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The Effect Of Heparinoid As Systemic Prophylactic Anticoagulants On Covid-19 Patient Mortality And Its Safety Profiles: A Systematic Review And Meta-Analysis, Ariska Deffy Anggarany, Rani Sauriasari, Muhammad Alkaff, Famila Takhwifa, Hayatun Nufus, Diana Paramita Dec 2021

The Effect Of Heparinoid As Systemic Prophylactic Anticoagulants On Covid-19 Patient Mortality And Its Safety Profiles: A Systematic Review And Meta-Analysis, Ariska Deffy Anggarany, Rani Sauriasari, Muhammad Alkaff, Famila Takhwifa, Hayatun Nufus, Diana Paramita

Pharmaceutical Sciences and Research

Coagulopathy is one of the complications of COVID-19 and is associated with a higher risk of mortality. However, evidence regarding the effectiveness and safety of anticoagulant therapy in various doses among COVID-19 patients is limited. This systematic review and meta-analysis aims to review and explore the effect of using heparinoids as a systemic anticoagulant at prophylactic doses on mortality in COVID-19 patients. Systematic searches were conducted of various databases (Pubmed, ScienceDirect, SpringerLink, Scopus, and ProQuest) covering the period 2019-2021. We assessed the quality of the articles using the STROBE checklist. Studies with a high risk of bias were excluded before …


Depressive Symptoms As A Predictor Factor Of All-Cause Mortality Within Six Months In Elderly Hemodialysis Patients, Langgeng Perdhana, Shofa Chasan, Yudo Murti Mupangati, Siti Nuraini Dec 2021

Depressive Symptoms As A Predictor Factor Of All-Cause Mortality Within Six Months In Elderly Hemodialysis Patients, Langgeng Perdhana, Shofa Chasan, Yudo Murti Mupangati, Siti Nuraini

Jurnal Penyakit Dalam Indonesia

Introduction. Depression is a mental disorder that is often found in the elderly and hemodialysis patients, resulting in bad effects on patients. There is no study on the relationship between depression and all-cause mortality risk in elderly hemodialysis patients in Indonesia. This study aimed to determine the role of depression as a predictor factor of all-cause mortality within 6 months in elderly hemodialysis patients. Methods. A prospective cohort study was conducted from February to August 2020 at the hemodialysis unit of Roemani Muhammadiyah Hospital, Semarang. The inclusion criteria were elderly patients (aged ≥60 years), undergoing hemodialysis ≥3 months, hemodialysis frequency …


Prognostic And Predictive Factors Of Mortality In Burn Patients At Dr. Cipto Mangunkusumo General Hospital, Indonesia, Muhamad Irfan A. Hasibuan, Yefta Moenadjat Dec 2021

Prognostic And Predictive Factors Of Mortality In Burn Patients At Dr. Cipto Mangunkusumo General Hospital, Indonesia, Muhamad Irfan A. Hasibuan, Yefta Moenadjat

The New Ropanasuri Journal of Surgery

Introduction. Some prognostic– and predictive factors in burn have never been investigated in Indonesian specific characteristics, which is delayed treatment. A study was conducted to determine prognostic and predictive factors in this specific characteristic.

Method. A retrospective cohort focused on burn mortality in extensive burns managed in CMGH from 1998–2010. Some known prognostic– and predictive factors and unknown ones were the variables of interest. Bivariate and multivariate using logistic regression analysis proceeded to find out these factors.

Results. Out of all factors investigated, the variables that showed a significant correlation were: TBSA, inhalation injury, Baux score, revised …


Demography, Comorbidities, Biomarkers, And Severity Of Infection In Admitted Covid-19 Patients: Experience From A Tertiary Care Hospital In South India, Indira Kedlaya, Yashas V. Kedlaya, Saad H. Usmani Dec 2021

Demography, Comorbidities, Biomarkers, And Severity Of Infection In Admitted Covid-19 Patients: Experience From A Tertiary Care Hospital In South India, Indira Kedlaya, Yashas V. Kedlaya, Saad H. Usmani

Manipal Journal of Medical Sciences

Introduction: This retrospective study analyses the demographics, clinical features, and comorbidities of patients admitted with COVID-19. The study also evaluates the association of two biomarkers namely D-dimer and CRP (C-reactive protein) with the severity of the infection. Methods: Data of COVID-19 patients admitted from 1 June 2020 to 31 August 2020 was collected based on age, sex, date of admission and discharge, the severity of infection, final disposition, treatment, biomarkers (C-reactive protein and D-dimer), other associated presentations, and comorbidities through a chart review. The severity of infection was categorized into asymptomatic, mild, moderate, or severe, based on WHO criteria. Results: …


Mortality And Morbidity Among Preterm Neonates Admitted To Al-Mukalla Maternity And Childhood Hospital, Yemen, Hanan Saeed Bin Gouth, Saleh Awad Bahwel, Mazin Ahmed Jawass, Ali Salim Bahartha, Fauzia Faraj Bamatraf Dec 2021

Mortality And Morbidity Among Preterm Neonates Admitted To Al-Mukalla Maternity And Childhood Hospital, Yemen, Hanan Saeed Bin Gouth, Saleh Awad Bahwel, Mazin Ahmed Jawass, Ali Salim Bahartha, Fauzia Faraj Bamatraf

Hadhramout University Journal of Natural & Applied Sciences

Globally, preterm birth is a major clinical problem associated with significant mortality and morbidity in the perinatal, neonatal, and childhood periods and even in adulthood. The study aimed to evaluate the mortality and morbidity of preterm neonates admitted to Maternity and Childhood Hospital (MCH) in Al-Mukalla. A retrospective case-control study at a ratio of 1 1 was conducted in the neonatal unit of pediatric ward from October 2012 to October 2013. The study included records of 104 preterm neonates as cases and equal numbers of full term neonates as control. The results showed high mortality rate (22.6%) among the neonates. …


An Analysis Of Survival And Mortality Among Patients Admitted To Surgical Icu In Ibin Sina Hospital In Mukalla City, Yemen, Abdulla Saleh Alyamani, Salah Ahmed Binzaiad, Khalid Ahmed Baeassa Nov 2021

An Analysis Of Survival And Mortality Among Patients Admitted To Surgical Icu In Ibin Sina Hospital In Mukalla City, Yemen, Abdulla Saleh Alyamani, Salah Ahmed Binzaiad, Khalid Ahmed Baeassa

Hadhramout University Journal of Natural & Applied Sciences

The intensive Care Unit (ICU) is an important unit that takes care of patients with severely life-threatening illnesses and injuries in order to maintain normal body functions. This study aims to estimate survival and mortality among patients admitted to Surgical ICU (SICU ) in Ibin Sina hospital in Mukalla city. A total of 320 patients records from surgical ICU were reviewed during the last six months in 2018 to estimate the survival and mortality rate using Kaplan Meier to evaluate Hazard Rate (HR) using Cox regression. The mortality rate was found 20%. Out of all dead patients 52 (81.2%) were …


Correlation Between Mortality Due To Covid-19, Wealth Index, Human Development And Population Density In Districts Of Metropolitan Lima During 2020, Zalia E. Dorregaray-Farge, Alonso Soto, Jhony A. De La Cruz Vargas Oct 2021

Correlation Between Mortality Due To Covid-19, Wealth Index, Human Development And Population Density In Districts Of Metropolitan Lima During 2020, Zalia E. Dorregaray-Farge, Alonso Soto, Jhony A. De La Cruz Vargas

Revista de la Facultad de Medicina Humana

Objectives: To determine the correlation between mortality from COVID-19 and the percentage of poverty and the district Human Development Index (HDI) in the department of Lima. Methods: Ecological observational correlation study. The population were patients who died from COVID-19 in metropolitan Lima. All deceased patients reported in the open database of the Ministry of Health were included. The dependent variable was the mortality from COVID-19 calculated by dividing the number of deaths by the total population of the districts and the independent variables were the percentage of poverty and HDI. A secondary analysis was performed evaluating the fatality from COVID-19. …


The Impact Of Patient-Dependent Risk Factors On Morbidity And Mortality Following Gastric Surgery For Malignancies, Bogdan Dumitriu, Sebastian Valcea, Gabriel Andrei, Mircea Beuran Oct 2021

The Impact Of Patient-Dependent Risk Factors On Morbidity And Mortality Following Gastric Surgery For Malignancies, Bogdan Dumitriu, Sebastian Valcea, Gabriel Andrei, Mircea Beuran

Journal of Mind and Medical Sciences

Gastric cancer remains a leading cause of mortality worldwide. The treatment for gastric cancer is multimodal, in which gastrectomy remains the only curative approach. However, gastric resection is often associated with increased morbidity and mortality rates, depending on several factors. These factors can be attributed to the patient as comorbidities or effects of the disease upon him and, on the other hand, there are risk factors independent of the patient, such as aspects of the tumor (type, staging, location), experience of the surgical and anesthetic team, logistics of the hospital, yield of adjuvant therapies etc. We recognize the fact that …


The Role Of Albumin And Hemoglobin As Predictors Of 28-Day Mortality In Elderly Sepsis Patients In Mohammad Hoesin Hospital Palembang, Widya Mandala Sari Gultom, Nur Riviati, Rizky Perdana, Syarif Husin Sep 2021

The Role Of Albumin And Hemoglobin As Predictors Of 28-Day Mortality In Elderly Sepsis Patients In Mohammad Hoesin Hospital Palembang, Widya Mandala Sari Gultom, Nur Riviati, Rizky Perdana, Syarif Husin

Jurnal Penyakit Dalam Indonesia

Introduction. Sepsis is defined as organ dysfunction caused by dysregulation of the host’s response to infection. The majority of sepsis are experienced by elderly patients with high mortality rates. In the condition of sepsis, there are various body mechanisms that cause a decrease in albumin and hemoglobin. This study is to determine the predictive value of albumin and hemoglobin levels on 28-day mortality of elderly sepsis patients.


In-Hospital Mortality Risk Factors Among Hospitalized Geriatric Patients: A Cohort Study On Tertiary Referral Hospital In Indonesia, Fadhil Abiyyu Yofi, Arlia Ayu Damayanti, Novira Widajanti Sep 2021

In-Hospital Mortality Risk Factors Among Hospitalized Geriatric Patients: A Cohort Study On Tertiary Referral Hospital In Indonesia, Fadhil Abiyyu Yofi, Arlia Ayu Damayanti, Novira Widajanti

Jurnal Penyakit Dalam Indonesia

Introduction. Decreasing fertility rates and increasing life expectancy cause an increase in the population of the elderly, with the number of elderly in the world is estimated to increase from 9.3% in 2020 to 16.0% in 2050. 24.35% of the elderly in Indonesia experience illness, and 8.71% have been hospitalized in one year. This study aimed to determine the risk factors for the death of elderly who were hospitalized.


Comparison Of Red Cell Distribution Width Values Towardsmortality In Adult And Elderly Hospital-Acquired Pneumoniapatients In Dr. Sardjito Hospital, Desty Gusti Sari, Rizka Humardewayanti Asdie, Heni Retnowulan Jun 2021

Comparison Of Red Cell Distribution Width Values Towardsmortality In Adult And Elderly Hospital-Acquired Pneumoniapatients In Dr. Sardjito Hospital, Desty Gusti Sari, Rizka Humardewayanti Asdie, Heni Retnowulan

Jurnal Penyakit Dalam Indonesia

Introduction. Hospital-acquired pneumonia (HAP) is a major cause of morbidity and mortality. Red cell distribution width (RDW) is associated with mortality in patients with septic shock and community-acquired pneumonia (CAP). However, little is known about the effect of elevation of RDW value on mortality in HAP patients, especially in the elderly population who have a worse prognosis. This study aimed to determine the proportion of adult and elderly HAP patients who have an increase in RDW value and the relation between the increase in RDW value to the risk of mortality in HAP patients during hospitalization. Methods. A cross-sectional and …


Comparative Study Of Perinatal Mortality, Stillbirths, And Neonatal Mortality From 2010 To 2018 In Developing And Developed Nations With Reference To Malaysia, Sujata Khobragade, Yadneshwar Khobragade, Adinegara Lutfi Abas Jun 2021

Comparative Study Of Perinatal Mortality, Stillbirths, And Neonatal Mortality From 2010 To 2018 In Developing And Developed Nations With Reference To Malaysia, Sujata Khobragade, Yadneshwar Khobragade, Adinegara Lutfi Abas

Manipal Journal of Medical Sciences

Background: Malaysia being an emerging economy has done well in the health sector. The perinatal mortality is reduced significantly but a slight upward trend was seen after 2015 in less developed states. This prompted us to conduct a review of perinatal, stillbirth, and neonatal deaths in Malaysia and compare them with other developing and developed countries. Aims and objectives: To find out: (1) Perinatal, neonatal and stillbirth rates from 2010 to 2018 in Malaysia, and (2) Compare it with developed and developing countries for the same duration. (3) To study contributary factors responsible for perinatal mortality, stillbirths and neonatal deaths …


Regional Distribution Of Covid-19 Mortality In Peru, Maria Flores López, Alonso Soto Tarazona, Jhony A. De La Cruz-Vargas Mar 2021

Regional Distribution Of Covid-19 Mortality In Peru, Maria Flores López, Alonso Soto Tarazona, Jhony A. De La Cruz-Vargas

Revista de la Facultad de Medicina Humana

Objectives: Compare the death rate from COVID-19 at the national level by regions and departments from March to September 2020. Methods: Quantitative, observational, cross-sectional, ecological and retrospective study. The data was extracted from the National Death System (SINADEF) in Microsoft Excel 2016 and imported into Stata. The variables were described as frequencies and percentages. Mortality was obtained by dividing the total deaths over the total population according to the last census. An adjusted exploratory analysis was performed using robust regression methods to evaluate the association between mortality by department and regions adjusted for age and sex of the deceased. P <0.05 was considered significant. Results: 32535 deaths were reported, 69.84% were male and the median was 67. The mortality rate in the Costa region 145 deaths were calculated (n = 24,276), followed by Sierra with 51 (n = 4434) and Selva with 63 (n = 2545). There were significant differences in mortality according to the region, in the comparison of the coast with the Sierra region a beta coefficient of -96.28 was found (p <0.001 IC -123.76 -68.77), while in the comparison with the Selva it was determined a coefficient of -50.38 (p 0.01 95% CI -91.47 -9.29). No significant association was found between the mortality rate and the average age or sex of the deceased by department. Conclusion: The death rate from COVID-19 at the national level was 101 per 100 000 inhabitants. The mortality rate found was higher on the Costa region than in the Sierra and Selva, regardless of the proportion of men, women or age.


Association Between Vitamin D Deficiency And Sepsis In Pediatric Icu, Ahmed A. Khattab, Aliaa A. Abdel-Aziz, Fady M. El-Gendy, Rehab G. Naser Mar 2021

Association Between Vitamin D Deficiency And Sepsis In Pediatric Icu, Ahmed A. Khattab, Aliaa A. Abdel-Aziz, Fady M. El-Gendy, Rehab G. Naser

Menoufia Medical Journal

Objective To evaluate association between 25-hydroxyvitamin D [25(OH)D] and sepsis in pediatric ICU (PICU). Background Vitamin D is a fat-soluble steroid hormone that helps maintain proper calcium homeostasis and has a role in the function of the immune system. Data on the prevalence of vitamin D deficiency (VDD) in PICU in children with sepsis and its association with poor outcome were obtained. Patients and methods This study was carried out on 45 patients with sepsis admitted to the PICU, Pediatric Department, Menoufia University Hospital, and 45 controls, who attended the patient clinic and were found to be healthy. Demographic data, …


Anemia And Cancer Survival, A Peruvian Study With A 5-Year Follow-Up, María Loo-Valverde, Jennyfer E. Garcia Arispe, Willer Chanduví, Jose M. Vela-Ruiz, Rocio Guillen-Ponce, Jhony A. De La Cruz-Vargas Mar 2021

Anemia And Cancer Survival, A Peruvian Study With A 5-Year Follow-Up, María Loo-Valverde, Jennyfer E. Garcia Arispe, Willer Chanduví, Jose M. Vela-Ruiz, Rocio Guillen-Ponce, Jhony A. De La Cruz-Vargas

Revista de la Facultad de Medicina Humana

Introduction: Anemia is a serious public health. Several studies indicate that anemia status is a factor that might influence survival and response to cancer treatment in patients. Objective: To determine the relationship between anemia and 5-year survival in cancer patients. Methods: Observational, analytical, and retrospective cohort study. The sample population consisted of novel diagnosed cancer patients registered for hospital care with their respective follow up from 2014 until 2019. Time to death, presence of anemia, and other variables were evaluated. Survival was determined using Kaplan Meier curves and analyzed using the log-rank test. Hazard ratio and risk were determined in …


Risk Factors For Mortality From Covid-19 In Hospitalized Patients: A Logistic Regression Model, Irma Luz Yupari, Lucia Bardales Aguirre, Julio Rodriguez Azabache, Jaylin Barros Sevillano, Angela Rodríguez Díaz Mar 2021

Risk Factors For Mortality From Covid-19 In Hospitalized Patients: A Logistic Regression Model, Irma Luz Yupari, Lucia Bardales Aguirre, Julio Rodriguez Azabache, Jaylin Barros Sevillano, Angela Rodríguez Díaz

Revista de la Facultad de Medicina Humana

Introduction: The population is susceptible to COVID-19 and knowing the most predominant characteristics and comorbidities of those affected is essential to diminish its effects. Objective: This study analyzed the biological, social and clinical risk factors for mortality in hospitalized patients with COVID-19 in the district of Trujillo, Peru. Methods: A descriptive type of study was made, with a quantitative approach and a correlational, retrospective, cross-sectional design. Data was obtained from the Ministry of Health’s database, with a sample of 64 patients from March to May 2020. Results: 85,71% of the total deceased are male, the most predominant occupation is Retired …


Hypoalbuminemia As A Predicator Of Mortality Of Sepsis From Covid-19. Hospital Ii Chocope, 2020., Alex Brandon Lopez, Graciela Aguilar Murillo, Alicia Muñoz Neciosup, Evelyn Goicochea Rios Mar 2021

Hypoalbuminemia As A Predicator Of Mortality Of Sepsis From Covid-19. Hospital Ii Chocope, 2020., Alex Brandon Lopez, Graciela Aguilar Murillo, Alicia Muñoz Neciosup, Evelyn Goicochea Rios

Revista de la Facultad de Medicina Humana

A correlational type investigation was carried out evaluating 145 patients with covid-19 sepsis. Objectives: To determine whether hypoalbuminemia is a predictor of mortality and to identify the serum albumin value most frequently related to lethality. Method: Patients older than or equal to 18 years seen at Hospital II Chocope during May to August 2020 were included. Patients with oncological pathologies and incomplete medical records were excluded. The documentary analysis technique was used, by reviewing medical records. Results: There was a statistically significant association between hypoalbuminemia and mortality (p = 0.00), patients with hypoalbuminemia had 3 times the risk of dying. …


Clinical Course Of Covid-19 Disease In Immunosuppressed Renal Transplant Patients, Hamad Dhei̇r, Savaş Si̇pahi̇, Selçuk Yaylaci, Esma Seda Çeti̇n, Ahmed Bi̇lal Genç, Necatti̇n Firat, Mehmet Köroğlu, Gürkan Muratdaği, Yakup Tomak, Kezban Özmen Süner, Ömer Faruk Ateş, Oğuz Karabay Jan 2021

Clinical Course Of Covid-19 Disease In Immunosuppressed Renal Transplant Patients, Hamad Dhei̇r, Savaş Si̇pahi̇, Selçuk Yaylaci, Esma Seda Çeti̇n, Ahmed Bi̇lal Genç, Necatti̇n Firat, Mehmet Köroğlu, Gürkan Muratdaği, Yakup Tomak, Kezban Özmen Süner, Ömer Faruk Ateş, Oğuz Karabay

Turkish Journal of Medical Sciences

Background/aim: We aimed to identify clinical settings of renal transplant patients with COVID-19. Materials and methods: In this retrospective study, we included kidney transplant inpatients with laboratory confirmed COVID-19 who had been discharged or had died by October 1st, 2020. Characteristics of the patients, including basal and last outpatient biochemical parameters were recorded. Discontinuation or dosage reduction of immunosuppressives and other treatment information was documented. Results: Twenty patients were included in this study, of whom 18 were discharged and 2 died in hospital. The mean duration of hospitalization and follow-up were 9.7 ± 6.4 days and 4.5 ± 2.0 months, …


The Predictive And Diagnostic Accuracy Of Long Pentraxin-3 In Covid-19 Pneumonia, Ahmed Bi̇lal Genç, Selçuk Yaylaci, Hamad Dhei̇r, Ahmed Ci̇had Genç, Kubi̇lay İşsever, Deni̇z Çeki̇ç, Havva Kocayi̇ği̇t, Erdem Çokluk, Alper Karacan, Mehmet Ramazan Şekeroğlu, Hande Toptan, Ertuğrul Güçlü Jan 2021

The Predictive And Diagnostic Accuracy Of Long Pentraxin-3 In Covid-19 Pneumonia, Ahmed Bi̇lal Genç, Selçuk Yaylaci, Hamad Dhei̇r, Ahmed Ci̇had Genç, Kubi̇lay İşsever, Deni̇z Çeki̇ç, Havva Kocayi̇ği̇t, Erdem Çokluk, Alper Karacan, Mehmet Ramazan Şekeroğlu, Hande Toptan, Ertuğrul Güçlü

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study is to evaluate serum pentraxin-3 (PTX-3) levels in Sars-CoV-2 virus infection (COVID-19) patients and to investigate whether PTX-3 predicts the disease prognosis. Materials and methods: This study was conducted on 88 confirmed COVID-19 patients who were hospitalized due to symptomatic pneumonia between April 15 and August 15, 2020. The patients were divided into two groups as survived patients and non-survived patients. Both groups were compared according to demographic features, comorbid conditions and measurement of the PTX-3 and other laboratory parameters of the patients. Results: Of 88 patients with COVID-19, 59 (67%) were discharged with …


A Comparison Of Rates And Severity Of Chronic Kidney Disease In Deceased-Donor Andliving-Donor Liver Transplant Recipients: Times Matter, Yücel Yankol, Emily Bugeaud, Tiffany Zens, Michael Rizzari, Nesi̇mi̇ Meci̇t, Glen E. Leverson, David Foley, Joshua D. Mezrich, Turan Kanmaz, Oya Münevver Andaçoğlu, Anthony M. D'Alessandro, Koray Sadik Acarli, Münci̇ Kalayoğlu, Luis A. Fernandez Jan 2021

A Comparison Of Rates And Severity Of Chronic Kidney Disease In Deceased-Donor Andliving-Donor Liver Transplant Recipients: Times Matter, Yücel Yankol, Emily Bugeaud, Tiffany Zens, Michael Rizzari, Nesi̇mi̇ Meci̇t, Glen E. Leverson, David Foley, Joshua D. Mezrich, Turan Kanmaz, Oya Münevver Andaçoğlu, Anthony M. D'Alessandro, Koray Sadik Acarli, Münci̇ Kalayoğlu, Luis A. Fernandez

Turkish Journal of Medical Sciences

Background/aim: The progression of chronic kidney disease (CKD) in recipients of living-donor liver transplant (LDLT) compared to deceased-donor liver transplant (DDLT) has not been studied in the literature. We hypothesize that CKD stage progression in LDLT recipients is reduced compared to that of their DDLT counterparts. Materials and methods: A retrospective study was undertaken including 999 adult, single-organ, primary liver transplant recipients (218 LDLT and 781 DDLT) at 2 centers between January 2003 and December 2012, in which CKD progression and regression were evaluated within the first 3 years after transplantation. Results: Waiting time from evaluation to transplantation was significantly …


Can Thrombocytosis Or Thrombocytopenia Predict Complicated Clinical Course And30-Days Mortality In Patients With Pneumonia?, Razi̇ye Si̇nem Misirlioğlu, Ersi̇n Aksay, Emre Şanci, Kemal Can Tertemi̇z Jan 2021

Can Thrombocytosis Or Thrombocytopenia Predict Complicated Clinical Course And30-Days Mortality In Patients With Pneumonia?, Razi̇ye Si̇nem Misirlioğlu, Ersi̇n Aksay, Emre Şanci, Kemal Can Tertemi̇z

Turkish Journal of Medical Sciences

Background/aim: While several different scoring systems aim to determine the clinical outcomes for patients with pneumonia, there is limited emphasis on the platelet count. This study investigated the relationships between thrombocyte count and 30-day mortality and complicated clinical course of patients with pneumonia. Materials and methods: This prospective cross-sectional study enrolled patients over 18 years old with a diagnosis of pneumonia in the emergency department for six months. The primary outcome was to establish the relationship between platelet count, mortality, complicated clinical course, and initial vital parameters on admission. The secondary outcome was comparing the platelet count with mortality and …


Hydroxychloroquine Plus Azithromycin And Early Hospital Admission Are Beneficial Incovid-19 Patients: Turkish Experience With Real-Life Data, Eli̇f Tanriverdi̇, Mustafa Çörtük, Bi̇nnaz Zeynep Yildirim, Efsun Gonca Uğur Chousein, Demet Turan, Hali̇t Çinarka, Mehmet Aki̇f Özgül, Erdoğan Çeti̇nkaya Jan 2021

Hydroxychloroquine Plus Azithromycin And Early Hospital Admission Are Beneficial Incovid-19 Patients: Turkish Experience With Real-Life Data, Eli̇f Tanriverdi̇, Mustafa Çörtük, Bi̇nnaz Zeynep Yildirim, Efsun Gonca Uğur Chousein, Demet Turan, Hali̇t Çinarka, Mehmet Aki̇f Özgül, Erdoğan Çeti̇nkaya

Turkish Journal of Medical Sciences

Background/aim: New treatment regimens for COVID-19, which has threatened the world recently, continue to be investigated. Although some of the treatments are promising, it is thought to be early to state that there is definitive treatment. Experiences and treatment protocol studies from treatment centers are still important. The aim of this study is to evaluate factors affecting the treatment process of the first cases followed in our clinic. Materials and methods: The consecutive hospitalized patients with COVID-19 pneumonia were analyzed in this retrospective and cross-sectional study. Data were recorded from the electronic and written files of patients. Results: Eighty-three patients …


Hepatitis A Susceptibility Parallels High Covid-19 Mortality, Fai̇k Sariali̇oğlu, Fatma Burcu Belen, Kadi̇r Mutlu Hayran Jan 2021

Hepatitis A Susceptibility Parallels High Covid-19 Mortality, Fai̇k Sariali̇oğlu, Fatma Burcu Belen, Kadi̇r Mutlu Hayran

Turkish Journal of Medical Sciences

Background/aim:COVID-19 has become the biggest health problem of this century. It has been hypothesized that immunity against hepatitis A virus (HAV) may provide protection from COVID- 19. Materials and methods: As of 10June 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead. This data was combined with the World Health Organization susceptibility classification on the worldwide prevalence of HAV, and the relationship between HAV susceptibility and COVID-19 mortality were analyzed. Results: When the data from 213 countries were analyzed, it was found that there was a significant increasing trend in COVID-19 mortality rates …


Clinical Characteristics And Risk Factors For 28-Day Mortality In Critically Ill Patients With Covid-19: A Retrospective Cohort Study, Mehmet Nuri̇ Yakar, Begüm Ergan, Bi̇şar Ergün, Murat Küçük, Ali̇ Cantürk, Mahmut Cem Ergon, Naci̇ye Si̇nem Gezer, Erdem Yaka, Bi̇lgi̇n Cömert, Ali̇ Necati̇ Gökmen Jan 2021

Clinical Characteristics And Risk Factors For 28-Day Mortality In Critically Ill Patients With Covid-19: A Retrospective Cohort Study, Mehmet Nuri̇ Yakar, Begüm Ergan, Bi̇şar Ergün, Murat Küçük, Ali̇ Cantürk, Mahmut Cem Ergon, Naci̇ye Si̇nem Gezer, Erdem Yaka, Bi̇lgi̇n Cömert, Ali̇ Necati̇ Gökmen

Turkish Journal of Medical Sciences

Background: To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around the world. Risk factors for mortality remain unclear. The primary aim was to determine the independent risk factors for 28-day mortality. Materials and Methods: In this retrospective cohort study, critically ill patients (≥ 18 years) who were admitted to the intensive care unit due to COVID-19 were included. Patient characteristics, laboratory data, radiologic findings, treatments, and complications were analyzed in the study. Results: A total of 249 patients (median age 71, 69.1% male) were included in the study. 28-day mortality was 67.9% (n = …


Incidence, Risk Factors, And Adverse Outcomes Of Acute Kidney Injury In Very Prematureneonates: A Single Center Experience, Nuran Üstün Jan 2021

Incidence, Risk Factors, And Adverse Outcomes Of Acute Kidney Injury In Very Prematureneonates: A Single Center Experience, Nuran Üstün

Turkish Journal of Medical Sciences

Background/aim: Acute kidney injury (AKI) is a serious morbidity in premature neonates. The aim of this study was to determine the incidence of AKI and to evaluate its impact on morbidity and mortality in very premature infants. Materials and methods: This retrospective cohort study was conducted in the neonatal intensive care unit (NICU). A total of 410 preterm infants who were born before 32 gestational weeks were screened and 318 were included in this analysis. AKI was defined according to the modified neonatal Kidney Disease: Improving Global Outcomes criteria. Results: The incidence of AKI was 32.1% (102/318). Regression analyses revealed …


Factors Affecting Mortality In Geriatric Patients Hospitalized With Covid-19, Rabi̇a Bağ Soytaş, Damla Ünal, Pinar Arman, Veysel Suzan, Tuğçe Emi̇roğlu Gedi̇k, Günay Can, Bora Korkmazer, Ridvan Karaali̇, Şermi̇n Börekçi̇, Mert Ahmet Kuşkucu, Hakan Yavuzer, Ülev Deni̇z Erdi̇nçler, Alper Döventaş Jan 2021

Factors Affecting Mortality In Geriatric Patients Hospitalized With Covid-19, Rabi̇a Bağ Soytaş, Damla Ünal, Pinar Arman, Veysel Suzan, Tuğçe Emi̇roğlu Gedi̇k, Günay Can, Bora Korkmazer, Ridvan Karaali̇, Şermi̇n Börekçi̇, Mert Ahmet Kuşkucu, Hakan Yavuzer, Ülev Deni̇z Erdi̇nçler, Alper Döventaş

Turkish Journal of Medical Sciences

Background/aim: We aimed to investigate the factors affecting the mortality of patients aged 65 years or older who were hospitalized with the diagnosis of new coronavirus pneumonia (COVID-19). Materials and methods: This is a retrospective study of patients 65 years old or older with COVID-19 who were hospitalized in İstanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty Hospital, between March 11 and May 28, 2020. Demographic, clinical, treatment, and laboratory data were extracted from electronic medical records. We used univariate and multivariate logistic regression methods to explore the risk factors for in-hospital death. Results: A total of 218 patients (112 men, 106 women) …


Evaluation Of Initial Chest Computed Tomography (Ct) Findings Of Covid-19pneumonia In 117 Deceased Patients: A Retrospective Study, Yasemi̇n Gündüz, Oğuz Karabay, Ali̇ Fuat Erdem, Erbi̇l Arik, Mehmet Hali̇l Öztürk Jan 2021

Evaluation Of Initial Chest Computed Tomography (Ct) Findings Of Covid-19pneumonia In 117 Deceased Patients: A Retrospective Study, Yasemi̇n Gündüz, Oğuz Karabay, Ali̇ Fuat Erdem, Erbi̇l Arik, Mehmet Hali̇l Öztürk

Turkish Journal of Medical Sciences

Background/aim: There is no study in the literature in which only chest computed tomography (CT) findings of deceased cases obtained at admission were examined, and the relationship between these findings and mortality was evaluated. Materials and methods: In this retrospective study, a total of 117 deceased patients with COVID-19 infection confirmed by positive polymerase chain reaction and undergone chest CT were enrolled. We evaluated initial chest CT findings and their relationship, location, prevalence, and the frequency with mortality. Results: The mean age of patients was 73 ±18 years; 71 of all patients were male and 46 were female. The predominant …


Impact Of Hospital-Acquired Acute Kidney Injury On Covid-19 Outcomes In Patients Withand Without Chronic Kidney Disease: A Multicenter Retrospective Cohort Study, Savaş Öztürk, Kenan Turgutalp, Mustafa Arici, Hakki Çeti̇nkaya, Mehmet Riza Altiparmak, Zeki̇ Aydin, Zeki̇ Soypaçaci, Feyza Bora, Ekrem Kara, Egemen Cebeci̇, Tuba Eli̇f Özler, Mürşi̇de Esra Dölarslan, Savaş Si̇pahi̇, Yavuz Ayar, İdri̇s Şahi̇n Jan 2021

Impact Of Hospital-Acquired Acute Kidney Injury On Covid-19 Outcomes In Patients Withand Without Chronic Kidney Disease: A Multicenter Retrospective Cohort Study, Savaş Öztürk, Kenan Turgutalp, Mustafa Arici, Hakki Çeti̇nkaya, Mehmet Riza Altiparmak, Zeki̇ Aydin, Zeki̇ Soypaçaci, Feyza Bora, Ekrem Kara, Egemen Cebeci̇, Tuba Eli̇f Özler, Mürşi̇de Esra Dölarslan, Savaş Si̇pahi̇, Yavuz Ayar, İdri̇s Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: Hospital-acquired acute kidney injury (HA-AKI) may commonly develop in Covid-19 patients and is expected to have higher mortality. There is little comparative data investigating the effect of HA-AKI on mortality of chronic kidney disease (CKD) patients and a control group of general population suffering from Covid-19. Materials and methods: HA-AKI development was assessed in a group of stage 3-5 CKD patients and control group without CKD among adult patients hospitalized for Covid-19. The role of AKI development on the outcome (in-hospital mortality and admission to the intensive care unit [ICU]) of patients with and without CKD was compared. Results: …


Mortality In Some Domesticated Pigeons (Columba Livia) From Jammu, India, Syed Mehmood, Nawab Nashiruddullah, Jafrin Ara Ahmed Jan 2021

Mortality In Some Domesticated Pigeons (Columba Livia) From Jammu, India, Syed Mehmood, Nawab Nashiruddullah, Jafrin Ara Ahmed

Turkish Journal of Veterinary & Animal Sciences

Although pigeons are reared for recreational purposes in Jammu region, disease occurrence is sparsely documented. Based on clinical signs, lesions and laboratory investigation, approximately 600 out of 4000 (15%) domestic pigeons were found to be disease affected. Necropsy of 60 birds was conducted to determine the cause of death. Haemoproteus columbae demonstrated within erythrocytes and various development stages in tissue and endothelial schizogony caused majority deaths due to pneumonia and hepatitis (45%) accompanied by severe vascular and tissue reaction. Newcastle disease (20%) confirmed by positive serum haemagglutination inhibition manifested in a severe neurological form with characteristic cerebral malacia and demyelination. …


The Effect Of Comorbidity On Mortality In Elderly Patients Undergoing Emergencyabdominal Surgery: A Systematic Review And Metaanalysis, Fadi̇me Çinar, Göknur Parlak, Fatma Eti̇ Aslan Jan 2021

The Effect Of Comorbidity On Mortality In Elderly Patients Undergoing Emergencyabdominal Surgery: A Systematic Review And Metaanalysis, Fadi̇me Çinar, Göknur Parlak, Fatma Eti̇ Aslan

Turkish Journal of Medical Sciences

Background/aim: With the increase in the elderly population, the elderly proportion needing emergency surgery is also increasing. Despite medical advances in surgery and anesthesia, negative postoperative outcomes and high mortality rates are still present in elderly patients undergoing emergency surgery. Comorbidities are described as the main determining factors in poor outcomes. In this metaanalysis, it was aimed to investigate the effect of comorbidity on mortality in elderly patients undergoing emergency abdominal surgery. Materials and methods: The studies published between 2010-2019 were scanned from databases of Google Scholar, Cinahl, Pub Med, Medline and Web of Science. Quality criteria proposed by Polit …