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Full-Text Articles in Medicine and Health Sciences

Impact Of Stress And Hypertension On The Cerebrovasculature, Nada Elsaid, Ahmed Saied, Heba Kandil, Ahmed Soliman, Fatma Taher, Mohiuddin Hadi, Guruprasad Giridharan, Richard Jennings, Manuel Casanova, Robert Keynton, Ayman El-Baz Dec 2021

Impact Of Stress And Hypertension On The Cerebrovasculature, Nada Elsaid, Ahmed Saied, Heba Kandil, Ahmed Soliman, Fatma Taher, Mohiuddin Hadi, Guruprasad Giridharan, Richard Jennings, Manuel Casanova, Robert Keynton, Ayman El-Baz

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Objectives: Both stress and hypertension (HTN) are considered major health problems that negatively impact the cerebral vasculature. In this article we summarize the possible relationship between stress and HTN. Methods: We conducted a systematic review of the literature using a database search of MEDLINE, PubMed, Scopus, and Web of Science. Results: Psychological stress is known to be an important risk factor for essential hypertension. Acute stress can induce transient elevations of blood pressure in the context of the fight-or-flight response. With increased intensity and duration of a perceived harmful event, the normal physiological response is altered, resulting in a failure …


Acetyl-L-Carnitine Protects Against Lps Induced Depression Via Ppar-Γ Induced Inhibition Of Nf-Κb/Nlrp3 Pathway, Amna Samin, Lina Tariq Al Kury, Muhammad Imran Khan, Shabir Hussain, Abdullah Alattar, Reem Alshaman, Fawad Ali Shah, Muhammad Aamir, Shupeng Li Dec 2021

Acetyl-L-Carnitine Protects Against Lps Induced Depression Via Ppar-Γ Induced Inhibition Of Nf-Κb/Nlrp3 Pathway, Amna Samin, Lina Tariq Al Kury, Muhammad Imran Khan, Shabir Hussain, Abdullah Alattar, Reem Alshaman, Fawad Ali Shah, Muhammad Aamir, Shupeng Li

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Introduction Major depressive disorder (MDD) is a debilitating human health status characterized by mood swings and high suicidal attempts. Several studies have reported the role of neuroinflammation in MMD, yet the efficacy of natural drug substances on neuroinflammation-associated depression needs to be further investigated. The present study demonstrated the neuroprotective effects of Acetyl-L- carnitine (ALC) alone or in combination with caffeic acid phenethyl ester (CAPE) on lipopolysaccharide (LPS) induced neuro-inflammation, depression, and anxiety-like behavior. Material and methods Male Sprague Dawley (SD) rats were used to explore the relative effects of ALC and the mechanistic interplay of the peroxisome proliferator-activated receptors …


Vitamin D Status And Blood Pressure In Children And Adolescents: A Systematic Review Of Observational Studies, Myriam Abboud, Fatme Al Anouti, Dimitrios Papandreou, Rana Rizk, Nadine Mahboub, Suzan Haidar Dec 2021

Vitamin D Status And Blood Pressure In Children And Adolescents: A Systematic Review Of Observational Studies, Myriam Abboud, Fatme Al Anouti, Dimitrios Papandreou, Rana Rizk, Nadine Mahboub, Suzan Haidar

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© 2021, The Author(s). Background: Childhood hypertension is a growing public health problem. Simultaneously, hypovitaminosis D is widespread in this population and could be associated with hypertension. This study systematically reviewed the literature on the relationship between vitamin D status and blood pressure (BP) in children and adolescents. Methods: Following the PRISMA guidelines, PUBMED, MEDLINE, CINAHL, EMBASE, Cochrane Library, and ClinicalTrials.gov and the gray literature without language or time restrictions were searched. We included observational studies, assessed their risk of bias, and extracted data on population characteristics, vitamin D status and BP measurements, and the association between the two variables. …


The Interrelationship And Accumulation Of Cardiometabolic Risk Factors Amongst Young Adults In The United Arab Emirates: The Uae Healthy Future Study, Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, E. Murat Tuzcu, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim Dec 2021

The Interrelationship And Accumulation Of Cardiometabolic Risk Factors Amongst Young Adults In The United Arab Emirates: The Uae Healthy Future Study, Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, E. Murat Tuzcu, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim

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Introduction: Similar to other non-communicable diseases (NCDs), people who develop cardiovascular disease (CVD) typically have more than one risk factor. The clustering of cardiovascular risk factors begins in youth, early adulthood, and middle age. The presence of multiple risk factors simultaneously has been shown to increase the risk for atherosclerosis development in young and middle-aged adults and risk of CVD in middle age. Objective: This study aimed to address the interrelationship of CVD risk factors and their accumulation in a large sample of young adults in the United Arab Emirates (UAE). Methods: Baseline data was drawn from the UAE Healthy …


Effect Of Ketogenic Diet On Quality Of Life In Adults With Chronic Disease: A Systematic Review Of Randomized Controlled Trials, Myriam Abboud, Fatme Alanouti, Evridiki Georgaki, Dimitrios Papandreou Dec 2021

Effect Of Ketogenic Diet On Quality Of Life In Adults With Chronic Disease: A Systematic Review Of Randomized Controlled Trials, Myriam Abboud, Fatme Alanouti, Evridiki Georgaki, Dimitrios Papandreou

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Background: Chronic diseases adversely affect quality of life (QOL). The ketogenic diet (KD) may improve the QOL. Objective: The aim of this systematic review was to summarize the available evidence of randomized controlled trials (RCTs) to establish the effect of KD on the QOL in adults with chronic diseases. Methods: Reporting followed PRISMA guidelines. We included randomized controlled trials (RCTs) conducted on adults with chronic disease including an intervention group that received KD and a control group, and where QOL was reported as outcome. We searched PubMed, APA PsycInfo, EMBASE, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), …


The Effect Of Different Methods To Identify, And Scenarios Used To Address Energy Intake Misestimation On Dietary Patterns Derived By Cluster Analysis, Geraldine Lo Siou, Alianu K. Akawung, Nathan M. Solbak, Kathryn L. Mcdonald, Ala Al Rajabi, Heather K. Whelan, Sharon I. Kirkpatrick Dec 2021

The Effect Of Different Methods To Identify, And Scenarios Used To Address Energy Intake Misestimation On Dietary Patterns Derived By Cluster Analysis, Geraldine Lo Siou, Alianu K. Akawung, Nathan M. Solbak, Kathryn L. Mcdonald, Ala Al Rajabi, Heather K. Whelan, Sharon I. Kirkpatrick

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Background: All self-reported dietary intake data are characterized by measurement error, and validation studies indicate that the estimation of energy intake (EI) is particularly affected. Methods: Using self-reported food frequency and physical activity data from Alberta’s Tomorrow Project participants (n = 9847 men 16,241 women), we compared the revised-Goldberg and the predicted total energy expenditure methods in their ability to identify misreporters of EI. We also compared dietary patterns derived by k-means clustering under different scenarios where misreporters are included in the cluster analysis (Inclusion); excluded prior to completing the cluster analysis (ExBefore); excluded after completing the cluster analysis (ExAfter); …


Accelerometer Measured Physical Activity Patterns Of Children During Segmented School Day In Abu Dhabi, Rahma Ajja, Ludmilla F. Wikkeling-Scott, Keith Brazendale, Rafiq Hijazi, Abdishakur Abdulle Dec 2021

Accelerometer Measured Physical Activity Patterns Of Children During Segmented School Day In Abu Dhabi, Rahma Ajja, Ludmilla F. Wikkeling-Scott, Keith Brazendale, Rafiq Hijazi, Abdishakur Abdulle

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Background: The overwhelming majority of United Arab Emirates (UAE) school-aged children do not meet the 60 min per day recommendation of moderate-to-vigorous physical activity (MVPA). Understanding the different school day segments contribution to children reaching this goal is a crucial step toward developing successful strategies to promote school day MVPA levels. This study aimed to objectively measure children’s’ physical activity levels and to examine the difference in physical activity levels between high active and low active children during the school day in Abu Dhabi. Methods: A total of 133 school children (56% boys; mean age 10.5 years; grades 4–7) from …


Exercise And Nutrition Impact On Osteoporosis And Sarcopenia—The Incidence Of Osteosarcopenia: A Narrative Review, Sousana K. Papadopoulou, Konstantinos Papadimitriou, Gavriela Voulgaridou, Evridiki Georgaki, Eudoxia Tsotidou, Olga Zantidou, Dimitrios Papandreou Dec 2021

Exercise And Nutrition Impact On Osteoporosis And Sarcopenia—The Incidence Of Osteosarcopenia: A Narrative Review, Sousana K. Papadopoulou, Konstantinos Papadimitriou, Gavriela Voulgaridou, Evridiki Georgaki, Eudoxia Tsotidou, Olga Zantidou, Dimitrios Papandreou

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Osteoporosis and sarcopenia are diseases which affect the myoskeletal system and often occur in older adults. They are characterized by low bone density and loss of muscle mass and strength, factors which reduce the quality of life and mobility. Recently, apart from pharmaceutical interventions, many studies have focused on non-pharmaceutical approaches for the prevention of osteoporosis and sarcopenia with exercise and nutrition to being the most important and well studied of those. The purpose of the current narrative review is to describe the role of exercise and nutrition on prevention of osteoporosis and sarcopenia in older adults and to define …


The Dynamics Of Covid-19 In The Uae Based On Fractional Derivative Modeling Using Riesz Wavelets Simulation, Mutaz Mohammad, Alexander Trounev, Carlo Cattani Dec 2021

The Dynamics Of Covid-19 In The Uae Based On Fractional Derivative Modeling Using Riesz Wavelets Simulation, Mutaz Mohammad, Alexander Trounev, Carlo Cattani

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© 2021, The Author(s). The well-known novel virus (COVID-19) is a new strain of coronavirus family, declared by the World Health Organization (WHO) as a dangerous epidemic. More than 3.5 million positive cases and 250 thousand deaths (up to May 5, 2020) caused by COVID-19 and has affected more than 280 countries over the world. Therefore studying the prediction of this virus spreading in further attracts a major public attention. In the Arab Emirates (UAE), up to the same date, there are 14,730 positive cases and 137 deaths according to national authorities. In this work, we study a dynamical model …


Characterizing Individuals Accessing Mental Health Services In The Uae: A Focus On Youth Living In Dubai, Mariapaola Barbato, Shaikha Al Hemeiri, Shorouk Nafie, Baraa A. Dhuhair, Nadia T. Dabbagh Dec 2021

Characterizing Individuals Accessing Mental Health Services In The Uae: A Focus On Youth Living In Dubai, Mariapaola Barbato, Shaikha Al Hemeiri, Shorouk Nafie, Baraa A. Dhuhair, Nadia T. Dabbagh

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Background: Most mental health issues develop during adolescence, therefore identifying youth mental health needs and pathways to care is critical to improve prevention. To date, studies have typically focused on Western samples, while the impact of cultural diversity on perception of health and illness, and pathways to care, remain poorly understood. To address the shortage of studies conducted in the Arab world, and particularly in the United Arab Emirates (UAE), the present investigation aims to identify the characteristics of youth accessing mental health services in Dubai. Methods: Data was collected retrospectively from patients’ records at Rashid Hospital Child Psychiatry Service. …


Determinants Of Dental Caries In Children In The Middle East And North Africa Region: A Systematic Review Based On Literature Published From 2000 To 2019, Amal Elamin, Malin Garemo, Anzelle Mulder Dec 2021

Determinants Of Dental Caries In Children In The Middle East And North Africa Region: A Systematic Review Based On Literature Published From 2000 To 2019, Amal Elamin, Malin Garemo, Anzelle Mulder

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Background: Dental caries risk factors have been expanded to not only emphasize biology, dietary and oral habits but also broader social determinants such as socioeconomic factors and the utilization of health services. The aim was to review sociobehavioural/cultural and socioeconomic determinants of dental caries in children residing in the Middle East and North Africa (MENA) region. Methods: A search was conducted in the PubMed/Medline database and Google Scholar to identify studies published from 2000 to 2019 covering children using key search terms. In the initial stages, titles, abstracts and, if needed, full articles were screened for eligibility. In the final …


Maternal Investment, Life-History Trajectory Of The Off-Spring And Cardiovascular Disease Risk In Emirati Females In The United Arab Emirates, Rola Al Ghali, Linda Smail, Maryam Muqbel, Dalia Haroun Dec 2021

Maternal Investment, Life-History Trajectory Of The Off-Spring And Cardiovascular Disease Risk In Emirati Females In The United Arab Emirates, Rola Al Ghali, Linda Smail, Maryam Muqbel, Dalia Haroun

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Background: Variations in cardiovascular disease risk (CVD) are suggested to be partly influenced by factors that affect prenatal growth patterns and outcomes, namely degree of maternal investment (proxied by birth weight and gestational age). Using the life history trajectory model, this study investigates whether maternal investment in early prenatal life associates with menarcheal age and whether maternal investment affects CVD risk in adulthood and predicts adult size and adiposity levels. Methods: A cross-sectional study was conducted among 94 healthy Emirati females. Birth weight, gestational age and menarcheal age were obtained. Anthropometrical measurements, body composition analysis, and blood pressure values were …


Vaccine Versus Variants (3vs): Are The Covid-19 Vaccines Effective Against The Variants? A Systematic Review, Kadhim Hayawi, Sakib Shahriar, Mohamed Adel Serhani, Hany Alashwal, Mohammad M. Masud Nov 2021

Vaccine Versus Variants (3vs): Are The Covid-19 Vaccines Effective Against The Variants? A Systematic Review, Kadhim Hayawi, Sakib Shahriar, Mohamed Adel Serhani, Hany Alashwal, Mohammad M. Masud

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Background: With the emergence and spread of new SARS-CoV-2 variants, concerns are raised about the effectiveness of the existing vaccines to protect against these new variants. Although many vaccines were found to be highly effective against the reference COVID-19 strain, the same level of protection may not be found against mutation strains. The objective of this study is to systematically review relevant studies in the literature and compare the efficacy of COVID-19 vaccines against new variants. Methods: We conducted a systematic review of research published in Scopus, PubMed, and Google Scholar until 30 August 2021. Studies including clinical trials, prospective …


Associations Between Genetic Variants In The Vitamin D Metabolism Pathway And Severity Of Covid-19 Among Uae Residents, Fatme Al-Anouti, Mira Mousa, Spyridon N. Karras, William B. Grant, Zainab Alhalwachi, Laila Abdel-Wareth, Maimunah Uddin, Nawal Alkaabi, Guan K. Tay, Bassam Mahboub, Habiba Alsafar Nov 2021

Associations Between Genetic Variants In The Vitamin D Metabolism Pathway And Severity Of Covid-19 Among Uae Residents, Fatme Al-Anouti, Mira Mousa, Spyridon N. Karras, William B. Grant, Zainab Alhalwachi, Laila Abdel-Wareth, Maimunah Uddin, Nawal Alkaabi, Guan K. Tay, Bassam Mahboub, Habiba Alsafar

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Vitamin D has many effects on cells in the immune system. Many studies have linked low vitamin D status with severity of COVID-19. Genetic variants involved in vitamin D metabolism have been implicated as potential risk factors for severe COVID-19 outcomes. This study investigated how genetic variations in humans affected the clinical presentation of COVID-19. In total, 646 patients with SARS-CoV-2 infection were divided into two groups: noncritical COVID-19 (n = 453; 70.12%) and a critical group (n = 193; 29.87%). Genotype data on the GC, NADSYN1, VDR, and CYP2R1 genes along with data on serum 25-hydroxyvitamin D levels were …


Study Of Atmospheric Pollution And Health Risk Assessment: A Case Study For The Sharjah And Ajman Emirates (Uae), Yousef Nazzal, Nadine Bou Orm, Alina Barbulescu, Fares Howari, Manish Sharma, Alaa E. Badawi, Ahmed A. Al-Taani, Jibran Iqbal, Farid El Ktaibi, Cijo M. Xavier, Cristian Stefan Dumitriu Nov 2021

Study Of Atmospheric Pollution And Health Risk Assessment: A Case Study For The Sharjah And Ajman Emirates (Uae), Yousef Nazzal, Nadine Bou Orm, Alina Barbulescu, Fares Howari, Manish Sharma, Alaa E. Badawi, Ahmed A. Al-Taani, Jibran Iqbal, Farid El Ktaibi, Cijo M. Xavier, Cristian Stefan Dumitriu

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Dust is a significant pollution source in the United Arab Emirates (UAE) that impacts population health. Therefore, the present study aims to determine the concentration of heavy metals (Cd, Pb, Cr, Cu, Ni, and Zn) in the air in the Sharjah and Ajman emirates’ urban areas and assesses the health risk. Three indicators were used for this purpose: the average daily dose (ADD), the hazard quotient (HQ), and the health index (HI). Data were collected during the period April–August 2020. Moreover, the observation sites were clustered based on the pollutants’ concentration, given that the greater the heavy metal concentration is, …


Validation Of The Italian Translation Of The Perceived Stigma Scale And Resilience Assessment In Inflammatory Bowel Disease Patients, Sara Cococcia, Marco Vincenzo Lenti, Caterina Mengoli, Catherine Klersy, Federica Borrelli De Andreis, Matteo Secco, Jihane Ghorayeb, Mariangela Delliponti, Gino Roberto Corazza, Antonio Di Sabatino Oct 2021

Validation Of The Italian Translation Of The Perceived Stigma Scale And Resilience Assessment In Inflammatory Bowel Disease Patients, Sara Cococcia, Marco Vincenzo Lenti, Caterina Mengoli, Catherine Klersy, Federica Borrelli De Andreis, Matteo Secco, Jihane Ghorayeb, Mariangela Delliponti, Gino Roberto Corazza, Antonio Di Sabatino

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BACKGROUND Stigmatization is the separation of an individual from a group due to aspects that make them different. Resilience may in turn influence the perception of stigma. Patients with inflammatory bowel disease (IBD) are susceptible to stigma, although data are very limited. AIM To validate an Italian translation of the IBD perceived stigma scale (PSS) in relation to patients’ resilience. METHODS Consecutive IBD outpatients were prospectively enrolled (December 2018-September 2019) in an Italian, tertiary referral, IBD center. Clinical and demographic data were collected. Stigma and resilience were evaluated through the IBD-PSS and the 25-item Connor-Davidson Resilience Scale, respectively. The International …


Oral Health Of Children And Adolescents In The United Arab Emirates: A Systematic Review Of The Past Decade, Fatme Al Anouti, Myriam Abboud, Dimitrios Papandreou, Suzan Haidar, Nadine Mahboub, Rana Rizk Sep 2021

Oral Health Of Children And Adolescents In The United Arab Emirates: A Systematic Review Of The Past Decade, Fatme Al Anouti, Myriam Abboud, Dimitrios Papandreou, Suzan Haidar, Nadine Mahboub, Rana Rizk

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Oral diseases are a universal public health problem with serious health and economic burdens. These diseases are a major concern in the pediatric population specifically. In the United Arab Emirates (UAE), among all the diseases that affect children, oral diseases, particularly early childhood caries, are the most common despite improvement in the provision of oral health services. Enhancing oral health status is one of the key public health goals in the country. This current systematic review aims to summarize the available data on oral health among children and adolescents in the UAE over the past decade (2011–2021). The review was …


Evidence For Involvement Of Non‐Classical Pathways In The Protection From Uv‐Induced Dna Damage By Vitamin D‐Related Compounds, Warusavithana Gunawardena Manori De Silva, Jeremy Zhuo Ru Han, Chen Yang, Wannit Tongkao‐On, Bianca Yuko Mccarthy, Furkan Akif Ince, Andrew J A Holland, Robert Charles Tuckey, Andrzej T Slominski, Myriam Abboud, Katie Marie Dixon, Mark Stephen Rybchyn, Rebecca Sara Mason Sep 2021

Evidence For Involvement Of Non‐Classical Pathways In The Protection From Uv‐Induced Dna Damage By Vitamin D‐Related Compounds, Warusavithana Gunawardena Manori De Silva, Jeremy Zhuo Ru Han, Chen Yang, Wannit Tongkao‐On, Bianca Yuko Mccarthy, Furkan Akif Ince, Andrew J A Holland, Robert Charles Tuckey, Andrzej T Slominski, Myriam Abboud, Katie Marie Dixon, Mark Stephen Rybchyn, Rebecca Sara Mason

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The vitamin D hormone, 1,25dihydroxyvitamin D3 (1,25(OH)2D3), and related compounds derived from vitamin D3 or lumisterol as a result of metabolism via the enzyme CYP11A1, have been shown, when applied 24 hours before or immediately after UV irradiation, to protect human skin cells and skin from DNA damage due to UV exposure, by reducing both cyclobutane pyrimidine dimers (CPD) and oxidative damage in the form of 8‐oxo‐7,8‐dihydro‐2’‐ deoxyguanosine (8‐OHdG). We now report that knockdown of either the vitamin D receptor or the endoplasmic reticulum protein ERp57 by siRNA abolished the reductions in UV‐induced DNA damage with 20‐hydroxyvitamin D3 or 24‐hydroxylumisterol3, …


Investigating The Role Of Functional Polymorphism Of Maternal And Neonatal Vitamin D Binding Protein In The Context Of 25‐Hydroxyvitamin D Cutoffs As Determinants Of Maternal‐Neonatal Vitamin D Status Profiles In A Sunny Mediterranean Region, Spyridon N. Karras, Erdinç Dursun, Merve Alaylıoğlu, Duygu Gezen‐Ak, Cedric Annweiler, Fatme Al Anouti, Hana M.A. Fakhoury, Alkiviadis Bais, Dimitrios Kiortsis Sep 2021

Investigating The Role Of Functional Polymorphism Of Maternal And Neonatal Vitamin D Binding Protein In The Context Of 25‐Hydroxyvitamin D Cutoffs As Determinants Of Maternal‐Neonatal Vitamin D Status Profiles In A Sunny Mediterranean Region, Spyridon N. Karras, Erdinç Dursun, Merve Alaylıoğlu, Duygu Gezen‐Ak, Cedric Annweiler, Fatme Al Anouti, Hana M.A. Fakhoury, Alkiviadis Bais, Dimitrios Kiortsis

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Recent results indicate that dysregulation of vitamin D‐binding protein (VDBP) could be involved in the development of hypovitaminosis D, and it comprises a risk factor for adverse fetal, maternal and neonatal outcomes. Until recently, there was a paucity of results regarding the effect of maternal and neonatal VDBP polymorphisms on vitamin D status during pregnancy in the Mediterranean region, with a high prevalence of hypovitaminosis D. We aimed to evaluate the combined effect of maternal and neonatal VDBP polymorphisms and different maternal and neonatal 25‐hy-droxyvitamin D (25(OH)D) cut‐offs on maternal and neonatal vitamin D profile. Blood samples were obtained from …


Automatic Cerebrovascular Segmentation Methods - A Review, Fatma Taher, Neema Prakash Sep 2021

Automatic Cerebrovascular Segmentation Methods - A Review, Fatma Taher, Neema Prakash

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Cerebrovascular diseases are one of the serious causes for the increase in mortality rate in the world which affect the blood vessels and blood supply to the brain. In order, diagnose and study the abnormalities in the cerebrovascular system, accurate segmentation methods can be used. The shape, direction and distribution of blood vessels can be studied using automatic segmentation. This will help the doctors to envisage the cerebrovascular system. Due to the complex shape and topology, automatic segmentation is still a challenge to the clinicians. In this paper, some of the latest approaches used for segmentation of magnetic resonance angiography …


A Mysterious Sensation About Sleep And Health: The Role Of Interoception, Teresa Arora, Mariapaola Barbato, Shaikha Al Hemeiri, Omar M. Omar, Maryam A. Aljassmi Aug 2021

A Mysterious Sensation About Sleep And Health: The Role Of Interoception, Teresa Arora, Mariapaola Barbato, Shaikha Al Hemeiri, Omar M. Omar, Maryam A. Aljassmi

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BACKGROUND: Interoception is mental awareness, recognition and acknowledgement of physiological body signals. Understanding the role of sleep and interoception may provide a better understanding surrounding the sleep-health connection. Our primary objective was to examine the potential relationships between subjective sleep quality and multiple dimensions of interoceptive abilities in a large sample of young adults, a group who are vulnerable to sleep impairment and its widespread health consequences. METHODS: We conducted an online cross-sectional survey targeting young adults, aged 18-25 years. The Pittsburgh Sleep Quality Index (PSQI) was used to identify subjective sleep quality and the Multidimensional Assessment of Interoceptive Awareness …


Early Screening For Post-Stroke Depression, And The Effect On Functional Outcomes, Quality Of Life And Mortality: A Protocol For A Systematic Review And Meta-Analysis, Sudhakar Selvaraj, Teresa Arora, Tahani Casameni Montiel, Ian Grey, Hind Alfraih, Melissa Fadipe, Robert Suchting, Sean Savitz, Jennifer E. Sanner Beauchamp, Linda Östlundh Aug 2021

Early Screening For Post-Stroke Depression, And The Effect On Functional Outcomes, Quality Of Life And Mortality: A Protocol For A Systematic Review And Meta-Analysis, Sudhakar Selvaraj, Teresa Arora, Tahani Casameni Montiel, Ian Grey, Hind Alfraih, Melissa Fadipe, Robert Suchting, Sean Savitz, Jennifer E. Sanner Beauchamp, Linda Östlundh

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INTRODUCTION: Post-stroke depression (PSD) is a severe complication of cerebrovascular stroke affecting about one-third of stroke survivors. Moreover, PSD is associated with functional recovery and quality of life (QOL) in stroke survivors. Screening for PSD is recommended. There are, however, differences in the literature on the impact of early screening on functional outcomes. In this systematic review, we synthesise the currently available literature regarding the associations between timing and setting of PSD screening and mortality, QOL and functional outcomes in stroke survivors. METHODS AND ANALYSIS: We will systematically search electronic databases including PubMed, Embase, APA PsycINFO, Web of Science, Scopus …


Carveol Attenuates Seizure Severity And Neuroinflammation In Pentylenetetrazole-Kindled Epileptic Rats By Regulating The Nrf2 Signaling Pathway, Arooj Mohsin Alvi, Lina Tariq Al Kury, Abdullah Alattar, Ikram Ullah, Asmaa Jan Muhammad, Reem Alshaman, Fawad Ali Shah, Arif Ullah Khan, Jinxing Feng, Shupeng Li Aug 2021

Carveol Attenuates Seizure Severity And Neuroinflammation In Pentylenetetrazole-Kindled Epileptic Rats By Regulating The Nrf2 Signaling Pathway, Arooj Mohsin Alvi, Lina Tariq Al Kury, Abdullah Alattar, Ikram Ullah, Asmaa Jan Muhammad, Reem Alshaman, Fawad Ali Shah, Arif Ullah Khan, Jinxing Feng, Shupeng Li

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Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks. Numerous studies have suggested a strong correlation between oxidative stress and neuroinflammation in several neurodegenerative disorders including epilepsy. This study is aimed at investigating the neuroprotective effects of the natural compound carveol against pentylenetetrazole- (PTZ-) induced kindling and seizure model. Two different doses of carveol (10 mg/kg and 20 mg/kg) were administered to male rats to determine the effects and the effective dose of carveol and to further demonstrate the mechanism of action of nuclear factor E2-related factor (Nrf2) in PTZ-induced kindling model. Our results demonstrated reduced levels of …


Urinary Minerals Excretion Among Primary Schoolchildren In Dubai—United Arab Emirates, Rola Al Ghali, Carla El-Mallah, Omar Obeid, Ola El-Saleh, Linda Smail, Dalia Haroun Aug 2021

Urinary Minerals Excretion Among Primary Schoolchildren In Dubai—United Arab Emirates, Rola Al Ghali, Carla El-Mallah, Omar Obeid, Ola El-Saleh, Linda Smail, Dalia Haroun

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INTRODUCTION: Urinary excretion of calcium (Ca), magnesium (Mg), phosphorus (P), iodine and fluoride is used to assess their statuses and/or the existence of metabolic abnormalities. In the United Arab Emirates (UAE), the urinary concentration of these minerals among children have not been documented. MATERIALS AND METHODS: A cross-sectional study, including 593 subjects (232 boys and 361 girls), was conducted among healthy 6 to 11-year-old Emirati children living in Dubai. Non-fasting morning urine samples and anthropometrical measurements were collected and analyzed. Results were expressed as per mg of creatinine (Cr). RESULTS: On average, estimated Cr excretion was 17.88±3.12 mg/kg/d. Mean urinary …


Levels Of Trust In Information Sources As A Predictor Of Protective Health Behaviors During Covid-19 Pandemic: A Uae Cross-Sectional Study, Maria J. Figueiras, Jihane Ghorayeb, Mariana V. C. Coutinho, João Marôco, Justin Thomas Jul 2021

Levels Of Trust In Information Sources As A Predictor Of Protective Health Behaviors During Covid-19 Pandemic: A Uae Cross-Sectional Study, Maria J. Figueiras, Jihane Ghorayeb, Mariana V. C. Coutinho, João Marôco, Justin Thomas

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Health information sources and the level of trust in a particular source may influence the subsequent adoption of advocated health behaviors. Information source preference and levels of trust are also likely to be influenced by sociodemographic (culture, age, gender) variables. Understanding these source-trust-behavior relationships across various national and cultural contexts is integral to improved health messaging. The present study identified the sources most frequently consulted to obtain information about COVID-19 during the pandemic's early stages in the United Arab Emirates (UAE). The study quantified levels of trust across an array of information sources, factoring in sociodemographic variables. Finally, the study …


Patterns Of Tobacco Smoking And Nicotine Vaping Among University Students In The United Arab Emirates: A Cross-Sectional Study, Luai A. Ahmed, Marina Verlinden, Mariam Ali Alobeidli, Reem Hamad Alahbabi, Radeya Alkatheeri, Basema Saddik, Abderrahim Oulhaj, Rami H. Al-Rifai Jul 2021

Patterns Of Tobacco Smoking And Nicotine Vaping Among University Students In The United Arab Emirates: A Cross-Sectional Study, Luai A. Ahmed, Marina Verlinden, Mariam Ali Alobeidli, Reem Hamad Alahbabi, Radeya Alkatheeri, Basema Saddik, Abderrahim Oulhaj, Rami H. Al-Rifai

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Various forms of tobacco smoking and nicotine vaping tools are available on the market. This study quantified the prevalence of and identified factors associated with patterns of smoking and nicotine vaping among university students in the United Arab Emirates (UAE). A cross-sectional sample of students enrolled in three public universities was surveyed. Self-reported current smoking and nicotine vaping were recorded. Of 1123 students, 81.7% completed the online survey (mean age, 20.7 ± 3.4 (SD) years; 70.7% females). The prevalence of current smoking was 15.1% while the prevalence of current nicotine vaping was nearly 4.0%. Among current smokers, 54.7% reported conventional …


Administering A Combination Of Online Dietary Assessment Tools, The Automated Self-Administered 24-Hour Dietary Assessment Tool, And Diet History Questionnaire Ii, In A Cohort Of Adults In Alberta's Tomorrow Project, Nathan M. Solbak, Paula J. Robson, Geraldine Lo Siou, Ala Al Rajabi, Seol Paek, Jennifer E. Vena, Sharon I. Kirkpatrick Jul 2021

Administering A Combination Of Online Dietary Assessment Tools, The Automated Self-Administered 24-Hour Dietary Assessment Tool, And Diet History Questionnaire Ii, In A Cohort Of Adults In Alberta's Tomorrow Project, Nathan M. Solbak, Paula J. Robson, Geraldine Lo Siou, Ala Al Rajabi, Seol Paek, Jennifer E. Vena, Sharon I. Kirkpatrick

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Background: Evidence suggests that combining tools that gather short- and long-term dietary data may be the optimal approach for the assessment of diet–disease associations in epidemiologic studies. Online technology can reduce the associated burdens for researchers and participants, but feasibility must be demonstrated in real-world settings before wide-scale implementation. Objective: The objective of this study was to determine the feasibility and acceptability of combining web-based tools (the Automated Self-Administered 24-hour Dietary Assessment Tool [ASA24-2016] and the past-year Diet History Questionnaire II [DHQ-II]) in a subset of participants in Alberta's Tomorrow Project, a prospective cohort. Design: For this feasibility study, invitations …


Measuring Mental Health Literacy: Adaptation And Validation Of The Portuguese Version Of The Mental Health Literacy Scale (Mhls), David Dias Neto, Ines Rocha, Maria João Figueiras, Ana Nunes Da Silva Jun 2021

Measuring Mental Health Literacy: Adaptation And Validation Of The Portuguese Version Of The Mental Health Literacy Scale (Mhls), David Dias Neto, Ines Rocha, Maria João Figueiras, Ana Nunes Da Silva

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Understanding mental health literacy is essential for promoting empowerment and proactivity in patients, reducing stigma, and increasing population awareness. The constitutive dimensions of mental health literacy are still being researched, and instruments’ research can shed light on the involved processes. The Mental Health Literacy Scale (MHLS) is a self-report measure of mental health literacy. This study aimed to adapt the MHLS to Portuguese and evaluate mental health literacy in a broad sample. A broad sample of 337 individuals participated in the adaptation. Besides filling out the MHLS, the participants were invited to fill out a general lifestyle measure. The global …


Early Assessment Of Lung Function In Coronavirus Patients Using Invariant Markers From Chest X-Rays Images, Mohamed Elsharkawy, Ahmed Sharafeldeen, Fatma Taher, Ahmed Shalaby, Ahmed Soliman, Ali Mahmoud, Mohammed Ghazal, Ashraf Khalil, Norah Saleh Alghamdi, Ahmed Abdel Khalek Abdel Razek, Eman Alnaghy, Moumen T. El-Melegy, Harpal Singh Sandhu, Guruprasad A. Giridharan, Ayman El-Baz Jun 2021

Early Assessment Of Lung Function In Coronavirus Patients Using Invariant Markers From Chest X-Rays Images, Mohamed Elsharkawy, Ahmed Sharafeldeen, Fatma Taher, Ahmed Shalaby, Ahmed Soliman, Ali Mahmoud, Mohammed Ghazal, Ashraf Khalil, Norah Saleh Alghamdi, Ahmed Abdel Khalek Abdel Razek, Eman Alnaghy, Moumen T. El-Melegy, Harpal Singh Sandhu, Guruprasad A. Giridharan, Ayman El-Baz

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The primary goal of this manuscript is to develop a computer assisted diagnostic (CAD) system to assess pulmonary function and risk of mortality in patients with coronavirus disease 2019 (COVID-19). The CAD system processes chest X-ray data and provides accurate, objective imaging markers to assist in the determination of patients with a higher risk of death and thus are more likely to require mechanical ventilation and/or more intensive clinical care.To obtain an accurate stochastic model that has the ability to detect the severity of lung infection, we develop a second-order Markov-Gibbs random field (MGRF) invariant under rigid transformation (translation or …


Sense Of Effort Is Distorted In People With Chronic Low Back Pain, Michel W. Coppieters, Jesper Andersen, Håvard Selbæk, Kjell Herland, Rahma Ajja, Harald Markussen, Paul W. Hodges Jun 2021

Sense Of Effort Is Distorted In People With Chronic Low Back Pain, Michel W. Coppieters, Jesper Andersen, Håvard Selbæk, Kjell Herland, Rahma Ajja, Harald Markussen, Paul W. Hodges

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Background: Proprioceptive deficits in people with low back pain (LBP) have traditionally been attributed to altered paraspinal muscle spindle afference and its central processing. Studies conducted in the upper limb demonstrated that sense of effort is also an important source of kinaesthetic information. Objectives: To better understand proprioceptive deficits in people with chronic LBP (cLBP), this study aimed to test whether sense of effort is affected in people with cLBP. Design: Cross-sectional study. Method: Fourteen participants with cLBP and fourteen healthy participants performed a 120 s force matching task with their trunk extensor muscles at a low intensity. Results: When …