Medicine and Health Sciences Commons^™

Implicit Bias Mask: (Gettin' The) Best Of Me, Julia Malewicz, Nasser Junedi, Kirsten Brinkmeier, Alisha Williams, Hovhannes Hayrapetyan, John Gallagher

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Internalizing The Medical Student Identity, Samantha Odeesho, Brennan Burrows, Nickolas Vinokurov, Gabriella Cascio, Sumeet Saini, Tiffany Chu

Patient Education Projects

No abstract provided.

Implicit Bias Mask: The Value Of Time In Medical School, Markiesha Baines, Arifbillah Sarowar, Saachi Mittal, Meaghan Osborne, Karthik Babu Kolisetty, Connor Sakis

Patient Education Projects

No abstract provided.

Implementation Of Mrsa Nasal Swabs As An Antimicrobial Stewardship Intervention To Decrease Anti-Mrsa Therapy In Covid-19 Infection, Alaina Dekerlegand, Emily Johnston, Britney Mellor, Melanie Rae Schrack, Catherine O’Neal

School of Medicine Faculty Publications

In the early stages of treating patients with SARS-CoV-2, limited information was available to guide antimicrobial stewardship interventions. The COVID-19 Task Force and Antimicrobial Stewardship Committee, at a 988-bed academic medical center, implemented the use of methicillin-resistant Staphylococcus aureus (MRSA) nasal swab polymerase chain reaction (PCR) testing to assist with the de-escalation of anti-MRSA therapy in patients with suspected superimposed bacterial pneumonia in COVID-19. A retrospective study was conducted to evaluate the impact of MRSA nasal swab PCR testing on the rate of anti-MRSA therapy between 13 April 2020 and 26 July 2020. A total of 122 patients were included …

4d Lung Mri With High-Isotropic-Resolution Using Half-Spoke (Ute) And Full-Spoke 3d Radial Acquisition And Temporal Compressed Sensing Reconstruction, Can Wu, Guruprasad Krishnamoorthy, Victoria Yu, Ergys Subashi, Andreas Rimner, Ricardo Otazo

Faculty, Staff and Student Publications

Objective:

To develop a respiratory motion-resolved 4D MRI technique with high-isotropic-resolution (1.1 mm) using 3D radial sampling, camera-based respiratory motion sensing, and temporal compressed sensing reconstruction for lung cancer imaging.

Approach:

Free-breathing half- and full-spoke 3D golden-angle radial acquisitions were performed on eight healthy volunteers and eight patients with lung tumors of varying size. A back-and-forth k-space ordering between consecutive interleaves of the 3D radial acquisition was performed to minimize eddy current-related artifacts. Data were sorted into respiratory motion states using camera-based motion navigation and 4D images were reconstructed using temporal compressed sensing to reduce scan time. Normalized sharpness indices …

Monitoring And Modulating Diet And Gut Microbes To Enhance Response And Reduce Toxicity To Cancer Treatment, Anne Knisely, Yongwoo David Seo, Jennifer A Wargo, Manoj Chelvanambi

Faculty, Staff and Student Publications

The gut microbiome comprises a diverse array of microbial species that have been shown to dynamically modulate host immunity both locally and systemically, as well as contribute to tumorigenesis. In this review, we discuss the scientific evidence on the role that gut microbes and diet play in response and toxicity to cancer treatment. We highlight studies across multiple cancer cohorts that have shown an association between particular gut microbiome signatures and an improved response to immune checkpoint blockade, chemotherapy, and adoptive cell therapies, as well as the role of particular microbes in driving treatment-related toxicity and how the microbiome can …

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

Nebraska Center for Virology: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

Nebraska Center for Virology: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

School of Veterinary and Biomedical Sciences: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …

Vaccines Against Group B Coxsackieviruses And Their Importance, Kiruthiga Mone, Ninaad Lasrado, Meghna Sur, Jay Reddy

School of Veterinary and Biomedical Sciences: Faculty Publications

The group B coxsackieviruses (CVBs) exist in six serotypes (CVB1 to CVB6). Disease associations have been reported for most serotypes, and multiple serotypes can cause similar diseases. For example, CVB1, CVB3, and CVB5 are generally implicated in the causation of myocarditis, whereas CVB1 and CVB4 could accelerate the development of type 1 diabetes (T1D). Yet, no vaccines against these viruses are currently available. In this review, we have analyzed the attributes of experimentally tested vaccines and discussed their merits and demerits or limitations, as well as their impact in preventing infections, most importantly myocarditis and T1D.

Using Cognitive Interviews To Improve A Measure Of Organizational Readiness For Implementation, Maria Mcclam, Lauren Workman, Emanuelle M Dias, Timothy J Walker, Heather M Brandt, Derek W Craig, Robert Gibson, Andrea Lamont, Bryan J Weiner, Abraham Wandersman, Maria E Fernandez

Faculty, Staff and Student Publications

BACKGROUND: Organizational readiness is a key factor for successful implementation of evidence-based interventions (EBIs), but a valid and reliable measure to assess readiness across contexts and settings is needed. The R = MC

METHODS: We conducted 20 cognitive interviews with FQHC staff (clinical and non-clinical) in South Carolina and Texas. Participants were provided a subset of items from the readiness survey to review. A semi-structured interview guide was developed to elicit feedback from participants using "think aloud" and probing techniques. Participants were recruited using a purposive sampling approach and interviews were conducted virtually using Zoom and WebEx. Participants were asked …

Updated Documentation Requirements, Michael Gratson

Website/Multimedia Contributions

No abstract provided.

Inhibition Of Colorectal Cancer Tumorigenesis By Ursolic Acid And Doxorubicin Is Mediated By Targeting The Akt Signaling Pathway And Activating The Hippo Signaling Pathway, Dan Hu, Ruo Yu Meng, Thi Van Nguyen, Ok Hee Chai, Byung Hyun Park, Ju-Seog Lee, Soo Mi Kim

Faculty, Staff and Student Publications

Colorectal cancer (CRC) is one of the deadliest malignant tumors worldwide and its prevalence is increasing in South Korea. The efficacy of combined treatment with natural product‑derived and chemotherapy agents including curcumin combined with 5‑fluorouracil, resveratrol combined with cisplatin and epigallocatechin‑3‑gallate (EGCG) combined with cisplatin in preventing cancer progression and killing cancer cells has emerged. The Akt and Hippo signaling pathways serve a key role in colorectal tumor growth; however, the exact role of the crosstalk between Akt and Hippo signaling pathways in CRC remains poorly elucidated. The combined effect of UA and DOX on the cell proliferation, apoptosis, migration …

Postbiotics Derived From L Paracasei Et-22 Inhibit The Formation Of S Mutans Biofilms And Bioactive Substances: An Analysis, Zhi Zhao, Jianmin Wu, Zhe Sun, Jinbo Fan, Fudong Liu, Wen Zhao, Wei-Hsien Liu, Ming Zhang, Wei-Lian Hung

Faculty, Staff and Student Publications

Globally, dental caries is one of the most common non-communicable diseases for patients of all ages; Streptococcus mutans (S. mutans) is its principal pathogen. Lactobacillus paracasei (L. paracasei) shows excellent anti-pathogens and immune-regulation functions in the host. The aim of this study is to evaluate the effects of L. paracasei ET-22 on the formation of S. mutans biofilms. The living bacteria, heat-killed bacteria, and secretions of L. paracasei ET-22 were prepared using the same number of bacteria. In vitro, they were added into artificial-saliva medium, and used to coculture with the S. mutans. Results showed …

Implicit Bias Mask: Inner Beauty And Heroic Strength, Madilyn Mason, Jesse Kato, Samaah Saifullah, Brandon Brown, Hasti Nema

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Visualizing Success, Shrila Rajendran, Timothy Li, Daniel Saxon, Andrew Lemmen, Jourdyn Lao, Devun Birk

Patient Education Projects

No abstract provided.

Implicit Bias Mask: If These Walls Could Talk, Pranav Gopalakrishnan, Christopher Carter, Neha Chava, William Mcroy, Mai Daigle, Stephanie Schervish

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Beneath The Veneer Of Resilience, Daphne Pate, Peter Nolan, Anusha Vavilikolanu, Abrielle Fretz, Cassandra Pecarski, Trisha Ray

Patient Education Projects

No abstract provided.

Implicit Bias Mask: (H.E.A.L)2, Tannia M. Rodriguez, Leane Kuo, Anah Salgat, Mitchell Wu, Gabriella Gonzales, Jacob Dougherty

Patient Education Projects

No abstract provided.

Implicit Bias Mask: A Journey To Find Balance, Tiffany Mckenney, Nathan Li, Eve Sherbin, Jeremy Taigman, Pranally Desai, Brock Bradley

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Pressures And Perceptions, Kimera Harris, Hani Nasr, Cornelius Lau, Ciara White

Patient Education Projects

No abstract provided.

Implicit Bias Mask: The Me I Want You To See, Susan Hartzell, Jose Lopez, Elli Johnson, Alexa Bernard, Theodore Schiff, Jackson Ferris

Patient Education Projects

No abstract provided.

Implicit Bias Mask: The Pursuit Of Knowledge, Brianna Regan, Tareq Hanna, Thomas Deppong, Maya Kohavi, Zarin Kothari, Ahmed Jafri

Patient Education Projects

No abstract provided.

Implicit Bias Mask: The Path To Achieving Our Goals, Cyra Kharas, Robert Leone, Mihika Sridhar, Sophia Gandarillas, Paul Villa

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Understanding What It Means To Be A "Life-Long Learner" Both Inside The Classroom And In The Community, Meet Patel, Sohini Pandit, Sara Naessig, Neil Garg, Lara Rostomian

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Pillars Of Personality, Jane Dow, Ingrid Rocha, Karamoja Monchamp, Max Jones, Arhan Shetty, Chase Aaron

Patient Education Projects

No abstract provided.

Implicit Bias Mask: “Inside Out”, Arainya Durham, Khush Hussain, Shruthi Ilango, Samantha Markowitz, James Soetedjo, Jacob Hall

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Humanity In Medical School, Laila Al-Jerdi, Elizabeth Helfrich, Noah Robertson, Sean Williams, Tobin Smith, Nicole Lafrance

Patient Education Projects

No abstract provided.

Implicit Bias Mask: The Inner Us; The Struggles And Identities That Truly Make Us Individuals, Curtis Mack, Angelica Cabatu, Era Cobani, Carly Abrahams, Michal Ruprecht, Nicholas Apostolakis

Patient Education Projects

No abstract provided.

Implicit Bias Mask: Perseverance In Medical School, Deepa Raghavan, Dipra Debnath, Ranya Krayem, Constance Cleveland, Jay Maixner, Zane Mustafa

Patient Education Projects

No abstract provided.