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Full-Text Articles in Medicine and Health Sciences
The Relationships Between The Home Food Environment And Weight Status Among Children And Adolescents, Ages 6-17 Years, Martha J. Nepper
The Relationships Between The Home Food Environment And Weight Status Among Children And Adolescents, Ages 6-17 Years, Martha J. Nepper
Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research
The home food environment is an important setting in regard to a child’s dietary intake and the development of obesity, since 65% to 72% of daily calories are consumed in the home. Research is beginning to explore how the home food environment may influence children’s weight status. It is suggested that homes with healthy weight children are more likely to have healthier food options available and limit access to unhealthy foods. Prior research on the influence of the home food environment on children and adolescent’s weight status is not clear, as some researchers have found that the home food environment …
Suppression Of Nlrp3 Inflammasome By Γ-Tocotrienol Ameliorates Type 2 Diabetes, Yongeun Kim, Wei Wang, Meshail Okla, Inhae Kang, Regis Moreau, Soonkyu Chung
Suppression Of Nlrp3 Inflammasome By Γ-Tocotrienol Ameliorates Type 2 Diabetes, Yongeun Kim, Wei Wang, Meshail Okla, Inhae Kang, Regis Moreau, Soonkyu Chung
Department of Nutrition and Health Sciences: Faculty Publications
The Nod-like receptor 3 (NLRP3) inflammasome is an intracellular sensor that sets off the innate immune system in response to microbial-derived and endogenous metabolic danger signals. We previously reported that γ-tocotrienol (γT3) attenuated adipose tissue inflammation and insulin resistance in diet-induced obesity, but the underlying mechanism remained elusive. Here, we investigated the effects of γT3 on NLRP3 inflammasome activation and attendant consequences on type 2 diabetes. γT3 repressed inflammasome activation, caspase-1 cleavage, and interleukin (IL) 1β secretion in murine macrophages, implicating the inhibition of NLRP3 inflammasome in the anti-inflammatory and antipyroptotic properties of γT3. Furthermore, supplementation of leptin-receptor KO mice …