Medicine and Health Sciences Commons^™

Androgen Receptor Inhibition Suppresses Anti-Tumor Neutrophil Response Against Bone Metastatic Prostate Cancer Via Regulation Of Tβri Expression, Massar Alsamraae, Diane Costanzo-Garvey, Benjamin A. Teply, Shawna Boyle, Gary Sommerville, Zachary T. Herbert, Colm Morrissey, Alicia J. Dafferner, Maher Y. Abdalla, Rachel W. Fallet, Tammy Kielian, Heather Jensen Smith, Edson I. Deoliveira, Keqiang Chen, Ian A. Bettencourt, Ji Ming Wang, Daniel W. Mcvicar, Tyler Keeley, Fang Yu, Leah M. Cook

Journal Articles: Pathology and Microbiology

Bone metastatic disease of prostate cancer (PCa) is incurable and progression in bone is largely dictated by tumor-stromal interactions in the bone microenvironment. We showed previously that bone neutrophils initially inhibit bone metastatic PCa growth yet metastatic PCa becomes resistant to neutrophil response. Further, neutrophils isolated from tumor-bone lost their ability to suppress tumor growth through unknown mechanisms. With this study, our goal was to define the impact of metastatic PCa on neutrophil function throughout tumor progression and to determine the potential of neutrophils as predictive biomarkers of metastatic disease. Using patient peripheral blood polymorphonuclear neutrophils (PMNs), we identified that …

School Division Policies Related To Suicide Prevention And Response, David Naff, Fatemah A. Khawaji, Morgan Meadowes, Jill Flynn, Meg Sheriff, Lauren Powell, Lisa Gwyn, Tameka Burroughs, Jean Samuel

MERC Publications

Suicide is one of the leading causes of death among youth age 10-19, and is an increasing concern in the wake of COVID-19. K-12 schools are crucial spaces for offering mental health support to students, and can implement policies to help prevent suicidal thoughts and behaviors. This MERC research and policy brief focuses on education policy related to suicide prevention and response. It is structured to answer five questions: 1) What are recent trends in youth suicide? 2) What does research show about school division policies that are effective in suicide prevention and response? 3) What policies in Virginia and …

The Vaping Epidemic Among The Adolescent Population, Miranda O'Dell

Graduate Research Projects

No abstract provided.

Hiv And Addiction Services For People Who Inject Drugs: Healthcare Provider Perceptions On Integrated Care In The U.S. South, Davis Bradford, Mariel Parman, Sara Levy, Wesli H. Turner, Li Li, Leah Leisch, Ellen Eaton, Kaylee B. Crockett

APC Fund

This qualitative study evaluates physician training and experience with treatment and prevention services for people who inject drugs (PWID) including medications for opioid use disorder (MOUD) and HIV pre-exposure prophylaxis (PrEP). The Behavioral Model of Healthcare Utilization for Vulnerable Populations was applied as a framework for data analysis and interpretation. Two focus groups were conducted, one with early career physicians (n = 6) and one with mid- to late career physicians (n = 3). Focus group transcripts were coded and analyzed using thematic analysis to identify factors affecting implementation of treatment and prevention services for PWID. Respondents identified that increasing …

"I Haven’T Really Made Those Connections That Maybe Most Would Their First Year": A Qualitative Study Of The Covid-19 Pandemic And Student Social Capital Among 3 Cohorts Of First-Year Engineering Majors, Patricia Wonch Hill, Lance C. Pérez, Sohrab Asgarpoor, David Jones, Zachary George Short, Jennifer N. Rutt

UNL Office of Research and Innovation, Social/Behavioral Sciences Research Consortium

The COVID-19 pandemic disrupted the education of students of all ages and challenged teachers and academic support services to make major adaptations to continue to support student learning while also limiting the spread of the virus. Our team received an NSF grant in the Fall of 2018 to broaden participation in engineering by recruiting and retaining students who have been historically marginalized in engineering. We focused our research on first-year students who participated in pathway programs which provided peer and formal mentoring, success coaching, shared classes, and social activities, that would provide a sense of community and shared engineering identity …

Cat Part Iv: Occupational Therapy Interventions To Support Upper Extremity Spasticity In Older Adults Following A Stroke, Mary Redlin, Allie Reiffenberger, Shannon Ring, Aubrey Rude

Critically Appraised Topics

This critically appraised topic focuses on interventions for improving hand functions in activities of daily living (ADLs) for elderly adults who have chronic upper extremity spasticity following a stroke. For the purpose of this critically appraised topic, the focus will be on the elderly population, defined as being age 55 and older; research indicates stroke is most prevalent in this population (Mayo Clinic, 2022). When considering a particular theory, the Ecology of Human Performance (EHP) is the most suitable model for our focus question (Dunn, 2017). The Ecology of Human Performance is focused on the person and environment to increase …

The Impact Of Sensory Deprivation And Sensory-Based Intervention For Incarcerated Adults Over The Age Of 65, Kyara G. Crowley, Connor N. Fuchs, Sydney L. Johnson

Critically Appraised Topics

This critically appraised topic (CAT) focuses on sensory-based interventions for improving the quality of life for older adults who are incarcerated in the United States. There are many aspects to this topic; sensory deprivation in the prison system is addressed first, followed by the importance of sensory-based interventions, and finally the relationship between occupational therapy and quality of life.

Micro-Hardness Of The Radicular Dentine After Root Canal Irrigation With Salvadora Persica Extract: A Laboratory Study, Moataz Tarek Hekal, Enas Tawfik Enan, Noha Abdelmawla Elwassefy, Ahmad Mostafa Hussein

Mansoura Journal of Dentistry

Objectives: To evaluate the effect of the conventionally used irrigant sodium hypochlorite (NaOCL) compared to prepared Salvadora persica (miswak) root canal irrigant regarding the microhardness of root dentin.

Materials and methods: Forty-five extracted single-rooted mandibular premolars human teeth with closed apex were included in this study. Initially, the teeth were cleaned, prepared, and then disinfected, which were divided randomly into five equal groups according to the type of irrigant used [Group (1): saline (-ve control), Group (2): 5.25% NaOCl (+ve control), Group (3): 10% Miswak, Group (4): 15% Miswak and Group (5): 20% Miswak]. The specimens were embedded in acrylic …

Covid-19 And Eating Disorders: How Covid-19 Increased The Prevalence And Severity Of Eating Disorders, And The Lasting Implications, Lucy Rogers

Mahurin Honors College Capstone Experience/Thesis Projects

COVID-19 brought on a whirlwind of changes that were impossible to have foreseen. The impacts on individuals have left lasting impressions, the natures of which continue to be unearthed even now- 4 years later. This thesis will outline the impacts of COVID-19 on those suffering from eating disorders and disordered eating habits, as well as ideas for how to support and care for these individuals through their continued hardships which have been set in motion by the pandemic.

The research conducted on this topic utilized peer reviewed articles found through databases such as CINAHL, PubMed, and Cochrane Library. The findings …

Examining The Impact Of Holistic Practices On Lgbtqia+ Wellness, Airelle Railley

Mahurin Honors College Capstone Experience/Thesis Projects

The project involved surveying the before and aftereffects of holistic healing for ten undergraduate Kentuckians who identify as LGBTQIA+. The purpose of the project was to heighten and expand the LGBTQIA+ participants experience with holistic and wellness care, by utilizing on or off campus wellness activities. Those ten participants were split into two groups of five. The control group was lightly “encouraged” to attend any health and wellness activities. The intervention group was required to attend at least one yoga session per week. Each participant was instructed to complete and submit documentation each month. Those documents included surveys and monthly …

Effectiveness Of Nintendo Ring Fit In Improving Balance Deficits After Recovery From Acl Reconstruction, Emma Lord

Mahurin Honors College Capstone Experience/Thesis Projects

PURPOSE: This study aimed to assess the effectiveness of a gaming system in improving balance and strength after recovery from an anterior cruciate ligament reconstruction (ACLR). Existing bilateral deficits in strength and balance were also assessed among patients. METHODS: Four participants between the ages of 18-24 were recruited for this case-control study. Participants must have had ACL reconstruction surgery in the last 2 years, been discharged from formal physical therapy, and have a continued history of participating in physical activity at least three times a week. Participants were assigned to either the experimental or control groups using counterbalancing. The two …

Nurse Leader Burnout: A Pre-Survey/Post-Survey Quality Improvement Project, Shannon Martinez

Regis University Student Publications (comprehensive collection)

Title of the Project: Nurse Leader Burnout: A Pre-Survey/Post-Survey Quality Improvement Project

Objective/Purpose of the project: The objective of the project was to provide time for inpatient nurse leaders to take time to visit the resiliency room and or cart. The purpose of the study is to determine if scheduled use of the resiliency room and or cart can help improve nurse leaders’ ability to clear their mind and decrease burnout. Methods: Sample size of 17 inpatient nurse leaders at Sky Ridge Medical center were sent via Survey Monkey, a pre-survey using the Occupational Fatigue Recovery scale (OFERs). After …

Development And Implementation Of A Standardized Multimodal Nurse Training Program For The Placement Of Ultrasound-Guided Peripheral Intravenous (Usgpiv) Access, Timothy J. Belden

Regis University Student Publications (comprehensive collection)

Objective

The purpose of the quality improvement project was to develop and implement a standardized multimodal nurse training program following a fixed curriculum for the placement of USGPIV in patients with Difficult Venous Access (DVA) to increase nurse knowledge, self-efficacy, skill level, and increase the number of nurses proficient for independent placements.

Evaluation Methods

This project incorporated a quasi-experimental time series with a mixed methodology study design using purposeful and convenience sampling. Participant demographic and descriptive data were collected at the beginning of the training program. Additionally, quantitative data was collected by evaluating pre-test data, followed by post-test data collection …

An Unusual Cause Of Epicardial Coronary Artery Compression, Md Mashiul Alam, Michael Azrin, Muhammad Adeel

Posters

Atherosclerotic plaque rupture, embolization or dissection are the common causes of acute coronary artery occlusion. We present a case of iatrogenic external compression of right sided posterior descending artery (rPDA) by a chest tube.

Safety Profile Of Ultrasound Enhancing Agents In Echocardiography Across Yale New Haven Health System (Ynhhs), Md Mashiul Alam, Gini P. Jeyashanmugaraja, Robert L. Mcnamara Md, Evgeny Shkolnik

Posters

Ultrasound Enhancing Agents (UEAs) are increasingly used in echocardiography for delineation of endocardial border and detection of left ventricular (LV) thrombus with reported rate of serious adverse reactions from 0 to 0.029%. Contemporary utilization and safety data of UEA in echocardiography is scarce.

Autonomy And Paternalism In Medicine, Claire Consadine

Soaring: A Journal of Undergraduate Research

No abstract provided.

Current Concepts Of Treatment For Foot And Ankle Arthritis, Nehal Modha, Warren Windram

East Florida Division GME Research Day 2023

Foot and ankle arthritis is a prevalent and debilitating musculoskeletal condition that significantly impairs the quality of life for millions of individuals worldwide. This scientific abstract provides an overview of the current concepts of treatment for foot and ankle arthritis, highlighting the multifaceted approach employed by healthcare professionals to alleviate pain, improve function, and enhance the overall well-being of affected patients.

This comprehensive review outlines the key elements of contemporary foot and ankle arthritis management. First, it discusses the importance of early diagnosis and classification of the condition, emphasizing the role of advanced imaging modalities and clinical assessments in establishing …

Outcome Disparity Among African Americans Following Colon Trauma, Joseph Krocker, Victoria Lord, Tamar Walker, Tammy Luan, Luis Rivera Aguasvivas, Jonathan Meizoso, Heidi Bahna, Juliet Ray

East Florida Division GME Research Day 2023

Introduction: African Americans (AA) are more likely to experience violence-related trauma compared to White subjects and experience poorer outcomes in many facets of traumatic injury. However, previous analysis of males with penetrating colon trauma has identified no difference in mortality and decreased morbidity in AAs compared to Whites. Outcomes in AAs following colon injury requiring surgery are assessed in the current study.

Methods: The Trauma Quality Improvement Program (TQIP) was queried for subjects requiring colon surgery within 24 hours of admission from 2017-2019. Mortality was the primary outcome and secondary outcomes included intensive care unit (ICU) days, total length of …

Plantar Plate Injury: Current Treatment Options, Nehal Modha, Warren Windram

East Florida Division GME Research Day 2023

Plantar plate injuries have gained recognition as a common cause of forefoot pain and instability. This review aims to comprehensively analyze the present landscape of treatment options available for addressing plantar plate injuries.

A comprehensive literature review was completed by the authors using Google Scholar, Pubmed, Cochrane Review, and Science Direct using a combination of phrases related to the title of this article that discussed various treatment modalities for plantar plate injuries. The review encompassed both non-surgical and surgical interventions, assessing their efficacy, outcomes, and potential complications.

Conservative approaches, such as rest, taping, orthotic devices, and physical therapy, have been …

Western Buddhism And Transpersonal Psychology: Cross-Hermeneutic And Engaged Approaches, Debashish Banerji

International Journal of Transpersonal Studies

Contemporary Buddhism has been fashioned from cross-cultural interactions between a long history of Asian traditions and the expansionist drive of modernity. As part of this engagement, Buddhism, particularly in the West, has developed a close relation with transpersonal psychology. This essay forms an introduction to the special issue of articles approaching this relation between Buddhism and psychology in different ways. While some articles probe the difference in aims of the two disciplines, some are concerned with the decontextualized uses of Buddhist techniques such as mindfulness, some explore the possibilities of Buddhist practice in cognitive or other psychological terms and some …

Zen And The Art Of Doughnut Economics: When Limits Are Strangely Liberating, Peter Doran

International Journal of Transpersonal Studies

Kate Raworth's celebrated book, Doughnut Economics: Seven ways to think like a 21st century economist, calls for a reconciliation of our design principles for society and the economy with the rhythms and tolerances of ecological systems. It will demand something akin to a new axial revolution that will have to be experienced as much in the body and in the intimacies of a renewed care and appreciation for our relational and ecological selves as in the collective re-design of our societies, democratic decision-making and collective provisioning. Buddhist scholarship offers a distinctive contribution to this conversation invoked in a book that …

Incidence And Prevalence Of Keratoconus Based On Scheimpflug Imaging, Elsie Chan, Elaine W. Chong, Samantha Sze-Yee Lee, Maria Franchina, Seyhan Yazar, Peter Eastwood, Nigel Mcardle, David A. Mackey, Gareth Lingham

Articles

The prevalence of keratoconus (Belin/Ambrόsio Enhanced Ectasia Display Score ≥2.6 on Scheimpflug imaging) in a longitudinal, community cohort study from Western Australia was 3.4% (n=26/755). Keratoconus incidence over an 8-year period was 2.2% (n=15/669).

Agricultural Dust Derived Bacterial Extracellular Vesicle Mediated Inflammation Is Attenuated By Dha, Art J. Heires, Derrick R. Samuelson, Daniel Villageliu, Tara M. Nordgren, Debra J. Romberger

Journal Articles: Pulmonary & Critical Care Med

Dietary long-chain omega-3 polyunsaturated fatty acids (n-3 PUFA) and their pro-resolving metabolites are protective against atherosclerotic disease, and ameliorate systemic inflammatory conditions including lupus erythematosus, psoriasis, and bronchial asthma. Organic bioaerosol inhalation is a common and injurious hazard associated with agricultural occupations such as work in swine concentrated animal feeding operations (CAFOs) and is known to increase the risk for developing respiratory conditions such as asthma and COPD. Nearly all cells secrete membrane-bound vesicles (extracellular vesicles, EVs) that have the capacity to transmit protein, nucleic acid, and lipid signaling mediators between cells. Using a polymer-based isolation technique (ExoQuick, PEG) followed …

Icenticaftor, Novel Therapy For Copd: This Glass Is Half Full, Stephen I. Rennard

Journal Articles: Pulmonary & Critical Care Med

No abstract provided.

Interstitial Lung Disease And Heart Failure In A 75 Year Old Guitar Maker, Andrew Kim, Elizabeth Benge, Cristian Valdez, Tony Alarcon, Yema Jalal

Far West Division GME Research Day 2023

No abstract provided.

Regional Fa Values And Loss Of Consciousness In Mild Traumatic Brain Injury, Alexander Asturias, Thomas Knoblauch, Alan Rodriguez, Cheryl Vanier, Caroline Le Tohic, Brandon Barrett, Michael Eisenberg, Rachelle Gibbert, Lennon Zimmerman, Shaunaq Parikh, Anh Nguyen, Sherwin Azad, Leo Germin, Enrico Fazzini, Travis Snyder

Far West Division GME Research Day 2023

No abstract provided.

Perforated Congenital Sigmoid Diverticula Of A Pediatric Patient, Tamir Bresler, Ryan Meyer, Kevin Palmer, Philip Frykman

Far West Division GME Research Day 2023

No abstract provided.

Persistent Left Side Superior Vena Cava, Kevin Palmer, Ryan Meyer, Tamir Bresler, Hunter King, Marissa Defreese

Far West Division GME Research Day 2023

No abstract provided.

Spontaneous Heterotopic Pregnancy: Diagnosis And Management, Katie P. Nguyen, Marlekah Hudspeth, Honey Milestone

Far West Division GME Research Day 2023

No abstract provided.

A Case Of Thrombolytic Associated Ich In The Setting Of Infective Endocarditis, Priscilla Yan, Lama Al-Khoury

Far West Division GME Research Day 2023

No abstract provided.