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Full-Text Articles in Medicine and Health Sciences

College Students' Communication About Nonmedical Use Of Prescription Stimulants: Applying The Theory Of Planned Behavior, Ana Andreoli, Darren Breese, Kylie Deschenes, Lindsey Sarver May 2015

College Students' Communication About Nonmedical Use Of Prescription Stimulants: Applying The Theory Of Planned Behavior, Ana Andreoli, Darren Breese, Kylie Deschenes, Lindsey Sarver

Student Scholar Symposium Abstracts and Posters

The study examines college students' communication surrounding nonmedical use of prescription stimulants (NPS). Using a hypothetical scenario, the researchers will employ the Theory of Planned Behavior to investigate if students' attitudes and perceived social norms affect their intent to intervene on behalf of a friend who is engaging in what they believe to be excessive NPS. College students’ will complete anonymous web-based surveys, reporting on each of the study variables as well as demographic information. Self-reports of both perceived and actual knowledge of engaging in NPS, as well as students' levels of communication health literacy, will also be collected as …


Analyzation Of Metabolic Reprogramming In Drug-Resistant Mcf-7 Cells, Derick Han, Ho Leung, Andrew Vo May 2015

Analyzation Of Metabolic Reprogramming In Drug-Resistant Mcf-7 Cells, Derick Han, Ho Leung, Andrew Vo

Student Scholar Symposium Abstracts and Posters

The Warburg effect states that cancer cells mainly receive their energy from anaerobic glycolysis. Thus, mitochondria play a different role in the metabolism of cancer cells as opposed to normal, healthy cells. In chemotherapy, there is always a chance of the cancer regressing. Making drug-resistant cancer cells to analyze their metabolism may change how cancer is treated. This study aimed to create drug-resistant MCF-7 cell lines with doxorubicin in order to determine the metabolic changes that have occurred in the process of becoming resistant to drug treatments.


Reliability Of Precision In Motion Software, Nicole Laura, Kristen Petrillo, Marybeth Grant-Beuttler, Richard Beuttler May 2015

Reliability Of Precision In Motion Software, Nicole Laura, Kristen Petrillo, Marybeth Grant-Beuttler, Richard Beuttler

Student Scholar Symposium Abstracts and Posters

Background: There is a current lack of affordable 3-D motion analysis systems available to physical therapists for documenting objective data.

Objective: Compare data from inexpensive 3-D motion capture system using the Kinect, to the Codamotion, a traditional active marker, motion analysis system. Determine data reliability.

Design: Reliability-method comparison study

Methods: Seventeen subjects (9 females, 8 males) were instructed to walk down marked runway, arms across chest while both systems recorded data. Data was collected with Kinect on the same and opposite side as the Coda. Kinect and Coda data were interpolated and normalized for comparison. A program for heel strike …


Efficacy Of The Picture Exchange Communication Systemin Children With Autism Spectrum Disorder, Reagan Blason May 2015

Efficacy Of The Picture Exchange Communication Systemin Children With Autism Spectrum Disorder, Reagan Blason

Student Scholar Symposium Abstracts and Posters

The increasing diagnoses of Autism Spectrum Disorder (ASD) each year affect many families worldwide and are a major concern to therapists, healthcare workers, and educators. Many children diagnosed with ASD will never go on to develop functional speech or will have limited communication, as well as impaired social-communication skills. Limited communication makes education and therapy difficult for these children and their caregivers. Language therapy and interventions aim to improve social-communication and speech in these children, so it is crucial to find the most efficient interventions. The Picture Exchange Communication System (PECS) is a common tool used to assist communication in …


Exploring Egr-1 As A Master Regulator Of Prostate Field Cancerization, Kristin Gabriel, Marco Bisoffi May 2015

Exploring Egr-1 As A Master Regulator Of Prostate Field Cancerization, Kristin Gabriel, Marco Bisoffi

Student Scholar Symposium Abstracts and Posters

Field cancerization denotes the presence of molecular aberrations (genetic, epigenetic, biochemical) in structurally intact cells residing in histologically normal tissues adjacent to tumors. Markers of field cancerization in prostate tissues have the potential to improve the clinical management of this malignancy through their potential to act as indicators of early disease and to serve as molecular targets for early intervention. However, for this, a detailed understanding of the functional pathways underlying field cancerization is necessary. We have recently identified four protein markers of prostate field cancerization, i.e. the key transcription factor early growth response 1 (EGR-1), the lipogenic enzyme fatty …


The Impact Of A 20% Vs. A 40% Caloric Restrictive Diet On Bone Mineral Density During The Growth Period In Male Rats, Kassandra Lee May 2015

The Impact Of A 20% Vs. A 40% Caloric Restrictive Diet On Bone Mineral Density During The Growth Period In Male Rats, Kassandra Lee

Student Scholar Symposium Abstracts and Posters

Purpose: The purpose of this study was to determine the impact of a 20% and a 40% caloric restrictive diet on bone mineral density (BMD) and bone strength in male rats during the growth period. Methods: 32 male rats were randomly divided into: control groups (C20, n=8 and C40, n=8), a group fed the 20% caloric restrictive diet (D20, n=8), and a group fed the 40% caloric restrictive diet (D40, n=8). An animal in the caloric restrictive diet group was matched and pair fed with an animal in the control group for 6 weeks. Each caloric restrictive diet contained additional …


#Narcissus, Lauren Potts May 2015

#Narcissus, Lauren Potts

Student Scholar Symposium Abstracts and Posters

My senior BFA exhibition is a project bringing awareness and reflection to the college subculture of drinking. I am creating a large installation (approx. 10x20ft) made out of over 4,000 red plastic cups in the shape of a Catholic Church altar. The cups are stacked and glued together in order to create patterns to separate the forms of the altar (three stairs, columns, the facade arches). The installation is shown at Chapman University's Guggenheim Gallery and must be site specific in order to reflect the nature of its existence and purpose. The installation reflects a parallel between forms of ritual: …


Puffs And Tufts: A Comparison Of Trichodesmium Colony Formations And Nutrient Availability Across The North Atlantic Ocean Using Remote Sensing Methods, Marc Rosenfield May 2015

Puffs And Tufts: A Comparison Of Trichodesmium Colony Formations And Nutrient Availability Across The North Atlantic Ocean Using Remote Sensing Methods, Marc Rosenfield

Student Scholar Symposium Abstracts and Posters

Trichodesmium, a genus of diazotrophic bacteria, has the capability and the population to produce a large percentage of the total oceanic N2-fixation. Though their population is known to be heavily dependent on two of the ocean’s largest limiting factors, phosphorus and iron concentrations, it is unknown what affect these factors have on the population. In this study two of the largest colony formations of Trichodesmium in the North Atlantic, tufts and puffs, are compared nutrient quality with respect to time and geographical location. Though very little nutrient in situ data was collected from the cruise, remote sensing data collected from …


Characterizing Psychological Management Practices Of College And University Athletic Trainers In Orange, California, Hannah L. Alexander, Paulina Tselikis, Michelle A. Cleary, Sara L. Nottingham, Jason Bennett May 2015

Characterizing Psychological Management Practices Of College And University Athletic Trainers In Orange, California, Hannah L. Alexander, Paulina Tselikis, Michelle A. Cleary, Sara L. Nottingham, Jason Bennett

Student Scholar Symposium Abstracts and Posters

An increase in the prevalence, types, and severity of psychological disorders among adolescents and young adults is being recognized. A multidisciplinary team approach to address mental health concerns among student-athletes, including well-developed referral and management plans, is important in the health care setting. Athletic trainers are often the first to notice subtle changes indicative of psychopathology, and have the ability to appropriately intervene and refer student-athletes as necessary. The purpose of this study was to investigate the psychological management practices of college and university athletic trainers in Orange, California. A descriptive exploratory online questionnaire was used to obtain information regarding …


Prostate Field Cancerization – Thinking Outside The Tumor, Dor Shoshan May 2015

Prostate Field Cancerization – Thinking Outside The Tumor, Dor Shoshan

Student Scholar Symposium Abstracts and Posters

Analysis of tumor adjacent tissue is assumed to reveal a temporal record of molecular pathways that define oncogenesis. The present study determines expression of the key transcription factor and potential marker of field cancerization early growth response 1 (EGR-1) in human prostate tissues derived from prostatectomies and biopsies. Expression was detected using immunofluorescence and quantified using ImageJ software. Accordingly, EGR-1 expression was similar in cancerous and in histologically normal adjacent tissues from prostatectomy and biopsy specimens. EGR-1 could be exploited as pre-surgical disease indicator in false negative biopsies, identify areas of repeat biopsy, and add molecular information to surgical margins.


Effects Of Human Recreational Activity On The Tameness Of Common Loons (Gavia Immer) In Northern Wisconsin, Seth Yund May 2015

Effects Of Human Recreational Activity On The Tameness Of Common Loons (Gavia Immer) In Northern Wisconsin, Seth Yund

Student Scholar Symposium Abstracts and Posters

The Common Loon (Gavia immer) is an aquatic diving bird that lives in freshwater habitats in Canada and the northern U.S.. Human activity on a loon’s resident lake may affect its fitness and behavior, yet few studies identify or quantify these effects. We modified existing techniques that measure escape distances in other species to measure tameness as the distance at which individual loons dove in response to human approach by canoe. Tameness was similar between pair members, suggesting that common lake conditions or the behavior of a mate might influence the behavior. Sex, size within sex, and human activity did …


Clinical Applications Of A Combination Chemotherapy Using 8-Chloro Camp And 8-Chloro Adenosine, Erik Munoz, Andrea Saich, Andrew Cox, Yu-An Peter Chang May 2015

Clinical Applications Of A Combination Chemotherapy Using 8-Chloro Camp And 8-Chloro Adenosine, Erik Munoz, Andrea Saich, Andrew Cox, Yu-An Peter Chang

Student Scholar Symposium Abstracts and Posters

Dr. Cho-Chung from the NIH first thought to use halogenated cAMP derivatives as competitive inhibitors of cAMP to slow down cancer cell mitosis. While the iodine and bromine substituted versions showed very little therapeutic actions, 8-Chloro cAMP has been shown to have strong anti-cancer effects. This has been shown in the phase II clinical trials this drug has undergone. However, these trials have had issues with solubility and toxicity. The drug is similar to vitamin C and is excreted quickly. Scientists tried to overcome this by using a peristaltic pump to give patients a continuous dosage, but this proved too …


The Effects Of A Caloric Restrictive Diet On Bone Mineral Density And Bone Strength In Male And Female Rats, Haley Folta May 2015

The Effects Of A Caloric Restrictive Diet On Bone Mineral Density And Bone Strength In Male And Female Rats, Haley Folta

Student Scholar Symposium Abstracts and Posters

The purpose of this study was to determine the existence of sex differences following a 40% caloric restrictive diet and its impact on tibial bone mineral density (BMD) and bone strength between male and female rats. Thirty-two, six-week old Sprague Dawley rats (16 males and 16 females) were randomly divided into an ad libitum fed control group (MC, n=8 and FC, n=8) and a pair fed diet group placed on the 40% caloric restriction (MD, n=8 and FD, n=8) for a 6 week period. The caloric restrictive diet was equivalent to the normal fed diet in vitamin and mineral content …


Effect Of Curcumin Analog Ca27 On Androgen Receptor Translocation In Prostate Cancer Cells, Lijah Vann Gardner May 2015

Effect Of Curcumin Analog Ca27 On Androgen Receptor Translocation In Prostate Cancer Cells, Lijah Vann Gardner

Student Scholar Symposium Abstracts and Posters

The androgen receptor (AR) plays an essential role in promoting the development and progression of metastatic prostate cancer and represents an important molecular target for therapeutic intervention. We have recently described a series of synthetic analogs of the natural product diferuloylmethane (curcumin), some of which induce the down-regulation of AR expression in prostate cancer cells by an as yet largely unknown mechanism of action. While such analogs may in the long term be lead structures for the development of therapeutic drugs, we hypothesize here that they represent ideal molecular probes to identify the mechanism(s) of action for AR down-regulation. We …