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Full-Text Articles in Medicine and Health Sciences
Effects Of Early Gestation Gh Administration On Placental And Fetal Development In Sheep., Casey D Wright, Ryan J Orbus, Timothy Regnault, Russell V Anthony
Effects Of Early Gestation Gh Administration On Placental And Fetal Development In Sheep., Casey D Wright, Ryan J Orbus, Timothy Regnault, Russell V Anthony
Paediatrics Publications
Ovine GH (oGH) is synthesized in placental tissue during maximal placental growth and development. Our objectives were to localize oGH mRNA in the placenta, and study the impact of exogenous GH on twin pregnancies during the normal window (35-55 days of gestational age; dGA) of placental expression. In situ hybridization localized oGH mRNA in uterine luminal epithelium but not in tissues of fetal origin. While maternal GH and IGF-I concentrations were increased (P
Placental Heat Shock Protein 70 Overexpression Confers Resistance Against Oxidative Stress In Preeclampsia, Ekambaram Padmini, Bose Vijaya Geetha
Placental Heat Shock Protein 70 Overexpression Confers Resistance Against Oxidative Stress In Preeclampsia, Ekambaram Padmini, Bose Vijaya Geetha
Turkish Journal of Medical Sciences
Aims: Preeclampsia is a hypertensive disorder of human pregnancy and a leading cause of premature delivery and fetal growth retardation. The purpose of this study was to evaluate the expression of heat shock protein 70 (HSP70), both constitutive (HSC70) and induced (HSP70) forms, along with oxidative stress status in the placental tissues of normotensive (control group) and preeclamptic pregnancies. Materials and Methods: Placental samples were collected after delivery from normotensive pregnancies and preeclamptic patients (n = 20, each). Lipid peroxidation product malondialdehyde (MDA) and nitrite and nitrate levels, along with antioxidants such as superoxide dismutase (SOD) and glutathione peroxidase (GPx) …
The Relationship Between Pro-Inflammatory Cytokines, Prostaglandins, And Fetal Hypothalamic-Pituitary-Adrenal Axis Activation In Mares With Infective Pre-Term Delivery, Sara K. Lyle
LSU Doctoral Dissertations
Ascending placentitis is a significant cause of abortions, stillbirths, and perinatal loss in horses. A technique for laparoscopic-guided catheterization of the allantoic space was developed and utilized in an experimental model of streptococcal infective pre-term delivery in pony mares. Mares received either 1 x 107 CFU live S. zooepidemicus (n=3), 5.1 x 108 CFU live S. zooepidemicus (n=1), 1 x 107 heat-killed S. zooepidemicus (n=3), 1 mL sterile PBS (n=3). Sham control mares did not receive a transcervical inoculation (n=3). One mare not instrumented with an allantoic catheter received 5.1 x 108 CFU live S. zooepidemicus. Mares with spontaneous abortion …
Structural Changes Of Placenta In Preeclamptic Patients: Light And Electron Microscopic Study, Reda Awadallah Saleh, Mohamed Abdel Monem Dkhil
Structural Changes Of Placenta In Preeclamptic Patients: Light And Electron Microscopic Study, Reda Awadallah Saleh, Mohamed Abdel Monem Dkhil
Turkish Journal of Medical Sciences
Background: Preeclampsia is a disorder that occurs only during pregnancy and the postpartum period and affects both the mother and the unborn baby. It is a rapidly progressive condition characterized by high blood pressure and the presence of protein in the urine. The study was designed to investigate the histological and ultrastructural changes in placentas from pregnancies complicated by preeclampsia. Methods: Paraffin sections from placenta biopsies were prepared for light microscopic examination. For ultrastructural examination, biopsies were prepared and examined by digital scanning electron microscope. Results: Light microscopic examinations showed that the nuclei of syncytiotrophoblast layer were aggregated into clusters …