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Full-Text Articles in Medicine and Health Sciences

Assessing Plasticity : The Populations Responsible For The Epithelial Engraftment On Marrow-Derived Cells, Justin Brent Cohen Sep 2010

Assessing Plasticity : The Populations Responsible For The Epithelial Engraftment On Marrow-Derived Cells, Justin Brent Cohen

Yale Medicine Thesis Digital Library

Bone marrow-derived cells (BMDCs) have significant plasticity allowing them to give rise to various non-hematopoietic cell types including epithelial cells of the lung, liver, gut, and skin. These findings offer tremendous possibilities for the use of cell therapy to treat tissue injury and disease. However, the specific populations of cells responsible for this phenomenon are still unclear with considerable controversy over the mechanism of this transformation. In this study, we sought to compare the epithelial engraftment ability of two populations enriched for hematopoietic stem cells (HSCs), specifically the fractionated, lineage-depleted, and homed subset (FLH) and the lineage-Sca-1+c-Kit+ sorted population (LSK), …


Application Of Mechanical Vibration To Modulate Orthodontic Tooth Movement (Otm) In Mice, Andrew Rummel Apr 2010

Application Of Mechanical Vibration To Modulate Orthodontic Tooth Movement (Otm) In Mice, Andrew Rummel

Master's Theses (2009 -)

Purpose: The purpose of this study was to use micro CT to evaluate the effect of mechanical vibration on orthodontic tooth movement (OTM) in mice. Materials and Methods: Thirty-six mice (C57BL/6, 20 weeks old, male) were randomly divided into four groups: spring/vibration (SV), spring only (S), vibration only (V), control (C). A nickel-titanium (NiTi) spring was fabricated and inserted bilaterally between the maxillary 1st molars, delivering an initial force of 20 grams. From day 0, mechanical vibration (4Hz frequency, 20micron displacement, 5 min per session duration) was applied to the left maxillary 1st molar every three days for 3 weeks …


Effect Of Polyunsaturated Fatty Acids On Murine Thymocytes, Aparna Prasad Jan 2010

Effect Of Polyunsaturated Fatty Acids On Murine Thymocytes, Aparna Prasad

Legacy Theses & Dissertations (2009 - 2024)

Several reports suggest that the relative beneficial effect of consumption of omega-3 as