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Articles 24211 - 24240 of 27439
Full-Text Articles in Medicine and Health Sciences
High Energy Blue Light Induces Oxidative Stress And Retinal Cell Apoptosis, Jessica Malinsky
High Energy Blue Light Induces Oxidative Stress And Retinal Cell Apoptosis, Jessica Malinsky
Capstone Showcase
Blue light (BL) is a high energy, short wavelength spanning 400 to 500 nm. Found in technological and environmental forms, BL has been shown to induce photochemical damage of the retina by reactive oxygen species (ROS) production. Excess ROS leads to oxidative stress, which disrupts retinal mitochondrial structure and function. As mitochondria amply occupy photoreceptors, they also contribute to oxidative stress due to their selectively significant absorption of BL at 400 to 500 nm. ROS generation that induces oxidative stress subsequently promotes retinal mitochondrial apoptosis. BL filtering and preventative mechanisms have been suggested to improve or repair BL-induced retinal damage, …
Association Of Diabetes Prevalence With Labor Force Participation Rates In Kentucky Counties, Ryan Montgomery
Association Of Diabetes Prevalence With Labor Force Participation Rates In Kentucky Counties, Ryan Montgomery
MPA/MPP/MPFM Capstone Projects
Compared to other states in the USA, Kentucky has one of the highest rates of diagnosed diabetes and one of the lowest levels of labor force participation. This project employs a multivariable linear regression model to estimate the correlation between county-level diabetes prevalence and county-level labor force participation rates in Kentucky counties from 2015-2019, using publicly available data from the Centers for Disease Control’s Behavioral Risk Factor Surveillance System (BRFSS) and the U.S. Census Bureau’s American Community Survey (ACS). Labor force participation rates serve as the dependent variable and diabetes prevalence rates serve as the primary independent variable, alongside nine …
Transcranial Direct Current Stimulation (Tdcs) To Improve Lower Limb Motor Recovery Following Stroke: A Review And Study Proposal, Jessica Fantz-Sands
Transcranial Direct Current Stimulation (Tdcs) To Improve Lower Limb Motor Recovery Following Stroke: A Review And Study Proposal, Jessica Fantz-Sands
Scripps Senior Theses
Strokes are the result of restricted blood flow to particular areas of the brain classified by their cause. The neural damage they cause are of growing concern as the number of young adults experiencing strokes has increased by 11% in the last decade. Following stroke, there is an imbalance of inhibitory and excitatory neuronal activity, and disruption of neural networks. These changes lead to neuronal death and loss of synaptic connections that, depending on which part of the brain is affected, result in behavioral deficits such as weakness, limb hemiparesis, and loss of coordination, as well as speech and cognitive …
Crime, Illness, & Abolition: An Exploration Through The Connective Tissue Within The Pic/Mic Matrix, Laila Kent
Crime, Illness, & Abolition: An Exploration Through The Connective Tissue Within The Pic/Mic Matrix, Laila Kent
Scripps Senior Theses
This two part zine illuminates the shared mechanisms that construct and respond to ‘crime’, also define and treat illness in the US. Part 1 uncovers the status quo of our prison and health care system via the emergence of the The Prison-Industrial Complex (PIC), and The Medical-Industrial Complex (MIC). Through an exploration of the respective and overlapping histories, logics, and realities underlying the function of these systems, the mechanisms of individualism, objectification, and profiteering become strikingly clear. Part 2 breaks free of the status quo outlined in Part 1 by introducing abolition as the vision and strategy to heal from …
Utilizing Amr Surveillance Data To Analyze Trends In Escherichia Coli Antibiotic Resistance Levels In The South African Provinces Of Gauteng And The Eastern Cape, Celia Maris
Scripps Senior Theses
Antimicrobial resistant bacterial pathogens pose an ongoing threat to universal public health by causing more severe manifestations of infectious diseases, leading to an increase in healthcare expenditures and higher global mortality rates. Therefore, developing strategies to combat bacterial antimicrobial resistance (AMR) is vital for the future of human health. One promising strategy is through the utilization of AMR surveillance programs. This study focused on using AMR surveillance data from South Africa to analyze changes in Escherichia coli resistance levels to numerous antibiotics between January 2012 and December 2022 in Gauteng Province and the Eastern Cape Province. The study aimed to …
We Can Do This / Juntos Sí Podemos: A Critical Discourse Analysis Of Government-Sponsored Covid-19 Public Service Announcements (Psas) In English And Spanish, Katalina R. Peterson
We Can Do This / Juntos Sí Podemos: A Critical Discourse Analysis Of Government-Sponsored Covid-19 Public Service Announcements (Psas) In English And Spanish, Katalina R. Peterson
Scripps Senior Theses
Communication inequities are known to negatively impact people from socioeconomically and linguistically disadvantaged backgrounds during public health crises (Gomez-Aguinaga et al., 2021). In the United States, Hispanics—especially those who speak Spanish—have been among the communities most disproportionately affected by COVID-19 (National Center for Health Statistics, 2022). The pandemic has underscored the importance of understanding the linguistic and discursive strategies implemented by institutions entrusted with disseminating public health information to reach diverse audiences, especially the most vulnerable. This paper analyzes the linguistic practices used to create public service announcements (PSA) produced in English and Spanish by health agencies at both the …
Dementia And The Fragility Of Self: Navigating Ethical Considerations In Medical Decision-Making, Grace Sauers
Dementia And The Fragility Of Self: Navigating Ethical Considerations In Medical Decision-Making, Grace Sauers
Scripps Senior Theses
As the global population ages, the incidence of degenerative memory disorders such as Alzheimer's and dementia is expected to rise. The frequency of complex medical decision-making challenges for these patients will subsequently increase. It is now common practice for patients to provide advance directives outlining the care they wish to receive; in the case they are deemed incompetent to perform adequate decision making. However, patients with dementia occasionally express wishes contrary to those stated in their advance directives. This divergence creates ambiguity about which wishes should be honored and for who those wishes are being honored for. I aim to …
The Role Of Porn Literacy In Comprehensive Sex Education To Reduce Endorsements Of Gendered Sexual Violence And Support Healthy Adolescent Development, Kiana Harnish
Scripps Senior Theses
Due to stigmatization of sex and insufficient sexual education, modern-day adolescents rely on free online pornography as a source of education about sex and relationships. This thesis provides a review of the connections between adolescent porn use and the socialization of sexual violence (SV) and coercion against women, comprehensive sex education (CSE) and healthy adolescent sexual development, and porn literacy (PL) and sexual attitude or behavior changes. Porn literacy aims to equip adolescents with tools to critically analyze sexualied media and messages, to empower them to make informed decisions to engage or disengage with porn and their sexuality in a …
Mental Health Stigma In South Asians With Crohn’S Disease, Bansi Patel
Mental Health Stigma In South Asians With Crohn’S Disease, Bansi Patel
Scripps Senior Theses
Chronically ill individuals often face comorbid mental illnesses. Mental illness symptoms can cause their chronic illness symptoms to worsen; the converse is also true. Such is the case with Crohn’s disease (CD) patients. The present literature lacks research on the relationship between CD and mental illness symptoms. Additionally, the literature lacks chronically ill participants who are South Asian Americans (SAA). SAA often face more mental health stigma than their white peers which can worsen one’s mental illness symptoms. This study examines the impact that mental health symptoms have on the psychological distress faced by SAA who are diagnosed with CD. …
Efficacy Of Adapted Mindfulness-Based Stress Reduction Program In Treating Patients With Mild Traumatic Brain Injury, Kate Whipple
Efficacy Of Adapted Mindfulness-Based Stress Reduction Program In Treating Patients With Mild Traumatic Brain Injury, Kate Whipple
Scripps Senior Theses
Mindfulness-based stress reduction (MBSR) has been applied in many contexts, and has been found to be a helpful therapeutic intervention for people dealing with both mental and physical struggles. In recent years, studies exploring the effects of using MBSR in the neurorehabilitation people with traumatic brain injuries (TBIs) have emerged. However, these studies are primarily pilot studies with very few participants. This proposed study will explore whether an adapted version of the MBSR program is effective in reducing apathy and improving motivation to recover in participants with mild TBIs (mTBIs). The proposed study will have 76 participants and will uses …
Business And Psychological Aspects Of Viable Mental Health Digital Tools, Dar Bejerano
Business And Psychological Aspects Of Viable Mental Health Digital Tools, Dar Bejerano
Honors Program Theses
This study aims to understand the industry potential of the mental health mobile tool market and articulate how it intersects with consumer attitudes to determine the viability of digital tools in the mental health space. Themes regarding the prevalence of mental health concerns, the role of technology, and the ethics of integrating technology into mental healthcare can be found throughout the study. Market research was conducted to understand the industry in terms of the Porter’s Five Forces framework, recognizing low supplier power, a medium threat of new entry, and a high threat of substitution, competitive rivalry, and buyer power. A …
Effect Of Decorating Super Paramagnetic Iron Oxide Nanoparticles With Silver Nanoparticles On Their Magneto-Photo Thermal Heating Efficiency, Anthony Joseph Afful
Effect Of Decorating Super Paramagnetic Iron Oxide Nanoparticles With Silver Nanoparticles On Their Magneto-Photo Thermal Heating Efficiency, Anthony Joseph Afful
All Graduate Theses, Dissertations, and Other Capstone Projects
Cancer treatment is rather dangerous to the body, often involving many secondary effects, including nausea, hair loss, and weight fluctuations. The search for non-invasive, highly efficient, and targetable treatments ameliorates these issues. Super paramagnetic iron oxide nanoparticles (SPIONS) have been used for other medical purposes such as magnetic resonance imaging contrast agent and is being extensively studied as a potential candidate for many cancer therapeutic and diagnostic approaches due to its biocompatibility and superior magnetic properties. When subjected to an external alternating magnetic field SPIONS generate heat mainly due to the friction of the SPIONS against the fluid it is …
Campus Sexual Violence In The Time Of Covid-L9, Hannah Holt
Campus Sexual Violence In The Time Of Covid-L9, Hannah Holt
Master’s Theses
Campus sexual assault (CSA) was likely on the rise in the United States (Koss et al., 2022) even prior to the COVID-19 pandemic, during which there was a global increase in violence against women. The present study is a needed addition to the limited rigorous scientific studies on the impact of the COVID-19 pandemic on campus sexual assault (CSA). A mixed-methods, ecological, and critical feminist approach was used to investigate CSA during the mitigation period. The present study specifically utilized the Sexual Experiences Survey (Koss et al., 2007) to assess changes in frequency of victimization within two representative samples of …
Exploration Of Robotics Need In The Medical Field And Robotic Arm Operation Via Glove Control, Aditi Vijayvergia
Exploration Of Robotics Need In The Medical Field And Robotic Arm Operation Via Glove Control, Aditi Vijayvergia
Master’s Theses
This thesis project is an exercise in getting hands-on experience in redesigning and modifying a robotic system. It also involves understanding the current need for robotic applications in hospital settings. To achieve the above, a thorough literature review of the current state of robotics in a hospital setting was conducted. Moreover, a number of interviews with medical care professionals were completed. Three main themes were obtained from the literature review and five main themes were obtained from the interviews which will be presented in this thesis report. The next phase of the project involved redesigning a system that is composed …
Bibliography, Maire M. Blankenship
Bibliography, Maire M. Blankenship
Faculty/Staff Personal Papers
Bibliography of publications by Maire Blankenship.
A Biblioguidance Approach To Fostering Students’ Self-Efficacy To Advocate For Health, Jennifer R. Banas, Sara Gershon
A Biblioguidance Approach To Fostering Students’ Self-Efficacy To Advocate For Health, Jennifer R. Banas, Sara Gershon
Health Sciences and Physical Education Faculty Publications
Teaching the components of health advocacy is straightforward, but fostering young people’s self-efficacy to be health advocates for themselves, others, and their community is more complex. This complexity sometimes renders advocating for health, the basis of National Health Education Standard (NHES) #8, challenging to teach. We utilized a pedagogical approach called biblioguidance to teach this skill to 10th-grade students. The premise of biblioguidance, also called bibliotherapy, is that information, guidance, and even solace can be found through reading and vicariously living story events. To implement this approach, we consulted the literature and created a six-step framework to guide the design, …
Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica
Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica
Williams Honors College, Honors Research Projects
The use of electronic cigarettes, commonly referred to as e-cigarettes or vapes, has increased exponentially in recent years despite the lack of research into potentially negative physiological effects. The rise in e-cigarette use is likely due to the overwhelming evidence regarding the addictive properties of nicotine and the damage caused by traditional tobacco cigarettes. Most e-cigarettes, however, still contain nicotine and are associated with a rise in nicotine-related intoxications (Belkoniene et al., 2019). There are nicotine-free e-cigarette options, which are gaining popularity, but it is unknown if they carry similar or other negative physiological effects. Studies involving e-cigarettes containing nicotine …
The Effects Of Sex On Zebrafish Bone Metabolism, Simon Bagatto
The Effects Of Sex On Zebrafish Bone Metabolism, Simon Bagatto
Williams Honors College, Honors Research Projects
I investigated the effects of diet and sex on zebrafish bone metabolism. Zebrafish were subjected to either a high-calorie or low-calorie diet over a five-week period. After this diet, zebrafish scales were used to measure alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) enzyme activity with a fluorescent substrate. The enzyme activities were markers of the osteoblasts (ALP) and the osteoclasts (TRAP). These data were compared among sex and diet of the zebrafish using a repeated measures ANOVA statistical test. I also measured the number of resorption lacunae per scale (another indicator of osteoclast activity). The results showed higher TRAP …
Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell
Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell
Williams Honors College, Honors Research Projects
Damp granular media is a difficult environment to study because it is both practically complex and it lacks equations which fully describe its behavior. In this study, an oscillatory lateral head movement and its effects while penetrating damp granular media were tested using a robophysical model. This experimental research was inspired by the burrowing behavior of the clade Amphisbaenia, a group of usually limbless squamates that employ a variety of different burrowing behaviors, but it can apply to a wide range of burrowers. This research could help with both human burrowing technologies and the further investigation of animal behaviors.
Research News, Publications, 2023, Volume 2, Soumyajit Majumdar
Research News, Publications, 2023, Volume 2, Soumyajit Majumdar
Publications (2015-)
Publications that appeared during the period of April 1 through June 30, 2023
Research News, Publications, 2023, Volume 3, Soumyajit Majumdar
Research News, Publications, 2023, Volume 3, Soumyajit Majumdar
Publications (2015-)
Publications that appeared during the period of July 1 through September 30, 2023
Research News, Publications, 2023, Volume 4, Soumyajit Majumdar
Research News, Publications, 2023, Volume 4, Soumyajit Majumdar
Publications (2015-)
Publications that appeared during the period of October 1 through December 31, 2023
Research News, Grants, 2023, Volume 1, Soumyajit Majumdar
Research News, Grants, 2023, Volume 1, Soumyajit Majumdar
Grants (2015-)
Grants and contracts awarded during January - March 2023
Research News, Grants, 2023, Volume 2, Soumyajit Majumdar
Research News, Grants, 2023, Volume 2, Soumyajit Majumdar
Grants (2015-)
Grants and contracts awarded during April - June 2023
Research News, Grants, 2023, Volume 4, Soumyajit Majumdar
Research News, Grants, 2023, Volume 4, Soumyajit Majumdar
Grants (2015-)
Grants and contracts awarded during October - December 2023
The Effectiveness Of Treatments For Drug-Resistant Epilepsy: A Review Of Literature, Lauren Cummons
The Effectiveness Of Treatments For Drug-Resistant Epilepsy: A Review Of Literature, Lauren Cummons
Williams Honors College, Honors Research Projects
Many studies examine the treatment options for epilepsy; however, there is a lack of reviews compiling and evaluating the current treatments for drug-resistant epilepsy (DRE). This project aims to explore the existing body of research studies completed on treating DRE, evaluate the effectiveness of each treatment option, and assess what areas of research need more attention for future studies. Six primary DRE treatments from current research were thoroughly examined for this review. The quality of each treatment was evaluated based on the number of patients who had seizure freedom, had a seizure reduction, had adverse events, and had changes in …
Rim-To-Rim Wearables At The Canyon For Health (R2r Watch): Physiological, Cognitive, And Biological Markers Of Performance Decline In An Extreme Environment, Kristin Divis, Robert Abbott, Cathy Branda, Glory Emmanuel-Aviña, Jon Femling, J. Gabriel Huerta, Lucie Jelinková, J. Kyle Jennings, Emily A. Pearce, Daniel Ries, Danielle Sanchez, Austin Silva
Rim-To-Rim Wearables At The Canyon For Health (R2r Watch): Physiological, Cognitive, And Biological Markers Of Performance Decline In An Extreme Environment, Kristin Divis, Robert Abbott, Cathy Branda, Glory Emmanuel-Aviña, Jon Femling, J. Gabriel Huerta, Lucie Jelinková, J. Kyle Jennings, Emily A. Pearce, Daniel Ries, Danielle Sanchez, Austin Silva
Journal of Human Performance in Extreme Environments
Success in extreme environments comes with a cost of subtle performance decrements that if not mitigated properly can lead to lifethreatening consequences. Identification and prediction of performance decline could alleviate deleterious consequences and enhance success in challenging and high-risk operations. The Rim-to-Rim Wearables at the Canyon for Health (R2R WATCH) project was designed to examine the cognitive, physiological, and biological markers of performance decline in the extreme environment of the Grand Canyon Rim-to-Rim (R2R) hike. The study utilized commercial off-the-shelf cognitive and physiological monitoring techniques, along with subjective self-assessments and hematologic measurements to determine subject performance and changes across the …
Evaluation Of Selenomethionine Entrapped In Nanoparticles For Oral Supplementation Using In Vitro, Ex Vivo And In Vivo Models, Shane Forde, Giuliana Vozza, David J. Brayden, Jesus Maria Frias, Sinead M. Ryan
Evaluation Of Selenomethionine Entrapped In Nanoparticles For Oral Supplementation Using In Vitro, Ex Vivo And In Vivo Models, Shane Forde, Giuliana Vozza, David J. Brayden, Jesus Maria Frias, Sinead M. Ryan
Articles
Selenium methionine (Se Met) is an essential micronutrient required for normal body function and is associated with additional health benefits. However, oral administration of Se Met can be challenging due to its purported narrow therapeutic index, low oral bioavailability, and high susceptibility to oxidation. To address these issues, Se Met was entrapped in z e i n-coated nanoparticles made from chitosan using an ionic gelation formulation. The high stability of both the Se Met and s e l e n o methionine nanoparticles (Se Met-NPs) was established using cultured human intestinal and liver epithelial cells, rat liver homogenates, and rat …
Smoking Cessation Through Optimisation Of Clinical Care In Pregnancy: The Stop Randomised Controlled Trial, Brendan P. Mcdonnell, Patrick Dicker, Sheila Keogan, Luke Clancy, Carmen Regan
Smoking Cessation Through Optimisation Of Clinical Care In Pregnancy: The Stop Randomised Controlled Trial, Brendan P. Mcdonnell, Patrick Dicker, Sheila Keogan, Luke Clancy, Carmen Regan
Articles
This is a pragmatic randomised controlled trial of a dedicated smoking cessation clinic versus routine antenatal care as an intervention to reduce cigarette smoking behaviour. Smoking mothers randomised to the Smoking cessation Through Optimisation of clinical care in Pregnancy (STOP) clinic will have all antenatal care provided by a team comprising an obstetrician, a midwife, and a smoking cessation practitioner. This intervention includes ultrasound screening for fetal growth restriction. The control arm comprises two groups: one receiving standard care with ultrasound screening for fetal growth restriction, and one receiving standard care with ultrasound screening for growth restriction only if clinically …
The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo
The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo
Articles
The association between current smoking and coronavirus disease 2019 (COVID-19) progression remains uncertain. We aim to provide up-to-date evidence of the role of cigarette smoking in COVID-19 hospitalisation, severity and mortality. On 23 February 2022 we conducted an umbrella review and a traditional systematic review via PubMed/Medline and Web of Science. We used random-effects meta-analyses to derive pooled odds ratios of COVID-19 outcomes for smokers in cohorts of severe acute respiratory syndrome coronavirus 2 infected individuals or COVID-19 patients. We followed the Meta-analysis of Observational Studies in Epidemiology reporting guidelines. PROSPERO: CRD42020207003. 320 publications were included. The pooled odds ratio …