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Full-Text Articles in Medicine and Health Sciences

Titrating Clozapine Amidst Recommendations Proposing High Myocarditis Risk And Rapid Titrations, Jose De Leon, Y.-L. Tang, T. Baptista, D. Cohen, P. F. J. Schulte Oct 2015

Titrating Clozapine Amidst Recommendations Proposing High Myocarditis Risk And Rapid Titrations, Jose De Leon, Y.-L. Tang, T. Baptista, D. Cohen, P. F. J. Schulte

Psychiatry Faculty Publications

No abstract provided.


Clinical Applications Of A Combination Chemotherapy Using 8-Chloro Camp And 8-Chloro Adenosine, Erik Munoz, Andrea Saich, Andrew Cox, Yu-An Peter Chang May 2015

Clinical Applications Of A Combination Chemotherapy Using 8-Chloro Camp And 8-Chloro Adenosine, Erik Munoz, Andrea Saich, Andrew Cox, Yu-An Peter Chang

Student Scholar Symposium Abstracts and Posters

Dr. Cho-Chung from the NIH first thought to use halogenated cAMP derivatives as competitive inhibitors of cAMP to slow down cancer cell mitosis. While the iodine and bromine substituted versions showed very little therapeutic actions, 8-Chloro cAMP has been shown to have strong anti-cancer effects. This has been shown in the phase II clinical trials this drug has undergone. However, these trials have had issues with solubility and toxicity. The drug is similar to vitamin C and is excreted quickly. Scientists tried to overcome this by using a peristaltic pump to give patients a continuous dosage, but this proved too …


Albumin Administration In Patients With Spontaneous Bacterial Peritonitis At A Tertiary Hospital: A Retrospective Clinical Analysis, Padmavathi Mali, Rajan Kanth, Sudheer Muduganti Apr 2015

Albumin Administration In Patients With Spontaneous Bacterial Peritonitis At A Tertiary Hospital: A Retrospective Clinical Analysis, Padmavathi Mali, Rajan Kanth, Sudheer Muduganti

Journal of Patient-Centered Research and Reviews

Purpose

Albumin is recommended for the treatment of spontaneous bacterial peritonitis (SBP) in patients at high risk for mortality. We assessed adherence to guidelines for administration of albumin for SBP in clinical practice at a private tertiary care hospital.

Methods

A retrospective clinical analysis of all cases of SBP diagnosed at a tertiary referral center from January 1, 2006, to December 31, 2012, was performed. Patients were identified electronically and manually validated. The appropriateness of albumin administration for treatment of SBP was assessed in all patients in whom mortality risk could be established and separately for patients who did or …


Shoulder Pain And Dysfunction In Young Surf Lifesavers, Josh Carter, Nick Marshall, Allan Abbott Mar 2015

Shoulder Pain And Dysfunction In Young Surf Lifesavers, Josh Carter, Nick Marshall, Allan Abbott

Allan D. Abbott

Objectives: To determine the incidence and prevalence of significantly interrupting shoulder pain (SIP) in young surf lifesavers and to determine association with training dosage and the ‘combined elevation test’. Participants: 54 surf lifesavers aged 10e18 from the Gold Coast, Australia. Methods and outcome measures: Retrospective survey of SIP and training dosage. Cross-sectional measures of the combined elevation test. Design: Retrospective. Results: 56.5% of female surf lifesavers reported a history of SIP compared to males with 48.5%. Females had a higher combined elevation score compared to males, 28.32 ± SD 8.52 cm and 26.09 ± SD 6.64 cm, respectively. Young surf …