Medicine and Health Sciences Commons^™

Diabetes Mellitus: Interdisciplinary Medical, Surgical And Psychological Therapeutic Approach, Bogdan Socea, Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Cristian Balalau, Tiberiu Ștefăniță Tenea-Cojan, Doina Andrada Mihai, Ioana Paunica

Journal of Mind and Medical Sciences

Diabetes mellitus is a complex and widespread metabolic disease, having extremely complex implications (biological, psychological, social) for patients. Understanding the pathophysiology of diabetes (majorly influenced by various factors such as genetic predisposition, age, lifestyle choices, etc.) is essential for the prevention of this condition and the establishment of effective treatment strategies. The latest and relevant literature data related to the epidemiology, pathophysiology, and treatment of diabetes are presented, after an exhaustive review of the articles published on this topic and indexed in the WOS, PubMed, Scopus and Google Scholar databases. Preventing or delaying the onset of diabetes can be achieved …

From Covid-19 To Long Covid; The Forms Of The Neurological Manifestations, Sana Ahuja, Sufian Zaheer

Journal of Mind and Medical Sciences

Ever since the SARS-CoV-2 infection was declared a global pandemic in 2020, numerous multisystemic manifestations have been discovered. The COVID-19 is known to cause a wide spectrum of neurological symptoms like fatigue, headache, brain fog, stroke, smell and taste disorders, encephalopathy and neurodegenerative disorders. The neurological manifestations are more prevalent in the post-COVID syndrome or long COVID. The National Institute for Health and Care Excellence and WHO defined Ongoing Symptomatic COVID as 4-12 weeks post infection and post COVID-19 syndrome as persistence of symptoms beyond 12 weeks. So far there are limited data available regarding the pathophysiology of neurological symptoms …

Gastric Cancer; Actualities And Perspectives Of Early Diagnosis And Targeted Therapy, Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Anca Dumitriu, Stana Paunica, Cristian Balalau, Stefăniță Tenea Cojan, Dragos Epistatu, Vlad Denis Constantin

Journal of Mind and Medical Sciences

Gastric cancer is an extremely aggressive form of malignancy that, if left untreated, is life-threatening. Improved survival rates depend on early detection of the disease, as well as on the combination of different forms of treatment (surgery, chemotherapy, radiotherapy, immunotherapy, etc.). Screening methods have brought real benefit in early detection of malignancies, but many cases are still diagnosed at advanced stages. The current study is a review related to actualities and perspectives of early diagnosis and targeted therapy of gastric cancer. After an extensive review of the literature, epidemiological, diagnostic and treatment data are presented. The open surgical approach is …

Evaluating The Effectiveness Of Chess As A Therapeutic Tool In The Comprehensive Management Of Adhd, Neilay Krishna Agarwal

Journal of Mind and Medical Sciences

Using databases such as PubMed and Google Scholar with the keywords "Chess" and "ADHD", this study was conducted to review the literature on the usefulness of chess in patients with ADHD. The most relevant articles were searched using the following criteria: English language, and all types of studies published in a medical journal. A total 12 articles were identified. Of a total of 12 articles, 4 met the inclusion criteria and were subsequently reviewed. The results of the review showed that chess therapy/training is effective in the management of ADHD patients in terms of reducing symptoms and severity. Due to …

Barrett's Esophagus As A Premalignant Condition; Medical And Surgical Therapeutic Management, Vlad Denis Constantin, Adrian Silaghi, Laura Florentina Rebegea, Stana Paunica, Anca Silvia Dumitriu, Doina Andrada Mihai, Ioana Paunica, Dragos Epistatu

Journal of Mind and Medical Sciences

Barrett's esophagus (BE) represents a special clinical entity, which may have reduced symptoms, but an increased potential for malignant degeneration. The factors that lead to the appearance of Barrett's esophagus are multiple, the most important being gastro-esophageal reflux, as well as smoking and obesity. BE occurs as a result of damage of the esophageal mucosa, caused by acid/basic gastroesophageal reflux and resulting in the transformation of the epithelium from squamous to intestinal type. The diagnosis of BE is primarily based on endoscopic examination. This method has not only a diagnostic role, but also a therapeutic one through the minimally invasive …

Psychological Violence And Manipulative Behavior In Couple: A Focus On Personality Traits, Carmela Mento, Clara Lombardo, Nicholas Whithorn, Maria Rosaria Anna Muscatello, Antonio Bruno, Maura Casablanca, Maria Catena Silvestri

Journal of Mind and Medical Sciences

Psychological violence is characterized by systematic denigration and humiliation of the partner (victim). It is an insidious and manipulative behavior put in place to ensure that the victim begins to doubt themselves, and their own judgments, to the point of feeling confused and wrong. This behavior pattern is called Gaslighting and the personality traits are characterized by lack of empathy, psychopathy, narcissism and Machiavellianism. These three conditions are part of the so-called dark triad and distinguished by the lack of empathy. The aim of this study is to explore psychological aspects and consequences of Gaslighting phenomena. This systematic review was …

Addressing Racism In Medicine With Community-Based Doula Services For Black Mothers, A Narrative Review Of The Literature And Historical Perspective, Brianna Roberts Canales, Emily Sloane

Marshall Journal of Medicine

No abstract provided.

Perceptions Of Diabetes Distress And Counseling During The Pandemic - Rural Provider Perspectives, Ranjita Misra, Brenna O. Kirk, William D. Lewis

Marshall Journal of Medicine

Introduction

West Virginia is an Appalachian rural state that ranks highest in the nation in the prevalence of diabetes (16.2%). The COVID-19 pandemic impacted routine diabetes care. As a result, individuals experienced diabetes distress over the physical and psychological burdens of diabetes management. In rural and medically underserved counties (71%), diabetes care is often provided by primary care physicians. However, healthcare providers’ perspectives on diabetes distress and related counseling to address them are unclear. This cross-sectional study’s objective was to explore healthcare providers’ (HCP) perspectives regarding their patient’s diabetes distress and how it guided their counseling for diabetes self-care during …

Enhancing The Rates Of Advance Directive Documentation To Improve The Quality Of Patient Care, Sydney Sheppard, Katie Salyers, Carolyn Curtis, Adam Franks Franks, Courtney Wellman

Marshall Journal of Medicine

Introduction

Advance Directives (AD) allow patients to maintain autonomy during incapacitation. Patients and their caregivers benefit from these documents in times of crisis. Overcoming barriers to AD completion and documentation can improve patient care quality.

Methods

A retrospective chart review was performed initially, after consolidation of the electronic health record (EHR) and after alteration of the EHR, to evaluate the availability of a patient’s medical power of attorney (MPOA), living will (LW), and code status.

Results

Baseline documentation of MPOA (7.33%), LW (6.00%), and code status (5.33%) within the outpatient EHR was low. After 2 cycles, this improved to 13.10%, …

Successful Surgical Outcome After Traumatic Diaphragmatic Intra-Pericardial Herniation From Blunt Abdominal Injury, Tyler Bayliss, Mark H. Cooper, Paul Bown

Marshall Journal of Medicine

Intrapericardial diaphragmatic hernia (IPDH) is a rare manifestation of non-hiatal diaphragmatic hernias (NHDH). Intrapericardial diaphragmatic hernia is defined as the prolapse of the abdominal viscera into the pericardium through the diaphragm. Their incidence has increased over the last 50-60 years, secondary to high-speed transport, and constitutes 5% of major thoracic and abdominal trauma today. These injuries can present during the initial workup or months after the initiating injury. These hernias can be caused by both blunt and penetrating trauma with concomitant central tendon rupture and pericardial laceration. We report an interesting case of intrapericardial diaphragmatic hernia with delayed presentation that …

Chronic Exertional Compartment Syndrome: A Case Report About Claudication In A Healthy Adult, Adrienne Mays-Kingston, Jeremy Eckels, Holly Farkosh, Austin Nichols, Paris Johnson, Adam M. Franks

Marshall Journal of Medicine

Claudication occurs when the blood supply is insufficient to service the musculature in the body with oxygen and metabolic waste management. A clinical complaint of claudication is commonly seen in primary care among older patients with vascular risk factors. A young and healthy patient presenting with claudication is less common and often results in delayed diagnosis with numerous extraneous diagnostic studies. This case discusses a young, healthy male patient with lower extremity symptoms that got worse with exercise and better with rest. He had normal physical exam findings leading to multiple diagnostic studies and over 12 months between the onset …

The Future Of Medicine Is Behind Us: The Case For A 1912 Case-Based Curricula, Aaron Mcguffin

Marshall Journal of Medicine

Patient outcomes continue to suffer despite exponential advances in access to medical knowledge. This requires an evaluation of the pedagogy of our medical education delivery. Case-based learning has long been shown to be an effective teaching method to improve student knowledge, student and faculty engagement, and improve patient outcomes. In order to improve patient outcomes specifically in accurate and timely diagnosis, we need to strongly consider converting our existing curricular models entirely to a case-based format.

Synaptic Proteins Involved In Reward-Based Plasticity, Cameron Martinez, Christian Wesselborg, Hey-Kyoung Lee Ph.D

Trick to the Treat of Internships and Research

My research focused on synaptic proteins involved in reward-based plasticity. More specifically, my aim sought to expand brain tissue in order to resolve the problem of distinguishing between synapses. This process involved using different biological assays.

Clear Vision Center Of South Florida Biol 4990 - Independent Study In Biology, Bita Sabripour

Trick to the Treat of Internships and Research

During my internship at Clear Vision Center of South Florida, I had the opportunity to shadow and work alongside Dr. Bita Sabripour to examine and provide eye care services to patients. I learned various clinical practices including taking patients' history, working the front desk, taking inventory, placing orders, selling frames, assisting patients, and keeping the office running. In addition, I ran the clinic's social media platforms and was in charge of communication with various manufacturers and sales representatives. I also volunteered with the associated nonprofit organization, See Your Future, which provides free eye care and services to the underprivileged and …

Dietary Interventions During Chemotherapy Treatment: A Systematic Review Of Feasibility, Safety, And Efficacy, Shalet James, Alexie Oppermann, Amber S. Kleckner

Trick to the Treat of Internships and Research

Chemotherapy is a mainstay for cancer treatment. However, chemotherapy is associated with side effects that can significantly limit a person's physical and cognitive functioning, both reducing quality of life and leading to dose reductions of life-saving treatment. Dietary interventions may help manage and reduce the side effects of chemotherapy through biological and psychological mechanisms. While there is preliminary evidence supporting the importance of nutrition in cancer care, current guidelines are vague except for minimum calorie and protein intake to prevent malnutrition. The aim of this systematic review is to evaluate the feasibility, safety, and efficacy of dietary interventions on health …

Minimum Blockers Of 123-Avoiding Permutation Matrices, Megan Bennett

Trick to the Treat of Internships and Research

A blocker of 123-avoiding permutation matrices refers to the set of zeros contained within an 𝑛 × 𝑛 123-forcing matrix. Recently, Brualdi and Cao provided a characterization of all minimal blockers, which are blockers with a cardinality of 𝑛. Building upon their work, a new type of blocker, flag-shaped blockers, which can be seen as a generalization of the 𝐿-shaped blockers defined by Brualdi and Cao, are introduced. It is demonstrated that all flag-shaped blockers are minimum blockers, and the shifting of positions from these blockers is discussed. Lastly, the dimensions of subpolytopes that are defined by flag-shaped blockers are …

Introduction To Protein Modeling, Jordan Nichole Carreras, Juhi Dalal, Ryan Luib, Omar Saleh, Pranav Neravetla, Shreya Averinini

Trick to the Treat of Internships and Research

HONR 1010G: Introduction to Protein Modeling is a course-based research opportunity focused on telling a “protein story” using a 3dprinted model developed by students working in research groups studying the literature and available protein database files. The course is open to honors students at all levels and majors. Throughout the semester, students work to develop a 3D printed model that explains how the protein works. This is done through using computational tools with protein database file published through the protein data bank (https://www.rcsb.org/) such as Jmol & Pymol, scientific literature and 3D protein models. In addition to creating the 3dprinted …

Investigating The Gut Microbiota Of Skeleton Shrimp, Jason Rosales

Trick to the Treat of Internships and Research

No abstract provided.

How Did The Covid-19 Pandemic Impact Anatomy And Physiology Education Worldwide, Sneh Patel, Sean Mahajan, Santanu De

Trick to the Treat of Internships and Research

No abstract provided.

Sea-Phages Research, Bianca Gonzalez

Trick to the Treat of Internships and Research

Bacteriophages are viruses that infect and kill bacteria and there is an abundant amount of them in the world. They have been recently utilized in biotechnological applications including their use in combating antibiotic resistance and bioremediation of oil spills. Through the SEA-PHAGES program, my goal (along with my team) was to discover and isolate bacteriophages found in soil and analyze their full genome sequences

Md Anderson Internship: Targeting Il-27rα In Ovarian Cancer, Meghana Kavarthapu

Trick to the Treat of Internships and Research

We utilized a novel explainable artificial intelligence (XAI) approach to identify Interleukin-27 Receptor α (IL-27Rα) as a potential therapeutic target for high grade serous ovarian cancer (HGSC) patients based on the Cancer Genome Atlas (TCGA) dataset. High expression of IL-27Rα was found to be significantly correlated with poorer survival in HGSC patients. To investigate its therapeutic potential, we silenced IL-27Rα in murine HGSC cells lines using siRNA and assessed its impact on tumor proliferation, migration, invasion, and angiogenesis. Our results demonstrated that IL-27Rα siRNA effectively reduced its expression, as confirmed by Western Blot analysis, and significantly attenuated proliferation by clonogenic …

Florida's Summer Institute In Biostatistics And Data Science Program Experience, David Giordano

Trick to the Treat of Internships and Research

The Summer Institute in Biostatistics and Data Science, sponsored by the NHLBI and NIAID, offers a comprehensive six to seven-week training program. This program provides classroom instruction, career mentoring, and hands-on data analysis using clinical study data related to infectious, immune-mediated, and chronic diseases. It's designed to address the increasing demand for biostatisticians and data scientists, targeting undergraduates and early graduate students to consider graduate programs in these fields. The curriculum includes intensive biostatistical training, introducing students to statistical methods' principles and applications in biomedical and clinical research.

Pre-Health Professional Volunteer, Divya Papaiya

Trick to the Treat of Internships and Research

I participated in the esteemed Pre-Health Professional Volunteer Program at Penn Medicine Princeton Health over this summer from May to August. Through this program, I was able to rotate through various departments in the hospital ranging from – but not limited to – Radiation Oncology to the Pathology/Blood Bank Lab. Along with completing my rotations, I was a part of a close-knit cohort that was able to attend special lectures dedicated to a variety of healthcare topics such as medical treatment inequality and disparity, EMS services, organ donation, and medical examiner (autopsy) recognition cases. Despite being part of a specialized …

Big 5 Conservation Internship, Bernhard Riegl

Trick to the Treat of Internships and Research

The Discover Eden Big 5 Ecology and Conservation course is located in South Africa. Through a series of first-hand experiences and lectures, one learns much about Conservation and what it really is. By working with Ecologists, Conservationists, and Veterinarians, you gain insight into these professions and what they entail

Summer 2023 Graz Internship, Eleanor Wind, Alex Pope

Trick to the Treat of Internships and Research

The summer 2023 Graz Internship was a comprehensive medical internship which exposed us to both surgical and clinical sides of medicine. Over the course of 6 weeks we were able to observe a variety of operations and even scrub in and assist. Clinical skills acquired included IV placement, phlebotomy, laparoscopy, suturing and surgical knot tying. In addition to experience gained in the hospital, we learned the basics of international travel, citywide navigation in multiple cities, European culture, and ate quite a bit of good food. We were fortunate enough to meet a network of medical students and doctors from other …

Science Alive, Adam Sadik, Pranav Madadi, Mahalaxmi Some, Lohita Sunkara, Ashley Abad, Lickchina Jeanlis

Trick to the Treat of Internships and Research

Through the Science Alive outreach program, we work to bring the excitement of hands-on learning to grade-school children and the entire community. Science Alive promotes science education and interaction between the college and grade school community as “science buddies”. Group leaders can earn Science Alive internship credit and serve as volunteers with Broward County public schools. There are a variety of ways NSU students are involved in this internship program. We have a regular schedule of leading students once per week on Friday afternoons at Nova Blanche Elementary through NSU student-led activities to explore science. We also have been building …

Uptitrating Mycophenolate Mofetil Therapy In A Patient With Lupus Cerebritis Doesn’T Increase Risk Of Infection Compared To Cyclophosphamide, Gautham Pavar

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising

Appel GB, Contreras G, Dooley MA, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J Am Soc Nephrol. 2009;20(5):1103-1112. https://doi.org/10.1681/ASN.2008101028

for a patient with neuropsychiatric lupus.

Cârța Monastery, Barbara L. Gracious

HCA Healthcare Journal of Medicine

The Cârța Monastery, a former Cistercian monastery, is pictured here from one of its sides, conjuring the romanticism that is beloved in medieval ruins. The photo was taken on a sunny fall afternoon in the Țara Făgărașului region of Romania in southern Transylvania. Cârța Monastery was started around 1202 by a group of Cistercian monks from Egres Abbey in the then-kingdom of Hungary. Cistercian architecture is considered some of the most beautiful of the Middle Ages, and walking the grounds of the Monastery indeed evoked a profound sense of gratitude, awe, and peace in the shadow of its beauty that …

Implications Of Covid-19 On A Rapidly Growing Thymoma Case, Neeraja Narayanan, Shoaleh Motamedi, Christian Lalonde, Mikko Tauriainen

HCA Healthcare Journal of Medicine

Introduction

Thymomas are a rare form of slow-growing malignancy that originate from thymic epithelial cells presenting as an anterior mediastinal mass. Although most are asymptomatic, they can have a variety of presentations, such as local thoracic symptoms, superior vena cava syndrome, or paraneoplastic syndromes. Local compressive thoracic symptoms include shortness of breath, chest pain, and cough. Superior vena cava syndrome presents with respiratory, vascular, or neurologic symptoms. Paraneoplastic syndromes, such as myasthenia gravis, are due to abnormal T-cell maturation leading to an increased risk of autoimmune conditions.

Case Presentation

We report a case of a 71-year-old White male with multiple …

Ciprofloxacin-Induced Peripheral Neuropathy: A Case Report, Alexander Refaeian, Eric L. Vest, Michael Schmidt, Jorge D. Guerra, Mohd N. Refaei, Michael Refaeian, Ryan A. Floresca, Manouchehr Refaeian

HCA Healthcare Journal of Medicine

Introduction

Fluoroquinolones, a class of antibiotics, are commonly employed in the treatment of a wide array of bacterial infections. Recognized for their effectiveness against a broad spectrum of pathogens, fluoroquinolones have played a pivotal role in managing conditions like urinary tract infections and respiratory diseases. Nevertheless, their usage is not without contention due to their association with a variety of adverse effects, including tendon rupture and the less frequently reported issue of peripheral neuropathy.

Case Presentation

We present the case of a 42-year-old male who developed peripheral neuropathy several days after completing a 10-day course of ciprofloxacin for gastroenteritis. The …