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Full-Text Articles in Medicine and Health Sciences

Serum Levels Of Anticeramide Antibodies, Interleukin-4, And Tumor Necrosis Factor In Newly Diagnosed Egyptian Patients With Leprosy, Eman M. A. El Gayed, Heba A. S. Bazid, Hesham N. Khaled, Hoda A. Bassiouny, Mohammed I. Mostafa Apr 2022

Serum Levels Of Anticeramide Antibodies, Interleukin-4, And Tumor Necrosis Factor In Newly Diagnosed Egyptian Patients With Leprosy, Eman M. A. El Gayed, Heba A. S. Bazid, Hesham N. Khaled, Hoda A. Bassiouny, Mohammed I. Mostafa

Menoufia Medical Journal

Objective The aim was to estimate the serum levels of anticeramide antibodies (ACAs), interleukin-4 (IL-4), and tumor necrosis factor (TNF) in patients with leprosy and their possible role in the anticipation of leprosy complications. Background Leprosy is a disease that primarily involves the peripheral nerves and skin. Nerve damage is concomitant with multibacillary (MB) leprosy, and as ceramide is an element of the myelin sheath, ACAs can be a marker in the nerve destruction evaluation. Cytokine estimation can anticipate inflammation instigated by infections or trauma. The authors aimed to detect the role of serum levels of ACA, IL-4, and TNF-α …


From Isolation To Inclusion: Embracing Local Perspectives In Examining The Treatment Model Of Care For Aboriginal Persons Affected By Tuberculosis Or Leprosy In The Kimberley Region, North Western Australia, Stefanie Jane Oliver Jan 2022

From Isolation To Inclusion: Embracing Local Perspectives In Examining The Treatment Model Of Care For Aboriginal Persons Affected By Tuberculosis Or Leprosy In The Kimberley Region, North Western Australia, Stefanie Jane Oliver

Theses

In the remote Kimberley region of North Western Australia, tuberculosis (TB) and leprosy continue to affect a small number of Aboriginal people, despite historical efforts to eliminate either disease. Treatment, predominantly antibiotic therapy, is a principal therapeutic intervention used to cure TB and leprosy and halt infection transmission. Decisions made around treatment therefore impact not only the individual person affected, but also their families and communities. The well-worn models of Directly Observed Therapy (DOT) and case management are used nationally to assist treatment continuity and completion. Neither model has been substantiated for cultural appropriateness nor for meeting the specific needs …