Medicine and Health Sciences Commons^™

A Phenomenological Exploration Of Women’S Lived Experiences During Their Pregnancy Lifecycle, Ashley J. Blount, Charmayne R. Adams, Kara M. Schneider, Gurudutt Pendyala, Ann L. Anderson-Berry, Corrine Hanson

Office of Health Promotion Scholarship

When considering peri-and-post natal health, there are several biopsychosocial risk factors at play. Biological, psychological, and social health factors are significant in contributing to maternal wellbeing and influencing maternal morbidity/mortality [1]. The Covid-19 pandemic had significant impacts on general populations and on vulnerable groups such as pre-peri-and-post natal women [2]. In previous epidemics, pregnant women were reluctant to attend hospitals and doctors’ appointments due to fear of infection [3]. Covid-19 has shown similar effects [2] and as such, risks associated with the pregnancy lifecycle have increased. A phenomenological investigation found themes of women experiencing negative healthcare, struggles with self-advocacy, heightened …

Clinical Practice Patterns Of Speech-Language Pathologists For Screening And Identifying Dysphagia, Matthew Dumican, Zoë Thijs Ph.D., Kaitlynn Harper

Communication Sciences and Disorders: Faculty Publications

Purpose: To identify how speech-language pathologists (SLPs) in the UnitedStates are screening for and identifying dysphagia. To do this, we examined theapproaches most often used to screen for dysphagia and the influence of contex-tual factors such as setting, continuing education and means of staying up to datewith the most current literature on screening approaches.Method: A web-based survey composed of 32 questions was developed andfield tested for content, relevance and workflow. The survey was distributedonline, via social media, online SLP forums and through the American Speech-Language-Hearing Association’s Special Interest Group 13 (swallowing disor-ders). One hundred and thirty-seven clinicians from the United …

Association Of Elevated Serum Aldosterone Concentrations In Pregnancy With Hypertension, Robin C. Shoemaker, Marko Poglitsch, Dolph Lewis Davis Iii, Hong Huang, Aric Schadler, Neil Patel, Katherine Vignes, Aarthi Srinivasan, Cynthia Cockerham-Morris, John Anthony Bauer, John M. O’Brien

UK CARES Faculty Publications

Emerging evidence indicates a previously unrecognized, clinically relevant spectrum of abnormal aldosterone secretion associated with hypertension severity. It is not known whether excess aldosterone secretion contributes to hypertension during pregnancy. We quantified aldosterone concentrations and angiotensin peptides in serum (using liquid chromatography with tandem mass spectrometry) in a cohort of 128 pregnant women recruited from a high-risk obstetrics clinic and followed prospectively for the development of gestational hypertension, pre-eclampsia, superimposed pre-eclampsia, chronic hypertension, or remaining normotensive. The cohort was grouped by quartile of aldosterone concentration in serum measured in the first trimester, and blood pressure, angiotensin peptides, and hypertension outcomes …

Impact Of Common Face Mask Regeneration Processes On The Structure, Morphology And Aerosol Filtration Efficiency Of Porous Flat Sheet Polysulfone Membranes Fabricated Via Nonsolvent-Induced Phase Separation (Nips), Ebuka A. Ogbuoji, Anastasia Myers, Amber Haycraft, Isabel Escobar

UK CARES Faculty Publications

The potential of flat sheet polymeric membranes as a sustainable solution for reusable facemask filters was investigated by analyzing the effect of common face mask regeneration processes on polysulfone (PSf) membranes’ structure, morphology, and aerosol filtration efficiency. The impact of regeneration processes, such as isopropanol (IPA), detergent and bleach washes, and ultraviolet light exposure, was for the first time compared between surgical masks, N95 masks and flat sheet PSf membranes. The PSf membranes were fabricated via non- solvent induced phase separation (NIPS), and demonstrated a higher particulate filtration efficiency (99.06 ± 1.38%) for PM0.3 i.e., particulate matter of 0.3 μm …

Nursing News & Views - November 2023, Joanne Miller Rn

Nursing Newsletters

No abstract provided.

Occupational Therapy Feeding Interventions In The Neonatal Intensive Care Unit: A Systematic Review, Karly Boehm, Lindsey Brechbill, Johana Cedillo, Sara Mengler, Allyson Thomas

Student Systematized Reviews: Occupational Therapy

No abstract provided.

A Word From The Writing Team (November 2023), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• New!! Check Out Our OPWPC Resources Page in Canvas
• First Friday Writing Retreats Continue - This Friday
• The Annual Yeo Writing Prize is Back
• Learn How AI Impacts Scholarly Writing, Reviewing, and Publishing
• Publication Spotlight
• Reminders
• Consultations Available
• Scott Memorial Library Renovations
• Wiley Open Access Fees Waived for Jefferson Authors

2023 - The Fourth Annual Fall Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Fall 2023 Symposium of Student Scholars, held in November 2023. Includes abstracts from the presentations and posters.

Prediction Of Central Visual Field Measures From Macular Oct Volume Scans With Deep Learning, Vahid Mohammadzadeh, Arvind Vepa, Chuanlong Li, Sean Wu, Leila Chew, Golnoush Mahmoudinezhad, Evan Maltz, Serhat Sahin, Apoorva Mylavarapu, Kiumars Edalati, Jack Martinyan, Dariush Yalzadeh, Fabien Scalzo, Joseph Caprioli, Kouros Nouri-Mahdavi

All Faculty Open Access Publications

Purpose: Predict central 10° global and local visual field (VF) measurements from macular optical coherence tomography (OCT) volume scans with deep learning (DL). Methods: This study included 1121 OCT volume scans and 10-2 VFs from 289 eyes (257 patients). Macular scans were used to estimate 10-2 VF mean deviation (MD), threshold sensitivities (TS), and total deviation (TD) values at 68 locations. A three-dimensional (3D) convolutional neural network based on the 3D DenseNet121 architecture was used for prediction. We compared DL predictions to those from baseline linear models. We carried out 10-fold stratified cross-validation to optimize generalizability. The performance of the …

Chain Conformation And Exciton Delocalization In A Push-Pull Conjugated Polymer, Yulong Zheng, Rahul Venkatesh, Connor P. Callaway, Campbell Viersen, Kehinde H. Fagbohungbe, Aaron L. Liu, Chad Risko, Elsa Reichmanis, Carlos Silva-AcuñA

UK CARES Faculty Publications

Linear and nonlinear optical line shapes reveal details of excitonic structure in polymer semiconductors. We implement absorption, photoluminescence, and transient absorption spectroscopies in DPP-DTT, an electron push−pull copolymer, to explore the relationship between their spectral line shapes and chain conformation, deduced from resonance Raman spectroscopy and from ab initio calculations. The viscosity of precursor polymer solutions before film casting displays a transition that suggests gel formation above a critical concentration. Upon crossing this viscosity deflection concentration, the line shape analysis of the absorption spectra within a photophysical aggregate model reveals a gradual increase in interchain excitonic coupling. We also observe …

Conversion Of Catechol To 4-Nitrocatechol In Aqueous Microdroplets Exposed To O3 And No2, Md Sohel Rana, Seth T. Bradley, Marcelo I. Guzman

UK CARES Faculty Publications

Catechol is a widespread atmospheric dihydroxybenzene present in vehicle emissions, biomass burning, and combustion pollution plumes. Although the daytime reactivity of catechol is controlled by ozone (O3) and hydroxyl radicals (HO), the action of nitrate radicals (NO3) on the surface of aqueous atmospheric particles should become significant at night. This work simulates nighttime interfacial chemistry between hydrated catechol and adsorbed NO3 to form 4-nitrocatechol during experiments lasting ≤1 μs. Surface-sensitive online electrospray ionization mass spectrometry (OESI-MS) examines the reaction on the water surface under variable ratios of [NO2] and [O3]. The produced 4-nitrocatechol is quantified by a standard addition in …

Development Of Poly(Acrylamide)-Based Hydrogel Composites With Powdered Activated Carbon For Controlled Sorption Of Pfoa And Pfos In Aqueous Systems, Maria Victoria X. Klaus, Angela M. Gutierrez, J. Zach Hilt

UK CARES Faculty Publications

Per- and polyfluoroalkyl substances (PFAS) are anthropogenic compounds developed for various applications; some are connected to adverse health impacts including immunosuppression and higher susceptibility to some cancers. Current PFAS remediation treatments from aqueous sources include granular activated carbon (GAC) adsorption, membrane separation, and anion- exchange resin (AER) removal. Each has specific disadvantages, hence the need for a new and efficient technology. Herein, acrylamide-based hydrogel composites were synthesized with powdered activated carbon (PAC) and characterized to determine their affinity for PFAS. Physicochemical characterization included Fourier-Transform infrared spectroscopy (FTIR) to identify chemical composition, thermogravimetric analysis (TGA) to confirm PAC loading percentage, and …

Benchmark Dataset For Training Machine Learning Models To Predict The Pathway Involvement Of Metabolites, Erik D. Huckvale, Christian D. Powell, Huan Jin, Hunter N. B. Moseley

Markey Cancer Center Faculty Publications

Metabolic pathways are a human-defined grouping of life sustaining biochemical reactions, metabolites being both the reactants and products of these reactions. But many public datasets include identified metabolites whose pathway involvement is unknown, hindering metabolic interpretation. To address these shortcomings, various machine learning models, including those trained on data from the Kyoto Encyclopedia of Genes and Genomes (KEGG), have been developed to predict the pathway involvement of metabolites based on their chemical descriptions; however, these prior models are based on old metabolite KEGG-based datasets, including one benchmark dataset that is invalid due to the presence of over 1500 duplicate entries. …

Ada Deficiency: Improvement In Immune Function After Enzyme Replacement Therapy, Esosa Adah, Nikita Raje

Posters

Introduction: Adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID) is characterized by severe lymphocytopenia affecting T-, and B-,lymphocytes, with non-immunological manifestations including neurodevelopmental deficits, sensorineural deafness, and skeletal abnormalities. Treatment modalities include enzyme replacement therapy(ERT) and/or autologous gene therapy or hematopoietic stem cell treatment. We report a 9-month-old female with ADA deficient T-B-NK+ SCID treated with ERT while awaiting stem cell treatment. Case Description: A 9-month-old female with a history of failure to thrive, hypotonia and loss of developmental milestones had genetic testing done that showed variants ADA c.911 T>G, c.302G>A. She was admitted for further work up. Lymphocyte …

Psychological Safety And Conflict Management Among Nurse Practitioners In Interprofessional Teams, Scott Tyler Faust

Electronic Theses and Dissertations

This quantitative correlational study explored the relationships between perceived psychological safety, conflict management styles, and perceived conflict management success among nurse practitioners (NPs) operating in interprofessional acute or critical care teams in the United States. Despite existing literature on conflict management and psychological safety, there is a noticeable gap concerning the interplay of these factors, specifically among NPs. A multi-item survey was developed from validated measures to assess psychological safety, conflict management success, and conflict management style. The final sample included 944 NPs. The findings revealed a statistically significant difference in the scores of perceived psychological safety, depending on the …

Reduced Risk Of Dementia In Patients With Type 2 Diabetes Mellitus Using Chinese Herbal Medicine: A Nested Case-Control Study, Hou-Hsun Liao, Hanoch Livneh, Hua-Lung Huang, Jui-Yu Hung, Ming-Chi Lu, How-Ran Guo, Tzung-Yi Tsai

Counselor Education Faculty Publications and Presentations

Dementia is a prevalent condition in type 2 diabetes mellitus (T2DM) patients. While Chinese herbal medicine (CHM) is often employed as complementary therapy for glycemic control, its effect in controlling likelihood of dementia has not yet been fully elucidated. AIM To compare the risk of dementia between T2DM patients with and without CHM treatment. METHODS We undertook a nested case-control study and obtained data on patients 20-70 years of age who received medical care for T2DM between 2001 and 2010 from the National Health Insurance Research database in Taiwan. Cases, defined as those with dementia that occurred at least one …

Tunnel-Free Acromioclavicular Joint Reconstruction Is Associated With Improved Initial Reduction And Higher Patient Satisfaction, Brittany A Olsen, Joshua W Rollins, Daniel H Ngo, James M Gregory

Faculty, Staff and Student Publications

BACKGROUND: Many surgical techniques have been described for acromioclavicular (AC) joint reconstruction. Creation of bone tunnels through the clavicle or coracoid has been shown to be a risk factor for fracture. Use of an AC reconstruction technique that does not create bone tunnels may obviate this risk. This study aims to evaluate clinical outcomes of AC joint reconstruction using a tunnel-free technique compared to reconstruction using a cortical button and clavicular drill holes.

METHODS: Consecutive patients who underwent AC joint reconstruction by a single surgeon in a subspecialty referral practice were included. One group of patients received cortical button fixation …

Healthaichain: Improving Security And Safety Using Blockchain Technology Applications In Ai-Based Healthcare Systems, Naresh Kshetri, James Hutson, Revathy G

Faculty Scholarship

Blockchain as a digital ledger for keeping records of digital transactions and other information, it is secure and decentralized technology. The globally growing number of digital population every day possesses a significant threat to online data including the medical and patients’ data. After bitcoin, blockchain technology has emerged into a general-purpose technology with applications in medical industries and healthcare. Blockchain can promote highly configurable openness while retaining the highest security standards for critical data of medical patients. Referred to as distributed record keeping for healthcare systems which makes digital assets unalterable and transparent via a cryptographic hash and decentralized network. …

Biological And Environmental Factors May Affect Children’S Executive Function Through Motor And Sensorimotor Development: Preterm Birth And Cerebral Palsy, Iryna Babik, Andrea B. Cunha, Sudha Srinivasan

Psychological Sciences Faculty Publications and Presentations

Disruptive biological and environmental factors may undermine the development of children’s motor and sensorimotor skills. Since the development of cognitive skills, including executive function, is grounded in early motor and sensorimotor experiences, early delays or impairments in motor and sensorimotor processing often trigger dynamic developmental cascades that lead to suboptimal executive function outcomes. The purpose of this perspective paper is to link early differences in motor/sensorimotor processing to the development of executive function in children born preterm or with cerebral palsy. Uncovering such links in clinical populations would improve our understanding of developmental pathways and key motor and sensorimotor skills …

The Persistence Of Blue Ash In The Aftermath Of Emerald Ash Borer May Be Due To Adult Oviposition Preferences And Reduced Larval Performance, Don Cipollini, Emily Morton

Biological Sciences Faculty Publications

1. We examined the health of mature blue ash, Fraxinus quadrangulata, in two forests in southwestern Ohio in relation to that of mature white ash, F. americana, and examined the potential importance of oviposition preferences and larval resistance in the persistence of blue ash.
2. Both blue ash and white ash were largely unaffected by emerald ash borer in 2012. By 2018, nearly 90% of the blue ash trees observed in these forests had full or nearly full canopies, as opposed to less than 20% of the white ash encountered in our studies. In 2021, blue ash maintained a …

Diabetes-Associated Hyperglycemia Causes Rapid-Onset Ocular Surface Damage, Judy Weng, Christopher Ross, Jacob Baker, Saleh Alfuraih, Kiumars Shamloo, Ajay Sharma

Pharmacy Faculty Articles and Research

Purpose: The metabolic alterations due to chronic hyperglycemia are well-known to cause diabetes-associated complications. Short-term hyperglycemia has also been shown to cause many acute changes, including hemodynamic alterations and osmotic, oxidative, and inflammatory stress. The present study was designed to investigate whether diabetes-associated hyperglycemia can cause rapid-onset detrimental effects on the tear film, goblet cells, and glycocalyx and can lead to activation of an inflammatory cascade or cellular stress response in the cornea.

Methods: Mouse models of type 1 and type 2 diabetes were used. Tear film volume, goblet cell number, and corneal glycocalyx area were measured on …

Bowel Cleanout Prior To Intrathecal Baclofen Pump Implantation: Effects On Acute Post- Operative Gastrointestinal Complications, Amanda Lindenberg, Brittni Walton, Sathya Vadivelu, Matthew J. Mclaughlin

Posters

Background: Intrathecal baclofen (ITB) pumps have been used for management of spasticity and dystonia There is limited data on immediate post-operative complications such as GI adverse events after surgery for ITB pump related procedures. This study aimed to compare patients who underwent a pre-operative bowel cleanout to those who did not and the relationship with post-operative nausea, vomiting and constipation requiring an escalation of their bowel regimen. Design: Retrospective cohort study. Setting: Pediatric acute care hospital. Participants: All patients who underwent new ITB pump and/or catheter placement from January 2015-December 2022. Interventions: Preoperative bowel clean out. Main Outcome Measure: Quantity …

Privacy Preserving Self-Service Degauss Based Geomarker Portal, Harpreet Gill, Kushal Vallambhatla, Mark A. Hoffman, Kevin Power, Catherine Jackson

Posters

DeGAUSS offers a privacy-preserving capability to annotate a list of addresses with geomarker information that is useful for social determinants and other research. The standard delivery of DeGAUSS requires command line proficiency, potentially limiting the group of users. We provide a self-service portal that enables researchers to load a file and receive a downloadable annotated output file. In our pilot phase, the system has processed 481 calls for more than 45,000 addresses at Children’s Mercy.

Increasing Annual Eye Exam Completion For Children With Cystic Fibrosis Receiving Cftr Modulators, Paula Capel, Claire Elson, Stephanie Duehlmeyer, Jessica Haynes, Amanda Conway, Christopher M. Oermann

Posters

Background: CFTR modulators are life-changing therapy for people with CF. During preclinical studies of ivacaftor, cataracts were identified in juvenile rat pups. Subsequently, noncongenital cataracts have been reported in children receiving CFTR modulator therapy [1], so baseline and annual slit lamp eye examinations for cataract development are recommended for children with CF (aged <18). At Children’s Mercy Kansas City (CMKC), our standard practice is to conduct baseline and annual ophthalmologic examinations to assess for cataracts in children with CF prescribed CFTR modulator therapy, but there was no formal process for tracking adherence to this standard and ensuring that examinations were completed. A quality improvement project was undertaken in May 2022 to determine the rate of completion of annual eye exams and increase adherence to our annual monitoring standard.

Methods: To improve adherence to annual monitoring standards, a quality improvement taskforce including CF care team nurses and pharmacists was developed. A database was used to document baseline and follow-up eye examinations. A standardized communication process was developed and deployed that included an eye exam brochure (Figure …

Examining The Evidence Base For Burnout, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

Burnout has elicited growing interest among occupational health specialists in recent decades. Since 2019, the World Health Organization has characterized burnout as a syndrome resulting from chronic, unmanageable workplace stress. According to the ICD-11, three symptoms define the entity: feelings of exhaustion, increased mental distance from one’s job, and a sense of ineffectiveness at work, all of which correspond to the structure of the Maslach Burnout Inventory. The ICD-11 includes burnout among the factors that influence health status. This paper calls into question that conceptualization based on a number of lines of evidence. The evidence includes the following: burnout was …

Evaluation Of Rotenone Mediated Α-Synuclein Spreading And Neurotoxicity In Intra-Striatal Injection Of Α-Synuclein Pff Model Of Parkinson’S Disease, Engila Khan

Theses

In the last 25 years, the prevalence of Parkinson’s Disease (PD) across the globe has doubled. Clinical manifestations of this progressive neurodegenerative disorder include motor symptoms such as tremors, bradykinesia, postural instability, etc., which occur due to selective loss of dopaminergic neurons in the Substantia nigra (SNC) in the brain. The histopathological feature of PD is the presence of intra-neuronal aggregates of proteins called Lewy bodies, a major constituent of which is α-synuclein (α-syn).

Epidemiological studies to date have reported a connection between exposure to environmental neurotoxins such as Rotenone (a mitochondrial complex 1 inhibitor) and increased risk of PD …

The Association Between Added Sugar And Abdominal Obesity In Adults, Noora Salem Alhammadi

Theses

Excessive body fat accumulation is a complicated medical condition known as obesity. Obesity increases the risk of chronic diseases including type 2 diabetes mellitus, cardiovascular disease, and several types of cancer. Numerous studies have shown that adults who regularly consume added sugar, mostly from sugar sweetened beverages, are more likely to be overweight or obese and/or abdominal obesity, however results remain controversial. The primary objective was to evaluate the relationship between Greek adults’ consumption of added sugar and abdominal obesity. The primary outcome was to investigate the intakes of added sugars in relation to weight status, fat mass, and specific …

Exploring Food And Physical Activity Behaviours Of Adolescents After Bariatric Surgery: A Qualitative Study, Baraa Osama Alries

Theses

In recent years, both globally and in the United Arab Emirates, adolescent obesity has emerged as a severe public health concern. Bariatric surgery is a viable treatment for adolescent obesity. However, an equally important aspect is examining the lifestyle changes, specifically concerning dietary habits and physical activity after this surgical intervention. Moreover, there is limited research on the postoperative nutrition-related nutritional and physical activity behaviors of adolescents after bariatric surgery globally, regionally, and in the UAE. The main aim of this study was to explore barriers and facilitators of diet and physical activity regimens of adolescents who had undergone bariatric …

Maternal And Perinatal Outcomes Of Women With Vaginal Birth After Cesarean Section Compared To Repeat Cesarean Birth In Select South Asian And Latin American Settings Of The Global Network For Women's And Children's Health Research, Lester Figueroa, Margo Harrison, Manolo Mazariegos, Shivaprasad Gouda, Avinash Kavi, Richard Derman, Archana Patel, Prabir Das, Sarah Saleem, Farnaz Naqvi

Community Health Sciences

Objective: Our objective was to analyze a prospective population-based registry including five sites in four low- and middle-income countries to observe characteristics associated with vaginal birth after cesarean versus repeat cesarean birth, as well as maternal and newborn outcomes associated with the mode of birth among women with a history of prior cesarean.
Hypothesis: Maternal and perinatal outcomes among vaginal birth after cesarean section will be similar to those among recurrent cesarean birth.
Methods: A prospective population-based study, including home and facility births among women enrolled from 2017 to 2020, was performed in communities in Guatemala, India (Belagavi and Nagpur), …

An Examination Of The Association Between Sleep Quality And Psychological Distress Among University Students In The Middle East: A Cross-Sectional Correlational Study, Ayesha Saeed Alsuwaidi

Theses

Literature reviews have revealed that there are limited studies on sleep quality in the United Arab Emirates (UAE) and that few studies are available in the Middle Eastern region. The objective of this study was to examine the association between sleep quality and psychological distress among university students in the Middle East. A correlational cross-sectional design was determined, and a self-administered online questionnaire was used. The electronic survey was circulated amongst students on campus and received 435 responses from three universities namely, Menoufia University in Egypt, Sultan Qaboos University in the Sultanate of Oman, and United Arab Emirates University in …