Medicine and Health Sciences Commons^™

Choose Well: Summary Of Mid-Point Evaluation Findings, Center For Applied Reasearch And Evaluation In Women's Health, East Tennessee State University

Center for Applied Research and Evaluation (CARE) in Women's Health Reports

This report summarizes key findings related to the evaluation of the Choose Well Initiative at the mid-point. Results are not complete but provide a brief summary of key findings and evidence to date.

Heparin Vs. Saline: Evaluating Evidence-Based Best Practice For Maintaining Patency Of Implanted Ports, Shannon D. Murdock

Master's Theses and Capstones

Background Implanted ports are frequently used for central venous access in the adult oncology population. Maintaining patency of these ports is important for continuing uninterrupted treatment and supportive care for oncologic patients. Historically, heparin solution has been used as a locking solution for implanted ports to prevent occlusion. However, evidence shows that 0.9% sodium chloride (normal saline or NS) as a lock solution is equally effective as heparin solution at maintaining implanted port patency and poses less risk to patients.

Local Problem In an ambulatory adult oncology clinic serving Seacoast New Hampshire, a gap was identified between clinical practice where …

Enhancing Education To Mitigate Workplace Violence To Increase Staff Safety In A High Acuity Setting: A Quality Improvement Project, Michelle Crowley

Master's Theses and Capstones

Background: The current microsystem is a critical access 8 bed Emergency Department with 3 hallway beds. On average it can see anywhere from 30-50 patients in a 24 hour period. Due to the nature of the microsystem, staff are at high risk for experiencing workplace violence (WPV). Within this microsystem staff do not have a readily available communication device on their person in case of an adverse event leaving them susceptible to patient to staff WPV. Staff within this microsystem are Management of Aggressive Behavior (MOAB) 1 and 2 trained, however this does not provide education on risk factors for …

Incorporating Non-Pharmacological Labor Coping Methods To Improve Nursing Care And Reduce Primary Cesarean Section Rates: A Quality Improvement Project, Cait Maccabe

Master's Theses and Capstones

Abstract

BACKGROUND: Cesarean sections (c-sections), while life-saving in some circumstances, carry a significantly higher risk of morbidity and mortality than vaginal birth for birthing patients and neonates alike. Despite this, rates of c-section have continued to rise in the US and around the world. As primary cesarean births are highly likely to lead to repeat cesarean births, concerted efforts are being made to reduce them both broadly and within the setting of this quality improvement (QI) project: a labor and delivery unit located within a Level II trauma center in New Hampshire. A literature review provided evidence supporting the use …

Dietary Whey Protein Increases Brain Leukocytes In Mice Regardless Of Their Hypersensitivity Status, Dilini Ekanayake

Biomedical Sciences Posters and Presentations

Cow’s milk allergy (CMA) often manifests as milder reactions and may be linked to neurological problems. Previously, we demonstrated that C57BL/6J mice sensitized to a bovine whey allergen, β-lactoglobulin (BLG, Bos d 5), moderately increased BLG-specific IgE levels and exhibited behavioral changes without severe allergic reactions. When these non-anaphylactic CMA mice were placed on a whey-protein (WP)-containing diet for 2 weeks to simulate continuous dairy consumption, we found neuropathology indicative of neuroinflammation and cortical demyelination. Since immune cells migrate to the central nervous system (CNS) and promote neuroinflammation in demyelinating conditions such as multiple sclerosis, we hypothesized that the number …

Investigating The Potential Role Of Akkermansia Muciniphila Supplementation In Neuroinflammation: A Progress Report, Geetika Verma

Biomedical Sciences Posters and Presentations

Gut bacteria are important for proper development and function of the host immune system (1). Recent studies have provided association of altered microbiome in both food allergy and neuropsychiatric disorders (2, 3) indicating potential role of microbiome in regulating Gut-Brain-Axis. Akkermansia muciniphila belongs to the phylum Verrucomicrobia, is a commensal mucin degrading bacterial species (4). A. muciniphila protects the gut barrier by facilitating host mucus production. Since patients with food allergy have increased gut permeability, protection of intestinal barrier by increased mucus production may be beneficial in preventing allergen and pathogen infiltrations, hence, minimizing inflammation. A. muciniphila is well known …

Effectiveness Of Occupational Therapy’S Role In Promotion Of Role Fulfillment With Aviation Students In Higher Education Who Are Experiencing Mental Health Conditions, Payton O. Schilke, Olivia G. Schoffstall, Lexi K. Smith, Gracie J. Stimac

Critically Appraised Topics

This critically appraised topic paper focuses on occupational therapy’s role and the interventions for improving the mental health of aviation students in higher education. Aviation students are higher education student pilots learning to become pilots within various roles. Stress and fatigue among students in higher education are prominent problems (Beiter, 2015; Kalmakis et al., 2021). The focus on aviation students for this critically appraised topic paper reveals the unique stressors relating to flight training that is added on top of the normal academic stress load that university students face (Robertson & Ruiz, 2010). Due to these stress factors, the mental …

The Role Of Occupational Therapists Working With Adolescents With Mental Health Conditions In The Juvenile Justice System, Angelina M. Caron, Madalyn M. England, Mattea J. Johnson

Critically Appraised Topics

This critically appraised topic paper focuses on interventions for improving adolescents' mental health status to promote engagement in occupations in the JJS. With many factors to consider, adolescent demographics and previous contexts were described first, then the impact that mental health programs in the JJS have on adolescents' mental health was reviewed. Finally, occupational therapy’s role in improving occupational engagement through addressing mental health was investigated.

Dietary Nitrate Supplementation Enhances Performance And Speeds Muscle Deoxyhaemoglobin Kinetics During An End-Sprint After Prolonged Moderate-Intensity Exercise, Samantha N. Rowland, Mariasole Da Boit, Rachel Tan, George P. Robinson, Emma O’Donnell, Lewis J. James, Stephen J. Bailey

All Faculty Open Access Publications

Short-term dietary nitrate (NO3−) supplementation has the potential to enhance performance during submaximal endurance, and short-duration, maximal-intensity exercise. However, it has yet to be determined whether NO3− supplementation before and during submaximal endurance exercise can improve performance during a short-duration, maximal-intensity end-sprint. In a randomised, double-blind, crossover study, 9 recreationally active men ingested NO3−-rich (BR: 8 mmol NO3−/day) and NO3−-depleted (PL: 0.75 mmol NO3−/day) beetroot powder for 7 days. On day 7, participants completed 2 h of moderate-intensity cycling, which immediately transitioned into a 60 s maximal-intensity end-sprint, with supplements ingested 2 h before and 1 h into the moderate-intensity …

Exploring Breast Tissue Microbial Composition And The Association With Breast Cancer Risk Factors, Rana German, Natascia Marino, Chris Hemmerich, Ram Podicheti, Douglas B. Rusch, Leah T. Stiemsma, Hongyu Gao, Xiaoling Xuei, Pam Rockey, Anna Maria Storniolo

All Faculty Open Access Publications

Background: Microbial dysbiosis has emerged as an important element in the development and progression of various cancers, including breast cancer. However, the microbial composition of the breast from healthy individuals, even relative to risk of developing breast cancer, remains unclear. Here, we performed a comprehensive analysis of the microbiota of the normal breast tissue, which was analyzed in relation to the microbial composition of the tumor and adjacent normal tissue. Methods: The study cohorts included 403 cancer-free women (who donated normal breast tissue cores) and 76 breast cancer patients (who donated tumor and/or adjacent normal tissue samples). Microbiome profiling was …

The Mutational Landscape In Chronic Myelomonocytic Leukemia And Its Impact On Allogeneic Hematopoietic Cell Transplantation Outcomes: A Center For Blood And Marrow Transplantation Research (Cibmtr) Analysis, Matthew Mei, Raju Pillai, Soyoung Kim, Noel Estrada-Merly, Michelle Afkhami, Lixin Yang, Zhuo Meng, Muhammad Bilal Abid, Mahmoud Aljurf, Ulrike Bacher, Amer Beitinjaneh, Christopher Bredeson, Jean-Yves Cahn, Jan Cerny, Edward Copelan, Corey Cutler, Zachariah Defilipp, Miguel Angel Diaz Perez, Nosha Farhadfar, César O Freytes, Shahinaz M Gadalla, Siddhartha Ganguly, Robert Peter Gale, Usama Gergis, Michael R Grunwald, Betty K Hamilton, Shahrukh Hashmi, Gerhard C Hildebrandt, Hillard M Lazarus, Mark Litzow, Reinhold Munker, Hemant S Murthy, Sunita Nathan, Taiga Nishihori, Sagar S Patel, David Rizzieri, Sachiko Seo, Mithun Vinod Shah, Melhem Solh, Leo F Verdonck, Ravi Vij, Ronald M Sobecks, Betul Oran, Bart L Scott, Wael Saber, Ryotaro Nakamura

Department of Medical Oncology Faculty Papers

Somatic mutations are recognized as an important prognostic factor in chronic myelomonocytic leukemia (CMML). However, limited data are available regarding their impact on outcomes after allogeneic hematopoietic cell transplantation (HCT). In this registry analysis conducted in collaboration with the Center for International Blood and Marrow Transplantation Registry database/sample repository, we identified 313 adult patients with CMML (median age: 64 years, range, 28- 77) who underwent allogeneic HCT during 2001-2017 and had an available biospecimen in the form of a peripheral blood sample obtained prior to the start of conditioning. In multivariate analysis, a CMML-specific prognostic scoring system (CPSS) score of …

Inequitable By Design: The Patent Culture, Law, And Politics Behind Covid-19 Vaccine Global Access, Ximena Benavides

University of Michigan Journal of Law Reform

COVID-19 vaccine access has been highly inequitable worldwide, with coverage depending largely on a country’s wealth. By the end of 2021, 64.1% of people living in high-income countries had received at least one dose of the vaccine, compared to only 5.4% of those in low-income countries. Similarly, only high- and upper-middle-income countries had received the most effective vaccines.

The uneven distribution of these lifesaving vaccines is made complex due to the convergence of several factors, but it suggests that the extraordinary expanding and ossifying market and political power of a few vaccine manufacturers founded on intellectual property and complementary policies …

Policies For Expanding Hepatitis C Testing And Treatment In United States Prisons And Jails, Tessa Bialek, Dr. Matthew J. Akiyama M.D.

University of Michigan Journal of Law Reform

Hepatitis C virus (HCV) is highly prevalent in United States prisons and jails. In prisons and jails, rates of infection are ten to twenty times greater than national levels. And, more than thirty percent of all people living with HCV in the United States will spend time in prisons and jails in any given year. Rates are especially high among people who inject drugs (PWID), a population whose members are also likely to move between carceral settings and the community. Thus, addressing HCV among incarcerated populations would have a significant effect on the virus’s transmission both in and out of …

Dermatoses Of The Breast During Lactation, Divya Shan, Sindhuja Koppu, Valerie Coleman, Gauri Gulati, Kimberly Salkey

Open and Affordable Course Content at VCU

No abstract provided.

Dermatologic Manifestations Of Rheumatic Disease: Malignant Cutaneous Tumors, Divya Shan, Julianna S. Kang, Allison Cinats, Julia R. Nunley, Beth Rubinstein

Open and Affordable Course Content at VCU

No abstract provided.

Clay Use As Mindfulness For Women In Early Substance Use Recovery, Cheryl Feldman

Art Therapy | Doctoral Dissertations

Substance Use Disorders (SUDs) are an epidemic in the United States comprising 4.4 million women, including high rates of recidivism, and often accompanied by comorbid mental health issues. Recognizing the need for effective tools to support women in recovery, this research aligns the key tenets of present focus and personal control within Alcoholics Anonymous (AA) with various established mindfulness-based therapies, while using a Positive Psychology framework to conceptualize strategies to help enhance mindfulness in women in early recovery. Although engaging in clay work has been linked to mindfulness for its capacity to foster a state of presence and self-centering, scant …

Implementing Trauma-Informed Care Across All Occupational Therapy Settings, Scout Hutchinson, Kristin Domville, Pam Kasyan-Howe

Fall 2023 Virtual OTD Capstone Symposium

A quantitative research design was utilized to analyze the effectiveness of an educational seminar on trauma- informed disseminated to occupational therapy practitioners, determining their previous knowledge on trauma-informed care. The research conducted has provided a more comprehensive understanding of this population and where services are needed. There is still much work to be done with this topic and the cultural shift towards providing trauma sensitive resources to occupational therapy practitioners. The future of trauma-informed care being incorporated into occupational therapy practice settings is up to the motivation and heart of future occupational therapists in hopes to strengthen the resources offered …

Associations Of Stress, Health Behaviors, And Obesity Among African American Immigrants, Wole David Akinsola

Walden Dissertations and Doctoral Studies

AbstractObesity has been identified as a predisposing factor that poses a serious threat for the development of chronic diseases and contributes to health disparities affecting both minority and vulnerable populations. Though previous studies reported the association of stress with health status and behavior, there is little or no research on the heterogeneity of obesity predictors in specific minority populations in the United States. The purpose of this study was to examine the predictors of obesity among adult African American immigrant populations in the United States. Studying obesity in this population may help policymakers tailor interventions that could reduce obesity prevalence. …

Abortion Decisions As Humanizing Acts: The Application Of Ambivalent Sexism And Objectification To Women-Centered Anti-Abortion Rhetoric, Rachel L. Dyer, Olivia R. Checkalski, Sarah Gervais

Department of Psychology: Faculty Publications

Women-centered anti-abortion rhetoric, grounded in ostensibly positive beliefs that pregnant people are precious objects who must be protected from having abortions, has proliferated anti-abortion activism and legislation. However, abortion stigma, marked by negative perceptions of people who terminate pregnancies, is the most widely used theoretical tool for understanding the social and psychological implications of abortion. In this article, we first integrate these two seemingly contradictory perspectives on abortion through the lens of ambivalent sexism theory. We then argue that ambivalent sexism paves the way for objectifying perceptions and treatment of pregnant people; specifically, our typology of reproductive objectification provides a …

Associations Between Socioecological Factors And Breastfeeding Duration Among Obese Mothers In Mississippi, Maria Mercedes Miranda Porter

Walden Dissertations and Doctoral Studies

There is a growing obesity pandemic in the United States. Low breastfeeding duration rates and socioecological factors lead to obesity in the most southern states. Overweight and obese breastfeeding mothers have not been primarily studied. There is mixed information regarding duration of breastfeeding, BMI, and heart health, as well as a lack of quantitative analyses involving reducing obesity rates in mother-child dyads. The purpose of this quantitative cross-sectional study was to investigate whether there were any associations between breastfeeding duration and BMI, heart health problems, breastfeeding support, and eating and exercise among Mississippi overweight and obese postpartum women based on …

Fall Prevention On The In-Patient Neurological Stroke Unit, Syvol Letwan Middleton

Walden Dissertations and Doctoral Studies

AbstractThe purpose of this quality improvement (QI) evaluation project was to decrease patient falls on a neurological stroke unit. This unit had the most falls throughout the hospital system. The unit averaged 50-60 falls per year with an average of 4.75 falls per month. Guided by Neumann’s system model, the project targeted those patients at the highest risk for falling related to deficits post-stroke and post-neurological disease process. Staff were informed about Last fall, Express needs, Awareness of safety, and Frequency of bowel and bladder (LEAF) to determine if this tool could decrease falls in the neurological stroke population patients. …

A National Assessment Of Household, Community, And Environmental Situations On Breastfeeding Decisions, Marnita Siglar Thomas

Walden Dissertations and Doctoral Studies

Exclusively breastfeeding has been proven to be an effective preventive measure for childhood obesity; however, breastfeeding practices decline after 6 months. Secondary data from the 2018-2019 combined National Survey of Children's Health were used for this study to determine the household, community, and physical environment relationship between individuals' decisions to breastfeed and sustainment in the United States (N=16,750). Grounded by the theoretical framework of the socio-ecological model, the results suggested that household, community, and physical environments predict individuals' decisions to initiate breastfeeding and sustainment nationally (p < 0.001). Binary logistic regression, controlling for maternal age, indicated a statistical significance between breastfeeding initiation and income (p = 0.043, p = 0.041), family structure (p = 0.003, p < 0.001), education (p < 0.001, p < 0.001, p < 0.001), neighborhood support (p < 0.001), and neighborhood amenities (p = 0.039, p <0.001, p < 0.001). A statistical significance between breastfeeding duration and family structure (p = 0.061), education (p < 0.001, p < 0.001), maternal overall health (p <0.001), neighborhood support (p = 0.008), neighborhood safety (p = 0.006), and neighborhood amenities (p = 0.019) was found when controlling for maternal age. Implications for positive social change include providing health professionals with knowledge on breastfeeding decision making to encourage new recommendations and implement new practices and policies to promote breastfeeding and ultimately reduce the incidence of overweight and obesity in children nationwide.

Straight From The Coyote’S Mouth: Genetic Identification Of Prey Through Oral Swabs Of Predators, Julie K. Young, Amanda M. Mast, James A. Walton, Torrey Rodgers, Antionette J. Piaggio, Daniel R. Taylor, Karen E. Mock

United States Department of Agriculture Wildlife Services: Staff Publications

Human-carnivore conflicts often involve the depredation of domestic livestock. These depredation events are rarely observed, yet mitigation typically involves identifying the species or individual involved for removal or relocation. We tested a molecular method to identify individuals involved in depredation events using mouth swabs to determine if prey DNA could be detected, and for how long. We fed mule deer Odocoileus hemionus meat to captive coyotes Canis latrans and swabbed their mouths at five predetermined intervals between 2–72 h after consumption of the deer meat. We assessed two different molecular forensic methods to analyze the saliva swabs: qPCR for species …

Implementation Of Night Shift Rounding To Improve Nursing Communication And Reduce Days Of Intubation In The Intensive Care Setting, Lisa Wilkinson

Walden Dissertations and Doctoral Studies

Multidisciplinary rounds are the gathering of various health care providers who have a shared interest in a patient’s well-being to discuss the plan of care and the patient’s progress through their hospital stay. This multidisciplinary group of staff can be the providers, the nurse, charge nurse, social worker, pharmacist, dietician, respiratory, chaplaincy, and occupational and physical therapists. On night shift at the project site, this rounding process did not occur, leaving the staff feeling they were not involved in the plan of care. The purpose of this quality improvement evidenced-based project was to create a process change, introduced to the …

Educating Nurses On Failure To Rescue Due To Treatment Delay, Ganiyu Olasheni Adewale

Walden Dissertations and Doctoral Studies

Studies have found a shortfall in nurses' skills in caring for patients with a significant risk of failure to rescue in an acute care setting. The practice gap the healthcare facility was experiencing today was a gap in relation to failure to rescue with an increased rate of sentinel cases. There was a knowledge deficit among critical care nurses. The importance of educating nursing staff is to increase their knowledge and help decrease the occurrence of failure to rescue in an acute care setting. The practice-focused question for this education project asked if educating nursing staff with a medical-surgical competency …

Implementation Of A Staff Education Project On Human Trafficking For Emergency Department Staff, Monica Rena Hunt

Walden Dissertations and Doctoral Studies

Evidence demonstrates that people who are being trafficked will seek medical attention, especially in emergency departments, which presents a rare opportunity to identify and support them. This Doctor of Nursing Project (DNP) was designed to evaluate if educating emergency department nurses on using an adult screening tool for human trafficking improves knowledge in a local emergency department in Texas. The participants were 11 registered nurses. The Maslow hierarchy of needs theory and the adult learning theory were used as a framework, and the models used to construct the educational project were Gagne’s nine levels of learning and the use of …

Staff Education For Nurses And Providers On Rapid Mood Screener, Lolade Adekemi Ogunleye

Walden Dissertations and Doctoral Studies

Advances in the psychiatric field have led to the development of valuable tools that can be used in screening patients to understand their condition better. Indeed, instruments such as the Rapid Mood Screener (RMS) have been significantly used to help diagnose conditions such as bipolar disorder. The implication is that such tools need to be appropriately used by health care practitioners such as nurses for better and more accurate diagnostic results. A more accurate diagnosis is a foundation for better patient management and outcomes. Therefore, as part of a bigger plan, mental health facilities should make deliberate efforts to ensure …

Help-Seeking Behaviors And Employment Hope Among Depressed Black Male Foster Care Alumni, Vanessa Jennings

Walden Dissertations and Doctoral Studies

Traumatic depression is a system of experiences where the mind, heart, and gut track happenings lingering among systemic models of prevention and intervention and personal stories. This nonexperimental correlational study aimed to provide insights into mental help-seeking and employment hope among depressed Black/African American foster care male alums. The central research question was to what degree, if any, a positive relationship exists between employment hope and seeking access to mental health-related services among male foster care alums who identify with depression. It was hypothesized that a statistically significant relationship exists. The social cognitive career theory and theory of planned behavior …

Movements And Resource Selection Of Wild Pigs Associated With Growth Stages Of Corn, Bethany A. Friesenhahn, Randall W. Deyoung, Michael J. Cherry, Humberto L. Perotto-Baldivieso, Kurt C. Vercauteren, Nathan P. Snow

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) are one of the most successful invasive species globally and are often implicated in agricultural damage. This damage is expected to increase as ranges of wild pigs expand, impacting the human food supply and increasing costs of food production. Our objective was to evaluate movement behaviors of wild pigs relative to resource availability and landscape features in an agriculture-dominated landscape, with a goal of informing management practices for reducing damage to corn. We monitored hourly movements of adult wild pigs relative to corn crops using GPS collars during the 2019 and 2020 growing seasons (Feb–Sept) in …

Burmese Pythons In Florida: A Synthesis Of Biology, Impacts, And Management Tools, Jacquelyn C. Guzy, Bryan G. Falk, Brian J. Smith, John David Willson, Robert N. Reed, Nicholas G. Aumen, Michael L. Avery, Ian A. Bartoszek, Earl Campbell, Michael S. Cherkiss, Natalie M. Claunch, Andrea F. Currylow, Tylan Dean, Jeremy Dixon, Richard Engeman, Sarah Funck, Rebekah Gibble, Kodiak C. Hengstebeck, John S. Humphrey, Margaret E. Hunter, Jillian M. Josimovich, Jennifer Ketterlin, Michael Kirkland, Frank J. Mazzotti, Robert Mccleery, Melissa A. Miller, Matthew Mccollister, M. Rockwell Parker, Shannon E. Pittman, Michael Rochford, Christina Romagosa, Art Roybal, Ray W. Snow, Mckayla M. Spencer, J. Hardin Waddle, Any A. Yackel Adams, Kristen M. Hart

United States Department of Agriculture Wildlife Services: Staff Publications

Burmese pythons (Python molurus bivittatus) are native to southeastern Asia, however, there is an established invasive population inhabiting much of southern Florida throughout the Greater Everglades Ecosystem. Pythons have severely impacted native species and ecosystems in Florida and represent one of the most intractable invasive-species management issues across the globe. The difficulty stems from a unique combination of inaccessible habitat and the cryptic and resilient nature of pythons that thrive in the subtropical environment of southern Florida, rendering them extremely challenging to detect. Here we provide a comprehensive review and synthesis of the science relevant to managing invasive …