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Full-Text Articles in Medicine and Health Sciences
Augmentation Of Macular Pigment Following Supplementation With All Three Macular Carotenoids: An Exploratory Study, Eithne Connolly, Stephen Beatty, David Thurnham, James Loughman, Alan Howard, Jim Stack, John Nolan
Augmentation Of Macular Pigment Following Supplementation With All Three Macular Carotenoids: An Exploratory Study, Eithne Connolly, Stephen Beatty, David Thurnham, James Loughman, Alan Howard, Jim Stack, John Nolan
Articles
Purpose:At the macula, the carotenoids meso-zeaxanthin (MZ), lutein (L), and zeaxanthin (Z) are collectively referred to as macular pigment (MP). This study was designed to measure serum and macular responses to a macular carotenoid formulation. Materials and Methods:Ten subjects were recruited into this study (five normal and five with early age-related macular degeneration [AMD]). Subjects were instructed to consume a formulation containing 7.3mg of MZ, 3.7mg of L, and 0.8mg of Z everyday over an eight-week period. The spatial profile of MP optical density (i.e., MPOD at 0.25°, 0.5°, 1°, and 1.75°) was measured using customized heterochromatic flicker photometry, and …
Macular Pigment And Its Contribution To Visual Performance And Experience [El Pigmento Macular Y Su Contribución Al Rendimiento Y Experiencia Visuals], James Loughman, Peter Davison, John M. Nolan, Mukunda C. Akkali, Stephen Beatty
Macular Pigment And Its Contribution To Visual Performance And Experience [El Pigmento Macular Y Su Contribución Al Rendimiento Y Experiencia Visuals], James Loughman, Peter Davison, John M. Nolan, Mukunda C. Akkali, Stephen Beatty
Articles
There is now a consensus, based on histological, biochemical and spectral absorption data, that the yellow colour observed at the macula lutea is a consequence of the selective accumulation of dietary xanthophylls in the central retina of the living eye. Scientific research continues to explore the function(s) of MP in the human retina, with two main hypotheses premised on its putative capacity to (1) protect the retina from (photo)-oxidative damage by means of its optical filtration and/or antioxidant properties, the so-called protective hypothesis and (2) influence the quality of visual performance by means of selective short wavelength light absorption prior …