Medicine and Health Sciences Commons^™

Prep And Intimate Partner Violence Among Gay, Bisexual, And Other Men Who Have Sex With Men: A Scoping Review Of The Literature, Swarnali Goswami Ph.D., Joanne Canedo Pharm.D., Cynthia Siddique B.S., Erin Holmes Pharm.D., Ph.D., Marie Barnard Ph.D.

Faculty and Student Publications

Intimate Partner Violence (IPV) continues to be a serious public health concern, impacting nearly affecting diverse communities worldwide. Approximately one in three men experience sexual violence, physical violence, or stalking by an intimate partner in their lifetime.1 Men who have sex with men (MSM) are a particularly vulnerable population, facing unique challenges in the context of both IPV and HIV prevention. MSM experience disproportionately high rates of IPV and remain at an elevated risk of HIV transmission, making them a critical target group for research and intervention efforts.2,3 In recent decades, significant strides have been made in advancing the understanding …

Transforming Perspectives: Identifying And Addressing Disparities In Sexual Health Education In Occupational Therapy Education Programs, Devon C. Wilson

MOT Student Capstones

This capstone project aims to address the lack of sexual health education in Occupational Therapy (OT) curricula and improve OT practitioners' ability to address sex and sexuality in 5 their practice. The research sought to understand the practices and attitudes of OT educators and educational programs in the United States concerning sexual health and sexuality within their curriculum. The study employed a survey-based approach, gathering data from a diverse group of OT educators and program directors through an online platform before and after participating in an educational presentation on the subject matter. The results revealed positive views of sex and …

Reduce Extended Length Of Stay By Reducing In-Hospital Falls, Norberto Benitez

Master's Projects and Capstones

Abstract

Problem: Every year, there are many in-hospital falls (IHFs). Nationally there are between 700,000 to 1 million falls recorded each year. Hospital falls financially burden our healthcare industry, costing approximately 34 billion annually. Context: In a local hospital in Northern California, Marin County, the microsystem has had an extraordinary number of in-hospital falls (IHFs). To date (June 2023), 13 falls have been recorded thus far; the microsystem is on track to beat the previous year's record number of 21 falls in a calendar year. Interventions: The MSN–CNL student proposed re-educating staff, resetting expectations, and reestablishing workflow. We also sought …

Awareness, Acceptance, And Equanimity: Relationships Between Trait Mindfulness, Stress, And Blood Pressure, Gabrielle Renee Chin

Theses and Dissertations

Hypertension (HTN) is associated with stress and unhealthy emotion regulation. Mindfulness-based interventions (MBIs) are said to help address stress-related diseases like cardiovascular disease by impacting stress and emotion regulation, yet studies of MBIs on cardiovascular health show inconsistent findings. Limited research has examined the basic links between trait mindfulness and cardiovascular health, leaving the active components of MBIs in this context unclear. Therefore, the current study examined the relationship between trait mindfulness and blood pressure (BP) in individuals with pre-hypertension (pre-HTN). Latent variables representing two conceptualizations of trait mindfulness -Monitor and Accept Theory (MAT) and Equanimity- were calculated using facets …

What Effect Does Flexible Work Arrangements Have On Efficiency And Job Satisfaction In Medical Dosimetry?, Michelle Walters

Masters Projects

Abstract

The purpose of this research study is to determine new trends in the medical dosimetry profession that relate to when and where work is being completed. It is also of interest to understand efficiencies within radiation oncology departments as well as how medical dosimetrists work arrangements impact job satisfaction. A voluntary survey of current medical dosimetrists was conducted which asked close-ended questions about simulation to treatment time frames, employment type, hours worked, departmental efficiency and perceived job satisfaction. It was established that the resulting 185 responses provided statistically significant results. Greater than half of participants answered yes to either …

Analisis Faktor-Faktor Yang Berhubungan Terhadap Keselamatan Di Tempat Kerja Pada Pt. X Semasa Pandemi Covid-19, Muhammad Faqih Hartono, Fatma Lestari

National Journal of Occupational Health and Safety

PT X Unit Citeureup is the largest cement manufacturing industrial plant in the world. The industrial processes in PT X Unit Citeureup involve a variety of processes, materials, and hazardous works. Thus, the work process in it causes a lot of occupational safety and health risks. In addition, at this time PT X Unit Citeureup is also facing the challenges of the COVID-19 pandemic just like other industries. This situation can have a negative impact on both employees and management of PT X Unit Citeureup. Based on this situation, the establishment of safety in the workplace is something that must …

Analisis Hubungan Faktor Fisik Dan Individu Terhadap Prevalensi Keluhan Musculoskeletal Disorder (Msds) Pada Pekerja Cv Bengkel Otomotif Tahun 2022, Hamzah Fansuri Fajri, Robiana Modjo

National Journal of Occupational Health and Safety

Complaints of musculoskeletal disorders (MSDs) in general can occur due to contraction or excessive loading of muscles or bones. One example of an activity that can trigger the incidence of musculoskeletal disorders (MSDs) is manual material handling work. Manual material handling work is still commonly found in the work done at CV Bengkel Otomotif. This study focuses on looking at the relationship between physical and individual variables with complaints of musculoskeletal disorders (MSDs) in CV Bengkel Otomotif workers. This research is a cross-sectional study with quick exposure check and nordic body map instruments. Of the 60 workers who became respondents …

Improving Peripheral Nerve Regeneration Through Rehabilitation And Biomaterial-Based Drug Delivery Strategies, Yunfan Kong

Theses & Dissertations

Peripheral nerve injury (PNI) is a common problem worldwide, with trauma being a common cause. PNI can lead to loss of sensory and motor functions, chronic neuropathic pain, and mental health issues, significantly impacting patients' family life, work, and social situation. Recent studies revealed that beyond the topical injury site at peripheral nerves, PNIs can also induce dysfunctions in the central nervous system (CNS) by causing maladaptive plasticity, which will result in exaggeration and exacerbation of the pathological condition caused by primary injuries. The common therapy strategies for PNI treatment are using sutures, nerve autografts or conduits in cases requiring …

Role Of Hand Hygiene In The Prevention Of Central Line-Associated Bloodstream Infection In Intensive Care Unit Patients: A Benchmark Project, Meliana Amazan

MSN Capstone Projects

CLABSI (Central Line Associated Blood Stream Infection) is one of the most common hospital-acquired infections in the ICUs (Intensive Care Unit). Not only it is cost prohibitive, but it also prolongs hospitalization. However, it is avoidable. This condition needs to be reviewed to improve patients’ outcomes in the ICUs. This project aims to decrease or eliminate the incidence of CLABSI among ICU patients through proper and mindful hand hygiene. Healthcare providers should be aware of the different care bundles that contribute to decreasing CLABSI and be able to apply them correctly. Articles were searched on different databases such as Cochrane …

Gambaran Kejadian Computer Vision Syndrome Dan Faktor Risikonya Pada Mahasiswa Fkm Ui Di Masa Pandemi Covid-19, Rahadian Muhamad Shadik, Baiduri Widanarko

National Journal of Occupational Health and Safety

Due to the Covid-19 pandemic, many activities that were previously carried out offline have turned into online, including the education sector. This condition increased the use duration of electronic devices with digital screens/VDT, especially among students. It is one of the risk factors for Computer Vision Syndrome. Apart from duration, several risk factors are also associated with Computer Vision Syndrome. The aims of this study are to see an overview of Computer Vision Syndrome incidence and analyze the relationship between Computer Vision Syndrome incidence and its risk factors in regular (S1) and postgraduate (S2) students, FKM UI during the Covid-19 …

Feasibility And Value Of Genomic Profiling In Cancer Of Unknown Primary: Real-World Evidence From Prospective Profiling Study, Ryan W Huey, Aakash Tushar Shah, Honey V Reddi, Priyadarsini Dasari, James T Topham, Hyunsoo Hwang, Nishat Dhillon, Anneleis Willett, Brandon G Smaglo, Jeannelyn S Estrella, Asif Rashid, Aurelio Matamoros, Michael J Overman, Linda Choquette, Greg Omerza, Kevin Kelly, Xuemei Wang, Jonathan M Loree, Jens Rueter, Gauri R Varadhachary, Kanwal Raghav

Faculty, Staff and Student Publications

Real-world evidence regarding the value of integrating genomic profiling (GP) in managing cancer of unknown primary (CUP) is limited. We assessed this clinical utility using a prospective trial of 158 patients with CUP (October 2016-September 2019) who underwent GP using next-generation sequencing designed to identify genomic alterations (GAs). Only 61 (38.6%) patients had sufficient tissue for successful profiling. GAs were seen in 55 (90.2%) patients of which GAs with US Food and Drug Administration-approved genomically matched therapy were seen in 25 (40.9%) patients. A change in therapy was recommended and implemented (primary endpoint of the study) in 16 (10.1%) and …

A Comprehensive Report Of Intrinsically Disordered Regions In Inherited Retinal Diseases, Karen E Lee, Jose S Pulido, Mariana M Da Palma, Rebecca Procopio, Robert B Hufnagel, Margaret Reynolds

2020-Current year OA Pubs

BACKGROUND/PURPOSE: A comprehensive review of the degree of disorder in all genes in the Retinal Information Network (RetNet) Database is implicated in inherited retinal diseases (IRDs). Their association with a missense variation was evaluated.

METHODS: IRD genes from RetNet were included in this study. Publicly available data on the genome aggregation database (gnomAD) were used to analyze the number of total and pathogenic missense variants. Metapredict, an accurate and high-performance predictor that reproduces consensus disorder scores, was used to calculate disorder.

MAIN OUTCOME MEASURES: The main outcome measures were percent disorder, percent pathogenicity, number of total missense variants, and percent …

Terror Management And The News: An Exploration Into The Effects Of Framing On Mortality Salience, Peter Montwill

Masters Theses, 2020-current

The present study explores the link between Terror Management Theory and the use of its principles within news media. Political news media in the digital age undergoes a variety of framing effects, more specifically episodic and thematic frames of stories. To induce mortality salience, college-aged participants were presented with stories framed from the perspective of an individual’s experience or a general theme of experiences regarding the controversial pro-life topic and a non-controversial hiking topic. These stories are presented in the style of Instagram posts to mirror how college-aged people consume news media. The stories also contain wording designed to induce …

Successful Treatment Of Non-Langerhans Cell Histiocytosis With The Mek Inhibitor Trametinib: A Multicenter Analysis, Ashley Aaroe, Razelle Kurzrock, Gaurav Goyal, Aaron M Goodman, Harsh Patel, Gordon Ruan, Gary Ulaner, Jason Young, Ziyi Li, Derek Dustin, Ronald S Go, Eli L Diamond, Filip Janku

Faculty, Staff and Student Publications

Erdheim-Chester disease (ECD) and Rosai-Dorfman disease (RDD) are rare non-Langerhans cell histiocytoses (non-LCHs), for which therapeutic options are limited. MAPK pathway activation through BRAFV600E mutation or other genomic alterations is a histiocytosis hallmark and correlates with a favorable response to BRAF inhibitors and the MEK inhibitor cobimetinib. However, there has been no systematic evaluation of alternative MEK inhibitors. To assess the efficacy and safety of the MEK inhibitor trametinib, we retrospectively analyzed the outcomes of 26 adult patients (17 with ECD, 5 with ECD/RDD, 3 with RDD, and 1 with ECD/LCH) treated with orally administered trametinib at 4 major US …

Analisis Keluhan Non-Auditory Pada Pekerja Bagian Operasi Yang Terpajan Kebisingan Di Unit 5-7 Perusahaan Pembangkit Listrik Pt X Tahun 2022, Aisyah Raini Azzahra Putri, Mila Tejamaya

National Journal of Occupational Health and Safety

Noise is unwanted sound that comes from objects or equipment from the production process that can cause health problems in the form of hearing loss and non-hearing complaints. Non-auditory effects are symptoms caused by exposure to noise, but not on the hearing organ. This effects that affect health and well- being in a person such as physiological effects, psychological effects, and communication disturbance. The purpose of this study was to determine the effect of the level of noise exposure, worker characteristics, and worker behavior on non-auditory among workers in the unit 5-7 area of power generation company PT. X on …

Analisis Kasus Kecelakaan Pemboran Pada Industri Migas Di Pt.X Berdasarkan Faktor Manusia Tahun 2022, Siti Khodijah, Mufti Wirawan

National Journal of Occupational Health and Safety

Oil and gas drilling activities have associated high risks. 80% of the causes of drilling accidents are caused by human performance. In 2020, drilling activities at PT. X accounts for 3 out of 8 accidents and the common cause that occurs due to human factors. Unsafe acts are the main cause of drilling accidents in the oil and gas industry. This study discusses the analysis of cases of oil and gas drilling accidents at PT.X from the point of view of human factors. The purpose of this study is to analyze the contributing factors of active and latent failure and …

A Hypothetical New Challenging Use For Indocyanine Green Fluorescence During Laparoscopic Appendectomy: A Mini-Series Of Our Experience And Literary Review, Noemi Zorzetti, Augusto Lauro, Manuela Cuoghi, Marco La Gatta, Ignazio R. Marino, Salvatore Sorrenti, Vito D'Andrea, Andrea Mingoli, Giuseppe Giovanni Navarra

Department of Surgery Faculty Papers

Laparoscopic appendectomy (LA) is a well-standardized surgical procedure, but there are still controversies about the different devices to be used for the appendiceal stump closure and the related postoperative complications. Indocyanine green (ICG) fluorescence angiography (FA) has already been shown to be helpful in elective and emergency surgery, providing intraoperative information on tissue and organ perfusion, thus guiding the surgical decisions and the technical strategies. According to these two aspects, we report a mini-series of the first five patients affected by gangrenous and flegmonous acute appendicitis intraoperatively evaluated with ICG-FA during LA. The patients were admitted to the Emergency Department …

Analisis Faktor Risiko Kelelahan Kerja Pada Kurir Pt Tiki Jalur Ekakurir (Jne) Di Wilayah Kecamatan Pondok Gede Kota Bekasi Tahun 2022, Dinda Arsyah Febriana, Indri Hapsari Hapsari Susilowati

National Journal of Occupational Health and Safety

This study aims to describe the fatigue risk factors experienced by PT JNE couriers in the Pondok Gede District, Bekasi City in 2022. The study was conducted on 31 couriers operating in the Pondok Gede area and its surroundings in May – June 2022. This study uses a study cross-sectional with quantitative methods. The dependent variable of this study is work fatigue, and the independent variable is work-related risk factors (work shift, work duration, rest time), non-work risk factors (service period, commuting time, and satisfaction with the incentive and reward system), and individual factors (age, nutritional status, sleep quality, sleep …

The Effectiveness Of Microcurrent Neurofeedback On Depression, Anxiety, Post-Traumatic Stress Disorder, And Quality Of Life, Gloria Duke, Courtney N. Yotter, Beverly Sharifian, Gary Duke, Sandra Petersen

Nursing Faculty Publications and Presentations

Background: The world faces a mental health crisis with elevated rates of depression, anxiety, and post-traumatic stress, leaving a profound impact on daily quality of life (QOL). Current treatments show varying degrees of efficacy and carry burdensome challenges. Evidence exists for use of an innovative neurotechnology to reduce symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD), but the science is lacking for use in the general population. Purposes: The purpose of this pilot study was to explore the effects of microcurrent neurofeedback on depression, anxiety, PTSD symptoms, and QOL in adults. Methodology: This was a one-group, exploratory pilot study …

Phylogenetic Inference From Single-Cell Rna-Seq Data, Xuan Liu, Jason I Griffiths, Isaac Bishara, Jiayi Liu, Andrea H Bild, Jeffrey T Chang

Faculty, Staff and Student Publications

Tumors are comprised of subpopulations of cancer cells that harbor distinct genetic profiles and phenotypes that evolve over time and during treatment. By reconstructing the course of cancer evolution, we can understand the acquisition of the malignant properties that drive tumor progression. Unfortunately, recovering the evolutionary relationships of individual cancer cells linked to their phenotypes remains a difficult challenge. To address this need, we have developed PhylinSic, a method that reconstructs the phylogenetic relationships among cells linked to their gene expression profiles from single cell RNA-sequencing (scRNA-Seq) data. This method calls nucleotide bases using a probabilistic smoothing approach and then …

The Association Of Hobbies And Leisure Activities With Physician Burnout And Disengagement, Yan Li, Cindy Y. Lai, Bill Friedrich, Chenxing Liu, Joel H. Popkin

Journal of Wellness

Introduction: Burnout among physicians is a worldwide burden. While many causes of physician stress have been reported, we have found few quantitative studies of associations between burnout and participation in hobbies and interests outside of medicine. Our objective was to determine if health care professional burnout/disengagement could be mitigated by incorporating leisure interests and to characterize which specific interests, if any, are most significantly related.

Methods: We conducted an online survey of 2,563 US-based physicians and 512 residents/fellows and queried their participation in a list of 117 individual hobbies, which we then further categorized into three perceived levels …

Vertical Federated Learning Using Autoencoders With Applications In Electrocardiograms, Wesley William Chorney

Theses and Dissertations

Federated learning is a framework in machine learning that allows for training a model while maintaining data privacy. Moreover, it allows clients with their own data to collaborate in order to build a stronger, shared model. Federated learning is of particular interest to healthcare data, since it is of the utmost importance to respect patient privacy while still building useful diagnostic tools. However, healthcare data can be complicated — data format might differ across providers, leading to unexpected inputs and incompatibility between different providers. For example, electrocardiograms might differ in sampling rate or number of leads used, meaning that a …

The Effect Of An Aiming Device On The Accuracy Of Humeral Transcondylar Screw Placement, Katherine Neal

Theses and Dissertations

Canine cadaveric forelimbs (136) were randomly assigned to either treatment (aiming device) or control (fluoroscopic-guided) groups, and to either diplomate or resident for humeral transcondylar screw placement. Each limb underwent a transcondylar humeral screw placement from a lateral to medial direction. Digital radiography was used to evaluate screw trajectory, measured as deviation from the epicondylar line, and eccentricity on the humeral condyle. Procedure time, difference in outcome based on experience level, and complications were recorded. In the right limb, screw trajectory with the aiming device was decreased compared to fluoroscopy. There was no difference of accuracy between leg laterality with …

Evaluation Of The Virulence Potential Of Avian Pathogenic Escherichia Coli Isolated From Broiler Breeders With Colibacillosis In Mississippi, Jiddu Joseph

Theses and Dissertations

Avian pathogenic Escherichia coli (APEC) is a bacterium that is responsible for colibacillosis in birds. However, information about broiler breeder APEC isolates is limited, but the data is critical due to the transfer of this bacteria down the production pyramid to progenies resulting in high mortality. Therefore, we evaluated the phenotypic virulence characteristics of 28 isolates using embryo lethality and day-old chick challenge assays. Also, the in vitro adhesion and invasion potential of selected nine isolates were identified. Results showed more than 1/3^rd of the isolates were highly virulent and the virulence increased as the number of virulence-associated genes …

Loaded Lipid Emulsified Volatile Anesthetics In Canine Primary Hepatocytes, Patricia De Carvalho Ibrahim Obeid

Theses and Dissertations

In the 19th century, halothane hepatitis became a sensitive and well-known subject in human anesthesiology due to the production of a noxious metabolite further discovered, trifluoroacetic acid. Subsequently, isoflurane, enflurane, and desflurane were also investigated for potentially causing hepatitis through the same metabolite. Sevoflurane, however, does not generate trifluoroacetic acid and is quickly conjugated and excreted.

For more than four decades these anesthetics have been experimentally developed for intravenous injection by having added either a lipid or fluorocarbon-based carrier to produce general anesthesia with less drug and faster onset of action. The use of intravenous emulsified halogenated anesthetics as an …

Comparison Of Aging Techniques In Wild Bottlenose Dolphins (Tursiops Truncatus) Of Unknown Age From The Mississippi Sound., Christa Elizabeth Barrett

Theses and Dissertations

Age determination of bottlenose dolphins (Tursiops truncatus) is a critical tool in understanding their health. There are many methods of aging dolphins including morphometrics, counting growth layer groups (GLGs) of teeth, comparing dentin to pulp cavity ratio on dental radiographs, analysis of the pectoral flipper radiographs, and epigenetic testing. The most common method for aging toothed cetaceans is the counting of GLGs in the teeth. Since there are many challenges associated with aging dolphins based on the counting of GLGs, a processing technique that results in better resolution of GLGs is needed. This is a two-part study that …

A Survey Analysis Of Southeastern U.S. Dairy Producers’ Emotional States And Their Subjective Pain Perception Of Dairy Cows, Michelle M. Schuh

Theses and Dissertations

Dairy producers play a central role in evaluating and seeking treatment or care for animal pain. The primary aim of this study is to examine dairy producers’ emotional states and professional quality of life and analyze the relationship between these variables and their perception of pain in dairy cattle. Dairy farm owners and managers of 65 southeastern U.S. herds participated in a survey that included demographic information, the Depression, Anxiety, and Stress Scale, a modified Professional Quality of Life Scale, and 23 items requiring participants to evaluate various painful conditions in cattle.

Adherence To A Gluten-Free Diet And Depression, And Nutrient Distribution In Participants With Celiac Disease, Mohammad K. Shushari

Theses and Dissertations

Celiac disease (CD), an autoimmune disorder affecting millions of Americans, poses significant obstacles leading to a normal life. With no known cure, adherence to a strict glutenfree diet (GFD) is essential. However, the cost and limited availability of gluten-free alternatives can burden individuals with CD. Additionally, factors such as socioeconomic status, nutrient deficiencies, and the nature of the disease may contribute to mental health issues. This study aimed to investigate the influence of adherence to a GFD on depression in CD patients. The prevalence of depression among individuals with CD from diverse backgrounds was examined, along with the analysis of …

Metabolic Adaptation Of Staphylococcus Aureus Pathogenesis And Therapeutic Approach In Diabetic Foot Ulcers., Carol L. Baker

Theses and Dissertations

37.3 million Americans (11.2% of the US population) currently have Type 2 diabetes mellitus (T2DM) with over 1.5 million new cases being diagnosed each year. The multifactorial etiology of the patient having neuropathy, overweight/obesity, foot deformities, ischemia, and infection leads to a condition called diabetic foot ulcer (DFU). One in six patients with a DFU will require amputation with infected DFUs have a 155-fold increased risk of amputation. Staphylococcus aureus is the most common bacteria isolated from severe DFU infections that require amputation. Interestingly, diabetics are more heavily colonized with S. aureus compared to non-diabetics suggesting a unique advantageous adaptation …

Dog Tired: Examining The Relation Between Dog And/Or Cat Ownership And Owners’ Sleep, Courtney J. Bolstad

Theses and Dissertations

Sleep is an essential part of life, and obtaining quality sleep is important for various areas of functioning. Behaviors to promote sleep include physical activity, managing stress, reducing anxiety symptoms, maintaining a consistent sleep schedule, and obtaining bright light exposure. Many of these behaviors overlap with benefits observed from pet ownership (PO). The present study aimed to examine the relation between PO and sleep as well as moderators and mediators of this relation. Four research questions were examined: 1) Is PO significantly related to sleep? 2) Does gender moderate the relation between PO and sleep? 3) Do sleep-promoting behaviors (i.e., …