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Full-Text Articles in Medicine and Health Sciences
Producing A Subunit Vaccine For Porcine Epidemic Diarrhea Virus, Zayn Khamis
Producing A Subunit Vaccine For Porcine Epidemic Diarrhea Virus, Zayn Khamis
Electronic Thesis and Dissertation Repository
Porcine epidemic diarrhea virus (PEDv) causes disease and mortality to piglets worldwide. Most vaccines used to combat the disease have been ineffective live attenuated virus vaccines. The goal of this project was to produce a plant-made subunit vaccine based off the membrane protein of the virus. This is the first time this protein has been produced in plants. An elastin-like polypeptide fusion membrane protein accumulated up to 0.8 mg/g of fresh leaf weight when transiently expressed in Nicotiana benthamiana. Virus-like particles were also produced for the first time for PEDv, and were able to form with just the membrane …
Symptom Experience And Influenza-Like Illness In A Military Population, Monique Bouvier
Symptom Experience And Influenza-Like Illness In A Military Population, Monique Bouvier
Dissertations
AIMS: The primary objective of this study was to identify if symptom presentation expressed over the course of an influenza-like illness (ILI) can predict virus type by use of unsupervised machine learning. The secondary objective was to describe clinical characteristics of strain specific coronavirus. Finally, examine the psychometric properties of the Canadian Acute Respiratory Illness and Flu Scale (CARIFS).
BACKGROUND: ILI outbreaks have been a significant source of non-battle injury among military personnel. Many different viruses cause ILI, and it is difficult to determine which virus is causing the illness. Recent studies have examined the etiology and epidemiology of ILIs. …