Medicine and Health Sciences Commons^™

Tele-Mental Health Services: Addressing Healthcare Needs For Rural Population, Foram Patel, Samuel T. Opoku

Eagles Talking About the Public’s Health

No abstract provided.

A Refreshing Change: Safeguarding Mothers And Children From Pfas Exposure, Emmanuela Nwaonumah, Alisha Riggins, Emmanuel Azu, Oluwatoyin Ayo-Farai, Joanne Chopak-Foss, Logan Cowan, Atin Adhikari

Eagles Talking About the Public’s Health

No abstract provided.

A Breakthrough In Accessibility: Over-The-Counter Oral Contraceptives, Alisha Riggins, Emmanuela Nwaonumah, Tobi Oloyede, Joanne Chopak-Foss, Logan Cowan, Elizabeth Olayinka

Eagles Talking About the Public’s Health

No abstract provided.

Improving Cervical Cancer Screening In Sub-Saharan Africa, Nigeria: Reaching Levels Of Cervical Cancer Prevention In Developed Countries, Chigozie Alexandra Ogwara, Biyi-Olutunde Olusegun, Yelena Tarasenko

Eagles Talking About the Public’s Health

No abstract provided.

Heavy Metals In Baby Food: It’S Time For Public Health Researchers To Wake Up, Sarah Sejoro, Atin Adhikari

Eagles Talking About the Public’s Health

No abstract provided.

Summary Of Gynaecological Cancer Among Aboriginal And/Or Torres Strait Islander People In Australia, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

This publication, in plain language, is based on information presented in the Review of gynaecological cancer among Aboriginal and/or Torres Strait Islander people in Australia (2023). This short, visual report summarises the key findings and concepts from the review to provide a holistic picture of gynaecological cancer among Aboriginal and/or Torres Strait Islander women. It is a quick source of information covering:

• the social, cultural and historical contexts that contribute to inequitable gynaecological cancer rates among Aboriginal and/or Torres Strait Islander women
• the extent of gynaecological cancer, specifically cervical cancer, ovarian cancer and uterine cancer, including the incidence, mortality, …

Association Between Micronutrients, Oxidative Stress Biomarkers And Angiogenic Growth Mediators In Early And Late-Onset Preeclamptic Ghanaian Women, Enoch O. Anto, Wina I. O. Boadu, Otchere Addai-Mensah, Yaw A. Wiafe, William K. B. A. Owiredu, Christian Obirikorang, Max E. Annani-Akollor, Eric Adua, Michael Appiah, Stephen Opoku, Emmanuel Acheampong, Evans A. Asamoah, Eddie W. Owiredu, Agartha O. Anto, Augustine Tawiah, Frank Ankobea, Ebenezer Afrifa Yamoah, David A. Coall

Research outputs 2022 to 2026

Objectives: Micronutrients, especially calcium (Ca) and magnesium (Mg) are reported to reduce preeclampsia events via several factors such as endothelial cell control, optimal oxidative stress and a balanced angiogenic growth mediator. We evaluated the association of micronutrients with oxidative stress biomarkers, and angiogenic growth mediators in early-onset preeclampsia and late-onset preeclampsia. Methods: This case-control study recruited 197 preeclampsia (early-onset preeclampsia = 70 and late-onset preeclampsia = 127) as cases and 301 normotensive pregnant women as controls from the Komfo Anokye Teaching Hospital, Ghana. Samples were collected after 20 weeks of gestation for both cases and controls and estimated for Ca, …

Cancer Survivor Preferences For Models Of Breast Cancer Follow-Up Care: Selecting Attributes For Inclusion In A Discrete Choice Experiment, Sanjeewa Kularatna, Michelle Allen, Ruvini M. Hettiarachchi, Fiona Crawford-Williams, Sameera Senanayake, David Brain, Nicolas H. Hart, Bogda Koczwara, Carolyn Ee, Raymond J. Chan

Research outputs 2022 to 2026

Background and Objective: It is critical to evaluate cancer survivors’ preferences when developing follow-up care models to better address the needs of cancer survivors. This study was conducted to understand the key attributes of breast cancer follow-up care for use in a future discrete choice experiment (DCE) survey. Methods: Key attributes of breast cancer follow-up care models were generated using a multi-stage, mixed-methods approach. Focus group discussions were conducted with cancer survivors and clinicians to generate a range of attributes of current and ideal follow-up care. These attributes were then prioritised using an online survey with survivors and healthcare providers. …

Ctla4 Mrna Is Downregulated By Mir-155 In Regulatory T Cells, And Reduced Blood Ctla4 Levels Are Associated With Poor Prognosis In Metastatic Melanoma Patients, Prasanna Kumar Vaddi, Douglas Grant Osborne, Andrew Nicklawsky, Nazanin K. Williams, Dinoop Ravindran Menon, Derek Smith, Jonathan Mayer, Anna Reid, Joanne Domenico, Giang Huong Nguyen, William A. Robinson, Melanie Ziman, Dexiang Gao, Zili Zhai, Mayumi Fujita

Research outputs 2022 to 2026

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint expressed in regulatory T (Treg) cells and activated T lymphocytes. Despite its potential as a treatment strategy for melanoma, CTLA-4 inhibition has limited efficacy. Using data from The Cancer Genome Atlas (TCGA) melanoma database and another dataset, we found that decreased CTLA4 mRNA was associated with a poorer prognosis in metastatic melanoma. To investigate further, we measured blood CTLA4 mRNA in 273 whole-blood samples from an Australian cohort and found that it was lower in metastatic melanoma than in healthy controls and associated with worse patient survival. We confirmed these findings …

Feasibility Meets Implementation Science: Narrowing The Research-To-Practice Gap For Exercise Activity In Multiple Sclerosis, James Smith, Onno Van Der Groen, Yvonne Learmonth

Research outputs 2022 to 2026

Background: There is a need to identify why multiple sclerosis exercise research is not translating into real-world participation. To lay the foundations of strong clinical research, considering the translational element of implementation science at the feasibility phase of a trial is vital. Methods: Document analysis was used to examine document sources on exercise activity interventions designed for people living with multiple sclerosis. Document sources focused on multiple sclerosis research that incorporated exercise prescription elements and behaviour change and were feasibility studies incorporating aspects of implementation science. Results: Implementation science should come much earlier than the efficacy or effectiveness research pipeline. …

Gender As A Moderator Of Spirituality And Spiritual Care In Icu Nurses During Covid-19 Pandemic, Ruqayya S. Zeilani, Ahmad M.R. Al-Qunneh, Diana H. Arabiat, Ayman Hamdan-Mansour

Research outputs 2022 to 2026

Background: Earlier research has found that female healthcare providers often report greater spirituality and spiritual care than males. This would evoke attention toward factors contributing to such differences, particularly gender. Aim: To examine the moderating effects of gender on the relationships between demographic characteristics of ICU nurses and their perceived spirituality and spiritual care. Methods: A cross-sectional correlational design was used to recruit a national sample of 865 nurses working in ICUs in Jordan and providing care to patients diagnosed with COVID-19. Data were collected using a self-report bilingual version of Spirituality and Spiritual Care Rating Scale (SSC) and analysed …

“They Are Dealing With People’S Lives…”: Diagnostic And Post-Diagnostic Healthcare Experiences In Primary Progressive Aphasia, Tisha Ho, Anne Whitworth, Deborah Hersh, Jade Cartwright

Research outputs 2022 to 2026

Purpose: The healthcare experience is a multifaceted and varied process, particularly for people living with complex conditions such as primary progressive aphasia (PPA). Different experiences influence pathways through the health system, impacting client outcomes. To our knowledge, no previous studies have directly explored the healthcare experiences of people with PPA and their families. This study aimed to explore the experiences of people living with PPA from the perspective of both the person with PPA and their families during diagnostic and post-diagnostic phases, and to identify factors influencing service access and perceptions of quality of care. Method: The study followed an …

A Comprehensive Examination Of The Evidence For Whole Of Diet Patterns In Parkinson's Disease: A Scoping Review, Joanna Rees, Jillian Ryan, Manja Laws, Amanda Devine

Research outputs 2022 to 2026

Both motor and non-motor symptoms of Parkinson’s disease (PD), a progressive neurological condition, have broad-ranging impacts on nutritional intake and dietary behaviour. Historically studies focused on individual dietary components, but evidence demonstrating ameliorative outcomes with whole-of-diet patterns such as Mediterranean and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) is emerging. These diets provide plenty of antioxidant rich fruits, vegetables, nuts, wholegrains and healthy fats. Paradoxically, the ketogenic diet, high fat and very low carbohydrate, is also proving to be beneficial. Within the PD community, it is well advertised that nutritional intake is associated with disease progression and symptom severity but understandably, …

Covid-19 In Western Australia: ‘The Last Straw’ And Hopes For A ‘New Normal’ For Parents Of Children With Long-Term Conditions, Stephanie Smith, Mary Tallon, James Smith, Lauren Jones, Evalotte Mörelius

Research outputs 2022 to 2026

Background: Children with long-term conditions are vulnerable due to the treatments required for their conditions. Since the start of the coronavirus disease 2019 (COVID-19) pandemic, Western Australians experienced restrictions that changed daily life activities but were able to return to some of their previous routines due to the restrictions. Aim: The study explored the stress experiences of parents caring for children with long-term conditions during COVID-19 in Western Australia. Design and Participants: The study was codesigned with a parent representative caring for children with long-term conditions to ensure essential questions were targeted. Twelve parents of children with various long-term conditions …

Effects Of Submaximal And Supramaximal Accentuated Eccentric Loading On Mass And Function, Sergio Maroto-Izquierdo, Fernando Martín-Rivera, Kazunori Nosaka, Marco Beato, Javier González-Gallego, José A. De Paz

Research outputs 2022 to 2026

Introduction: Eccentric-overload (EO) resistance training emerges as an alternative to more optimally prescribe intensity relative to the force generation capabilities of the eccentric muscle contraction. Given the difficulties to individually prescribe absolute eccentric loads relative to each person’s eccentric ability, setting the load relative to the concentric one-repetition maximum (1-RM) is the most used EO training approach. Therefore, we investigated the effects of submaximal and supramaximal (i.e., eccentric loads above 100% of 1-RM) accentuated eccentric training on changes in lean mass, anabolic hormonal responses and muscle function. Methods: Physically active university students (n = 27) were randomly assigned to two …

Female Athlete Health Domains: A Supplement To The International Olympic Committee Consensus Statement On Methods For Recording And Reporting Epidemiological Data On Injury And Illness In Sport, Isabel S. Moore, Kay M. Crossley, Kari Bo, Margo Mountjoy, Kathryn E. Ackerman, Juliana D. S. Antero, Jorunn S. Borgen, Wendy J. Brown, Caroline S. Bolling, Benjamin Clarsen, Wayne Derman, Paul Dijkstra, Amber Donaldson, Kirsty J. Elliott-Sale, Carolyn A. Emery, Lene Haakstad, Astrid Junge, Nonhlanhla S. Mkumbuzi, Sophia Nimphius, Debbie Palmer, Mireille Van Poppel, Jane S. Thornton, Rita Tomás, Phathokuhle C. Zondi, Evert Verhagen

Research outputs 2022 to 2026

The IOC made recommendations for recording and reporting epidemiological data on injuries and illness in sports in 2020, but with little, if any, focus on female athletes. Therefore, the aims of this supplement to the IOC consensus statement are to (i) propose a taxonomy for categorisation of female athlete health problems across the lifespan; (ii) make recommendations for data capture to inform consistent recording and reporting of symptoms, injuries, illnesses and other health outcomes in sports injury epidemiology and (iii) make recommendations for specifications when applying the Strengthening the Reporting of Observational Studies in Epidemiology-Sport Injury and Illness Surveillance (STROBE-SIIS) …

Lepidium Meyenii Walp (Maca)-Derived Extracellular Vesicles Ameliorate Depression By Promoting 5-Ht Synthesis Via The Modulation Of Gut–Brain Axis, Rui Hong, Lan Luo, Liang Wang, Zhao-Li Hu, Qi-Rong Yin, Ming Li, Bin Gu, Bin Wang, Tao Zhuang, Xin-Yue Zhang, Yuan Zhou, Wan Wang, Lin-Yan Huang, Bing Gu, Su-Hua Qi

Research outputs 2022 to 2026

Depression is a common and debilitating condition for which effective treatments are needed. Lepidium meyenii Walp (Maca) is a plant with potential medicinal effects in treating depression. Recently, there has been growing interest in plant-derived extracellular vesicles (EVs) due to their low toxicity and ability to transport to human cells. Targeting the gut–brain axis, a novel strategy for depression management, may be achieved through the use of Maca-derived EVs (Maca-EVs). In this study, we successfully isolated Maca-EVs using gradient ultracentrifugation and characterized their shape, size, and markers (CD63 and TSG101). The in vivo imaging showed that the Dil-labeled Maca-EVs crossed …

Location Of Pathogenic Variants In Psen1 Impacts Progression Of Cognitive, Clinical, And Neurodegenerative Measures In Autosomal-Dominant Alzheimer's Disease, Stephanie A. Schultz, Zahra Shirzadi, Aaron P. Schultz, Lei Liu, Colleen D. Fitzpatrick, Eric Mcdade, Nicolas R. Barthelemy, Alan Renton, Bianca Esposito, Nelly Joseph-Mathurin, Carlos Cruchaga, Charles D. Chen, Alison Goate, Ricardo F. Allegri, Tammie L. S. Benzinger, Sarah Berman, Helena C. Chui, Anne M. Fagan, Martin R. Farlow, Nick C. Fox, Brian A. Gordon, Gregory S. Day, Neill R. Graff-Radford, Jason J. Hassenstab, Bernard J. Hanseeuw, Anna Hofmann, Clifford R. Jack Jr, Mathias Jucker, Celeste M. Karch, Robert A. Koeppe, Jae-Hong Lee, Allan I. Levey, Johannes Levin, Ralph Martins, Hiroshi Mori, John C. Morris, James Noble, Richard J. Perrin, Pedro Rosa-Neto, Stephen P. Salloway, Raquel Sanchez-Valle, Peter R. Schofield, Chengjie Xiong, Keith A. Johnson, Randall J. Bateman, Reisa A. Sperling, Jasmeer P. Chhatwal, Dominantly Inherited Alzheimer Network Investigators

Research outputs 2022 to 2026

Although pathogenic variants in PSEN1 leading to autosomal-dominant Alzheimer disease (ADAD) are highly penetrant, substantial interindividual variability in the rates of cognitive decline and biomarker change are observed in ADAD. We hypothesized that this interindividual variability may be associated with the location of the pathogenic variant within PSEN1. PSEN1 pathogenic variant carriers participating in the Dominantly Inherited Alzheimer Network (DIAN) observational study were grouped based on whether the underlying variant affects a transmembrane (TM) or cytoplasmic (CY) protein domain within PSEN1. CY and TM carriers and variant non-carriers (NC) who completed clinical evaluation, multimodal neuroimaging, and lumbar puncture for collection …

Jiann-Ping Hsu College Of Public Health Magazine, Georgia Southern University

College of Public Health: News & Publications

• Message from the Dean: Stuart H. Tedders, PhD
• Remembering Dr. Evans Afriyie-Gyawu
• Exploring Research Focus Areas
• Alumni Feature: Overcoming Hurdles
• Research Feature: It's a weighted issue.
• Research Feature: The effectiveness of lactation cookies
• Period Equity Movement Earns National Recognition
• Leaving Her Mark
• Georgia on Our Mind
• Center for Addiction Recovery: Transforming Lives through Comprehensive Support
• Center for Public Health Practice and Research: The LEAD Academy: A Hospital Leadership Training Program
• Office of Practice and Research: Continued Engagement in Practice and Research
• Office of Teaching and Learning
• Office of Health Equity and Community: Engagement Continued Engagement in Practice and Research
• Awards, …

Factors Influencing Medication Adherence Among Adults Living With Diabetes And Comorbidities: A Qualitative Systematic Review, Kendall Gow, Amineh Qin, Lisa Whitehead

Research outputs 2022 to 2026

Purpose of review: Medication adherence plays an important role in improving health outcomes related to diabetes and comorbidity. The potential factors influencing medication adherence and how they contribute to health behaviors have not been synthesized to date. This review synthesized qualitative studies that identified factors influencing medication adherence among adults living with diabetes and comorbidity. Recent findings: Twenty-eight findings were extracted and synthesized into four themes: perceived support, lack of knowledge, medication issues, and the importance of routine. The findings highlight the factors that support medication adherence and areas that can be targeted to support and promote medication adherence. The …

Human In Vivo Medial Gastrocnemius Gear During Active And Passive Muscle Lengthening: Effect Of Inconsistent Methods And Nomenclature On Data Interpretation, Matheus Daros Pinto, Kazunori Nosaka, James M. Wakeling, Anthony J. Blazevich

Research outputs 2022 to 2026

‘Muscle gear’ is calculated as the ratio of fascicle-to-muscle length change, strain, or velocity. Inconsistencies in nomenclature and definitions of gear exist across disciplines partly due to differences in fascicle [curved (Lf) versus linear (Lf,straight)] and muscle [whole-muscle belly (Lb) versus belly segment (Lb,segment)] length calculation methods. We tested whether these differences affect gear magnitude during passive and active muscle lengthening of human medial gastrocnemius of young men (n=13, 26.3±5.0 years) using an isokinetic dynamometer. Lb, Lb,segment, Lf and Lf,straight were measured from motion analysis and ultrasound imaging data. Downshifts in belly gear but not belly segment gear occurred with …

Risk Of Low Energy Availability, Disordered Eating, And Menstrual Dysfunction In Female Recreational Runners, Marissa Miles

All Master's Theses

Running is characterized by high physiological demands with an emphasis on weight, which may lead to a greater risk of developing low energy availability (LEA) and/or disordered eating (DE). Recreational runners are a population that is often overlooked due to a lack of resources readily available to them. Purpose: This study investigated (1) the prevalence of menstrual dysfunction, risk of DE and LEA and (2) compare the risk of DE, training volume, and weight dissatisfaction between female recreational runners at risk for LEA versus not at risk for LEA. Methods: Female recreational runners (n= 1,923) completed an online questionnaire that …

Risk Of Low Energy Availability, Disordered Eating, And Menstrual Dysfunction In Female Collegiate Runners, Leah Louise Dambacher

All Master's Theses

Collegiate female distance runners may be at risk for low energy availability (LEA) due to increased exercise energy expenditure with or without decreased energy intake. Furthermore, this population has increased risk of disordered eating (DE), which can lead to LEA and negative health consequences, such as menstrual dysfunction (MD). Purpose: The purpose of this study was to: 1) investigate risk of LEA and DE and 2) compare DE, training volume, and weight dissatisfaction among female collegiate runners athletes at risk vs not at risk for LEA. Methods: Female runners (n = 287) who competed on an NCAA Division …

Identifying Unexpected Inflammation Resulting From Drug-Drug Interactions, Keegan Jolly

All Master's Theses

Adverse drug events result in nearly 1.3 million emergency room visits per year in the United States of America. As much as 30% of these adverse events are a result of drug-drug interactions (DDI’s). There is a gap in knowledge concerning these DDI outcomes especially when it comes to inflammation. Inflammation is linked to a variety of chronic health conditions and non-infectious diseases such as cancer. Purpose: The goal of this study was to examine how many active drug ingredients from FDA’s Adverse Event Reporting System (FAERS), when combined (in groups of two or more), elicit an inflammatory response …

Comparison Of Midwifery And Obstetric Care Among American Indian And Alaska Native Birthing People, Trista Barnhart

All Master's Theses

Despite making up only 3% of the U.S. population, American Indian/Alaska Native (AI/AN) individuals have the second highest maternal mortality rate in the United States, and the leading cause of maternal mortality and morbidity among AI/AN is postpartum hemorrhage. Many interventions used during childbirth have been identified as common causes of hemorrhage, such as lacerations of the vagina and cervix, operative vaginal deliveries, & augmentation of labor. Research has found that individuals who had midwives as their care providers have been found to be less likely to experience instrumental deliveries, epidural analgesia, labor augmentation, episiotomy or perineal lacerations, cesarean sections, …

Postpartum Depression And The Availability Of Support Resources In The Era Of Covid-19, Colleen Steward, Amy Claridge, Tishra Beeson, Sarah L. Feeney

All Master's Theses

The COVID-19 pandemic dramatically influenced women’s experience of pregnancy, labor, and the postpartum phase. New research shows rates of postpartum depression were higher than typical during the pandemic. This study expands on existing research by examining postpartum depression at 12-30 months postpartum and exploring the role of perceptions of access to social support in predicting depressive symptoms.

This survey assessed postpartum women’s perceptions of the availability of supports during the COVID-19 pandemic and whether access to support was associated with experiences of postpartum depression 12-30 months after birth. In total, 242 participants responded to an online survey including the Edinburgh …

Impact Of The Washington State Covid-19 Lockdown On 5-10-Year-Ol School-Aged Children Residing In Kitties County, Peyton Rondeau

All Master's Theses

Background: The Washington State COVID-19 lockdown and subsequent school closures brought increased dependency on parents to provide nutritious meals and opportunities for physical activity for their children.

Purpose: The aim of this study was to describe the impacts of the Washington State COVID-19 lockdown on the dietary, physical activity, and screen time habits of children ages 5-10-years-old residing in Kittitas County.

Methods: A researcher-developed Qualtrics survey was created and validated via the Index of Item Objective Congruence. The survey was administered to parents via Facebook, using local Kittitas County Facebook groups.

Results: Most parents identified that the Washington lockdown negatively …

Cannabis Cues And Effects On Social Anxiety, Erica Steinberg

All Master's Theses

Prior research has shown that individuals experiencing social anxiety may use cannabis for self-medication; therefore, the current study evaluated if viewing cannabis cues would reduce feelings of social anxiety. Central Washington University undergraduates enrolled in psychology courses (n = 124; 66.7% female; M_age = 19.8, SD_age = 4.7) were shown cannabis cues after viewing expressive facial images that prior research has shown induces feelings of social anxiety. Contrary to prior research, the current study found that emotional faces did not significantly affect state-trait anxiety as measured by the 6-item State-Trait Anxiety Inventory (STAI-6) but that trait social …

Clinical Practice Guideline For Best Practice Management Of Pediatric Patients By Chiropractors: Results Of A Delphi Consensus Process, Genevieve Keating, Cheryl Hawk, Lyndon Amorin-Woods, Deisy Amorin-Woods, Sharon Vallone, Ronald Farabaugh, Angela Todd, Randy Ferrance, Jessie Young, Stephanie O. Bhogal, Helen Sexton, Helen Alevaki, Joyce Miller, Gregory Parkin-Smith, Alec Schielke, Andrew Robinson, Robyn Thompson

Research outputs 2022 to 2026

Objective: To build upon existing recommendations on best practices for chiropractic management of children by conducting a formal consensus process and best evidence synthesis. Design: Best practice guide based on recommendations from current best available evidence and formal consensus of a panel of experienced practitioners, consumers, and experts for chiropractic management of pediatric patients. Methods: Synthesis of results of a literature search to inform the development of recommendations from a multidisciplinary steering committee, including experts in pediatrics, followed by a formal Delphi panel consensus process. Results: The consensus process was conducted June to August 2022. All 60 panelists completed the …

Therapeutic Frameworks In Integration Sessions In Substance-Assisted Psychotherapy: A Systematised Review, Sascha B. Thal, Paris Baker, Jonathon Marinis, Michelle Wieberneit, Jason M. Sharbanee, Raimundo Bruno, Petra M. Skeffington, Stephen J. Bright

Research outputs 2022 to 2026

Serotonergic psychedelics and related substances have been explored as potential adjuncts in substance-assisted psychotherapy (SAPT) for treating various disorders. SAPT can be divided into three phases: preparation, administration and integration. Integration is commonly defined as the comprehension and effective application of insights from psychedelic experiences into everyday life. However, there is limited research regarding the most appropriate therapeutic approach during SAPT. In this article, we discuss the current evidence for different therapeutic frameworks for integration sessions when serotonergic psychedelics and entactogens are used as adjuncts to psychotherapy. We conducted a systematised review of the literature following PRISMA guidelines and searched …