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2023

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Articles 18211 - 18240 of 27453

Full-Text Articles in Medicine and Health Sciences

Influence Of Different Conditioning Protocols On Bond Strength To Glass Ceramic, Fatima A. Shalaby, Nesma M. Elgohary, Noha A. El Wassefy, Ahmed A. Abo El- Naga Mar 2023

Influence Of Different Conditioning Protocols On Bond Strength To Glass Ceramic, Fatima A. Shalaby, Nesma M. Elgohary, Noha A. El Wassefy, Ahmed A. Abo El- Naga

Mansoura Journal of Dentistry

Objective: To detect the effect of different surface treatments on bond strength to machinable glass ceramic. Materialsand Methods: Sixteen glass ceramic blocks (IPS e.max CAD/CAM) were fabricated by a CAD/CAM machine withdimensions (6mm × 11mm x 13mm) and divided into 4 groups (n=4), according to surface treatments: (G1)Hydrofluoric acid (HF) etching and silane application, (G2) Acidulated phosphate fluoride (APF) and silaneapplication, (G3) Monobond Etch and Prime (MEP), (G4) Tetrabutylammonium dihydrogen trifluoride (TDTF) andsilane application.Composite resin blocks (Te econome) were fabricated and cemented to the treated ceramic blocksusing adhesive resin cement. All bonded specimens were kept in a water bath for …


Creating The Capacity For Digital Government, Cheow Hoe Chan, Steven M. Miller Mar 2023

Creating The Capacity For Digital Government, Cheow Hoe Chan, Steven M. Miller

Asian Management Insights

This article explains how a well-thought-out data policy, supported by a tech stack and cloud infrastructure, an agile way of working, and coordinated whole-of-government leadership, are fundamental to successful government digital transformation efforts, as exemplified by the Singapore government’s digital journey. As part of explaining how to create the capacity for digital government, the main sections of this article cover:

  • The origins of GovTech
  • How thinking big, starting small and acting fast is a practical strategy for organisational learning
  • The importance of horizontal platforms and other enablers of a horizontal approach
  • Data architecture and policy
  • “Shifting left” with internal technology …


Making Morbidity Multiple: History, Legacies, And Possibilities For Global Health, Justin Dixon, Emily Mendenhall, Edna Bosire, Felix Limbani, Rashida A. Ferrand, Clare I R. Chandler Mar 2023

Making Morbidity Multiple: History, Legacies, And Possibilities For Global Health, Justin Dixon, Emily Mendenhall, Edna Bosire, Felix Limbani, Rashida A. Ferrand, Clare I R. Chandler

Brain and Mind Institute

Multimorbidity has been framed as a pressing global health challenge that exposes the limits of systems organised around single diseases. This article seeks to expand and strengthen current thinking around multimorbidity by analysing its construction within the field of global health. We suggest that the significance of multimorbidity lies not only in challenging divisions between disease categories but also in what it reveals about the culture and history of transnational biomedicine. Drawing on social research from sub-Saharan Africa to ground our arguments, we begin by describing the historical processes through which morbidity was made divisible in biomedicine and how the …


Long-Term Safety And Efficacy Of Non-Absorbable Abdominal Mesh For Apical Prolapse Surgery: A 10-Year Experience At Tertiary Care Hospital, Samia Aijaz, Novera G. Chughtai, Urooj Kashif, Summera Malik Mar 2023

Long-Term Safety And Efficacy Of Non-Absorbable Abdominal Mesh For Apical Prolapse Surgery: A 10-Year Experience At Tertiary Care Hospital, Samia Aijaz, Novera G. Chughtai, Urooj Kashif, Summera Malik

Department of Obstetrics & Gynaecology

Objectives: To evaluate the complications of apical prolapse correction with abdominally placed mesh and to assess the long-term efficacy of Sacrohysteropexy and Sacrocolpopexy.
Method: A retrospective cohort study was conducted at the Department of Gynecology and Obstetrics, Aga Khan University Hospital. All women who underwent apical prolapse surgery using abdominal mesh from January 2010 to December 2019 at AKUH were included. Patients with missing routine follow up visits and incomplete data up to one year post op were excluded. Patient notes were reviewed, and subjective and objective success and complications were analyzed. Safety was measured by incidence of intra, early …


Medical Device-Related Pressure Injury (Mdrpi) Prevention In The Intensive Care Unit (Icu): An Evidence Based Practice Quality Improvement Project, Sana Shah Mar 2023

Medical Device-Related Pressure Injury (Mdrpi) Prevention In The Intensive Care Unit (Icu): An Evidence Based Practice Quality Improvement Project, Sana Shah

DNP Projects

Introduction: All intensive care unit (ICU) patients utilize various medical devices for care and treatment, placing them at high-risk for medical device-related pressure injuries (MDRPIs), which can lead to life-threatening infections, wounds/scars, and consumption of additional time and products to rectify these issues. Lack of appropriate decompression measures and improper bedside handoff report was recognized in the ICU at a hospital in Connecticut (CT).

Method: A literature search using CINAHL, MEDLINE, and the Cochrane Database of Systematic Reviews was conducted, restricting the search to the period between 2018-2022. The keywords searched were: “pressure injuries,” “adult patients,” “intensive care …


Faculty Readiness And Learning Needs For Incorporating Virtual Healthcare Into The Curriculum, Kelley Connor, Jason Blomquist, Darci Mccall, Cara Gallegos, Janet Reis Mar 2023

Faculty Readiness And Learning Needs For Incorporating Virtual Healthcare Into The Curriculum, Kelley Connor, Jason Blomquist, Darci Mccall, Cara Gallegos, Janet Reis

Nursing Faculty Publications and Presentations

Objective: Virtual healthcare technologies are becoming increasingly acceptable and available to patients and providers to deliver care. Although common in practice settings, many nursing schools have not integrated virtual care concepts into the curriculum. One reason may be because faculty are not prepared to teach these concepts. The purpose of this study was to assess the virtual healthcare learning needs of faculty.

Methods: An exploratory, descriptive study design was used to evaluate faculty receptiveness and readiness to teach virtual nursing care concepts. Thirty-seven full time faculty members were asked to complete an anonymous survey consisting of demographic, open-ended, and Likert …


Dredged Sediments Contain Potentially Beneficial Microorganisms For Agriculture And Little Harmful Cyanobacteria, Megan A. Rúa, Ashley N. Julian, Louise Stevenson Mar 2023

Dredged Sediments Contain Potentially Beneficial Microorganisms For Agriculture And Little Harmful Cyanobacteria, Megan A. Rúa, Ashley N. Julian, Louise Stevenson

Biological Sciences Faculty Publications

Abstract Introduction Soils worldwide are degrading, raising concerns about our ability to feed the growing global population. Soil amendments that can alleviate degradation are gaining attention. The application of sediments dredged from waterways to agricultural fields has increasing promise as a means for improving degraded soils. However, herbaceous plant species may have difficulty establishing on dredged material because of low nutrient availability, inhibitory levels of toxins, unsuitable moisture conditions and lack of microorganisms capable of ameliorating these characteristics. To counteract these issues, we sought to understand if the use of a cover crop would increase the abundance, diversity and function …


Logic Model And Data System Recommendations, Claire Devine, Natalie Royal Kenton, Kristen Lacijan, Maggie Weller Mar 2023

Logic Model And Data System Recommendations, Claire Devine, Natalie Royal Kenton, Kristen Lacijan, Maggie Weller

Articles, Abstracts, and Reports

No abstract provided.


Evaluating The Impact Of Long Read Genomes In Rare Disease: A Systematic Analysis Of 1000 Hifi Genomes, Emily Farrow, Isabelle Thiffault, Ana S A Cohen, Tricia N. Zion, Adam Walter, Margaret Gibson, Chengpeng Bi, Warren A. Cheung, Jeffrey J. Johnston, T Pastinen Mar 2023

Evaluating The Impact Of Long Read Genomes In Rare Disease: A Systematic Analysis Of 1000 Hifi Genomes, Emily Farrow, Isabelle Thiffault, Ana S A Cohen, Tricia N. Zion, Adam Walter, Margaret Gibson, Chengpeng Bi, Warren A. Cheung, Jeffrey J. Johnston, T Pastinen

Posters

Introduction: Genomic technologies continue to advance at a rapid rate, leading to continued novel gene-disease discoveries. However, despite the exponential increase in new gene discoveries, diagnostic rates in rare disease continue to range from 30-50%. To evaluate the impact of long read genome sequencing (lrGS) in a rare disease cohort, lrGS was implemented systematically in an institution-wide research program, Genomic Answers for Kids (GA4K). Methods: Individuals enrolled in GA4K, with a suspected genetic disorder, that remained undiagnosed after exome or genome sequencing, were submitted for HiFi sequencing. Probands were sequenced to a target depth of 30X coverage. Analyses included copy …


If We Know Better, Why Don’T We Do Better? A Qi Project Aimed At Addressing Pain Related To Vaccinations, Haley J. Killian, Amanda D. Deacy, Elizabeth Edmundson, Lucy Raab, Jennifer Verrill Schurman Mar 2023

If We Know Better, Why Don’T We Do Better? A Qi Project Aimed At Addressing Pain Related To Vaccinations, Haley J. Killian, Amanda D. Deacy, Elizabeth Edmundson, Lucy Raab, Jennifer Verrill Schurman

Posters

Introduction: Evidenced-based tools have long existed to combat pain and anxiety associated with needle sticks, yet the gap between knowledge and uptake persists. Prior to COVID-19, our institution initiated a quality improvement (QI) program to improve comfort measure (CM) uptake, beginning with specific clinical areas with intent to scale up over time. When the COVID-19 vaccine was approved, mass vaccination clinics provided an opportunity to rapidly improve CM uptake across the institution. Methods: Mass vaccination clinics were staffed by nurses from across the hospital. Clinics occurred in 3 waves, based on federal approval for age groups (1: 12y+, 2: 5-11y, …


The Policy Environment Of Self-Care: A Case Study Of The Philippines, Leonardo Jaminola Iii, Jana Marie Negre, Veincent Christian F. Pepito, Arianna Maever Loreche, Manuel M. Dayrit Mar 2023

The Policy Environment Of Self-Care: A Case Study Of The Philippines, Leonardo Jaminola Iii, Jana Marie Negre, Veincent Christian F. Pepito, Arianna Maever Loreche, Manuel M. Dayrit

Ateneo School of Medicine and Public Health Publications

Self-care is the ability and empowerment of individuals to maintain health through informed health-care decisions, with or without the support of a health provider. High-income countries have made advances to their conceptualization, research and institutionalization of self-care, given its reported benefits to patients, the health system and economy. A similar undertaking in low- and middle-income countries (LMICs) with already fragile health systems is warranted as highlighted by the coronavirus disease 2019 pandemic. Our article therefore aimed to describe and analyse the policy environment of self-care using the Philippines as a case study, which may have relevance to other similar countries …


Using A Mobile Food Pantry To Address The Food Insecurity Needs Of College Students, Madison Lapke, Barbara Stoecker, M. Craig Edwards, Janice Hermann Mar 2023

Using A Mobile Food Pantry To Address The Food Insecurity Needs Of College Students, Madison Lapke, Barbara Stoecker, M. Craig Edwards, Janice Hermann

Journal of Human Sciences and Extension

Food insecurity is a prevalent issue throughout the United States, the state of Oklahoma, and on Oklahoma State University’s (OSU) Stillwater campus. Research has shown that college and university students tend to be more food insecure than national population averages and Stillwater’s food insecurity rates have been even higher. Mobile food pantries (MFP) generally have been effective in addressing food insecurity, but few studies have investigated their use to alleviate food insecurity among college students. Our Daily Bread Food and Resource Center (ODB) in Stillwater implemented an MFP on OSU’s campus. The present study surveyed students who utilized the MFP …


Factors Associated With Fathers’ Attendance In A Latino Family Obesity Prevention Program, Sayaka Nagao-Sato, Silvia Alvarez De Davila, Aysegul Baltaci, Roxana Linares, Alejandro Omar Peralta Reyes, Youjie Zhang, Ghaffar Hurtado Choque, Marla Reicks Mar 2023

Factors Associated With Fathers’ Attendance In A Latino Family Obesity Prevention Program, Sayaka Nagao-Sato, Silvia Alvarez De Davila, Aysegul Baltaci, Roxana Linares, Alejandro Omar Peralta Reyes, Youjie Zhang, Ghaffar Hurtado Choque, Marla Reicks

Journal of Human Sciences and Extension

Community-based programs may contribute to Latino pediatric obesity prevention; however, attendance remains low. This study aimed to identify factors associated with Latino father/male caregiver attendance in family-based adolescent obesity prevention programs conducted as part of a randomized controlled trial. The study used cross-sectional data from 137 fathers in the program, involving eight weekly sessions to improve their children’s energy balance-related behaviors. Evaluation data were collected at baseline and post-intervention. Fathers in a waitlisted control group attended sessions after post-intervention data collection. Attendance patterns were identified using cluster analysis: consistently high attendance (50% of fathers), declining attendance (19%), and non-attendance (31%) …


Optimizing Npo Times In Infant Outpatient Surgical Patients, Julie Colangelo Ward Mar 2023

Optimizing Npo Times In Infant Outpatient Surgical Patients, Julie Colangelo Ward

DNP Projects

Background: All patients are standardly kept NPO prior to surgery to minimize aspiration risks. Increased NPO times for infants has been found to lead to patient distress, hemodynamic instability, ketoacidosis and acid-base imbalances. Optimizing NPO times for young pediatric patients helps to decrease fasting times, which minimizes the safety concerns listed above.

Objectives: The objective of this project was to implement specific education instructions to parents of infants during the pre-operative phone calls and confirm their understanding of this education through the teach-back method.

Methods: The intervention for this project added educational instructions with a teach-back question into the verbal …


Rewarding Relationships: A Quasi-Experimental Design Evaluating The Impact Of An Extension Public Relations Seminar, Ashley Mcleod-Morin, Lauri M. Baker, Cheryl Boyer, Anissa M. Zagonel, Angela B. Lindsey Mar 2023

Rewarding Relationships: A Quasi-Experimental Design Evaluating The Impact Of An Extension Public Relations Seminar, Ashley Mcleod-Morin, Lauri M. Baker, Cheryl Boyer, Anissa M. Zagonel, Angela B. Lindsey

Journal of Human Sciences and Extension

While Extension communication units have seen success in implementing brand strategies to raise awareness of Extension, the public value and need for Extension programming continue to be misunderstood. College students have the potential to ensure the future of Extension is viable. To expose undergraduate students to the brand and value of Extension, a public relations seminar was developed and delivered by a state Extension specialist to 95 students enrolled in an agricultural technical writing course at a land-grant university. The seminar served as a treatment in the quasi-experimental design, which included information about the land-grant mission, Extension resources, and potential …


Health Disparities Experienced By Hispanic Americans With Multiple Myeloma: A Systematic Review, Andrea Anampa-Guzmán, Sara Taveras Alam, Inas Abuali, Samer Al Hadidi Mar 2023

Health Disparities Experienced By Hispanic Americans With Multiple Myeloma: A Systematic Review, Andrea Anampa-Guzmán, Sara Taveras Alam, Inas Abuali, Samer Al Hadidi

Faculty, Staff and Student Publications

Health disparities in multiple myeloma (MM) disproportionately affect minorities. Characterization of health disparities encountered by Hispanic Americans with MM is necessary to identify gaps and inform future strategies to eliminate them. We performed a systematic review of publications that described health disparities relevant to Hispanic Americans with MM through December 2021. We included all original studies which compared incidence, treatment, and/or outcomes of Hispanic Americans with other ethnic groups. Eight hundred and sixty-eight articles were identified of which 22 original study articles were included in our systematic review. The number of publications varied over time with the highest number of …


Predictors Of Early Heart Failure Rehospitalization Among Older Adults With Preserved And Reduced Ejection Fraction: A Review And Derivation Of A Conceptual Model, Carolyn B. Sue-Ling Phd, Rn, Mpa, Nalini Jairath Mar 2023

Predictors Of Early Heart Failure Rehospitalization Among Older Adults With Preserved And Reduced Ejection Fraction: A Review And Derivation Of A Conceptual Model, Carolyn B. Sue-Ling Phd, Rn, Mpa, Nalini Jairath

Publications

BACKGROUND: Heart failure (HF) is prevalent among older adults who suffer with either heart failure preserved ejection fraction (HFpEF) or heart failure reduced ejection fraction (HFrEF) and have a high rate of early HF rehospitalization. Preventing early rehospitalization is complex because of major differences between the two subtypes of HF as well as inadequate predictive models to identify key contributing factors. OBJECTIVE: To present research addressing relationships between selected clinical, hemodynamic, social factors, and early (≤ 60-day) HF rehospitalization in older adults with HFpEF and HFrEF, derive a conceptual model of predictors of rehospitalization, and understand to what extent the …


Approaches For Optimizing Venous Thromboembolism Prevention In Injured Patients: Findings From The Consensus Conference To Implement Optimal Venous Thromboembolism Prophylaxis In Trauma, Amanda L Teichman, Bryan A Cotton, James Byrne, Navpreet K Dhillon, Allison E Berndtson, Michelle A Price, Tracy J Johns, Eric J Ley, Todd Costantini, Elliott R Haut Mar 2023

Approaches For Optimizing Venous Thromboembolism Prevention In Injured Patients: Findings From The Consensus Conference To Implement Optimal Venous Thromboembolism Prophylaxis In Trauma, Amanda L Teichman, Bryan A Cotton, James Byrne, Navpreet K Dhillon, Allison E Berndtson, Michelle A Price, Tracy J Johns, Eric J Ley, Todd Costantini, Elliott R Haut

Faculty, Staff and Student Publications

Venous thromboembolism (VTE) is a major issue in trauma patients. Without prophylaxis, the rate of deep venous thrombosis approaches 60% and even with chemoprophylaxis may be nearly 30%. Advances in VTE reduction are imperative to reduce the burden of this issue in the trauma population. Novel approaches in VTE prevention may include new medications, dosing regimens, and extending prophylaxis to the postdischarge phase of care. Standard dosing regimens of low-molecular-weight heparin are insufficient in trauma, shifting our focus toward alternative dosing strategies to improve prophylaxis. Mixed data suggest that anti-Xa-guided dosage, weight-based dosing, and thromboelastography are among these potential strategies. …


Ideal Cardiovascular Health, Biomarkers, And Coronary Artery Disease In Persons With Hiv, Pamela S Douglas, Sara Mccallum, Michael T Lu, Triin Umbleja, Kathleen V Fitch, Borek Foldyna, Markella V Zanni, Evelynne S Fulda, Gerald S Bloomfield, Carl J Fichtenbaum, Edgar T Overton, Judith A Aberg, Carlos D Malvestutto, Tricia H Burdo, Roberto C Arduino, Ken S Ho, Michael T Yin, Heather J Ribaudo, Steven K Grinspoon Mar 2023

Ideal Cardiovascular Health, Biomarkers, And Coronary Artery Disease In Persons With Hiv, Pamela S Douglas, Sara Mccallum, Michael T Lu, Triin Umbleja, Kathleen V Fitch, Borek Foldyna, Markella V Zanni, Evelynne S Fulda, Gerald S Bloomfield, Carl J Fichtenbaum, Edgar T Overton, Judith A Aberg, Carlos D Malvestutto, Tricia H Burdo, Roberto C Arduino, Ken S Ho, Michael T Yin, Heather J Ribaudo, Steven K Grinspoon

Faculty, Staff and Student Publications

OBJECTIVE: To investigate relationships between Life's Simple 7 (LS7), an assessment of cardiovascular health (CVH), and coronary plaque among people with HIV (PWH).

DESIGN: Cross-sectional.

METHODS: Coronary computed tomography angiography, immune/inflammatory biomarkers, and characterization of LS7 were collected among a subset of ART-treated PWH enrolled in REPRIEVE, a primary prevention trial. Analyses adjusted for cardiovascular disease risk (ASCVD score).

RESULTS: Median age of the 735 participants was 51(±6) years, 16% female, and median (Q1-Q3) CVD risk was 4.5% (2.6-6.9). Forty percent had poor (≤2 ideal components), 51% had intermediate (three or four ideal components), and only 9% had ideal CVH …


Interprofessional Collaborative Attitudes: Comparing Social Work Learners To Their Medicine And Nursing Peers, Joseph Bartholomew, Marcia Mount French, Hea-Won Kim Mar 2023

Interprofessional Collaborative Attitudes: Comparing Social Work Learners To Their Medicine And Nursing Peers, Joseph Bartholomew, Marcia Mount French, Hea-Won Kim

Florida Public Health Review

Interprofessional learning activities in higher education aim to unite healthcare professionals in their future practice, thus reducing duplication and fragmentation of services. This study uses a social learning perspective to examine advanced practice medicine, nursing, and social work learners’ attitudes toward interprofessional education and collaborative practice activities within their university programs. The authors used a cross-sectional design to administer a questionnaire that included the Interprofessional Attitudes Scale (IPAS) to 151 advanced practice health care learners (internal medicine residents, nurse practitioner students, master’s-level social work students). Findings indicated significant differences in three subsections of the IPAS. Social work learners possessed a …


Checking The Scales: A Psychometric Evaluation Of The Weight Concerns Scale In A Sample Of College-Aged Cisgender Men From The United States, Kyle M. Brasil, Callie E. Mims, Ryon C. Mcdermott, Mary E. Pritchard Mar 2023

Checking The Scales: A Psychometric Evaluation Of The Weight Concerns Scale In A Sample Of College-Aged Cisgender Men From The United States, Kyle M. Brasil, Callie E. Mims, Ryon C. Mcdermott, Mary E. Pritchard

Psychological Sciences Faculty Publications and Presentations

Historically, western societies have considered body image issues to predominantly affect young, White women. While in recent years men’s body image issues have been increasingly highlighted by researchers and the media alike, many instruments currently used to identify clinically significant body image disturbances were developed and validated with samples solely of women and/or girls. One such measure, Killen et al.’s (1994) Weight Concerns Scale (WCS), was initially validated in a sample of adolescent girls. The WCS has yet to be validated in samples of men, despite being used in large national surveys of college men and women (e.g., the Healthy …


Open Posterior Reduction And Stabilization Of Ao Spine C3 Sacral Fractures, Philipp Kobbe, Gregory D. Schroeder, Klaus J. Schnake, Lorin M. Benneker, Mark Lambrechts, Frank Hildebrand, Richard M. Sellei Mar 2023

Open Posterior Reduction And Stabilization Of Ao Spine C3 Sacral Fractures, Philipp Kobbe, Gregory D. Schroeder, Klaus J. Schnake, Lorin M. Benneker, Mark Lambrechts, Frank Hildebrand, Richard M. Sellei

Rothman Institute Papers

AO Spine C3 sacral fractures are defined by separation of the spine including S1 from the pelvic ring and are usually result of a high-energy injury. Besides their high biomechanical instability and high rate of associated neurological impairment, these fractures are often extremely difficult to reduce due to severe bony impaction and dislocation. Additional difficulties in management of these fractures arise from only a thin-layer of soft-tissue coverage overlying the injured area.


Left Bundle Branch Area Pacing From A Femoral Approach In A Patient Without Superior Access, Bishnu Dhakal, Stuart Prenner, Edward Magargee, Danesh Modi, Colin Movsowitz, Robert Schaller Mar 2023

Left Bundle Branch Area Pacing From A Femoral Approach In A Patient Without Superior Access, Bishnu Dhakal, Stuart Prenner, Edward Magargee, Danesh Modi, Colin Movsowitz, Robert Schaller

Division of Cardiology Faculty Papers

Limited venous access and lateral left ventricular scar are impediments to traditional cardiac resynchronization therapy. We present a case where placement of an implantable cardioverter-defibrillator from a femoral approach while using left bundle branch area pacing led to clinical improvement. (Level of Difficulty: Intermediate.)


Outcomes After Transcatheter Aortic Valve Implantation In Patients Excluded From Clinical Trials, Waqas Ullah, Matthew Dimeglio, Muhammad Sana, Hamza Muhammadzai, Kirpal Kochar, Salman Zahid, Arnav Kumar, Erin Michos, Mamas Mamas, David Fischman, Michael Savage, Deepak Bhatt, Pinak Shah Mar 2023

Outcomes After Transcatheter Aortic Valve Implantation In Patients Excluded From Clinical Trials, Waqas Ullah, Matthew Dimeglio, Muhammad Sana, Hamza Muhammadzai, Kirpal Kochar, Salman Zahid, Arnav Kumar, Erin Michos, Mamas Mamas, David Fischman, Michael Savage, Deepak Bhatt, Pinak Shah

Division of Cardiology Faculty Papers

Background: The use of transcatheter aortic valve implantation (TAVI) in patients with aortic valve disease excluded from clinical trials has increased with no large-scale data on its safety. Objectives: The purpose of this study was to assess the trend of utilization and adjusted outcomes of TAVI in clinical trials excluded (CTE) vs clinical trials included TAVI (CTI-TAVI) patients. Methods: We used the National Readmission Database (2015-2019) to identify 15 CTE-TAVI conditions. A propensity score-matched analysis was used to calculate the adjusted odds ratio (aOR) of net adverse clinical events (composite of mortality, stroke, and major bleeding) in patients undergoing CTE-TAVI …


Loss Of Peroxiredoxin Iv Protects Mice From Azoxymethane/Dextran Sulfate Sodium-Induced Colorectal Cancer Development, Pratik Thapa, Hong Jiang, Na Ding, Yanning Hao, Aziza Alshahrani, Eun Young Lee, Junichi Fujii, Qiou Wei Mar 2023

Loss Of Peroxiredoxin Iv Protects Mice From Azoxymethane/Dextran Sulfate Sodium-Induced Colorectal Cancer Development, Pratik Thapa, Hong Jiang, Na Ding, Yanning Hao, Aziza Alshahrani, Eun Young Lee, Junichi Fujii, Qiou Wei

Markey Cancer Center Faculty Publications

Peroxiredoxin IV (Prx4), a typical two-cysteine-containing member of the peroxidase family, functions as an antioxidant to maintain cellular redox homeostasis through the reduction of reactive oxygen species (ROS) via cycles of oxidation–reduction reactions. Under oxidative stress, all Prxs including Prx4 are inactivated as their catalytic cysteines undergo hyperoxidation, and hyperoxidized two-cysteine Prxs can be exclusively repaired and revitalized through the reduction cycle catalyzed by sulfiredoxin (Srx). Previously, we showed that Prx4 is a preferred substrate of Srx, and knockout of Srx in mice leads to resistance to azoxymethane/dextran sulfate sodium (AOM/DSS)-induced colon carcinogenesis. To further understand the significance of the …


Therapeutic Potential Of Low-Level Laser Photobiomodulation On Adjuvant Induced Temporomandibular Joint Arthritis In A Rat Model, Rana El-Qashty, Osama A. Elkashty, Eman Hany Mar 2023

Therapeutic Potential Of Low-Level Laser Photobiomodulation On Adjuvant Induced Temporomandibular Joint Arthritis In A Rat Model, Rana El-Qashty, Osama A. Elkashty, Eman Hany

Mansoura Journal of Dentistry

Objective: To test the efficacy of low-level laser therapy (LLLT) to alleviate temporomandibular TMJ induced arthritisin rats. Materials and methods: Rats were randomly allocated to three groups: group I (sham control), group II(arthritis) where animals were subjected to arthritis induction using complete Freund’s adjuvant followed by LLLT (0j/cm2), and group III (LLLT) where animals were subjected to arthritis induction followed by LLLT (38 j/cm2). One andthree weeks after treatment onset, rats were euthanized and specimens were subjected to histological,histomorphometric, and histochemical analysis. Results: The sham group showed normal histology. The arthritic groupshowed severe changes with surface irregularity, loss of condylar …


Evaluation Of Mara Appliance With Skeletal Anchorage In Early Treatment Of Class Ii Malocclusion, Emad Eddin A. Obaid, Marwa A. Tawfik, Ahmed Hafez Mar 2023

Evaluation Of Mara Appliance With Skeletal Anchorage In Early Treatment Of Class Ii Malocclusion, Emad Eddin A. Obaid, Marwa A. Tawfik, Ahmed Hafez

Mansoura Journal of Dentistry

Objective: To investigate the effects of the fixed functional appliance Mandibular Anterior Repositioning Appliance(MARA) with skeletal anchorage on growing patients with skeletal Class II malocclusion. Materials and Methods:This study was conducted on 10 patients with a mean age of 10.3 years with skeletal Class II malocclusion. Thesepatients were treated simultaneously with the MARA appliance with skeletal anchorage for 16.5 months on average. Allthe patients had the following criteria: skeletal Class II due to mandibular retrusion, overjet more than 4mm, nosystemic diseases, no previous orthodontic treatment, or abnormal habits. Photographs and study casts were obtainedbefore and after treatment. Lateral head films …


Immediate Implant Placement Simultaneously With Ridge Augmentation In The Maxillary Esthetic Region Using Allograft Bone Ring Versus Titanium Mesh Guided Bone Regeneration, Omar M. Khamayseh, Nesma M. Elgohary, Fakhreldin H. Abdel-Rahman, Wael M. Said Ahmed Mar 2023

Immediate Implant Placement Simultaneously With Ridge Augmentation In The Maxillary Esthetic Region Using Allograft Bone Ring Versus Titanium Mesh Guided Bone Regeneration, Omar M. Khamayseh, Nesma M. Elgohary, Fakhreldin H. Abdel-Rahman, Wael M. Said Ahmed

Mansoura Journal of Dentistry

Objective: The present study aimed to assess ridge augmentation with an allograft bone ring versus GBR with titaniummesh, and immediate implant placement (IIP) in the maxillary esthetic zone. Materials and Methods: The 12 patientswith 14 defective sockets were randomly divided into two groups: three females and four males in the control group(Titanium mesh-GBR), and three females and two males in the study group (Allograft bone ring). Patients had postoperativeclinical examinations each day for the first week, then once a month for the next six months. Results: : At 6months post-surgery, all cases in the control group healed well and showed …


Characterization Of Lingual Foramina Using Cone-Beam Computed Tomography, Fatma Elbaz, Fatma Ata, Bassant Mowafy, Jilan Youssef Mar 2023

Characterization Of Lingual Foramina Using Cone-Beam Computed Tomography, Fatma Elbaz, Fatma Ata, Bassant Mowafy, Jilan Youssef

Mansoura Journal of Dentistry

Objective: To assess the location and anatomical character of lingual foramina using CBCT. Materials and Methods:CBCT records of 108 patients were evaluated to detect the presence, location, size, and number of lingual foraminausing axial, and cross sectional images. Results: A total of 463 lingual foramina (representing 100% of all patients)were found. Individuals had between one and eight lingual foraminaon their jaw, with the majority of cases having four(24.1%). Regarding the size; 336 (72.7%) were ≤1 mm and 127 (27.3%) were >1 mm. Regarding the location, only 162(35%) were LLF, while most of the lingual foramina were MLF (65%). Moreover 23 …


Methacrylate Versus Ormocer - Based Composites: Impact Of Preheating On Repair Bond Strength, Aya M. El Said, Asmaa A. Mohamed, Ashraf I. Ali, Salah H. Mahmoud Mar 2023

Methacrylate Versus Ormocer - Based Composites: Impact Of Preheating On Repair Bond Strength, Aya M. El Said, Asmaa A. Mohamed, Ashraf I. Ali, Salah H. Mahmoud

Mansoura Journal of Dentistry

Objective: To evaluate and compare the impact of preheating on the repair bond strength of Methacrylate and Ormocerbased composite. Materials and Methods: A total number of 24 standardized cuboid composite blocks were fabricatedwith the aid of teflon split mold (25×4×4) mm dimensions. Half of these composite blocks were made from a universalnanohybrid methacrylate-based composite and the other half was made from a universal nanohybrid Ormocer based.The top surfaces of all mounted specimens were surface treated with sandblasting, silane coupling agents, and universaladhesive of the same brand of composite. Four cylindrical composite rods (2 mm height, 3 mm internal diameter) werebuilt …