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2023

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Full-Text Articles in Medicine and Health Sciences

Molecular Detection Of Canine And Feline Hemotropic Mycoplasmas In Northern Vietnam, Bui Thi Huyen Thuong Jan 2023

Molecular Detection Of Canine And Feline Hemotropic Mycoplasmas In Northern Vietnam, Bui Thi Huyen Thuong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hemoplasma is commonly used to refer to hemotropic Mycoplasma bacterial species belonging to the genus Mycoplasma that can attach to the surface of red blood cells, potentially leading to hemolytic anemia. These organisms can infect a wide range of mammals, including companion animals and humans worldwide. Specifically for companion animals, two main hemoplasma species can infect dogs, and three major species can infect cats including Mycoplasma haemocanis, Candidatus Mycoplasma haematoparvum, Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, and Candidatus Mycoplasma turicensis, respectively. Currently, there is a lack of research data regarding hemoplasma infections in dogs and cats in Vietnam. Therefore, this study …


Student Response To Varied Instructional Methods In Level I Fieldwork Experiences, Camille Cj Turner Jan 2023

Student Response To Varied Instructional Methods In Level I Fieldwork Experiences, Camille Cj Turner

Theses and Dissertations

This applied dissertation was designed to investigate student responses to three different instructional strategies used to fulfill level I fieldwork requirements: traditional in-clinic rotation, a combination of virtual simulation and traditional in-clinic rotations, and virtual simulation. A multi-decade occupational therapy (OT) fieldwork shortage was exacerbated by the COVID-19 pandemic, in which OT education programs struggled to provide accreditation-required clinical education. Virtual simulation programs were utilized to fulfill some requirements, particularly more introductory-level fieldwork. Several cohorts of a Masters of Science in Occupational Therapy “bridge” program for licensed, practicing Certified Occupational Therapy Assistants and Physical Therapist Assistants were the subjects of …


Among Us: Impostor Syndrome And Barriers To Black Success, Deshayla M. Strachan Jan 2023

Among Us: Impostor Syndrome And Barriers To Black Success, Deshayla M. Strachan

Cardozo Journal of Equal Rights & Social Justice

Black women are going places-but they're not going into the practice of law. While law schools are becoming more diverse, the legal profession is not. The lack of diversity in the legal profession, coupled with existing implicit bias, causes heightened Impostor Syndrome in women, especially Black women, as well as women from other underrepresented groups. The harder the impostor feelings hit, the more difficult it is to retain women of color in the legal profession. Emotions associated with Impostor Syndrome (e.g., feelings of insufficiency) begin upon entry into the legal profession, as many roadblocks prevent marginalized groups from gaining admission …


Landscaping Wellness At Work: A Participatory Model For Worker-Centered Health, Anya Helena Piotrowski Jan 2023

Landscaping Wellness At Work: A Participatory Model For Worker-Centered Health, Anya Helena Piotrowski

Antioch University Dissertations & Theses

This study contributes to a body of scholarship that demonstrates the benefits and need of employee-driven and defined wellness at work processes. This participatory action research study brought together a team of employees within a remote-work, start-up organization to define and design a process for implementing wellness at work for their organization. Through a participatory process that allowed outcomes to emerge from the group, employees identified opportunities to foster embodied wellness in their organization in three core areas: organizational, personal, and cross-boundary initiatives. Through a reflective collaboration, employees generated ideas and developed a plan to address employee-identified priorities that will …


Relationships Among Trait Mindfulness, Self-Compassion, And Compassion Fatigue In Mental Health Professionals Working With Clients With A Terminal Illness, Christen Aiguier Jan 2023

Relationships Among Trait Mindfulness, Self-Compassion, And Compassion Fatigue In Mental Health Professionals Working With Clients With A Terminal Illness, Christen Aiguier

Antioch University Dissertations & Theses

This quantitative study explores the relationships among trait mindfulness, self-compassion, and compassion fatigue (CF) in mental health professionals working with clients with a terminal illness. The Five-Facet Mindfulness Questionnaire (FFMQ), Self-Compassion Scale, and Quality of Life Version 5 were used to explore these facets through linear multiple regression analysis. The Reactions to Research Participation Questionnaire–Revised was used to explore the cost–benefit ratio based on participant perceptions of the research experience. Participants (N = 43) self-selected from emailed invitations sent to members of professional organizations. Data was analyzed using multiple linear regression. Significant correlations included individual relationships between elevated trait mindfulness …


The Moderating Effects Of Clinical Videoconferencing On Therapeutic Alliance And Treatment Outcomes Among Substance Use Disorder Treatment Populations During The Covid-19, Seon W. Kim Jan 2023

The Moderating Effects Of Clinical Videoconferencing On Therapeutic Alliance And Treatment Outcomes Among Substance Use Disorder Treatment Populations During The Covid-19, Seon W. Kim

Antioch University Dissertations & Theses

This study aimed to contribute to understanding the relationship between therapeutic alliance (TA) and treatment outcome (TO) when comparing conventional (in-person treatment, IPT) with clinical videoconference-delivered treatment models in substance use disorder populations (SUD) during a global pandemic. Also, noting the importance of marital and family relationships in the treatment of substance use disorders, this study explored how marital status influenced the interaction of the therapeutic alliance and treatment outcomes. Utilizing the secondary data collected from an outpatient SUD treatment facility, this quantitative study conducted a moderated linear regression and moderated binary logistic regression to analyze the data. The results …


Dentists’ Perspective On Using Text And Video Consultation To Improve Self-Study For The Modified Complete Denture Technique, Nutnicha Punyakornwong Jan 2023

Dentists’ Perspective On Using Text And Video Consultation To Improve Self-Study For The Modified Complete Denture Technique, Nutnicha Punyakornwong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Complete edentulism has an adverse effect on the health and quality of life of older adults. However, patients frequently waited for years to receive treatment by prosthodontists. Simplified method could enable general dentists to treat edentulism efficiently. Tele-dentistry provides an approach for coaching general dentists in remote regions. In order to assist general dentists practicing the modified complete denture method, this study evaluated the learning outcomes of non-interactive and interactive self-study that used text and videoconferences. Participants were general dentists who had fewer than five years of experience. They were divided into non-interactive or interactive self-study group and received a …


Effect Of Simvastatin On Stem Cell Isolated From Apical Papilla (Scap) In Vitro, Paak Rewthamrongsris Jan 2023

Effect Of Simvastatin On Stem Cell Isolated From Apical Papilla (Scap) In Vitro, Paak Rewthamrongsris

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background and Objective: Simvastatin, known for lipid-lowering, shows promise in modulating stem cell behavior. This research investigates simvastatin's impact on apical papilla stem cells (SCAPs) in vitro. Methods: SCAPs were isolated, characterized, and exposed to varying simvastatin doses. Viability and proliferation were assessed with LIVE/DEAD and MTT assays. Cell cycle and apoptosis were examined via flow cytometry, and migration capacity was evaluated through scratch tests. Alizarin Red S staining and qPCR were used for odonto/osteogenic differentiation analysis. Results: Simvastatin reduced SCAP proliferation on days 3 and 7 and decreased colony size and density. Enhanced apoptosis and increased G0 subpopulation were …


Microencapsulation Of Lactobacillus Plantarum Mb001 And Its Probiotic Effect On Growth Performance And Gut Integrity Of Broile Rs, Sasi Vimon Jan 2023

Microencapsulation Of Lactobacillus Plantarum Mb001 And Its Probiotic Effect On Growth Performance And Gut Integrity Of Broile Rs, Sasi Vimon

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this work were 1) to study the preparation and characterization of LPMB001/AG-AL, 2) todetermine the characteristics, stability and viability of LPMB001/AG-AL against simulated gastrointestinal tract, high temperature and storage conditions and 3) To evaluate the supplementation of LPMB001/AG-AL on growth performance,ileal digestibility, intestinal morphology and microbiome in broiler chickens. The present work declared microcapsule networks based on polymer matrices (sodium alginate, AL and agar, AG) and charges under ionic crosslink aw emulsion to encapsulate probiotics for extensive stability in adverse conditions. The microcapsule was studied on physicochemicalcharacteristics, swelling efficiency as well as release pertormance and viability under …


Expression Of Proteins Mediating Pulmonary Hypertension In Dogs Affected With Degenerative Mitral Valve Disease, Siriwan Sakarin Jan 2023

Expression Of Proteins Mediating Pulmonary Hypertension In Dogs Affected With Degenerative Mitral Valve Disease, Siriwan Sakarin

Chulalongkorn University Theses and Dissertations (Chula ETD)

Pulmonary hypertension (PH) is defined by an abnormal elevation in pressure within pulmonary vasculature, often associated with degenerative mitral valve disease (DMVD) in dogs. While histopathological changes in the pulmonary arteries, known as pulmonary arterial remodeling, have been documented in human patients with PH, these alterations in DMVD dogs with PH have not been published. Proteomics, a potent method for exploring the entire protein complement of a biological sample, has emerged as a valuable tool for identifying PH-specific proteins, potentially serving as biomarkers for diagnosis and enhancing understanding of PH pathogenesis in DMVD dogs. This study aimed to evaluate the …


Screening Of Lactate Utilizing Bacteria And Their Beneficial Properties To Improve Energy Balance, Production And Ruminal Fermentation In Crossbred Dairy Goats, Saranporn Poothong Jan 2023

Screening Of Lactate Utilizing Bacteria And Their Beneficial Properties To Improve Energy Balance, Production And Ruminal Fermentation In Crossbred Dairy Goats, Saranporn Poothong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Sixty-three strains were isolated from ruminal fluid of crossbred dairy goats. Based on phenotype and 16S rRNA gene, sixteenbacterial groups were identified and two novel species of Selenomonas were purposed in this study. The strain mPRGC5 was purposed as Selenomonas runimis and the strain mPRGC8 was named Selenomonas caprae. The antimicrobial activity of all the strains was determined.Ligilactobacillus salivarius MP3 showed antibacterial activity against Cutibacterium acnes subsp. acnes DSM 1897' and Kocuria thizophila Mill. The antimicrobial substance was genomically identified as enterolysin A. Furtherniore, L. salivarius MP3 presented probiotic properties and the potential antimicrobial activity against pathogens. The fourteen strains …


Application Of Anti-Müllerian Hormone As An Indicator For Ovarian Reserve And Ovarian Response To Hormonal Stimulation In Domestic Cats And Wild Felids, Sittat Chumsri Jan 2023

Application Of Anti-Müllerian Hormone As An Indicator For Ovarian Reserve And Ovarian Response To Hormonal Stimulation In Domestic Cats And Wild Felids, Sittat Chumsri

Chulalongkorn University Theses and Dissertations (Chula ETD)

Serum anti-Müllerian hormone (AMH) has been utilized to predict ovarian reserve and select suitable candidates for natural mating and artificial insemination (AI) in domestic animals. However, research on serum AMH concentration as a fertility marker in feline species remains limited. This study aims to investigate: 1) the possibility of using serum AMH levels to determine the number of follicles in domestic cats; 2) the validation of the AMH Gen II ELISA for measuring serum AMH levels in fishing cats, leopard cats and clouded leopards; and 3) the relationship between serum AMH levels and ovarian responsiveness in clouded leopards. In Study …


Contraception In Free-Ranging Long-Tailed Macaques With Special Focus On Anesthesia Management And Development Of Nanobody Targeting Extracellular Domain Of Follicular Stimulating Hormone Receptors, Pakpoom Navanukraw Jan 2023

Contraception In Free-Ranging Long-Tailed Macaques With Special Focus On Anesthesia Management And Development Of Nanobody Targeting Extracellular Domain Of Follicular Stimulating Hormone Receptors, Pakpoom Navanukraw

Chulalongkorn University Theses and Dissertations (Chula ETD)

The overlapping presence of free-ranging long-tailed macaques (Macaca fascicularis) and humans in Thailand and ฆSoutheast Asia resulted in physical violence, ravaging and zoonotic disease transmission. To mitigate these detriments, the synergy of surgical and nonsurgical contraception is essential for imperative population control. This thesis aimed to: 1) enhance animal welfare and safety of macaques undergoing surgical contraception by applying multimodal anesthesia practices; 2) generate alternative non-surgical contraceptives against the extracellular domain (ECD) of follicular stimulating hormone receptors (FSHr) in long-tailed macaques; 3) formulate nano/microstructured microspheres containing anti-FSHr scFv for oral delivery and determine the pharmacokinetics and bioavailabilityIn Study 1, the …


De Novo Assembly Of The Reference Genome, Genetic Variations And Serum Proteomics Of Eld's Deer (Rucervus Eldii), Vichayanee Pumpitakkul Jan 2023

De Novo Assembly Of The Reference Genome, Genetic Variations And Serum Proteomics Of Eld's Deer (Rucervus Eldii), Vichayanee Pumpitakkul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Eld’s deer is a conserved wildlife species in Thailand. Due to the limited population group in captivity, Eld’s deer is facing a crisis of low genetic diversity, particularly among the captive Siamese Eld’s deer (SED) subspecies. This study aimed to construct genomes for a SED and a Burmese Eld’s deer (BED) for the first time and use genome-wide single nucleotide polymorphisms (SNPs) to assess the genetic purity and inbreeding status of 35 SED and 49 BED with limited pedigree data. Results revealed that the 2 subspecies diverged approximately 1.26 million years ago. All SED are purebred, whereas a small proportion …


Utilization Of Testosterone-Encapsulated Nanoparticles For Masculinization Of Red Tilapia (Oreochromis Sp.), Jakarwan Yostawonkul Jan 2023

Utilization Of Testosterone-Encapsulated Nanoparticles For Masculinization Of Red Tilapia (Oreochromis Sp.), Jakarwan Yostawonkul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Tilapia (Oreochromis sp.) is a freshwater fish that is highly popular for aquaculture in Thailand. To achieve high yields, good growth rates, and better feed conversion rates, 17-alpha-methyltestosterone are commonly used to induce male sex in farmed tilapia. However, it has been found in previous studies that these synthetic hormones have low water solubility and limited absorption capabilities, leading to excessive hormone use. In this research, lipid-based nanoparticles, a widely used drug delivery technology, were employed to enhance the efficiency of synthetic hormones with low water solubility. This improved the dispersion of hormones in water, enhanced their absorption in the …


Genome Characterization And Development Of Inactivated Vaccine Against Scale Drop Disease Virus (Sddv) In Asian Sea Bass (Lates Calcarifer), Putita Chokmangmeepisarn Jan 2023

Genome Characterization And Development Of Inactivated Vaccine Against Scale Drop Disease Virus (Sddv) In Asian Sea Bass (Lates Calcarifer), Putita Chokmangmeepisarn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Scale drop disease virus (SDDV) is a significant pathogen affecting Asian sea bass (Lates calcarifer) in Southeast Asia, causing scale drop syndrome (SDS) and resulting in high mortality and substantial economic losses in aquaculture. Recently, SDDV has been reported in Asian sea bass farms throughout the Asia-Pacific region including Thailand, Indonesia, Malaysia, Singapore, and China. This study employed metagenomic methods to analyze bacterial and viral communities in infected fish tissues from Southeast Asia, leading to the recovery and characterization of the complete genome of SDDV strain TH7_2019. The genome, comprising 131 kb with 134 putative ORFs, showed high amino acid …


Characterization Of Antimicrobial Resistance And Virulence Factors In Multidrug-Resistant Extraintestinal Pathogenic Escherichia Coli Isolated From Canine Urinary Tract, Reproductive Tract And Bloodstream Infections, Parinya Sroithongkham Jan 2023

Characterization Of Antimicrobial Resistance And Virulence Factors In Multidrug-Resistant Extraintestinal Pathogenic Escherichia Coli Isolated From Canine Urinary Tract, Reproductive Tract And Bloodstream Infections, Parinya Sroithongkham

Chulalongkorn University Theses and Dissertations (Chula ETD)

Despite extensive characterization of uropathogenic Escherichia coli (UPEC) causing urinary tract infections (UTIs), the genetic background of non-urinary extraintestinal pathogenic E. coli (ExPEC) in dogs, such as those causing canine pyometra, prostatic abscesses (PAs), and bloodstream infections (BSIs), remains inadequately understood. This study characterized the virulence determinants of 101 E. coli isolates from canine pyometra (n=61), PAs (n=38), and BSIs (n=2). The analysis revealed a stronger association of pyometra strains with UPEC compared to PA strains. Forty-one isolates were resistant to third-generation cephalosporins and/or fluoroquinolones, with 14 being extended-spectrum β-lactamase producers and carrying blaCTX-M. Whole-genome sequencing was performed on 10 …


Development And Evaluation The Efficacy Of A Water-Soluble Probiotic Microencapsulation Prototype For Pediococcus Acidilactici Isolated From Broiler Chickens, Ratchnida Kamwa Jan 2023

Development And Evaluation The Efficacy Of A Water-Soluble Probiotic Microencapsulation Prototype For Pediococcus Acidilactici Isolated From Broiler Chickens, Ratchnida Kamwa

Chulalongkorn University Theses and Dissertations (Chula ETD)

Probiotics are live bacteria that can be given orally to promote gastrointestinal health. A limitation of probiotic use is their diminished efficiency following the loss of live cells during high-temperature processing and storage. Microencapsulation technology has been created to protect probiotic cells, preserve their viability, and maintain their efficacy following manufacture. The aim of this study was to evaluate the effectiveness of a water-soluble microencapsulation method using gum Arabic (GA) and skim milk (SKM) over a three-month storage period following processing. Four strains of Pediococcus acidilactici (BYF26, BYF20, BF9, and BF14) that were typical lactic acid bacteria (LAB) strains isolated …


Novel Vaccination Strategy Against Vibrio Harveyi Infection In Asian Seabass (Lates Calcarifer) Using A Chitosan – Oxygen Nanobubble - Vaccine Complex, Nguyen Giang Thu Lan Jan 2023

Novel Vaccination Strategy Against Vibrio Harveyi Infection In Asian Seabass (Lates Calcarifer) Using A Chitosan – Oxygen Nanobubble - Vaccine Complex, Nguyen Giang Thu Lan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Vibriosis is a bacterial disease caused by Vibrio harveyi (V. harveyi; Vh ) that poses a substantial threat to Asian seabass (Lates calcarifer) aquaculture. In this study, we investigated alternative approaches to conventional injection vaccination for prevention of V. harveyi in Asian seabass. The first approach involved an immersion prime with heat-inactivated V. harveyi vaccine, followed by two oral booster doses (day 14-18 and day 28-32). Immunized fish demonstrated higher expression levels of immune genes (i.e. TNFα, IL1β, CD4, CD8, and IgM) following the immersion prime and the first oral booster dose, peaking at 14 and 28 days post vaccination …


Farrowing Performances And Piglet Characteristics In Highly Prolific Sows In Tropical Environment: Impact Of Aging, Ambient Temperature And Humidity Within The Barn, And Feeds, Yosua Kristian Adi Jan 2023

Farrowing Performances And Piglet Characteristics In Highly Prolific Sows In Tropical Environment: Impact Of Aging, Ambient Temperature And Humidity Within The Barn, And Feeds, Yosua Kristian Adi

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hyperprolific sows have been widely distributed in the global swine industry, including Thailand. Therefore, factors affecting the farrowing performance and piglet characteristics of these sows were investigated to establish effective management practices, especially in tropical climates. Moreover, strategies to enhance sow colostrum production and expedite the farrowing process were also explored. Additionally, deep insight into the effect of aging on farrowing performance, particularly farrowing duration, through investigation of reproductive organ morphology and oxytocin receptor expression on uterine tissue was conducted. The study revealed that sows with a high number of piglets born per litter, a high parity number, and parturition …


Assessment Of Longitudinal Systolic Funcion By Using Tissue Motion Annular Displacement In Hypertrophic Cardiomyopathy Cats, Nadthagarn Glaewketgarn Jan 2023

Assessment Of Longitudinal Systolic Funcion By Using Tissue Motion Annular Displacement In Hypertrophic Cardiomyopathy Cats, Nadthagarn Glaewketgarn

Chulalongkorn University Theses and Dissertations (Chula ETD)

In humans, tissue motion annular displacement (TMAD) providesresponsive and accurate assessment on longitudinal systolic function. The aim ofthis study is to investigate the LV longitudinal systolic function in hypertrophiccardiomyopathy (HCM) and control cats by using TMAD. The study includes 26control cats and 21 HCM cats. Global TMAD were not influence by breed, sex, age,and heart rate. Global TMAD and % Global TMAD significantly decreased in theHCM group (2.86±0.86 mm and 11.46±3.37%) when compared to control group(3.95±0.89 mm and 16.12±2.94%) (p<0.001 and <0.001), suggesting LV longitudinalsystolic dysfunction in HCM cats. LV fractional shortening (LVFS) showed nodifference between the control (52.76±11.63%) and HCM stage group(59.80±13.51%) (p=0.061). Indicate that TMAD is a sensitive technique foridentifying LV longitudinal systolic dysfunction. Global TMAD and % global TMADhad a significant correlation with global longitudinal strain (GLS). Therefore, TMADcan be used to evaluate longitudinal systolic function in HCM. The reliability test ofglobal TMAD and % global TMAD were considered moderate. In conclusion, globalTMAD and % global TMAD was significantly decreased in cats with HCM comparedwith the control group and was considered as sensitive and repeatable techniquefor evaluating LV longitudinal systolic dysfunction in cats with HCM


Investigating Of Candidate Genes Affecting Milk Production In Dairy Cattle Using Systematic Review And Whole Genome Sequencing Database, Xiaoxian Su Jan 2023

Investigating Of Candidate Genes Affecting Milk Production In Dairy Cattle Using Systematic Review And Whole Genome Sequencing Database, Xiaoxian Su

Chulalongkorn University Theses and Dissertations (Chula ETD)

Milk production traits in dairy cattle, such as milk yield, fat content, and protein levels, are pivotal to the economic success of the dairy industry. These traits not only determine the quality and quantity of milk produced but also directly impact the profitability of dairy operations. Consequently, a deep understanding of the genetic architecture underlying these traits is essential for the development of effective breeding programs aimed at enhancing milk production and quality. The purpose of this study is to identify potential candidate genes related to milk production in Thai dairy cattle through systematic review of genome wide association study …


Safety Assessment Of Lactic Acid Bacteria (Lab) As Potential Probiotics For Thai Swine And Poultry: A Whole Genome Sequencing Approach, Yuda Disastra Jan 2023

Safety Assessment Of Lactic Acid Bacteria (Lab) As Potential Probiotics For Thai Swine And Poultry: A Whole Genome Sequencing Approach, Yuda Disastra

Chulalongkorn University Theses and Dissertations (Chula ETD)

The standard criteria for determining the safety of bacteria used as probiotics do not exist at this time. The objective of this investigation was to assess the feasibility and safety of eight lactic acid bacteria (LAB) strains employed as probiotics. Of these, four were Pediococcus acidilactici strains (IAF6519, IAF5919, AF2519, and AF2019), one Ligilactobacillus salivarius AF2319 derived from chickens and Pediococcus acidilactici P72N and Lactiplantibacillus plantarum L25F and L22F obtained from pigs. Phenotypic investigation was performed on biochemical features, antimicrobial resistance patterns, and hemolytic activity. P. acidilactici AF2519 and AF2019 strains were resistant to erythromycin and clindamycin, Ligilactobacillus salivarius strain …


Dynamic Community Of Strongyle Nematodes And Ivermectin Resistant Evidence Of Domesticated Horses In Thailand, Mohamed Hossameldein Abdelfatah Mohamed Hamad Jan 2023

Dynamic Community Of Strongyle Nematodes And Ivermectin Resistant Evidence Of Domesticated Horses In Thailand, Mohamed Hossameldein Abdelfatah Mohamed Hamad

Chulalongkorn University Theses and Dissertations (Chula ETD)

Strongylids are a group of parasitic nematodes that infect horses and other equids worldwide, with a potential negative impact on their health and performance. There is no available research that has studied strongylids infection in domesticated horse populations nor assessed the effectiveness of ivermectin in treating these parasites in Thailand. This thesis, therefore, aimed to comprehensively investigate strongyle parasite intensity and factors influencing egg shedding patterns. Additionally, it utilized nemabiome metabarcoding approach to identify strongylid species, analyse ecological diversity, and assess co-occurrence patterns within the studied horse populations. Furthermore, it employed faecal egg count reduction (FECR) test to assess the …


Prioritization Of Candidate Genes For Mastitis Resistance Trait In Genome-Wide Association Studies (Gwas) Utilizing Multiple Methodologies In Thai Dairy Cattle, Nhu Le Uyen Vo Jan 2023

Prioritization Of Candidate Genes For Mastitis Resistance Trait In Genome-Wide Association Studies (Gwas) Utilizing Multiple Methodologies In Thai Dairy Cattle, Nhu Le Uyen Vo

Chulalongkorn University Theses and Dissertations (Chula ETD)

Mastitis affects milk yield in dairy cattle worldwide, leading to economic losses. Recognized as a polygenic trait, mastitis resistance is influenced by genetic, environmental, and physiological factors. This study aimed to enhance the genetic architecture and selection of the candidate for mastitis resistance traits in Thai dairy cattle by several methods. The study consisted of two parts. In Part 1, the study is divided into 1A) collecting genes from a systematic review of published GWAS, 1B) Analyzing the gene list with the Thai dairy cattle whole genome sequencing database, and 1C) Performing pathway enrichment analysis to identify candidate genes. Further …


Reliability Of Cardiac Measurement By Vertebral Heart Score Among Different Thoracic Types Of Dogs, Suphat Soeratanapant Jan 2023

Reliability Of Cardiac Measurement By Vertebral Heart Score Among Different Thoracic Types Of Dogs, Suphat Soeratanapant

Chulalongkorn University Theses and Dissertations (Chula ETD)

Vertebral heart score (VHS) is a radiographic tool that widely use in veterinary clinical field for evaluating the heart sizeby measure a heart long and short axes and neutralize with vertebral length. However, VHSs among canine breeds are varied from thereference value. Thoracic type is one of the factors that affect to VHS because the shape of canine thoracic type is the structuralvariations that affect heart orientation. Subsequently, it affects to VHS value in thoracic radiographs. Computed tomography (CT) is anadvanced diagnostic tool that provide a multiplane image without superimposition effect. Therefore, CT provide more accurate heartorientation and its evaluation …


Impact Of Probiotic Supplementation In Lactating Sows On Immune And Oxidative Stress Biomarkers, Short-Chain Fatty Acids, Piglet Performance, And Fecal Microbiome, Chutikan Srisang Jan 2023

Impact Of Probiotic Supplementation In Lactating Sows On Immune And Oxidative Stress Biomarkers, Short-Chain Fatty Acids, Piglet Performance, And Fecal Microbiome, Chutikan Srisang

Chulalongkorn University Theses and Dissertations (Chula ETD)

This clinical trial aimed to investigate the effects of probiotic supplementation in lactating sows on their serum immunoglobulin levels, milk yield, serum malondialdehyde (MDA), fecal short-chain fatty acid levels, piglet performance, and fecal microbiome. The research was conducted at a commercial swine breeding herd in central Thailand. The study included 109 Canadian Landrace × Yorkshire sows, with parity numbers ranging from 1 to 7. The sows were divided into two groups based on their parity numbers: control (n = 61) and treatment (n = 48). The control group sows received a conventional commercial lactation diet without any antibiotic supplementation, starting …


ผลของการให้ข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วมต่อพฤติกรรมการดูแลตนเองของผู้ป่วยเด็กวัยเรียนโรคหืด, ศศิวิมล ลิ้มวัฒนะ Jan 2023

ผลของการให้ข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วมต่อพฤติกรรมการดูแลตนเองของผู้ป่วยเด็กวัยเรียนโรคหืด, ศศิวิมล ลิ้มวัฒนะ

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยกึ่งทดลองครั้งนี้มีวัตถุประสงค์เพื่อเปรียบเทียบพฤติกรรมการดูแลตนเองของผู้ป่วยเด็กวัยเรียนโรคหืด ในกลุ่มที่ได้รับการให้ข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วมกับกลุ่มที่ได้รับการพยาบาลตามปกติ ใช้แนวคิดการพัฒนาความสามารถในการดูแลตนเองของโอเร็ม (2001) กลุ่มตัวอย่าง คือ ผู้ป่วยเด็กวัยเรียนโรคหืดที่มีอายุระหว่าง 6-12 ปีและครอบครัวที่เข้ารับการรักษาที่คลินิกโรคหืด โรงพยาบาลดำเนินสะดวก โรงพยาบาลบ้านโป่งและโรงพยาบาลโพธาราม จำนวน 42 คน จัดกลุ่มตัวอย่าง 21 คนแรกเข้ากลุ่มควบคุมก่อนแล้วจัดกลุ่มตัวอย่าง 21 คนหลังเข้ากลุ่มทดลอง โดยจับคู่เพศ อายุและระดับความรุนแรงของโรค กลุ่มควบคุมได้รับการพยาบาลปกติ กลุ่มทดลองได้รับการให้ข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วม วัดพฤติกรรมด้วยแบบสอบถามพฤติกรรมการดูแลตนเองของผู้ป่วยวัยเรียนโรคหืด มีค่าความตรงตามเนื้อหาเท่ากับ 0.80 และมีค่าความเที่ยงเท่ากับ 0.84 วิเคราะห์ข้อมูลโดยหาค่าเฉลี่ย ร้อยละ และสถิติทดสอบที ผลการวิจัยพบว่าพฤติกรรมการดูแลตนเองของผู้ป่วยเด็กวัยเรียนโรคหืดภายหลังได้รับการให้ข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วมดีกว่าก่อนได้รับข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วมอย่างมีนัยสำคัญทางสถิติที่ระดับ .05 และพฤติกรรมการดูแลตนเองของผู้ป่วยเด็กวัยเรียนโรคหืดในกลุ่มที่ได้รับการให้ข้อมูลผ่านสื่อแอปพลิเคชันโดยครอบครัวมีส่วนร่วมดีกว่ากลุ่มที่ได้รับการพยาบาลตามปกติอย่างมีนัยสำคัญทางสถิติที่ระดับ .05


The Scale Development Of Quality Of Care In Nursing Home, Chaowarit Ngernthaisong Jan 2023

The Scale Development Of Quality Of Care In Nursing Home, Chaowarit Ngernthaisong

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study is an exploratory sequential mixed methods consisting of two phases. The first phase employed qualitative descriptive research and the second phase was descriptive research for scale development. There are three research objectives, methods, and results as follows: Objective 1: To describe the major themes of outcomes of quality of care in nursing home. Qualitative descriptive research was conducted by interviewing 10 registered nurses working in nursing homes. Data was analyzed by using content analysis. The results showed six major themes of outcomes of quality of care in nursing home consisting of; 1) Physical well-being, 2) Psychological well-being, 3) …


ผลของการฝึกแบบผสมผสานระหว่างการออกกำลังกายและการฝึกพุทธิปัญญาต่อความสามารถการควบคุมความตั้งใจและปริมาณเซรั่มบีดีเอ็นเอฟของนักกีฬาอีสปอร์ตชาย, เตชิต เลิศเอนกวัฒนา Jan 2023

ผลของการฝึกแบบผสมผสานระหว่างการออกกำลังกายและการฝึกพุทธิปัญญาต่อความสามารถการควบคุมความตั้งใจและปริมาณเซรั่มบีดีเอ็นเอฟของนักกีฬาอีสปอร์ตชาย, เตชิต เลิศเอนกวัฒนา

Chulalongkorn University Theses and Dissertations (Chula ETD)

ความตั้งใจเป็นทักษะที่สำคัญในการเล่นกีฬาอีสปอร์ตโดยส่งผลต่อการตัดสินใจ เวลาปฏิกิริยา และทักษะอื่น ๆ ที่เกี่ยวข้อง ตลอดจนถึงความสามารถในการเล่นเกมโดยรวม จึงเป็นไปได้ว่าการพัฒนาความสามารถด้านความตั้งใจอาจส่งผลต่อประสิทธิภาพในการเล่นกีฬาอีสปอร์ตได้การวิจัยในครั้งนี้จึงมุ่งศึกษาลักษณะความสามารถความตั้งใจในกีฬาอีสปอร์ต โดยแบ่งเป็นสองการศึกษา ดังนี้การศึกษาที่ 1 มีวัตถุประสงค์เพื่อเปรียบเทียบความสามารถความตั้งใจระหว่างนักกีฬาอีสปอร์ตมืออาชีพและผู้เล่นอีสปอร์ตระดับมหาวิทยาลัย โดยทำการทดสอบความสามารถด้านความตั้งใจในนักกีฬาอีสปอร์ตมืออาชีพ 8 คนและผู้เล่นอีสปอร์ตระดับมหาวิทยาลัย 8 คนจากนักกีฬาอีสปอร์ตประเภทโมบา(MOBA) โดยใช้การทดสอบความตั้งใจแบบกระพริบ ทดสอบการค้นหาด้วยสายตา และการตอบสนองต่อสัญญาณไฟปฏิกิริยา ผลการทดลองพบว่ากลุ่มนักกีฬาอีสปอร์ตมืออาชีพมีอัตราการตอบสนองถูกต้องสูงกว่าอย่างมีนัยสำคัญทางสถิติในการทดสอบความตั้งใจแบบกระพริบ (p = .033) และมีเวลาปฏิกิริยาตอบสนองเร็วกว่าอย่างมีนัยสำคัญทางสถิติในการทดสอบการค้นหาด้วยสายตา (p = .002) ในส่วนของการทดสอบตอบสนองต่อสัญญาณไฟปฏิกิริยาไม่พบว่ามีความแตกต่างกันการศึกษาที่ 2 มีวัตถุประสงค์เพื่อเปรียบเทียบผลของการฝึกแบบผสมผสานระหว่างการออกกำลังกายและการฝึกพุทธิปัญญาต่อความสามารถด้านความตั้งใจและปริมาณเซรั่มบีดีเอ็นเอฟ โดยทำการทดลองในนักกีฬาอีสปอร์ตที่ผ่านการแข่งขันในรายการ CU Open จำนวน 32 คน แบ่งเป็น 4 กลุ่ม ประกอบด้วยกลุ่มฝึกผสมผสานการออกกำลังกายและการฝึกพุทธิปัญญา (Physical-Cognitive Exercise ;PCE) กลุ่มฝึกออกกำลังกาย (Physical Exercise; PE),กลุ่มฝึกพุทธิปัญญา (Cognitive Exercise (CE),และกลุ่มควบคุม (C). โดยทำการฝึก 4 สัปดาห์ สัปดาห์ละ 2 ครั้ง ทำการทดสอบความตั้งใจแบบกระพริบ การค้นหาด้วยสายตา การตอบสนองต่อสัญญาณไฟปฏิกิริยา และวัดปริมาณเซรั่มบีดีเอ็นเอฟ ก่อนการทดลอง หลังการฝึกครั้งแรก และหลังการฝึก 4 สัปดาห์ ผลฉับพลันจากการฝึกพบว่า กลุ่ม PE และ CE มีอัตราการตอบสนองถูกต้องสูงกว่ากลุ่ม PCE และกลุ่มควบคุมอย่างมีนัยสำคัญทางสถิติ (p = .017, = .020 และ p < .001, < .001 ตามลำดับ) ในการทดสอบความตั้งใจแบบกระพริบ และกลุ่ม CE มีเวลาปฏิกิริยาในการตอบสนองเร็วกว่ากลุ่มอื่นๆอย่างมีนัยสำคัญทางสถิติ (p = .004) ในการทดสอบการค้นหาด้วยสายตา หลังการฝึก 4 สัปดาห์ กลุ่ม PCE PE และ CE มีอัตราการตอบสนองถูกต้องสูงกว่ากลุ่มควบคุมอย่างมีนัยสำคัญทางสถิติ (p = .028, .008, < .001 ตามลำดับ) ในการทดสอบความตั้งใจแบบกระพริบ และกลุ่ม PCE และ PE มีอัตราการตอบสนองถูกต้องมากกว่ากลุ่ม CE อย่างมีนัยสำคัญทางสถิติ (p = .021, .003 ตามลำดับ) ในการทดสอบการค้นหาด้วยสายตา แต่มีเวลาปฏิกิริยาในการตอบสนองที่ช้ากว่ากลุ่ม CE (p = .003, .004) ในส่วนของปริมาณเซรั่มบีดีเอ็นเอฟ หลังการฝึกครั้งแรกพบว่ากลุ่ม PE มีการเพิ่มขึ้นอย่างมีนัยสำคัญทางสถิติ (p = .004) และหลังการฝึก 4 สัปดาห์พบว่ากลุ่ม PCE และ PE มีปริมาณเซรั่มบีดีเอ็นเอฟเพิ่มขึ้นกว่าก่อนการทดลองอย่างมีนัยสำคัญทางสถิติ (p = .004, .024 ตามลำดับ)จากผลการทดลองพบว่านักกีฬาอีสปอร์ตมืออาชีพมีความสามารถความตั้งใจที่สูงกว่านักกีฬาอีสปอร์ตในระดับสมัครเล่น โดยการฝึกแบบผสมผสานการออกกำลังกายและการฝึกพุทธิปัญญาสามารถช่วยเพิ่มประสิทธิภาพความตั้งใจของนักกีฬาอีสปอร์ตในระดับสมัครเล่นได้ จึงอาจใช้เป็นแนวทางหนึ่งในการพัฒนาความสามารถความตั้งใจ และอาจช่วยเพิ่มความสามารถในการเล่นและแข่งขันกีฬาอีสปอร์ตได้ทางหนึ่ง