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Management Of Basal Cell Carcinoma With Excision Followed By Rotation Advancement Flap, Remenda Siregar, Fitri Puspita, Widyaningsih Oentari, Ari Karmila Sari

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Basal cell carcinoma (BCC) is the most common malignant skin tumor and is derived from pluripotent cells in the basal layer of the epidermis. One of the BCC management options is surgery followed by a skin flap to close the wound defect.
Case Illustration: We present a 43-year-old woman with a major complaint of non-healing sores on the left zygomatic region, close to the medial canthus, with frequent episodes of bleeding and itching since one year before admission. The lesion was excised and followed by histopathological examination, which revealed the BCC diagnosis with tumor-free edges. Closure of …

A Case Report Of Advanced Neglected Basal Cell Carcinoma, Loren W. Bennett Od, Mph, Faao

Optometric Clinical Practice

Background: Basal cell carcinoma is the most common skin cancer in humans and is frequently found in the periocular region. It is generally characterized by slow growth with rare metastasis and has an excellent prognosis with current surgical techniques. However, if neglected or inadequately treated it can lead to substantial localized tissue destruction and morbidity.

Case Report: This case presents an advanced basal cell carcinoma involving the left side of the nose and medial eyelids which had been neglected by the patient, causing significant functional disability and cosmetic disfigurement. The tumor was removed with a wide surgical excision which required …

Does Beclin 1 Have A Role In Basal Cell Carcinoma?, Alaa H. Marey, Dania N. Abo Elros, Rehab M. Samaka, Tarek M. Rageh

Menoufia Medical Journal

Objective To evaluate the role of Beclin 1 in basal cell carcinoma (BCC). Background BCC is the most common kind of skin cancer with increased incidence. Autophagy is considered an intracellular homeostatic pathway that is related to cancer and other diseases. Beclin 1 is a specific marker for autophagy. Patients and methods This An Ambidirectional Cohort Study was conducted on 77 cases with BCC and 20 age-matched and sex-matched apparently healthy participants. All sections were immunohistochemical stained for Beclin 1 antibody. Results Significant absolute Beclin 1 cytoplasmic localization in epidermis and dermis of control group was noted, whereas in BCC, …