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Full-Text Articles in Medicine and Health Sciences

Folate As Adjunct Therapy To Ssri/Snri For Major Depressive Disorder: Systematic Review & Meta-Analysis, Rabail Altaf, Irasema Gonzalez, Kimberly Rubino, Eric C. Nemec Sep 2021

Folate As Adjunct Therapy To Ssri/Snri For Major Depressive Disorder: Systematic Review & Meta-Analysis, Rabail Altaf, Irasema Gonzalez, Kimberly Rubino, Eric C. Nemec

Physician Assistant Studies Faculty Publications

Objective: Evaluate depression scores, response, and remission rates in patients with major depression receiving adjunct therapy with folate (L-Methylfolate or folic acid) compared to selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor (SSRI or SNRI) monotherapy.

Methods: Academic Search Premier, CINAHL Complete, Cochrane Database of Systematic Reviews, Medline with Full Text, PsychInfo, PubMed, ClinicalTrials.org, and Google Scholar were searched utilizing specific key words. Identified studies were independently screened for inclusion by two reviewers, were assessed for risk of bias using the Revised Cochrane risk-of-bias tool (RoB2), then meta-analyzed using a random effects model with Review Manager (5.4) software.

Results: The …


The Pa Title: Is A Change The Best Way Forward?, Bettie Coplan, Tami Ritsema, James F Cawley May 2021

The Pa Title: Is A Change The Best Way Forward?, Bettie Coplan, Tami Ritsema, James F Cawley

Physician Assistant Studies Faculty Publications

No abstract provided.


Interweaving Teaching Strategies In Interprofessional Education: A Pilot Study With Graduate Occupational Therapy And Physician Assistant Students, Eric C. Nemec, Lola Halperin, Jaimee Betts Hegge Jan 2021

Interweaving Teaching Strategies In Interprofessional Education: A Pilot Study With Graduate Occupational Therapy And Physician Assistant Students, Eric C. Nemec, Lola Halperin, Jaimee Betts Hegge

Physician Assistant Studies Faculty Publications

The importance of interprofessional education (IPE) has been emphasized by the World Health Organization and is currently required by both the occupational therapy (OT) and physician assistant (PA) education accreditation agencies in the United States. Moreover, a growing body of evidence suggests that IPE fosters learners’ understanding of the roles different disciplines play in healthcare delivery and prepares future health professionals for patient-centered care. Authors designed and implemented an IPE event aimed to foster the following core Interprofessional Education Collaborative (IPEC) competencies among graduate OT and PA students: Values/Ethics for Interprofessional Practice, Roles and Responsibilities, Interprofessional Communication, and Teams and …


Efficacy And Safety Of Once-Daily Vibegron For Treatment Of Overactive Bladder In Patients Aged ≥65 And ≥75 Years: Subpopulation Analysis From The Empowur Randomized, International, Phase Iii Study, Susann Varano, David Staskin, Jeffrey Frankel, Denise Shortino, Rachel Jankowich, Paul N. Mudd Jan 2021

Efficacy And Safety Of Once-Daily Vibegron For Treatment Of Overactive Bladder In Patients Aged ≥65 And ≥75 Years: Subpopulation Analysis From The Empowur Randomized, International, Phase Iii Study, Susann Varano, David Staskin, Jeffrey Frankel, Denise Shortino, Rachel Jankowich, Paul N. Mudd

Physician Assistant Studies Faculty Publications

Background

Overactive bladder (OAB) is common among older adults. The efficacy and safety of vibegron for the treatment of OAB were demonstrated in the international, phase III EMPOWUR trial. This subpopulation analysis from EMPOWUR assessed the efficacy and safety of vibegron in patients aged ≥ 65 and ≥ 75 years.

Methods

In EMPOWUR, patients with OAB were randomly assigned 5:5:4 to receive once-daily vibegron 75 mg, placebo, or tolterodine 4 mg extended release, respectively, once daily for 12 weeks. Coprimary efficacy endpoints were change from baseline at week 12 in average daily number of micturitions and urge urinary incontinence (UUI) …