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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
An Assessment Of Epidural Ketamine For Hindlimb Anesthesia In Dogs, Somsak Wattananit, Marissak Kalpravidh
An Assessment Of Epidural Ketamine For Hindlimb Anesthesia In Dogs, Somsak Wattananit, Marissak Kalpravidh
The Thai Journal of Veterinary Medicine
The effect of epidural ketamine was studied in 20 experimental dogs premedicated with 0.04 mg/kg atropine and 2 mg/kg xylazine, given intramuscularly along with 0.2 mg/kg acepromazine given intravenously. All dogs received, epidurally, 2 mg/kg ketamine diluted in 0.9% normal saline (NSS) in a volume of 1 ml/ 4.5 kg and, one week or more before, or later, 1 ml/ 4.5 kg NSS without ketamine as a control. Animal response to pain stimulation was evaluated before, and during a surgical approach on the medial aspect of the tibia. The respiratory rates, heart rates and arterial blood pressures were measured before …
Autogenous Ilial Grafting Of Mandibles In Dogs, Chanin Kalpravidh, Atichat Brahmasa, Sumolya Kanchanapangka, Marissak Kalpravidh
Autogenous Ilial Grafting Of Mandibles In Dogs, Chanin Kalpravidh, Atichat Brahmasa, Sumolya Kanchanapangka, Marissak Kalpravidh
The Thai Journal of Veterinary Medicine
An autogenous ilial graft was experimentally used for grafting the mandibles of 6 mixed-breed dogs, aged 1 to 5 years. To prepare the recipient bed, the mandibular shaft, under the fourth premolar tooth, was cut 2 cm deep and removed with the tooth. An ilial graft, the same size as the excised mandibular shaft, was harvested from the dorsal iliac crest of the same dog. The graft was then seated in the recipient bed and fixed to the mandible by a plastic bone plate and screws. Bone union was evaluated radiographically and histologically. The grafted sites of all dogs were …
A Retrospective Study Of The Treatment Of Paraplegic Dogs, Marissak Kalpravidh
A Retrospective Study Of The Treatment Of Paraplegic Dogs, Marissak Kalpravidh
The Thai Journal of Veterinary Medicine
The case records of 11 dogs recovering from paraplegia, caused by vertebral fracture, vertebral luxation, spondylosis deformans or intervertebral disk protrusion, were studied. The dogs were examined and treated at the animal hospital of the Faculty of Veterinary Science, Chulalongkorn University from June 2000 to October 2004. Upon presentation, all dogs were paraplegic and had weak superficial or deep pain sensations. Only 9 dogs had voluntary motor function in their hindlimbs or tails. Two dogs received both surgical and medical treatment, while the others received only medical treatment, consisting of the administrations of corticosteroids, aescin, vitamin B1 and antibiotics for …
Endothelial-Specific Expression Of Caveolin-1 Impairs Microvascular Permeability And Angiogenesis, Philip M. Bauer, Jun Yu, Yan Chen, Reed Hickey, Pascal N. Bernatchez, Robin Looft-Wilson, Yan Huang, Frank Giordano, Radu V. Stan, William C. Sessa
Endothelial-Specific Expression Of Caveolin-1 Impairs Microvascular Permeability And Angiogenesis, Philip M. Bauer, Jun Yu, Yan Chen, Reed Hickey, Pascal N. Bernatchez, Robin Looft-Wilson, Yan Huang, Frank Giordano, Radu V. Stan, William C. Sessa
Dartmouth Scholarship
The functions of caveolae and/or caveolins in intact animals are beginning to be explored. Here, by using endothelial cell-specific transgenesis of the caveolin-1 (Cav-1) gene in mice, we show the critical role of Cav-1 in several postnatal vascular paradigms. First, increasing levels of Cav-1 do not increase caveolae number in the endothelium in vivo. Second, despite a lack of quantitative changes in organelle number, endothelial-specific expression of Cav-1 impairs endothelial nitric oxide synthase activation, endothelial barrier function, and angiogenic responses to exogenous VEGF and tissue ischemia. In addition, VEGF-mediated phosphorylation of Akt and its substrate, endothelial nitric oxide synthase, were …