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2023

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Articles 1981 - 2010 of 27433

Full-Text Articles in Medicine and Health Sciences

Latinx Social Work Students’ Well-Being Prior To And During The Covid-19 Pandemic, Leyla Feize Nov 2023

Latinx Social Work Students’ Well-Being Prior To And During The Covid-19 Pandemic, Leyla Feize

School of Social Work Faculty Publications

This is a reflection on social work students’ well-being before and during the COVID-19 pandemic. This narrative was indirectly written by the students, as it is their interpretations of their feelings, thoughts, and behaviors derived from drawing their own mandalas daily for one month. It is a comparison of two stories of struggle, hope, and change during two different periods which were close in time, but far in reality.


Improving Access To Care For Specialty Pediatric Orthopedic Patients: Maximizing Telehealth To Achieve Outcomes, Tammy Keesey Nov 2023

Improving Access To Care For Specialty Pediatric Orthopedic Patients: Maximizing Telehealth To Achieve Outcomes, Tammy Keesey

Student Scholarly Projects

Practice Problem: The lack of resources such as transportation, insurance, and finances can negatively impact a patient’s access to much-needed specialty care. Providing education, assessing telehealth literacy, and creating a specific process for identifying appropriate telehealth visits can improve pediatric specialty access to care.

PICOT: The PICOT question for this project was: In pediatric orthopedic clinic patients (P), what is the impact of the active introduction of telehealth as a clinic visit option (I) versus the current standard passive process of scheduling telehealth visits (C) on the rates of access to care (O) after nine total weeks of …


Characteristic Dynamic Functional Connectivity During Sevoflurane-Induced General Anesthesia, J. Miao, M. Tantawi, Mahdi Alizadeh, Sara Thalheimer, Faezeh Vedaei, Victor Romo, Feroze B. Mohamed, Chengyuan Wu Nov 2023

Characteristic Dynamic Functional Connectivity During Sevoflurane-Induced General Anesthesia, J. Miao, M. Tantawi, Mahdi Alizadeh, Sara Thalheimer, Faezeh Vedaei, Victor Romo, Feroze B. Mohamed, Chengyuan Wu

Department of Neurosurgery Faculty Papers

General anesthesia (GA) during surgery is commonly maintained by inhalational sevoflurane. Previous resting state functional MRI (rs-fMRI) studies have demonstrated suppressed functional connectivity (FC) of the entire brain networks, especially the default mode networks, transitioning from the awake to GA condition. However, accuracy and reliability were limited by previous administration methods (e.g. face mask) and short rs-fMRI scans. Therefore, in this study, a clinical scenario of epilepsy patients undergoing laser interstitial thermal therapy was leveraged to acquire 15 min of rs-fMRI while under general endotracheal anesthesia to maximize the accuracy of sevoflurane level. Nine recruited patients had fMRI acquired during …


Correction: Precision Dosimetry In Yttrium-90 Radioembolization Through Ct Imaging Of Radiopaque Microspheres In A Rabbit Liver Model, E Courtney Henry, Matthew Strugari, George Mawko, Kimberly Brewer, David Liu, Andrew C Gordon, Jeffrey N Bryan, Charles Maitz, James J Karnia, Robert Abraham, S Cheenu Kappadath, Alasdair Syme Nov 2023

Correction: Precision Dosimetry In Yttrium-90 Radioembolization Through Ct Imaging Of Radiopaque Microspheres In A Rabbit Liver Model, E Courtney Henry, Matthew Strugari, George Mawko, Kimberly Brewer, David Liu, Andrew C Gordon, Jeffrey N Bryan, Charles Maitz, James J Karnia, Robert Abraham, S Cheenu Kappadath, Alasdair Syme

Faculty, Staff and Student Publications

No abstract provided.


Autogenous Reproduction By Ornithodoros Turicata (Ixodida: Argasidae) Females And Vertical Transmission Of The Tick-Borne Pathogen Borrelia Turicatae (Spirochaetales: Borreliaceae), Serhii Filatov, Aparna Krishnavajhala, Job E Lopez Nov 2023

Autogenous Reproduction By Ornithodoros Turicata (Ixodida: Argasidae) Females And Vertical Transmission Of The Tick-Borne Pathogen Borrelia Turicatae (Spirochaetales: Borreliaceae), Serhii Filatov, Aparna Krishnavajhala, Job E Lopez

Faculty, Staff and Students Publications

Ornithodoros turicata is a vector of relapsing fever spirochetes in North America and transmits Borrelia turicatae to a variety of vertebrate hosts. The remarkably long lifespan of O. turicata and its ability to maintain spirochetes horizontally (between life stages) and vertically (to progeny) promote the perpetuation of B. turicatae in nature. Nevertheless, the reproductive biology of O. turicata is poorly understood. In this report, we collected ticks from a park within a neighborhood of Austin, TX. They were reared to adulthood, and male ticks were individually housed with females. We observed autogenous reproduction, which is the ability to produce eggs …


Heartburn's Hidden Impact: A Narrative Review Exploring Gastroesophageal Reflux Disease (Gerd) As A Cardiovascular Disease Risk Factor, Jacob J Gries, Bing Chen, Salim S Virani, Hafeez Ul Hassan Virk, Hani Jneid, Chayakrit Krittanawong Nov 2023

Heartburn's Hidden Impact: A Narrative Review Exploring Gastroesophageal Reflux Disease (Gerd) As A Cardiovascular Disease Risk Factor, Jacob J Gries, Bing Chen, Salim S Virani, Hafeez Ul Hassan Virk, Hani Jneid, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Gastroesophageal reflux disease (GERD) is a very common disease with an estimated 442 million cases worldwide. It is a well-documented independent risk factor for many gastrointestinal pathologies, however, its role in cardiovascular disease (CVD) is unclear, despite its high prevalence in patients with CVD. Although traditionally considered a causative agent of noncardiac chest pain, a common imitator of cardiac chest pain, or an incidentally shared comorbidity in patients with CVD, a number of studies have implicated GERD and its therapies as risk factors for CVD. This narrative review will explore the relationship between GERD and CVD, including medical and mechanical …


Gastrointestinal: A Rare Case Of Concurrent Vulvar Crohn's Disease And Pyoderma Gangrenosum, J. Bommireddipally, K. Broussard, H. Osman, A. Uhlhorn, N. Loganantharaj Nov 2023

Gastrointestinal: A Rare Case Of Concurrent Vulvar Crohn's Disease And Pyoderma Gangrenosum, J. Bommireddipally, K. Broussard, H. Osman, A. Uhlhorn, N. Loganantharaj

School of Medicine Faculty Publications

No abstract provided.


A Youth-Centred Approach To Improving Engagement In Hiv Services: Human-Centred Design Methods And Outcomes In A Research Trial In Kisumu County, Kenya, Eliud Omondi Akama, Thomas Odeny, Ingrid Eshun-Wilson, Elvin H Geng, Et Al. Nov 2023

A Youth-Centred Approach To Improving Engagement In Hiv Services: Human-Centred Design Methods And Outcomes In A Research Trial In Kisumu County, Kenya, Eliud Omondi Akama, Thomas Odeny, Ingrid Eshun-Wilson, Elvin H Geng, Et Al.

2020-Current year OA Pubs

UNLABELLED: IntroductionInnovative interventions are needed to improve HIV outcomes among adolescents and young adults (AYAs) living with HIV. Engaging AYAs in intervention development could increase effectiveness and youth acceptance, yet research is limited. We applied human-centred design (HCD) to refine adherence-support interventions pretrial and assessed HCD workshop acceptability.

METHODS: We applied an iterative, four-phased HCD process in Kenya that included: (1) systematic review of extant knowledge, (2) prioritisation of design challenges, (3) a co-creation workshop and (4) translation tables to pair insights with trial intervention adaptations. The co-creation workshop was co-led by youth facilitators employing participatory activities to inform intervention …


Functional Analysis Of Recurrent Cdc20 Promoter Variants In Human Melanoma, Paula M Godoy, Abimbola Oyedeji, Jacqueline L Mudd, Vasilios A Morikis, Anna P Zarov, Gregory D Longmore, Ryan C Fields, Charles K Kaufman Nov 2023

Functional Analysis Of Recurrent Cdc20 Promoter Variants In Human Melanoma, Paula M Godoy, Abimbola Oyedeji, Jacqueline L Mudd, Vasilios A Morikis, Anna P Zarov, Gregory D Longmore, Ryan C Fields, Charles K Kaufman

2020-Current year OA Pubs

Small nucleotide variants in non-coding regions of the genome can alter transcriptional regulation, leading to changes in gene expression which can activate oncogenic gene regulatory networks. Melanoma is heavily burdened by non-coding variants, representing over 99% of total genetic variation, including the well-characterized TERT promoter mutation. However, the compendium of regulatory non-coding variants is likely still functionally under-characterized. We developed a pipeline to identify hotspots, i.e. recurrently mutated regions, in melanoma containing putatively functional non-coding somatic variants that are located within predicted melanoma-specific regulatory regions. We identified hundreds of statistically significant hotspots, including the hotspot containing the TERT promoter variants, …


Blobcut: A Contrastive Learning Method To Support Small Blob Detection In Medical Imaging, Teng Li, Yanzhe Xu, Teresa Wu, Jennifer R Charlton, Kevin M Bennett, Firas Al-Hindawi Nov 2023

Blobcut: A Contrastive Learning Method To Support Small Blob Detection In Medical Imaging, Teng Li, Yanzhe Xu, Teresa Wu, Jennifer R Charlton, Kevin M Bennett, Firas Al-Hindawi

2020-Current year OA Pubs

Medical imaging-based biomarkers derived from small objects (e.g., cell nuclei) play a crucial role in medical applications. However, detecting and segmenting small objects (a.k.a. blobs) remains a challenging task. In this research, we propose a novel 3D small blob detector called BlobCUT. BlobCUT is an unpaired image-to-image (I2I) translation model that falls under the Contrastive Unpaired Translation paradigm. It employs a blob synthesis module to generate synthetic 3D blobs with corresponding masks. This is incorporated into the iterative model training as the ground truth. The I2I translation process is designed with two constraints: (1) a convexity consistency constraint that relies …


Helicobacter Pylori And Intestinal Parasites Co-Infection: Estimation Of Risk Factors Among Dyspeptic Patients In Mukalla City, Hadhramout, Yemen, Eidha Ali Bin-Hameed Bin-Hameed, Huda Mohammed Barajash Barajash Nov 2023

Helicobacter Pylori And Intestinal Parasites Co-Infection: Estimation Of Risk Factors Among Dyspeptic Patients In Mukalla City, Hadhramout, Yemen, Eidha Ali Bin-Hameed Bin-Hameed, Huda Mohammed Barajash Barajash

Hadhramout University Journal of Natural & Applied Sciences

The prevalence of Helicobacter pylori (H. pylori) infection among dyspeptic patients was common in developing countries. H. pylori is capable of colonizing the gastric mucosa, and the infections often lead to the development of various gastrointestinal complaints. Human colonization by H. pylori and intestinal parasites is also common. This study aimed to estimate the prevalence co-infection of H. pylori and intestinal parasites and associated risk factors among dyspeptic patients referred to Mukalla city hospitals, Hadhramout, Yemen. In this cross-sectional study, one hundred stool samples were collected and diagnosed for detection H. pylori infection by rapid immunochromatographic stool-based antigen …


Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole Nov 2023

Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole

Journal of Health Disparities Research and Practice

Due to the underutilization of screening mammography, African American women (AAW) are more likely to experience negative health outcomes after receiving a late-stage breast cancer diagnosis than White Women (WW). The purpose of this article is to examine the roles of the media, health community and the African American church and pastor and their potential impact in AAW screening decisions. Fifteen AAW, ages 45 and older, were invited to participate in a semi-structured interview. Most women agreed the African American pastor and church as well as the health community, and media are an integral part of their lives. Therefore, specific …


Covid-19 Severity Among American Indians And Alaska Natives In 16 States - January 1, 2020, To March 31, 2021, Jessica Arrazola, Scott Erickson, Chiao Wen Lan, Adrian Dominguez, Sujata Joshi, Andria Apostolou, Ashley Busacker, David Casey, Christiana Coyle, Kathryn Helfrich, Jennifer Kraszewski, Thomas Kim, Genelle Lamont, Richard Leman, Pamela Lemaster, Nick Lehnertz, Mike Mannell, Dakota Matson, Alex Merrill, Tracy Miller, Benjamin Schram, Ozair Naqvi, Samantha Rice, Samantha Hyde-Rolland, Alyssa Rowell, Dean Seneca, Victoria Warren-Mears, Laura Williamson Nov 2023

Covid-19 Severity Among American Indians And Alaska Natives In 16 States - January 1, 2020, To March 31, 2021, Jessica Arrazola, Scott Erickson, Chiao Wen Lan, Adrian Dominguez, Sujata Joshi, Andria Apostolou, Ashley Busacker, David Casey, Christiana Coyle, Kathryn Helfrich, Jennifer Kraszewski, Thomas Kim, Genelle Lamont, Richard Leman, Pamela Lemaster, Nick Lehnertz, Mike Mannell, Dakota Matson, Alex Merrill, Tracy Miller, Benjamin Schram, Ozair Naqvi, Samantha Rice, Samantha Hyde-Rolland, Alyssa Rowell, Dean Seneca, Victoria Warren-Mears, Laura Williamson

Journal of Health Disparities Research and Practice

Objective: To compare rates and risk factors of severe COVID-19-related outcomes between American Indian/Alaska Native (AI/AN) and non-Hispanic White people (NHW).

Methods: Aggregate Social Vulnerability Index (SVI), COVID-19-related risk factor, hospitalization, and mortality data were obtained from 16 states for January 1, 2020-March 31, 2021. Generalized estimating equation Poisson regression models calculated age-adjusted cumulative incidences, incidence ratios (IR), and 95% confidence intervals (CI) comparing AI/AN and NHW persons by age, sex, and county-level SVI status.

Results: Race data were missing for 42.7% of COVID-19 cases, 24.7% of hospitalizations, and 10.1% of deaths. Risk of AI/AN COVID-19 mortality …


Understanding Firearm Purchasing During A Purchasing Surge Among Black Individuals, Esprene Liddell-Quintyn, Jasmin Brooks Stephens, Michael D. Anestis Nov 2023

Understanding Firearm Purchasing During A Purchasing Surge Among Black Individuals, Esprene Liddell-Quintyn, Jasmin Brooks Stephens, Michael D. Anestis

Journal of Health Disparities Research and Practice

Abstract

Purpose: During 2020, the US experienced a record-breaking year for firearm purchases, with major spikes occurring at the beginning of the COVID-19 pandemic in March 2020, and in June 2020. This study aimed to examine the factors associated with firearm purchasing during a purchasing surge among Black individuals and to document their reasons for surge purchasing.

Methods: We conducted a cross sectional survey from January to June 2021. Participants were recruited through quota sampling using Qualtrics. This study focuses on a sample of Black individuals (n=1115) from which a subsample of respondents (n=108) indicated that they purchased firearms since …


Pili Pono Practice: A Qualitative Study On Reimagining Native Hawaiian Food Sovereignty Through Malama Backyard Aquaponics, Pahonu Coleman, Samantha Keaulana, J Kahaulahilahi Vegas, Phoebe W. Hwang, Leshay Keliiholokai, Jane J. Chung-Do, Ikaika Rogerson, Ilima Ho-Lastimosa Nov 2023

Pili Pono Practice: A Qualitative Study On Reimagining Native Hawaiian Food Sovereignty Through Malama Backyard Aquaponics, Pahonu Coleman, Samantha Keaulana, J Kahaulahilahi Vegas, Phoebe W. Hwang, Leshay Keliiholokai, Jane J. Chung-Do, Ikaika Rogerson, Ilima Ho-Lastimosa

Journal of Health Disparities Research and Practice

Living in one of the most remote island chains in the world, Native Hawaiians developed sophisticated food cultivation systems that sustained a thriving and robust population for centuries. These systems were disrupted by colonization, which has contributed to the health disparities that Native Hawaiians face today. MALAMA, a culturally-grounded backyard aquaponics program, was developed to promote food sovereignty among Native Hawaiians. This study utilized participant interview and focus group data to identify how participating in the MALAMA program impacts the wellbeing. The findings demonstrate that MALAMA enhanced the participants’ pilina (relationship, connection) to traditional foods, land, cultural identity, family, and …


Prevalence Of Central Venous Stenosis Among Black And White Eskd Patients With Dysfunctional Dialysis Access, Vipul Chitalia Md, Jonathan Ravid, Arinze Nkiruka, Kristina Yamkovoy, Matthew Diamond, Rohit Pillai, Tyler J. Ryan, Saran Lotfollahzadeh, Janice Weinberg, Alik Farber, Rajendran Vivendhan, Jean Francis, Nathanael Fillmore, Najia Idrees Nov 2023

Prevalence Of Central Venous Stenosis Among Black And White Eskd Patients With Dysfunctional Dialysis Access, Vipul Chitalia Md, Jonathan Ravid, Arinze Nkiruka, Kristina Yamkovoy, Matthew Diamond, Rohit Pillai, Tyler J. Ryan, Saran Lotfollahzadeh, Janice Weinberg, Alik Farber, Rajendran Vivendhan, Jean Francis, Nathanael Fillmore, Najia Idrees

Journal of Health Disparities Research and Practice

In the United States, significant racial and ethnic disparities exist in chronic kidney disease (CKD) and its management. Hemodialysis constitutes the main stay of renal replacement therapy for end-stage kidney disease (ESKD), which is initiated using central venous catheters (CVC) in most CKD patients in the United States. Black ESKD patients have higher usage and greater time on CVC for hemodialysis compared to White patients. This trend places Black patients at a potentially higher risk for CVC-related complications such as central venous stenosis (CVS). We posited that Black patients would have a higher prevalence and a greater risk of CVS. …


Treatment Of Refractory Ventricular Tachycardia With Radiofrequency Ablation And Temporary Mechanical Circulatory Support, Som P. Singh, Alejandro Vidal Margenat, David L. Boone, Ellen Condoure, Ramesh Hariharan Nov 2023

Treatment Of Refractory Ventricular Tachycardia With Radiofrequency Ablation And Temporary Mechanical Circulatory Support, Som P. Singh, Alejandro Vidal Margenat, David L. Boone, Ellen Condoure, Ramesh Hariharan

The VAD Journal

Catheter-based radiofrequency ablation has long been recognized as an effective treatment for refractory ventricular tachycardia (VT). A 57-year-old male with severe coronary artery disease underwent percutaneous mechanical circulatory support because of worsening cardiogenic shock after failed revascularization attempts. Despite aggressive medical management, the patient experienced refractory VT episodes, leading to the decision to proceed with radiofrequency catheter ablation. Notably, the Impella 5.5 device (Abiomed) provided critical left ventricular support during the ablation procedure. This case underscores the potential benefits of Impella support during radiofrequency ablation of complex ventricular arrhythmias.


Perceptions Of Diversity, Equity, And Inclusion Within Undergraduate Curriculum And University: A Qualitative Study, Suzanne Grossman, Raihan Khan, Theresa Enyeart Smith Nov 2023

Perceptions Of Diversity, Equity, And Inclusion Within Undergraduate Curriculum And University: A Qualitative Study, Suzanne Grossman, Raihan Khan, Theresa Enyeart Smith

Department of Health Sciences - Faculty Scholarship

Objective

Diversity, equity, and inclusion (DEI) efforts are important at university campuses, especially preparing students for the workforce. This study aimed to identify perceptions of DEI among seniors related to their major curriculum and at the university.

Participants

In Spring 2021, 101 graduating seniors, who are future health professionals, completed an online survey.

Methods

Open-ended and multiple-choice survey items were analyzed. Thematic coding for open-ended questions and SPSS was used for the quantitative analysis.

Results

Analyses revealed the university kept students informed of DEI activities; however, more could be done. In the department, participants reported that classes focused on DEI …


A Tale Of Two Targets: Examining The Differential Effects Of Posterior Cingulate Cortex- And Amygdala-Targeted Fmri-Neurofeedback In A Ptsd Pilot Study, Jonathan M. Lieberman, Daniela Rabellino, Maria Densmore, Paul Frewen, David Steyrl, Frank Scharnowski, Jean Theberge, Niki Hosseini-Kamkar, Richard W.J. Neufeld, Rakesh Jetly, Benicio N. Frey, Tomas Ros, Ruth A. Lanius, Andrew A. Nicholson Nov 2023

A Tale Of Two Targets: Examining The Differential Effects Of Posterior Cingulate Cortex- And Amygdala-Targeted Fmri-Neurofeedback In A Ptsd Pilot Study, Jonathan M. Lieberman, Daniela Rabellino, Maria Densmore, Paul Frewen, David Steyrl, Frank Scharnowski, Jean Theberge, Niki Hosseini-Kamkar, Richard W.J. Neufeld, Rakesh Jetly, Benicio N. Frey, Tomas Ros, Ruth A. Lanius, Andrew A. Nicholson

Department of Medicine Publications

Introduction: Real-time fMRI-based neurofeedback (rt-fMRI-NFB) is a non-invasive technology that enables individuals to self-regulate brain activity linked to neuropsychiatric symptoms, including those associated with post-traumatic stress disorder (PTSD). Selecting the target brain region for neurofeedback-mediated regulation is primarily informed by the neurobiological characteristics of the participant population. There is a strong link between PTSD symptoms and multiple functional disruptions in the brain, including hyperactivity within both the amygdala and posterior cingulate cortex (PCC) during trauma-related processing. As such, previous rt-fMRI-NFB studies have focused on these two target regions when training individuals with PTSD to regulate neural activity. However, the differential …


Vaccination Status, Views, And Opinions On The Covid-19 Vaccine, Zuri Dale Nov 2023

Vaccination Status, Views, And Opinions On The Covid-19 Vaccine, Zuri Dale

COVID Research

The Spring 2023 Tigers Care Vaccination Status and Views/Opinion Survey sought to capture perspectives on COVID-19 vaccination within the Texas Southern University community during spring festivities, engaging 126 respondents. Findings revealed that 86.29% were fully vaccinated, predominantly with the Pfizer vaccine. Among respondents, 78% had received a booster, and 42% expressed willingness to get a new booster in 2023.

Hesitancy was reported by 40% of participants, driven by concerns about long-term effects and vaccine safety. Factors like medical consultations and research helped change minds among hesitant individuals. A small segment (9.68%) remained unvaccinated, largely citing personal choice or distrust in …


Towards Digital Health Transformation: The Urgency Of Electronic Student Health Reports (Case Study In Sd Negeri Cipedak 03, South Jakarta And Puskesmas Jagakarsa), Retnowati Retnowati, Kemal N. Siregar, Dion Zein Nurizin, Arief Azhari Ilyas Nov 2023

Towards Digital Health Transformation: The Urgency Of Electronic Student Health Reports (Case Study In Sd Negeri Cipedak 03, South Jakarta And Puskesmas Jagakarsa), Retnowati Retnowati, Kemal N. Siregar, Dion Zein Nurizin, Arief Azhari Ilyas

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

The community health center (Puskesmas) routinely collects student health examination data in health report books, causing storage, monitoring, and analysis difficulties. This has led to suboptimal health interventions involving parents, schools, and Puskesmas. This research analyzes user needs in developing an electronic-based student health report. This qualitative descriptive study employs the Framework for the Application of System Thinking (FAST) approach. The research was conducted at the Puskesmas Jagakarsa and SD Negeri Cipedak 03, South Jakarta. The study findings indicate utilizing student health report books is not optimal. Based on the needs analysis, there is a necessity to develop an electronic-based …


Analisis Spasial Autokorelasi Tuberkulosis Di Pulau Jawa Tahun 2021, Nayaka Nayottama Pamadi, Kemal N. Siregar, Martya Rahmaniati, Atmiroseva Atmiroseva Nov 2023

Analisis Spasial Autokorelasi Tuberkulosis Di Pulau Jawa Tahun 2021, Nayaka Nayottama Pamadi, Kemal N. Siregar, Martya Rahmaniati, Atmiroseva Atmiroseva

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Tuberkulosis (TB) adalah salah satu penyakit menular yang masih menjadi masalah kesehatan masyarakat di Indonesia. Terlebih, adanya pandemi COVID-19 berimbas kepada berkurangnya progress dan penanganan TB di tahun 2021, maka dari itu dilakukan penelitian untuk mengetahui situasi TB dan melihat hubungan spasial pada kasus TB dengan faktor-faktor risikonya di salah satu wilayah dengan jumlah kasus tertinggi di Indonesia; Pulau Jawa, di tingkat kabupaten/kota. Faktor risiko dibagi menjadi dua kelompok, yaitu faktor geografis seperti rata-rata ketinggian, suhu tahunan, dan kelembaban tahunan; serta faktor sosiodemografi yang mencakup kepadatan penduduk/densitas, jumlah fasilitas kesehatan, dan rata-rata usia diagnosis. Hasil penelitian menunjukkan adanya pola mengelompok …


Hnrnpa1 Sumoylation Promotes Cold Hypersensitivity In Chronic Inflammatory Pain By Stabilizing Trpa1 Mrna, Qiao Zhang, Weiji Weng, Xiaokun Gu, Jinhua Xiang, Yang Yang, Michael X Zhu, Weidong Gu, Zhenzhou He, Yong Li Nov 2023

Hnrnpa1 Sumoylation Promotes Cold Hypersensitivity In Chronic Inflammatory Pain By Stabilizing Trpa1 Mrna, Qiao Zhang, Weiji Weng, Xiaokun Gu, Jinhua Xiang, Yang Yang, Michael X Zhu, Weidong Gu, Zhenzhou He, Yong Li

Faculty, Staff and Student Publications

TRPA1 is pivotal in cold hypersensitivity, but its regulatory mechanisms in inflammatory cold hyperalgesia remain poorly understood. We show here that the upregulation of SUMO1-conjugated protein levels in a complete Freund's adjuvant (CFA)-induced inflammatory pain model enhances TRPA1 mRNA stability, ultimately leading to increased expression levels. We further demonstrate that hnRNPA1 binds to TRPA1 mRNA, and its SUMOylation, upregulated in CFA-induced inflammatory pain, contributes to stabilizing TRPA1 mRNA by accumulating hnRNPA1 in the cytoplasm. Moreover, we find that wild-type hnRNPA1 viral infection in dorsal root ganglia neurons, and not infection with the SUMOylation-deficient hnRNPA1 mutant, can rescue the reduced ability …


Workplace Violence In Emergency Departments, Education And De-Escalation Training: A Benchmark Study, Summer Block Nov 2023

Workplace Violence In Emergency Departments, Education And De-Escalation Training: A Benchmark Study, Summer Block

MSN Capstone Projects

Most people do not go to work and fear being assaulted or harassed daily. However, for emergency nurses in this county that is exactly what it has come to. Up to 96% of emergency department nurses state they have been verbally abused. This entails name calling, verbal threats, being shouted at and being sworn at. Anywhere from 25% to 60% of these nurses have had to face physical assaults while on the job. (Al-Aadi, 2020; Copeland & Henry, 2017; Grinberg, 2022; Li et al., 2019; McDermid et al., 2019). Physical assaults can include being spit on, slapped, punched, kicked, choked, …


Pemodelan Statistik Hubungan Pemenuhan Standar Pelayanan Kesehatan Ibu Dengan Penggunaan Metode Kb Pascapersalinan Di Nusa Tenggara Timur, Sulawesi Barat, Maluku, Nurrachda Hanafi, Martya Rahmaniati, Kemal N. Siregar, Lilik Aryani Falupi Nov 2023

Pemodelan Statistik Hubungan Pemenuhan Standar Pelayanan Kesehatan Ibu Dengan Penggunaan Metode Kb Pascapersalinan Di Nusa Tenggara Timur, Sulawesi Barat, Maluku, Nurrachda Hanafi, Martya Rahmaniati, Kemal N. Siregar, Lilik Aryani Falupi

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Penelitian ini membahas pemenuhan standar pelayanan Kesehatan ibu terhadap penggunaan metode KB Pascapersalinan dengan tujuan mengetahui hubungan antara pemenuhan standar pelayanan Kesehatan ibu terhadap penggunaan metode KB pascapersalinan di NTT, Sulawesi Barat, Maluku. Desain studi cross-sectional dengan analisis multivariabel regresi logistik menggunakan data sekunder SDKI 2017. Jumlah sampel yang digunakan sebesar 404 sampel dengan rincian NTT (151), Sulawesi Barat (115), Maluku (138) pada WUS yang pernah melahirkan anak hidup dalam periode satu tahun terakhir dan menggunakan metode KB pascapersalinan periode 42 hari setelah melahirkan. Proporsi penggunaan metode KB pascapersalinan di NTT 32,5%, Sulawesi Barat 33% dan Maluku 39,9%. Hasil penelitian …


Hubungan Akses Layanan Kesehatan Dengan Penggunaan Metode Kontrasepsi Jangka Panjang Di Indonesia: Analisis Data Skap Kkbpk 2019, Vallery Violila, Tris Eryando, Kemal N. Siregar, Lilik Aryani Falupi Nov 2023

Hubungan Akses Layanan Kesehatan Dengan Penggunaan Metode Kontrasepsi Jangka Panjang Di Indonesia: Analisis Data Skap Kkbpk 2019, Vallery Violila, Tris Eryando, Kemal N. Siregar, Lilik Aryani Falupi

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Program KB di Indonesia khususnya penggunaan MKJP menjadi upaya pemerintah dalam mengendalikan penduduk, khususnya pada kelompok berisiko. Namun, penggunaan mix-method MKJP di Indonesia relatif masih rendah, yaitu 24,6% dibandingkan negara ASEAN lainnya. Wanita menikah di Indonesia masih mengalami masalah dalam mengakses layanan kesehatan seperti masih tingginya angka unmet-need serta rendahnya presentase wanita terpapar informasi dari penyuluh lapangan KB dan informed choice KB. Penelitian ini bertujuan untuk mengidentifikasi indikator akses layanan kesehatan dan mengetahui hubungan akses layanan kesehatan dengan penggunaan MKJP. Penelitian ini menggunakan data SKAP KKBPK 2019 dengan desain penelitian cross-sectional. Analisis univariat dilakukan untuk mengidentifikasi indikator akses layanan …


Maternal Age Extremes And Adverse Pregnancy Outcomes In Low-Resourced Settings, Paul Nyongesa, Osayame Ekhaguere, Irene Marete, Constance Tenge, Milsort Kemoi, Carla Bann, Sherri Bucher, Archana Patel, Patricia Hibberd, Farnaz Naqvi, Sarah Saleem, Robert Goldenberg, Shivaprasad Goudar, Richard Derman, Nancy Krebs, Ana Garces, Elwyn Chomba, Waldemar Carlo, Musaku Mwenechanya, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Marion Koso-Thomas, Janet Moore, Elizabeth Mcclure, Edward Liechty, Fabian Esamai Nov 2023

Maternal Age Extremes And Adverse Pregnancy Outcomes In Low-Resourced Settings, Paul Nyongesa, Osayame Ekhaguere, Irene Marete, Constance Tenge, Milsort Kemoi, Carla Bann, Sherri Bucher, Archana Patel, Patricia Hibberd, Farnaz Naqvi, Sarah Saleem, Robert Goldenberg, Shivaprasad Goudar, Richard Derman, Nancy Krebs, Ana Garces, Elwyn Chomba, Waldemar Carlo, Musaku Mwenechanya, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Marion Koso-Thomas, Janet Moore, Elizabeth Mcclure, Edward Liechty, Fabian Esamai

Global Health Articles

INTRODUCTION: Adolescent (years) and advanced maternal age (>35 years) pregnancies carry adverse risks and warrant a critical review in low- and middle-income countries where the burden of adverse pregnancy outcomes is highest.

OBJECTIVE: To describe the prevalence and adverse pregnancy (maternal, perinatal, and neonatal) outcomes associated with extremes of maternal age across six countries.

PATIENTS AND METHODS: We performed a historical cohort analysis on prospectively collected data from a population-based cohort study conducted in the Democratic Republic of Congo, Guatemala, India, Kenya, Pakistan, and Zambia between 2010 and 2020. We included pregnant women and their neonates. We describe the …


Evidence-Supported Interventions For Reducing Secondary Stroke Risk In Sub-Saharan Africa: A Systematic Review, Alyssa M. Edwards, Christopher J. Burant, Shirley M. Moore, Carol Blixen, Maratha Sajatovic Nov 2023

Evidence-Supported Interventions For Reducing Secondary Stroke Risk In Sub-Saharan Africa: A Systematic Review, Alyssa M. Edwards, Christopher J. Burant, Shirley M. Moore, Carol Blixen, Maratha Sajatovic

Faculty Scholarship

The study set out to perform a systematic literature review of evidence-based interventions that target the reduction of secondary stroke risk in Africa. The review analyzed longitudinal intervention studies conducted in Sub-Saharan Africa, focusing on adult participants who had suffered a prior stroke. It encompassed publications and peer-reviewed papers sourced from reputable databases, including PubMed, Ovid, Cochrane, and Web of Science. Three randomized clinical trial (RCT) studies were included with sample sizes ranging from 16 to 400 participants, mean age ranged between 50 and 66 years, with 64.5% male participants. All studies applied multidisciplinary team interventions of enhanced patient follow-up …


Preliminary Content And Construct Validity Of A New Model To Differentiate Research Skills From Evidence‐Based Practice Skills: Core, Evidence Application, Research (Cear) Model, Raeanne Jordan, Rosanna P. Watowicz, Catherine Phillips, Rita Obeid, Rosa K. Hand Nov 2023

Preliminary Content And Construct Validity Of A New Model To Differentiate Research Skills From Evidence‐Based Practice Skills: Core, Evidence Application, Research (Cear) Model, Raeanne Jordan, Rosanna P. Watowicz, Catherine Phillips, Rita Obeid, Rosa K. Hand

Faculty Scholarship

Background: Research is the scientific basis for the profession of dietetics, as it must be located and applied in evidence‐based practice (EBP). EBP is often presented as a foundational skill for research. CEAR – Core, Evidence Application, Research – is a newly proposed model that separates Research and Evidence Application skills into distinct domains, jointly supported by a set of Core skills, thus acknowledging that education and advancement in one domain neither requires nor precipitates education and advancement in the other. The goal was to investigate the content and construct validity of the new CEAR Model. Methods: A cross‐sectional online …


Data-Driven Multiscale Model Of Macaque Auditory Thalamocortical Circuits Reproduces In Vivo Dynamics, Salvador Dura-Bernal, Erica Y Griffith, Annamaria Barczak, Monica N O'Connell, Tammy Mcginnis, Joao V S Moreira, Charles E Schroeder, William W Lytton, Peter Lakatos, Samuel A Neymotin Nov 2023

Data-Driven Multiscale Model Of Macaque Auditory Thalamocortical Circuits Reproduces In Vivo Dynamics, Salvador Dura-Bernal, Erica Y Griffith, Annamaria Barczak, Monica N O'Connell, Tammy Mcginnis, Joao V S Moreira, Charles E Schroeder, William W Lytton, Peter Lakatos, Samuel A Neymotin

Faculty, Staff and Student Publications

We developed a detailed model of macaque auditory thalamocortical circuits, including primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus, utilizing the NEURON simulator and NetPyNE tool. The A1 model simulates a cortical column with over 12,000 neurons and 25 million synapses, incorporating data on cell-type-specific neuron densities, morphology, and connectivity across six cortical layers. It is reciprocally connected to the MGB thalamus, which includes interneurons and core and matrix-layer-specific projections to A1. The model simulates multiscale measures, including physiological firing rates, local field potentials (LFPs), current source densities (CSDs), and electroencephalography (EEG) signals. Laminar CSD patterns, …