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Effect Of Propranolol On Tmd Pain, Kanokporn Bhalang, Venus Khemkhun, Apinya Srilekarat, Lakana Luangjarmekorn

Chulalongkorn University Dental Journal

Objective The aim of this study was to test whether propranolol, a non selective beta-adrenergic receptor blocker, can reduce clinical pain of patients with Temporomandibular Disorders (TMD). Materials and methods Four TMD subjects received 2 weeks of propranolol (20 mg/day for the first week and 40 mg/day for the second week), followed by a 2-week washout period and 2 weeks of placebo tablets. Pain ratings (average pain, highest pain, lowest pain, and percentage of the time that subjects had pain) were recorded daily. All subjects and the investigator were blinded to the type of medication the subjects took at each …