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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2007

Wright State University

Anesthesiology

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Full-Text Articles in Medicine and Health Sciences

Implementation Of An Antibiotic Nomogram Improves Postoperative Antibiotic Utilization And Safety In Patients Undergoing Coronary Artery Bypass Grafting, Thomas J. Papadimos, Jennifer L. Grabarczyk, Daniel F. Grum, James P. Hofmann, Alan P. Marco, Sadik A. Khuder Jan 2007

Implementation Of An Antibiotic Nomogram Improves Postoperative Antibiotic Utilization And Safety In Patients Undergoing Coronary Artery Bypass Grafting, Thomas J. Papadimos, Jennifer L. Grabarczyk, Daniel F. Grum, James P. Hofmann, Alan P. Marco, Sadik A. Khuder

Anesthesiology Faculty Publications

Background

Routine, initial, empiric vancomycin dosing by clinicians in postoperative coronary artery bypass grafting (CABG) patients was identified as a potential patient safety issue in the Cardiovascular Intensive Care Unit (CVICU) because the rate of postoperative acute renal insufficiency (ARI) and average patient Body Mass Index (BMI) > 35 kg/m2 were significantly higher in our institution than those of the Society of Thoracic Surgeons (STS) database. A vancomycin dosing nomogram was derived from the local patient population in the attempt to improve patient safety by convincing clinicians to use an evidence-based approach to vancomycin prescription.

Methods

We analyzed two different treatment …