Hidden Impact Of Sociocultural Determinants In Adolescence, Lauren B. Robins, Nicholas Schmoyer, Atiya Smith, Krystal L. Clemons, Jill Kivikoski

Journal of Human Services Scholarship and Interprofessional Collaboration

This study, guided by the Social Determinants of Health framework and Social Ecological Model, examined how SDOH impact the presence of anxiety during adolescence. This study set out to understand what sociocultural determinants predict anxiety, using the 2018 National Survey of Children’s Health dataset. The analysis included a logistic regression to determine the predictability of SDOH on anxiety in adolescence. The results indicated that various SDOH are significant predictors of anxiety, while also indicating that the absence of adverse SDOH predicts the lack of anxiety. Further, unique findings related to race/ethnicity, age, and gender set the stage for additional research …

Analyzing The Predicted Impact Of Published Scn5a Variants In Juvenile-Onset Sick Sinus Syndrome, Snekha Rajasandra, Aleksandra Foksinska, Camerron Crowder, Matthew Might

Expo Student Presentations

2024 Summer Expo Poster Presentation

• Works in Progress

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Mixed-Methods Assessment Of Farmworkers’ Perceptions Of Workplace Compliance With Worker Protection Standards And Implications For Risk Perceptions And Protective Behaviors, Carly Hyland, Lisa Meierotto, Rebecca L. Som Castellano, Cynthia L. Curl

Public and Population Health Faculty Publications and Presentations

Introduction: The Environmental Protection Agency (EPA)’s Worker Protection Standards is the primary set of legislation aimed at protecting farmworkers from occupational pesticide exposure in the United States. Previous studies suggest that worker adoption of Pesticide Protective Behaviors (PPBs) promoted by WPS is associated with lower urinary pesticide concentrations. However, adoption of PPBs is often outside of the control of individual farmworkers and dependent on workplace factors such as employer provisioning of Personal Protective Equipment (PPE) and access to trainings/resources.

Methods: We conducted a mixed-method study including urinary pesticide biomonitoring, surveys, and interviews with 62 Latinx farmworkers in southwestern Idaho from …

Psychosocial And Mental Health Challenges Facing Perinatally Hiv-Infected Adolescents Along The Kenyan Coast: A Qualitative Inquiry Using The Socioecological Model, Stanley W. Wanjala, Moses Nyongesa, Stanley Luchters, Amina Abubakar

Institute for Human Development, East Africa

Background: The advent of antiretroviral therapy has led perinatally HIV-infected (PHI) adolescents to live long, fulfilling lives through lifelong treatment. However, there is limited knowledge about the lived experiences and psychosocial and mental health challenges faced by PHI adolescents in sub-Saharan Africa, where 80% of PHI adolescents reside. To address this gap, we adapted the socioecological model to investigate the challenges and lived experiences of PHI adolescents in rural coastal Kenya.

Methods: Between October and November 2018, a sample of 40 participants (20 PHI adolescents and their 20 primary caregivers) participated in a qualitative study using an H-assessment data collection …

Promoting Mental Wellness In First-Generation College Students, George Cardenas

Occupational Therapy Student Capstones

No abstract provided.

Un-Barre-D: Decreasing Barriers To Participation For Individuals With Parkinson’S Using Ballet, Lauren Jew

Occupational Therapy Student Capstones

No abstract provided.

Amplifying Success: Providing Ot-Based Support For Deaf And Hard Of Hearing Children In The School Setting, Liana Mae Atizado

Occupational Therapy Student Capstones

No abstract provided.

The Harding University Speech Clinic As A Community Outreach Program In White County, Melaney Binkley

McNair Scholars Research

A university speech clinic provides, at no cost to clients, more selective, limited speech and language services by a student clinician in the Communication Sciences and Disorders program under the supervision of a certified speech-language pathologist (SLP). A private speech clinic requires certified speech-language pathologists and assistants. The purpose of this study was to analyze the Harding University Speech Clinic’s client population, particularly in terms of socioeconomic status, since the city in which the university is located has a higher average poverty rate than the state. Additionally, the study sought to measure the level of client satisfaction with the services …

July 2024, Humayun Islam

PMI Newsletter

No abstract provided.

Multi-Omic Single-Cell Integration For Understanding T Cell Responses In Acute Myeloid Leukemia, Poonam Desai

Dissertations and Theses (Open Access)

In recent years, translational initiatives have gained significant traction within the medical community. Clinical parameters alone have been insufficient to fully understand the intricate mechanisms governing patient responses to disease and therapy. Additionally, single-cell technologies have rapidly advanced to a point where generation of large patient-based datasets is financially and logistically feasible. The integration of clinical information with multi-omic single-cell technologies enables the formation of data-driven hypotheses pertaining to the mechanisms of disease progression and therapeutic resistance. Acute Myeloid Leukemia (AML) is a rapidly-progressing cancer of the bone marrow with poor prognoses and dismal outcomes. Of the adult patients that …

Dying With Dignity: How Can We Deliver Values-Concordant End-Of-Life Care For Immigrant Patients In The United States?, Khushi Kohli, Erin Jay G. Feliciano, Nishwant Swami, Aditya Narayan, Tej A. Patel, Bhav Jain, Puneeth Iyengar, Julie Kanevsky, Paul L. Nguyen, Edward Christopher Dee

Ateneo School of Medicine and Public Health Publications

No abstract provided.

Exploring Serum Α-Synuclein And Its Autoantibodies In Essential Tremor: Implications For Diagnosis And Symptom Correlations, Ali Shalash, Ahmed Doma, Mai Barakat, Eman Hamid, Mohamed Salama

Faculty Journal Articles

There is no definite biomarker for confirming the diagnosis of essential tremor (ET) or differentiating it from other diseases, particularly Parkinson's disease. The present study aimed to investigate the serum levels of the α-synuclein protein (α-syn) and its autoantibodies in patients with ET compared with healthy controls and its relation to motor and non-motor symptoms in patients with ET. Serum α-syn and its autoantibodies were measured in 32 patients with ET and 32 age- and sex-matched controls. Both groups were assessed using the non-motor symptoms scale, MoCA, Beck Depression Inventory, Hamilton Anxiety Rating Scale, and the Short Form 36 Health …

Dose-Dependent Effects Of Dnmt3a In An Inducible Murine Model Of Krasg12d-Driven Leukemia, Jason H Rogers, Allison Rosen, Jaime M Reyes, Shamika Ketkar, Shannon E Conneely, Rohit Gupta, Luibin Yang, Matthew B Miller, Geraldo Medrano, Rogelio Aguilar, Nneka Uchenda, Margaret A Goodell, Rachel E Rau

Children’s Nutrition Research Center Staff Publications

DNMT3A mutations are frequently found in clonal hematopoiesis and a variety of hematologic malignancies including acute myeloid leukemia (AML). An assortment of mouse models have been engineered to explore the tumorigenic potential and malignant lineage bias due to loss of function of DNMT3A in consort with commonly co-mutated genes in myeloid malignancies such as Flt3, Nras, Kras, and c-Kit. We employed several tamoxifen-inducible Cre-ER^T2 murine model systems to study the effects of constitutively active Kras^G12D-driven myeloid leukemia (Kras) development together with heterozygous (3aHet) or homozygous Dnmt3a deletion (3aKO). Due to the rapid generation of …

Sw 1010: Finding And Using Research (Library Module), Usu Libraries

All E-Learning Resources

Attention: As of 2026 updated versions of this module will no longer be available on Digital Commons. Please contact [email protected] for more information.

In this module you'll learn:

• What a peer-reviewed source is and why you'll want to use them for your research assignment
• How to avoid paywalls and get full access to peer reviewed sources for free
• How to break your research topic into keywords for database searching
• How to cite your sources using APA citation style

Examining Enrollment & Engagement In A Hospital-Based Violence Prevention Intervention Study At A Level 1 Trauma Center, Leigh Frederick

Electronic Theses and Dissertations

BACKGROUND: Violence is a significant healthcare issue that affects the health and well-being of individuals, families, and communities. Violence prevention and intervention programs are a powerful way to stop the revolving door of violent injury in our hospitals and communities. The Health Alliance for Violence Intervention (HAVI), develops and connects violence intervention programs, promotes equity for victims of violence globally, and is dedicated to engaging patients during the window of opportunity when they are recovering in the hospital after a violent injury to reduce the chance of retaliation (related to the injury) and recurrence. A small body of research shows …

The Effectiveness Of Nurse Assistants Training Programme On Safe Motherhood: A Study On Bhutanese Nurse Assistants, Jureerat Kijsomporn, Nualyai Pitsachart, Phayong Thepaksorn, Ling Shing Wong, Vinodhkumar Ramalingam, Voon Wan Niu

Journal of Asian Midwives (JAM)

Background: This study aims to investigate the ability of nurse assistants in midwifery care in Bhutan to apply their knowledge and skills after attending the training programme.
Methods: A qualitative methodology was utilized in this study, in-depth interviews using a semi-structured interview guide questionnaire with five nurse assistants, three district health officers, and two medical doctors from hospitals. The interviews (n=10) were conducted on-site at basic health units in URA and Tang, Bhutan.
Results: The data analysis of their perceptions yielded three major categories: (1) Confirmability, the Quality of knowledge and skills of the program; (2) Credibility, Effectiveness, and comprehensiveness …

Balancing Life After Spousal Loss: A Cross-Sectional Study Investigating The Mental Well-Being And Life Satisfaction Of Martyrs’ Wives, Mehreen Aslam, Ambreen Tharani, Yasmin Parpio, Rafat Jan

Journal of Asian Midwives (JAM)

Background: The wives who have lost their spouses in conflict zones are known as martyrs’ wives. After sacrificing the martyrs’ lives, their wives not only face the traumatic experience of losing their loved ones, but this loss may substantially affect their physical, socioeconomic, and emotional health. It may serve as a "vulnerability factor," raising the risk of depression.
Objective: To assess the levels of life satisfaction and mental well-being within the wives of martyrs residing in Karachi, Pakistan.
Methodology: A descriptive cross-sectional study was conducted to assess the mental well-being and life satisfaction of martyrs’ wives living in Karachi Pakistan. …

Determinants Of Underutilization Of Maternal Health Services In Anc Clinics In Lmics: A Narrative Review, Jonathan Johnson, Rubeka Mansha, Abeer Musaddique

Journal of Asian Midwives (JAM)

Background: Antenatal care (ANC) is critical for achieving Sustainable Development Goals (SDG) 3.1 and 3.2, aiming to reduce the global maternal mortality ratio to less than 70 per 100,000 live births by 2030, and to decrease neonatal and under-5 mortality rates. Despite its importance, approximately 830 women die daily from preventable pregnancy and childbirth causes, predominantly in low-resource settings.
Methods: The study conducted a comprehensive literature search from January 1, 2009, to December 30, 2020, focusing on delayed initiation of ANC in low- and middle-income countries (LMICs). The search used multiple databases and included observational research and Demographic …

Post-Partum Hemorrhage (Pph) Management In Emergency, Learning Experience, Gul Raihan

Journal of Asian Midwives (JAM)

No abstract provided.

Complicated Home Delivery: A Real Story, Nusrat Jahan

Journal of Asian Midwives (JAM)

No abstract provided.

Completion Of Pembrolizumab In Advanced Non-Small Cell Lung Cancer—Real World Outcomes After Two Years Of Therapy (Copilot), Andrew Fantoni, Lydia Warburton, Benjamin Solomon, Marliese Alexander, Meghana Maddula, Lauren Julia Brown, Ines Pires Da Silva, Adnan Nagrial, Farah Abu Al-Hial, Malinda Itchins, Nick Pavlakis, Samantha Bowyer

Research outputs 2022 to 2026

Background: Seminal trials with first-line pembrolizumab for metastatic non-small cell lung cancer (NSCLC) mandated a maximum two-years treatment. We describe real-world outcomes of a multi-site Australian cohort of patients who completed two-years of pembrolizumab. Methods: Retrospective data were collected from the national AUstralian Registry and biObank of thoRacic cAncers (AURORA). Primary endpoints were progression rate post pembrolizumab discontinuation; and progression free survival (PFS). Local treatment of oligoprogressive disease during pembrolizumab was allowed. Results: A total of 71 patients from six centers, median age 66.0 years, 49% male and 90% ECOG ≤ 1 were identified. Patients were Caucasian (82%) or Asian …

The Experiences And Perceptions Of Healthy Siblings Of Children With A Long-Term Condition: Umbrella Review, Julie Blamires, Mandie Foster, Shayne Rasmussen, Maggie Zgambo, Evalotte Mörelius

Research outputs 2022 to 2026

Problem: The lives of healthy siblings living with a sibling with a long- term condition are often shaped by the family, type of illness, length of illness, age of the child, caregiver demands, and support provided to the family, ill sibling, and healthy sibling. While the experiences of healthy siblings are documented in the literature by parent proxy, literature on healthy siblings self-reported experiences of living with a sibling who has a long-term condition remains scarce. Purpose: This umbrella review aims to synthesize reviews on the self-reported experiences of healthy siblings of children living with a sibling who has a …

Antenatal Care Utilisation And Receipt Of Its Components In Nigeria: Assessing Disparities Between Rural And Urban Areas—A Nationwide Population-Based Study, Emmanuel O. Adewuyi, Asa Auta, Mary I. Adewuyi, Aaron Akpu Philip, Victory Olutuase, Yun Zhao, Vishnu Khanal

Research outputs 2022 to 2026

Introduction Antenatal care (ANC) is crucial for positive pregnancy outcomes, but it is underutilised in Nigeria, suggesting unmet needs, and potentially contributing to the country’s high burden of maternal and neonatal mortalities. This study comprehensively assesses ANC utilisation and receipt of its components in Nigeria, focusing on disparities between rural and urban areas. Methods We used the data disaggregation approach to analyse the Nigeria Demographic and Health Survey 2018. We estimated ANC utilisation, assessed the receipt of ANC components, and identified factors associated with eight or more (≥ 8) ANC contacts nationally and across rural and urban residences. Results Nationwide, …