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Full-Text Articles in Medicine and Health Sciences

Integrative Medicine And Cancer: Treatment Strategies, Clinic Staff Aug 2006

Integrative Medicine And Cancer: Treatment Strategies, Clinic Staff

Topics in Integrative Medicine

Presents a model and discussion of an integrative medicine approach to cancer which includes conventional treatment, diet, nutraceuticals, lifestyle factors, psychosocial-spiritual factors, and constitutional therapies.


Agents Promoting Cellular Differentiation, Clinic Staff Jul 2006

Agents Promoting Cellular Differentiation, Clinic Staff

Topics in Integrative Medicine

Discusses the concept of cellular differentiation as an important anti-cancer mechanism and the data that supports the use of retinoids, vitamin D and other products for this purpose.


The Use Of Fatty Acids In Malignancies, Clinic Staff Jul 2006

The Use Of Fatty Acids In Malignancies, Clinic Staff

Topics in Integrative Medicine

Fatty acids have specific biological response modifier effects. These effects are discussed in relation to anti-inflammatory properties, and for the prevention and adjuvant treatment of cancer.


Integrative Medicine Approach To Colon Cancer, Clinic Staff Jul 2006

Integrative Medicine Approach To Colon Cancer, Clinic Staff

Topics in Integrative Medicine

Illustrates the principles and practice of Integrative Medicine in the treatment of colon cancer.


Milk Thistle (Silybum Marianum), Clinic Staff Jul 2006

Milk Thistle (Silybum Marianum), Clinic Staff

Topics in Integrative Medicine

Milk thistle is a commonly used herb for hepatic function and disorders. The evidence for its effects in liver disease is presented, as well as its potential use in cancer treatment.


The Use Of Mushroom Preparations In Malignancies, Clinic Staff Jul 2006

The Use Of Mushroom Preparations In Malignancies, Clinic Staff

Topics in Integrative Medicine

Medicinal mushrooms have been recommended for centuries in Asia. Specific types of mushrooms are presented, as well as evidence for their immunopotentiating effects and their use as adjuvant therapy for specific types of cancer.


Innate Antiviral Response Targets Hiv-1 Release By The Induction Of Ubiquitin-Like Protein Isg15, Atsushi Okumura, Gengshi Lu, Ian Pitha-Rowe, Paula M. Pitha Jan 2006

Innate Antiviral Response Targets Hiv-1 Release By The Induction Of Ubiquitin-Like Protein Isg15, Atsushi Okumura, Gengshi Lu, Ian Pitha-Rowe, Paula M. Pitha

Dartmouth Scholarship

The goal of this study was to elucidate the molecular mechanism by which type I IFN inhibits assembly and release of HIV-1 virions. Our study revealed that the IFN-induced ubiquitin-like protein ISG15 mimics the IFN effect and inhibits release of HIV-1 virions without having any effect on the synthesis of HIV-1 proteins in the cells. ISG15 expression specifically inhibited ubiquitination of Gag and Tsg101 and disrupted the interaction of the Gag L domain with Tsg101, but conjugation of ISG15 to Gag or Tsg101 was not detected. The inhibition of Gag-Tsg101 interaction was also detected in HIV-1 infected, IFN-treated cells. Elimination …